Structural insights from GRP78-NF-κB binding interactions: A computational approach to understand a possible neuroprotective pathway in brain injuries

Journal of Theoretical Biology

Volumn 345, Issue , 2014, Pages 43-51

  Ávila, Marco Fidel ^a   Torrente, Daniel ^a   Cabezas, Ricardo ^a   Morales, Ludis ^a   García Segura, Luis Miguel ^b   Gonzalez, Janneth ^a   Barreto, George E ^a  

^a PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

^b INSTITUTO CAJAL   (Spain)

Author keywords

Brain damage; Neuroprotection; NF B regulation; Protein interaction

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

AMINO ACID; BRAIN; GENE EXPRESSION; HOMEOSTASIS; INJURY; PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; BRAIN INJURY; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; COMPLEX FORMATION; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NEUROPATHOLOGY; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; STATIC ELECTRICITY; STATISTICAL ANALYSIS; STRUCTURE ACTIVITY RELATION;

BRAIN DAMAGE; NEUROPROTECTION; NF-ΚB REGULATION; PROTEIN INTERACTION;

BRAIN INJURIES; COMPUTATIONAL BIOLOGY; HEAT-SHOCK PROTEINS; HUMANS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; NF-KAPPA B; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; STATIC ELECTRICITY;

EID: 84891645473     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2013.12.010     Document Type: Article

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