Autocrine CCL5 signaling promotes invasion and migration of CD133 + ovarian cancer stem-like cells via NF-κB-mediated MMP-9 upregulation

Stem Cells

Volumn 30, Issue 10, 2012, Pages 2309-2319

  Long, Haixia ^a   Xie, Rongkai ^a   Xiang, Tong ^a   Zhao, Zhongquan ^a   Lin, Sheng ^a   Liang, Zhiqing ^a   Chen, Zhengtang ^a   Zhu, Bo ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cancer stem cells; CCL5; Invasion; Migration; Ovarian

Indexed keywords

CD133 ANTIGEN; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RANTES;

ANIMAL EXPERIMENT; ARTICLE; CANCER STEM CELL; CANCER STEM LIKE CELL; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OVARY CANCER; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UPREGULATION;

ANTIGENS, CD; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CCL5; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; NF-KAPPA B; OVARIAN NEOPLASMS; OVARY; PEPTIDES; PRIMARY CELL CULTURE; RECEPTORS, CCR1; RECEPTORS, CCR3; RECEPTORS, CCR5; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL;

EID: 84866640259     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1194     Document Type: Article

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