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Volumn 15, Issue 1, 2014, Pages 361-376

Chemokine receptors in epithelial ovarian cancer

Author keywords

Angiogenesis; Chemokine receptor; Immune response; Invasion; Metastasis; Migration; Ovarian carcinoma; Proliferation

Indexed keywords

CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR4; EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; LYMPHOTACTIN; MARAVIROC; MITOGEN ACTIVATED PROTEIN KINASE; PLERIXAFOR; PROSTAGLANDIN E2;

EID: 84891644299     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15010361     Document Type: Review
Times cited : (23)

References (114)
  • 2
    • 33947313964 scopus 로고    scopus 로고
    • American Cancer Society, American Cancer Society: Atlanta, GA, USA
    • American Cancer Society. American Cancer Society Cancer Facts & Figures 2013; American Cancer Society: Atlanta, GA, USA, 2013.
    • (2013) American Cancer Society Cancer Facts & Figures 2013
  • 3
    • 19744368302 scopus 로고    scopus 로고
    • Cancer of the ovary
    • Cannistra, S.A. Cancer of the ovary. N. Engl. J. Med. 2004, 351, 2519-2529.
    • (2004) N. Engl. J. Med , vol.351 , pp. 2519-2529
    • Cannistra, S.A.1
  • 4
    • 1842529995 scopus 로고    scopus 로고
    • Ovarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers
    • Burleson, K.M.; Casey, R.C.; Skubitz, K.M.; Pambuccian, S.E.; Oegema, T.R., Jr.; Skubitz, A.P. Ovarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers. Gynecol. Oncol. 2004, 93, 170-181.
    • (2004) Gynecol. Oncol , vol.93 , pp. 170-181
    • Burleson, K.M.1    Casey, R.C.2    Skubitz, K.M.3    Pambuccian, S.E.4    Oegema Jr., T.R.5    Skubitz, A.P.6
  • 5
    • 0035138697 scopus 로고    scopus 로고
    • CD44 and beta1 integrins mediate ovarian carcinoma cell migration toward extracellular matrix proteins
    • Casey, R.C.; Skubitz, A.P. CD44 and beta1 integrins mediate ovarian carcinoma cell migration toward extracellular matrix proteins. Clin. Exp. Metastasis 2000, 18, 67-75.
    • (2000) Clin. Exp. Metastasis , vol.18 , pp. 67-75
    • Casey, R.C.1    Skubitz, A.P.2
  • 6
    • 77956495728 scopus 로고    scopus 로고
    • Ovarian cancer development and metastasis
    • Lengyel, E. Ovarian cancer development and metastasis. Am. J. Pathol. 2010, 177, 1053-1064.
    • (2010) Am. J. Pathol , vol.177 , pp. 1053-1064
    • Lengyel, E.1
  • 7
    • 0038024615 scopus 로고    scopus 로고
    • The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
    • Fredriksson, R.; Lagerström, M.C.; Lundin, L.G.; Schiöth, H.B. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol. Pharmacol. 2003, 63, 1256-1272.
    • (2003) Mol. Pharmacol , vol.63 , pp. 1256-1272
    • Fredriksson, R.1    Lagerström, M.C.2    Lundin, L.G.3    Schiöth, H.B.4
  • 8
    • 17844400914 scopus 로고    scopus 로고
    • The repertoire of G-protein-coupled receptors in fully sequenced genomes
    • Fredriksson, R.; Schiöth, H.B. The repertoire of G-protein-coupled receptors in fully sequenced genomes. Mol. Pharmacol. 2005, 67, 1414-1425.
    • (2005) Mol. Pharmacol , vol.67 , pp. 1414-1425
    • Fredriksson, R.1    Schiöth, H.B.2
  • 10
    • 34147137118 scopus 로고    scopus 로고
    • Seven transmembrane receptors: Something old, something new
    • Lefkowitz, R.J. Seven transmembrane receptors: Something old, something new. Acta Physiol. (Oxf.) 2007, 190, 9-19.
    • (2007) Acta Physiol. (Oxf.) , vol.190 , pp. 9-19
    • Lefkowitz, R.J.1
  • 11
    • 0028174033 scopus 로고
    • Fingerprinting G-protein-coupled receptors
    • Attwood, T.K.; Findlay, J.B. Fingerprinting G-protein-coupled receptors. Protein Eng. 1994, 7, 195-203.
    • (1994) Protein Eng , vol.7 , pp. 195-203
    • Attwood, T.K.1    Findlay, J.B.2
  • 12
    • 0028338534 scopus 로고
    • GCRDb: A G-protein-coupled receptor database
    • Kolakowski, L.F. GCRDb: A G-protein-coupled receptor database. Recept. Channels 1994, 2, 1-7.
    • (1994) Recept. Channels , vol.2 , pp. 1-7
    • Kolakowski, L.F.1
  • 14
    • 0037126208 scopus 로고    scopus 로고
    • Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands
    • doi:10.1186/gb-2002-3-11-research0063
    • Joost, P.; Methner, A. Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands. Genome Biol. 2002, 3, doi:10.1186/gb-2002-3-11-research0063.
    • (2002) Genome Biol , pp. 3
    • Joost, P.1    Methner, A.2
  • 17
    • 84867876983 scopus 로고    scopus 로고
    • Function, diversity and therapeutic potential of the N-terminal domain of human chemokine receptors
    • Szpakowska, M.; Fievez, V.; Arumugan, K.; van Nuland, N.; Schmit, J.C.; Chevigné, A. Function, diversity and therapeutic potential of the N-terminal domain of human chemokine receptors. Biochem. Pharmacol. 2012, 84, 1366-1380.
    • (2012) Biochem. Pharmacol , vol.84 , pp. 1366-1380
    • Szpakowska, M.1    Fievez, V.2    Arumugan, K.3    van Nuland, N.4    Schmit, J.C.5    Chevigné, A.6
  • 19
    • 0036178483 scopus 로고    scopus 로고
    • Structure, function, and inhibition of chemokines
    • Fernandez, E.J.; Lolis, E. Structure, function, and inhibition of chemokines. Annu. Rev. Pharmacol. Toxicol. 2002, 42, 469-499.
    • (2002) Annu. Rev. Pharmacol. Toxicol , vol.42 , pp. 469-499
    • Fernandez, E.J.1    Lolis, E.2
  • 20
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: A new classification system and their role in immunity
    • Zlotnik, A.; Yoshie, O. Chemokines: A new classification system and their role in immunity. Immunity 2000, 12, 121-127.
    • (2000) Immunity , vol.12 , pp. 121-127
    • Zlotnik, A.1    Yoshie, O.2
  • 21
    • 80051790554 scopus 로고    scopus 로고
    • The role of chemokines and their receptors in angiogenesis
    • Kiefer, F.; Siekmann, A.F. The role of chemokines and their receptors in angiogenesis. Cell Mol. Life Sci. 2011, 68, 2811-2830.
    • (2011) Cell Mol. Life Sci , vol.68 , pp. 2811-2830
    • Kiefer, F.1    Siekmann, A.F.2
  • 23
    • 0029761071 scopus 로고    scopus 로고
    • The amino-terminal extracellular domain of the MCP-1 receptor, but not the RANTES/MIP-1alpha receptor, confers chemokine selectivity. Evidence for a two-step mechanism for MCP-1 receptor activation
    • Monteclaro, F.S.; Charo, I.F. The amino-terminal extracellular domain of the MCP-1 receptor, but not the RANTES/MIP-1alpha receptor, confers chemokine selectivity. Evidence for a two-step mechanism for MCP-1 receptor activation. J. Biol. Chem. 1996, 271, 19084-19092.
    • (1996) J. Biol. Chem , vol.271 , pp. 19084-19092
    • Monteclaro, F.S.1    Charo, I.F.2
  • 26
    • 65549114131 scopus 로고    scopus 로고
    • Characterization of chemokine receptor CXCR2 interacting proteins using a proteomics approach to define the CXCR2 chemosynapse
    • Raman, D.; Neel, N.F.; Sai, J.; Mernaugh, R.L.; Ham, A.J.; Richmond, A.J. Characterization of chemokine receptor CXCR2 interacting proteins using a proteomics approach to define the CXCR2 "chemosynapse". Methods Enzymol. 2009, 460, 315-330.
    • (2009) Methods Enzymol , vol.460 , pp. 315-330
    • Raman, D.1    Neel, N.F.2    Sai, J.3    Mernaugh, R.L.4    Ham, A.J.5    Richmond, A.J.6
  • 27
    • 77956325999 scopus 로고    scopus 로고
    • LIM and SH3 protein-1 modulates CXCR2-mediated cell migration
    • Raman, D.; Sai, J.; Neel, N.F.; Chew, C.S.; Richmond, A. LIM and SH3 protein-1 modulates CXCR2-mediated cell migration. PLoS One 2010, 5, e10050.
    • (2010) PLoS One , vol.5
    • Raman, D.1    Sai, J.2    Neel, N.F.3    Chew, C.S.4    Richmond, A.5
  • 28
    • 0031475028 scopus 로고    scopus 로고
    • Receptors induce chemotaxis by releasing the betagamma subunit of Gi, not by activating Gq or Gs
    • Neptune, E.R.; Bourne, H.R. Receptors induce chemotaxis by releasing the betagamma subunit of Gi, not by activating Gq or Gs. Proc. Natl. Acad. Sci. USA 1997, 94, 14489-14494.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14489-14494
    • Neptune, E.R.1    Bourne, H.R.2
  • 29
    • 79955476625 scopus 로고    scopus 로고
    • Overcoming hurdles in developing successful drugs targeting chemokine receptors
    • Schall, T.J.; Proudfoot, A.E. Overcoming hurdles in developing successful drugs targeting chemokine receptors. Nat. Rev. Immunol. 2011, 11, 355-363.
    • (2011) Nat. Rev. Immunol , vol.11 , pp. 355-363
    • Schall, T.J.1    Proudfoot, A.E.2
  • 30
    • 27144548417 scopus 로고    scopus 로고
    • Dimerization of chemokine receptors and its functional consequences
    • Springael, J.Y.; Urizar, E.; Parmentier, M. Dimerization of chemokine receptors and its functional consequences. Cytokine Growth Factor Rev. 2005, 16, 611-623.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 611-623
    • Springael, J.Y.1    Urizar, E.2    Parmentier, M.3
  • 32
    • 0346056873 scopus 로고    scopus 로고
    • Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor
    • Chen, C.; Li, J.; Bot, G.; Szabo, I.; Rogers, T.J.; Liu-Chen, L.Y. Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor. Eur. J. Pharmacol. 2004, 483, 175-186.
    • (2004) Eur. J. Pharmacol , vol.483 , pp. 175-186
    • Chen, C.1    Li, J.2    Bot, G.3    Szabo, I.4    Rogers, T.J.5    Liu-Chen, L.Y.6
  • 33
    • 14244254277 scopus 로고    scopus 로고
    • Platelet factor 4 and interleukin-8 CXC chemokine heterodimer formation modulates function at the quaternary structural level
    • Nesmelova, I.V.; Sham, Y.; Dudek, A.Z.; van Eijk, L.I.; Wu, G.; Slungaard, A.; Mortari, F.; Griffioen, A.W.; Mayo, K.H. Platelet factor 4 and interleukin-8 CXC chemokine heterodimer formation modulates function at the quaternary structural level. J. Biol. Chem. 2005, 280, 4948-4958.
    • (2005) J. Biol. Chem , vol.280 , pp. 4948-4958
    • Nesmelova, I.V.1    Sham, Y.2    Dudek, A.Z.3    van Eijk, L.I.4    Wu, G.5    Slungaard, A.6    Mortari, F.7    Griffioen, A.W.8    Mayo, K.H.9
  • 34
    • 15044365682 scopus 로고    scopus 로고
    • CXCR4 activation induces epidermal growth factor receptor transactivation in an ovarian cancer cell line
    • Porcile, C.; Bajetto, A.; Barbero, S.; Pirani, P.; Schettini, G. CXCR4 activation induces epidermal growth factor receptor transactivation in an ovarian cancer cell line. Ann. N. Y. Acad. Sci. 2004, 1030, 162-169.
    • (2004) Ann. N. Y. Acad. Sci , vol.1030 , pp. 162-169
    • Porcile, C.1    Bajetto, A.2    Barbero, S.3    Pirani, P.4    Schettini, G.5
  • 35
    • 24944553762 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation
    • Porcile, C.; Bajetto, A.; Barbieri, F.; Barbero, S.; Bonavia, R.; Biglieri, M.; Pirani, P.; Florio, T.; Schettini, G. Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation. Exp. Cell. Res. 2005, 308, 241-253.
    • (2005) Exp. Cell. Res , vol.308 , pp. 241-253
    • Porcile, C.1    Bajetto, A.2    Barbieri, F.3    Barbero, S.4    Bonavia, R.5    Biglieri, M.6    Pirani, P.7    Florio, T.8    Schettini, G.9
  • 36
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D.; Weinberg, R.A. Hallmarks of cancer: The next generation. Cell 2011, 144, 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 38
    • 84867630229 scopus 로고    scopus 로고
    • Revisiting the complexity of the ovarian cancer microenvironment-Clinical implications for treatment strategies
    • Musrap, N.; Diamandis, E.P. Revisiting the complexity of the ovarian cancer microenvironment-Clinical implications for treatment strategies. Mol. Cancer Res. 2012, 10, 1254-1264.
    • (2012) Mol. Cancer Res , vol.10 , pp. 1254-1264
    • Musrap, N.1    Diamandis, E.P.2
  • 39
    • 84870313971 scopus 로고    scopus 로고
    • Angiogenesis: A promising therapeutic target for ovarian cancer
    • Bamias, A.; Pignata, S.; Pujade-Lauraine, E. Angiogenesis: A promising therapeutic target for ovarian cancer. Crit. Rev. Oncol. Hematol. 2012, 84, 314-326.
    • (2012) Crit. Rev. Oncol. Hematol , vol.84 , pp. 314-326
    • Bamias, A.1    Pignata, S.2    Pujade-Lauraine, E.3
  • 40
    • 0033810455 scopus 로고    scopus 로고
    • Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells
    • Salcedo, R.; Resau, J.H.; Halverson, D.; Hudson, E.A.; Dambach, M.; Powell, D.; Wasserman, K.; Oppenheim, J.J. Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells. FASEB J. 2000, 14, 2055-2064.
    • (2000) FASEB J , vol.14 , pp. 2055-2064
    • Salcedo, R.1    Resau, J.H.2    Halverson, D.3    Hudson, E.A.4    Dambach, M.5    Powell, D.6    Wasserman, K.7    Oppenheim, J.J.8
  • 41
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • Coughlin, S.R. Thrombin signalling and protease-activated receptors. Nature 2000, 407, 258-264.
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 42
    • 77955022787 scopus 로고    scopus 로고
    • Identification of a metalloprotease-chemokine signaling system in the ovarian cancer microenvironment: Implications for antiangiogenic therapy
    • Agarwal, A.; Tressel, S.L.; Kaimal, R.; Balla, M.; Lam, F.H.; Covic, L.; Kuliopulos, A. Identification of a metalloprotease-chemokine signaling system in the ovarian cancer microenvironment: Implications for antiangiogenic therapy. Cancer Res. 2010, 70, 5880-5890.
    • (2010) Cancer Res , vol.70 , pp. 5880-5890
    • Agarwal, A.1    Tressel, S.L.2    Kaimal, R.3    Balla, M.4    Lam, F.H.5    Covic, L.6    Kuliopulos, A.7
  • 45
    • 77955117388 scopus 로고    scopus 로고
    • CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis
    • Yang, G.; Rosen, D.G.; Liu, G.; Yang, F.; Guo, X.; Xiao, X.; Xue, F.; Mercado-Uribe, I.; Huang, J.; Lin, S.H. et al. CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Clin. Cancer Res. 2010, 16, 3875-3886.
    • (2010) Clin. Cancer Res , vol.16 , pp. 3875-3886
    • Yang, G.1    Rosen, D.G.2    Liu, G.3    Yang, F.4    Guo, X.5    Xiao, X.6    Xue, F.7    Mercado-Uribe, I.8    Huang, J.9    Lin, S.H.10
  • 46
    • 19944431949 scopus 로고    scopus 로고
    • CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers
    • Kryczek, I.; Lange, A.; Mottram, P.; Alvarez, X.; Cheng, P.; Hogan, M.; Moons, L.; Wei, S.; Zou, L.; Machelon, V. et al. CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers. Cancer Res. 2005, 65, 465-472.
    • (2005) Cancer Res , vol.65 , pp. 465-472
    • Kryczek, I.1    Lange, A.2    Mottram, P.3    Alvarez, X.4    Cheng, P.5    Hogan, M.6    Moons, L.7    Wei, S.8    Zou, L.9    Machelon, V.10
  • 47
    • 80051690814 scopus 로고    scopus 로고
    • CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer
    • Righi, E.; Kashiwagi, S.; Yuan, J.; Santosuosso, M.; Leblanc, P.; Ingraham, R.; Forbes, B.; Edelblute, B.; Collette, B.; Xing, D. et al. CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer. Cancer Res. 2011, 71, 5522-5534.
    • (2011) Cancer Res , vol.71 , pp. 5522-5534
    • Righi, E.1    Kashiwagi, S.2    Yuan, J.3    Santosuosso, M.4    Leblanc, P.5    Ingraham, R.6    Forbes, B.7    Edelblute, B.8    Collette, B.9    Xing, D.10
  • 48
    • 33845966763 scopus 로고    scopus 로고
    • Eosinophilic granulocytes and damage-associated molecular pattern molecules (DAMPs, role in the inflammatory response within tumors
    • Lotfi, R.; Lee, J.J.; Lotze, M.T. Eosinophilic granulocytes and damage-associated molecular pattern molecules (DAMPs, role in the inflammatory response within tumors. J. Immunother. 2007, 30, 16-28.
    • (2007) J. Immunother , vol.30 , pp. 16-28
    • Lotfi, R.1    Lee, J.J.2    Lotze, M.T.3
  • 50
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi, S. Regulatory T cells: Key controllers of immunologic self-tolerance. Cell 2000, 101, 455-458.
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 51
    • 19944423801 scopus 로고    scopus 로고
    • Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers
    • Burleson, K.M.; Hansen, L.K.; Skubitz, A.P. Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers. Clin. Exp. Metastasis 2004, 21, 685-697.
    • (2004) Clin. Exp. Metastasis , vol.21 , pp. 685-697
    • Burleson, K.M.1    Hansen, L.K.2    Skubitz, A.P.3
  • 53
    • 84857849160 scopus 로고    scopus 로고
    • In vitro mesothelial clearance assay that models the early steps of ovarian cancer metastasis
    • doi:10.3791/3888
    • Davidowitz, R.A.; Iwanicki, M.P.; Brugge, J.S. In vitro mesothelial clearance assay that models the early steps of ovarian cancer metastasis. J. Vis. Exp. 2012, doi:10.3791/3888.
    • (2012) J. Vis. Exp
    • Davidowitz, R.A.1    Iwanicki, M.P.2    Brugge, J.S.3
  • 54
    • 84862908799 scopus 로고    scopus 로고
    • Fractalkine receptor CX(3)CR1 is expressed in epithelial ovarian carcinoma cells and required for motility and adhesion to peritoneal mesothelial cells
    • Kim, M.; Rooper, L.; Xie, J.; Kajdacsy-Balla, A.A.; Barbolina, M.V. Fractalkine receptor CX(3)CR1 is expressed in epithelial ovarian carcinoma cells and required for motility and adhesion to peritoneal mesothelial cells. Mol. Cancer Res. 2012, 10, 11-24.
    • (2012) Mol. Cancer Res , vol.10 , pp. 11-24
    • Kim, M.1    Rooper, L.2    Xie, J.3    Kajdacsy-Balla, A.A.4    Barbolina, M.V.5
  • 57
    • 84869223806 scopus 로고    scopus 로고
    • The lymphotactin receptor is expressed in epithelial ovarian carcinoma and contributes to cell migration and proliferation
    • Kim, M.; Rooper, L.; Xie, J.; Rayahin, J.; Burdette, J.E.; Kajdacsy-Balla, A.A.; Barbolina, M.V. The lymphotactin receptor is expressed in epithelial ovarian carcinoma and contributes to cell migration and proliferation. Mol. Cancer Res. 2012, 10, 1419-1429.
    • (2012) Mol. Cancer Res , vol.10 , pp. 1419-1429
    • Kim, M.1    Rooper, L.2    Xie, J.3    Rayahin, J.4    Burdette, J.E.5    Kajdacsy-Balla, A.A.6    Barbolina, M.V.7
  • 58
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce, J.A.; Pollard, J.W. Microenvironmental regulation of metastasis. Nat. Rev. Cancer 2009, 9, 239-252.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 59
    • 84884368877 scopus 로고    scopus 로고
    • Influence of tumour micro-environment heterogeneity on therapeutic response
    • Junttila, M.R.; de Sauvage, F.J. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 2013, 501, 346-354.
    • (2013) Nature , vol.501 , pp. 346-354
    • Junttila, M.R.1    de Sauvage, F.J.2
  • 60
    • 79955870488 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts and their putative role in potentiating the initiation and development of epithelial ovarian cancer
    • Schauer, I.G.; Sood, A.K.; Mok, S.; Liu, J. Cancer-associated fibroblasts and their putative role in potentiating the initiation and development of epithelial ovarian cancer. Neoplasia 2011, 13, 393-405.
    • (2011) Neoplasia , vol.13 , pp. 393-405
    • Schauer, I.G.1    Sood, A.K.2    Mok, S.3    Liu, J.4
  • 61
    • 84890055236 scopus 로고    scopus 로고
    • Cancer cell-derived lymphotoxin mediates reciprocal tumour-stromal interactions in human ovarian cancer by inducing CXCL11 in fibroblasts
    • Lau, T.S.; Chung, T.K.; Cheung, T.H.; Chan, L.K.; Cheung, L.W.; Yim, S.F.; Siu, N.S.; Lo, K.W.; Yu, M.M.; Kulbe, H. et al. Cancer cell-derived lymphotoxin mediates reciprocal tumour-stromal interactions in human ovarian cancer by inducing CXCL11 in fibroblasts. J. Pathol. 2013, 232, 43-56.
    • (2013) J. Pathol , vol.232 , pp. 43-56
    • Lau, T.S.1    Chung, T.K.2    Cheung, T.H.3    Chan, L.K.4    Cheung, L.W.5    Yim, S.F.6    Siu, N.S.7    Lo, K.W.8    Yu, M.M.9    Kulbe, H.10
  • 63
    • 84870510405 scopus 로고    scopus 로고
    • Sequential genetic change at the TP53 and chemokine receptor CXCR4 locus during transformation of human ovarian surface epithelium
    • Archibald, K.M.; Kulbe, H.; Kwong, J.; Chakravarty, P.; Temple, J.; Chaplin, T.; Flak, M.B.; McNeish, I.A.; Deen, S.; Brenton, J.D. et al. Sequential genetic change at the TP53 and chemokine receptor CXCR4 locus during transformation of human ovarian surface epithelium. Oncogene 2012, 31, 4987-4995.
    • (2012) Oncogene , vol.31 , pp. 4987-4995
    • Archibald, K.M.1    Kulbe, H.2    Kwong, J.3    Chakravarty, P.4    Temple, J.5    Chaplin, T.6    Flak, M.B.7    McNeish, I.A.8    Deen, S.9    Brenton, J.D.10
  • 64
    • 79958158656 scopus 로고    scopus 로고
    • Chemokine axes CXCL12/CXCR4 and CXCL16/CXCR6 correlate with lymph node metastasis in epithelial ovarian carcinoma
    • Guo, L.; Cui, Z.M.; Zhang, J.; Huang, Y. Chemokine axes CXCL12/CXCR4 and CXCL16/CXCR6 correlate with lymph node metastasis in epithelial ovarian carcinoma. Chin. J. Cancer 2011, 30, 336-343.
    • (2011) Chin. J. Cancer , vol.30 , pp. 336-343
    • Guo, L.1    Cui, Z.M.2    Zhang, J.3    Huang, Y.4
  • 65
    • 34548118196 scopus 로고    scopus 로고
    • The synergistic effects of CXCR4 and EGFR on promoting EGF-mediated metastasis in ovarian cancer cells
    • Guo, Z.; Cai, S.; Fang, R.; Chen, H.; Du, J.; Tan, Y.; Ma, W.; Hu, H.; Liu, Y. The synergistic effects of CXCR4 and EGFR on promoting EGF-mediated metastasis in ovarian cancer cells. Colloids Surf. B 2007, 60, 1-6.
    • (2007) Colloids Surf. B , vol.60 , pp. 1-6
    • Guo, Z.1    Cai, S.2    Fang, R.3    Chen, H.4    Du, J.5    Tan, Y.6    Ma, W.7    Hu, H.8    Liu, Y.9
  • 66
    • 0035393583 scopus 로고    scopus 로고
    • Epithelial cancer cell migration: A role for chemokine receptors?
    • Scotton, C.J.; Wilson, J.L.; Milliken, D.; Stamp, G.; Balkwill, F.R. Epithelial cancer cell migration: A role for chemokine receptors? Cancer Res. 2001, 61, 4961-4965.
    • (2001) Cancer Res , vol.61 , pp. 4961-4965
    • Scotton, C.J.1    Wilson, J.L.2    Milliken, D.3    Stamp, G.4    Balkwill, F.R.5
  • 67
    • 84863020036 scopus 로고    scopus 로고
    • Loss of breast cancer metastasis suppressor 1 promotes ovarian cancer cell metastasis by increasing chemokine receptor 4 expression
    • Sheng, X.J.; Zhou, Y.Q.; Song, Q.Y.; Zhou, D.M.; Liu, Q.C. Loss of breast cancer metastasis suppressor 1 promotes ovarian cancer cell metastasis by increasing chemokine receptor 4 expression. Oncol. Rep. 2012, 27, 1011-1018.
    • (2012) Oncol. Rep , vol.27 , pp. 1011-1018
    • Sheng, X.J.1    Zhou, Y.Q.2    Song, Q.Y.3    Zhou, D.M.4    Liu, Q.C.5
  • 68
    • 84879796776 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 (SDF-1) enhances cells invasion by αvβ6 integrin-mediated signaling in ovarian cancer
    • Xue, B.; Wu, W.; Huang, K.; Xie, T.; Xu, X.; Zhang, H.; Qi, C.; Ge, J.; Yu, Y. Stromal cell-derived factor-1 (SDF-1) enhances cells invasion by αvβ6 integrin-mediated signaling in ovarian cancer. Mol. Cell Biochem. 2013, 380, 177-184.
    • (2013) Mol. Cell Biochem , vol.380 , pp. 177-184
    • Xue, B.1    Wu, W.2    Huang, K.3    Xie, T.4    Xu, X.5    Zhang, H.6    Qi, C.7    Ge, J.8    Yu, Y.9
  • 72
    • 84866640259 scopus 로고    scopus 로고
    • Autocrine CCL5 signaling promotes invasion and migration of CD133+ ovarian cancer stem-like cells via NF-κB-mediated MMP-9 upregulation
    • Long, H.; Xie, R.; Xiang, T.; Zhao, Z.; Lin, S.; Liang, Z.; Chen, Z.; Zhu, B. Autocrine CCL5 signaling promotes invasion and migration of CD133+ ovarian cancer stem-like cells via NF-κB-mediated MMP-9 upregulation. Stem Cells 2012, 30, 2309-2319.
    • (2012) Stem Cells , vol.30 , pp. 2309-2319
    • Long, H.1    Xie, R.2    Xiang, T.3    Zhao, Z.4    Lin, S.5    Liang, Z.6    Chen, Z.7    Zhu, B.8
  • 73
    • 36749003738 scopus 로고    scopus 로고
    • Involvement of SDF-1alpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma
    • Kajiyama, H.; Shibata, K.; Terauchi, M.; Ino, K.; Nawa, A.; Kikkawa, F. Involvement of SDF-1alpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma. Int. J. Cancer 2008, 122, 91-99.
    • (2008) Int. J. Cancer , vol.122 , pp. 91-99
    • Kajiyama, H.1    Shibata, K.2    Terauchi, M.3    Ino, K.4    Nawa, A.5    Kikkawa, F.6
  • 74
    • 67651176019 scopus 로고    scopus 로고
    • An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells
    • Kwong, J.; Kulbe, H.; Wong, D.; Chakravarty, P.; Balkwill, F. An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells. Mol. Cancer Ther. 2009, 8, 1893-1905.
    • (2009) Mol. Cancer Ther , vol.8 , pp. 1893-1905
    • Kwong, J.1    Kulbe, H.2    Wong, D.3    Chakravarty, P.4    Balkwill, F.5
  • 78
    • 79952281752 scopus 로고    scopus 로고
    • Tumor immune surveillance and ovarian cancer: Lessons on immune mediated tumor rejection or tolerance
    • Kandalaft, L.E.; Motz, G.T.; Duraiswamy, J.; Coukos, G. Tumor immune surveillance and ovarian cancer: Lessons on immune mediated tumor rejection or tolerance. Cancer Metastasis Rev. 2011, 30, 141-151.
    • (2011) Cancer Metastasis Rev , vol.30 , pp. 141-151
    • Kandalaft, L.E.1    Motz, G.T.2    Duraiswamy, J.3    Coukos, G.4
  • 79
    • 84865698086 scopus 로고    scopus 로고
    • Double agents in the war on cancer: Leukocytes govern ovarian cancer progression
    • Scarlett, U.K. and J.R. Conejo-Garcia, Double agents in the war on cancer: Leukocytes govern ovarian cancer progression. Oncotarget 2012, 3, 226-227.
    • (2012) Oncotarget , vol.3 , pp. 226-227
    • Scarlett, U.K.1    Conejo-Garcia, J.R.2
  • 80
    • 0041431005 scopus 로고    scopus 로고
    • Immunologic principles and immunotherapeutic approaches in ovarian cancer
    • Knutson, K.L.; Curiel, T.J.; Salazar, L.; Disis, M.L. Immunologic principles and immunotherapeutic approaches in ovarian cancer. Hematol. Oncol. Clin. N. Am. 2003, 17, 1051-1073.
    • (2003) Hematol. Oncol. Clin. N. Am , vol.17 , pp. 1051-1073
    • Knutson, K.L.1    Curiel, T.J.2    Salazar, L.3    Disis, M.L.4
  • 82
    • 77950189167 scopus 로고    scopus 로고
    • Ovarian cancer creates a suppressive microenvironment to escape immune elimination
    • Yigit, R.; Massuger, L.F.; Figdor, C.G.; Torensma, R. Ovarian cancer creates a suppressive microenvironment to escape immune elimination. Gynecol. Oncol. 2010, 117, 366-372.
    • (2010) Gynecol. Oncol , vol.117 , pp. 366-372
    • Yigit, R.1    Massuger, L.F.2    Figdor, C.G.3    Torensma, R.4
  • 83
    • 84872872011 scopus 로고    scopus 로고
    • Dynamics of T-cell infiltration during the course of ovarian cancer: The gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells
    • Fialová, A.; Partlová, S.; Sojka, L.; Hromádková, H.; Brtnický, T.; Fučíková, J.; Kocián, P.; Rob, L.; Bartůňková, J.; Spíšek, R. Dynamics of T-cell infiltration during the course of ovarian cancer: The gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells. Int. J. Cancer 2013, 132, 1070-1079.
    • (2013) Int. J. Cancer , vol.132 , pp. 1070-1079
    • Fialová, A.1    Partlová, S.2    Sojka, L.3    Hromádková, H.4    Brtnický, T.5    Fučíková, J.6    Kocián, P.7    Rob, L.8    Bartůňková, J.9    Spíšek, R.10
  • 85
    • 84865747539 scopus 로고    scopus 로고
    • CXCR3+ T regulatory cells selectively accumulate in human ovarian carcinomas to limit type I immunity
    • Redjimi, N.; Raffin, C.; Raimbaud, I.; Pignon, P.; Matsuzaki, J.; Odunsi, K.; Valmori, D.; Ayyoub, M. CXCR3+ T regulatory cells selectively accumulate in human ovarian carcinomas to limit type I immunity. Cancer Res. 2012, 72, 4351-4360.
    • (2012) Cancer Res , vol.72 , pp. 4351-4360
    • Redjimi, N.1    Raffin, C.2    Raimbaud, I.3    Pignon, P.4    Matsuzaki, J.5    Odunsi, K.6    Valmori, D.7    Ayyoub, M.8
  • 86
  • 87
    • 0030198856 scopus 로고    scopus 로고
    • A cytokine profile of normal and malignant ovary
    • Burke, F.; Relf, M.; Negus, R.; Balkwill, F. A cytokine profile of normal and malignant ovary. Cytokine 1996, 8, 578-585.
    • (1996) Cytokine , vol.8 , pp. 578-585
    • Burke, F.1    Relf, M.2    Negus, R.3    Balkwill, F.4
  • 89
    • 0034650329 scopus 로고    scopus 로고
    • Defective expression of the monocyte chemotactic protein-1 receptor CCR2 in macrophages associated with human ovarian carcinoma
    • Sica, A.; Saccani, A.; Bottazzi, B.; Bernasconi, S.; Allavena, P.; Gaetano, B.; Fei, F.; LaRosa, G.; Scotton, C.; Balkwill, F. et al. Defective expression of the monocyte chemotactic protein-1 receptor CCR2 in macrophages associated with human ovarian carcinoma. J. Immunol. 2000, 164, 733-738.
    • (2000) J. Immunol , vol.164 , pp. 733-738
    • Sica, A.1    Saccani, A.2    Bottazzi, B.3    Bernasconi, S.4    Allavena, P.5    Gaetano, B.6    Fei, F.7    Larosa, G.8    Scotton, C.9    Balkwill, F.10
  • 91
    • 0141431027 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha: A potential target for the therapy of solid tumours
    • Szlosarek, P.W.; Balkwill, F.R. Tumour necrosis factor alpha: A potential target for the therapy of solid tumours. Lancet Oncol. 2003, 4, 565-573.
    • (2003) Lancet Oncol , vol.4 , pp. 565-573
    • Szlosarek, P.W.1    Balkwill, F.R.2
  • 92
    • 28544436109 scopus 로고    scopus 로고
    • The inflammatory cytokine tumor necrosis factor-alpha regulates chemokine receptor expression on ovarian cancer cells
    • Kulbe, H.; Hagemann, T.; Szlosarek, P.W.; Balkwill, F.R.; Wilson, J.L. The inflammatory cytokine tumor necrosis factor-alpha regulates chemokine receptor expression on ovarian cancer cells. Cancer Res. 2005, 65, 10355-10362.
    • (2005) Cancer Res , vol.65 , pp. 10355-10362
    • Kulbe, H.1    Hagemann, T.2    Szlosarek, P.W.3    Balkwill, F.R.4    Wilson, J.L.5
  • 93
    • 84255170450 scopus 로고    scopus 로고
    • PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment
    • Obermajer, N.; Muthuswamy, R.; Odunsi, K.; Edwards, R.P.; Kalinski, P. PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment. Cancer Res. 2011, 71, 7463-7470.
    • (2011) Cancer Res , vol.71 , pp. 7463-7470
    • Obermajer, N.1    Muthuswamy, R.2    Odunsi, K.3    Edwards, R.P.4    Kalinski, P.5
  • 95
    • 66449117956 scopus 로고    scopus 로고
    • Phenotypic and functional delineation of murine CX(3)CR1 monocyte-derived cells in ovarian cancer
    • 1 p following 573
    • Hart, K.M.; Bak, S.P.; Alonso, A.; Berwin, B. Phenotypic and functional delineation of murine CX(3)CR1 monocyte-derived cells in ovarian cancer. Neoplasia 2009, 11, 564-573, 1 p following 573.
    • (2009) Neoplasia , vol.11 , pp. 564-573
    • Hart, K.M.1    Bak, S.P.2    Alonso, A.3    Berwin, B.4
  • 96
    • 84881450889 scopus 로고    scopus 로고
    • IL-18-primed helper NK cells collaborate with dendritic cells to promote recruitment of effector CD8+ T cells to the tumor microenvironment
    • Wong, J.L.; Berk, E.; Edwards, R.P.; Kalinski, P. IL-18-primed helper NK cells collaborate with dendritic cells to promote recruitment of effector CD8+ T cells to the tumor microenvironment. Cancer Res. 2013, 73, 4653-4662.
    • (2013) Cancer Res , vol.73 , pp. 4653-4662
    • Wong, J.L.1    Berk, E.2    Edwards, R.P.3    Kalinski, P.4
  • 97
    • 68049118835 scopus 로고    scopus 로고
    • CCL5-mediated endogenous antitumor immunity elicited by adoptively transferred lymphocytes and dendritic cell depletion
    • Nesbeth, Y.; Scarlett, U.; Cubillos-Ruiz, J.; Martinez, D.; Engle, X.; Turk, M.J.; Conejo-Garcia, J.R. CCL5-mediated endogenous antitumor immunity elicited by adoptively transferred lymphocytes and dendritic cell depletion. Cancer Res. 2009, 69, 6331-6338.
    • (2009) Cancer Res , vol.69 , pp. 6331-6338
    • Nesbeth, Y.1    Scarlett, U.2    Cubillos-Ruiz, J.3    Martinez, D.4    Engle, X.5    Turk, M.J.6    Conejo-Garcia, J.R.7
  • 98
    • 84860485283 scopus 로고    scopus 로고
    • Molecular mechanisms of pancreatic cancer dissemination: The role of the chemokine system
    • Marchesi, F.; Grizzi, F.; Laghi, L.; Mantovani, A.; Allavena, P. Molecular mechanisms of pancreatic cancer dissemination: The role of the chemokine system. Curr. Pharm. Des. 2012, 18, 2432-2438.
    • (2012) Curr. Pharm. Des , vol.18 , pp. 2432-2438
    • Marchesi, F.1    Grizzi, F.2    Laghi, L.3    Mantovani, A.4    Allavena, P.5
  • 99
    • 0033012398 scopus 로고    scopus 로고
    • Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
    • Berger, E.A.; Murphy, P.M.; Farber, J.M. Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 1999, 17, 657-700.
    • (1999) Annu. Rev. Immunol , vol.17 , pp. 657-700
    • Berger, E.A.1    Murphy, P.M.2    Farber, J.M.3
  • 100
    • 0032693101 scopus 로고    scopus 로고
    • Chemokines and renal inflammation
    • Panzer, U.; Stahl, R.A. Chemokines and renal inflammation. Nephrologie 1999, 20, 335-341.
    • (1999) Nephrologie , vol.20 , pp. 335-341
    • Panzer, U.1    Stahl, R.A.2
  • 101
    • 0033652283 scopus 로고    scopus 로고
    • The strategy of blocking the chemokine system to combat disease
    • Proudfoot, A.E.; Power, C.A.; Wells, T.N. The strategy of blocking the chemokine system to combat disease. Immunol. Rev. 2000, 177, 246-256.
    • (2000) Immunol. Rev , vol.177 , pp. 246-256
    • Proudfoot, A.E.1    Power, C.A.2    Wells, T.N.3
  • 103
    • 33644883892 scopus 로고    scopus 로고
    • Asthma, allergy and chemokines
    • Pease, J.E. Asthma, allergy and chemokines. Curr. Drug Targets 2006, 7, 3-12.
    • (2006) Curr. Drug Targets , vol.7 , pp. 3-12
    • Pease, J.E.1
  • 104
    • 33751249635 scopus 로고    scopus 로고
    • The chemokine network: A target in cancer biology?
    • Slettenaar, V.I.; Wilson, J.L. The chemokine network: A target in cancer biology? Adv. Drug Deliv. Rev. 2006, 58, 962-974.
    • (2006) Adv. Drug Deliv. Rev , vol.58 , pp. 962-974
    • Slettenaar, V.I.1    Wilson, J.L.2
  • 105
    • 0031694532 scopus 로고    scopus 로고
    • Definition, function and pathophysiological significance of chemokine receptors
    • Wells, T.N.; Power, C.A.; Proudfoot, A.E. Definition, function and pathophysiological significance of chemokine receptors. Trends Pharmacol. Sci. 1998, 19, 376-380.
    • (1998) Trends Pharmacol. Sci , vol.19 , pp. 376-380
    • Wells, T.N.1    Power, C.A.2    Proudfoot, A.E.3
  • 106
    • 84869994291 scopus 로고    scopus 로고
    • Chemokine receptor antagonists
    • Pease, J.; Horuk, R. Chemokine receptor antagonists. J. Med. Chem. 2012, 55, 9363-9392.
    • (2012) J. Med. Chem , vol.55 , pp. 9363-9392
    • Pease, J.1    Horuk, R.2
  • 107
    • 46349097362 scopus 로고    scopus 로고
    • Reviews of anti-infective agents: Maraviroc: The first of a new class of antiretroviral agents
    • MacArthur, R.D.; Novak, R.M. Reviews of anti-infective agents: Maraviroc: The first of a new class of antiretroviral agents. Clin. Infect. Dis. 2008, 47, 236-241.
    • (2008) Clin. Infect. Dis , vol.47 , pp. 236-241
    • Macarthur, R.D.1    Novak, R.M.2
  • 108
    • 64249173226 scopus 로고    scopus 로고
    • The AMD3100 story: The path to the discovery of a stem cell mobilizer (Mozobil)
    • De Clercq, E. The AMD3100 story: The path to the discovery of a stem cell mobilizer (Mozobil). Biochem. Pharmacol. 2009, 77, 1655-1664.
    • (2009) Biochem. Pharmacol , vol.77 , pp. 1655-1664
    • de Clercq, E.1
  • 109
    • 77953125223 scopus 로고    scopus 로고
    • FDA review summary: Mozobil in combination with granulocyte colony-stimulating factor to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation
    • Brave, M.; Farrell, A.; Ching Lin, S.; Ocheltree, T.; Pope Miksinski, S.; Lee, S.L.; Saber, H.; Fourie, J.; Tornoe, C.; Booth, B. et al. FDA review summary: Mozobil in combination with granulocyte colony-stimulating factor to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation. Oncology 2010, 78, 282-288.
    • (2010) Oncology , vol.78 , pp. 282-288
    • Brave, M.1    Farrell, A.2    Ching, L.S.3    Ocheltree, T.4    Pope, M.S.5    Lee, S.L.6    Saber, H.7    Fourie, J.8    Tornoe, C.9    Booth, B.10


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