메뉴 건너뛰기




Volumn 8, Issue 5, 2010, Pages 653-664

Microenvironmental regulation of chemokine (C-X-C-Motif) receptor 4 in ovarian carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CHEMOKINE RECEPTOR CXCR4; COLLAGEN TYPE 1; I KAPPA B KINASE BETA; COLLAGEN; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; SMALL INTERFERING RNA; STROMAL CELL DERIVED FACTOR 1;

EID: 77952932498     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-09-0463     Document Type: Article
Times cited : (49)

References (52)
  • 2
    • 0027382941 scopus 로고
    • Cancer of the ovary
    • [see comment]. Erratum in: N Engl J Med 1994;330:448
    • Cannistra SA. Cancer of the ovary [see comment]. N Engl J Med 1993;329:1550-9. Erratum in: N Engl J Med 1994;330:448.
    • (1993) N Engl J Med , vol.329 , pp. 1550-1559
    • Cannistra, S.A.1
  • 3
    • 0035138697 scopus 로고    scopus 로고
    • CD44 and β1 integrins mediate ovarian carcinoma cell migration toward extracellular matrix proteins
    • Casey RC, Skubitz AP. CD44 and β1 integrins mediate ovarian carcinoma cell migration toward extracellular matrix proteins. Clin Exp Metastasis 2000;18:67-75.
    • (2000) Clin Exp Metastasis , vol.18 , pp. 67-75
    • Casey, R.C.1    Skubitz, A.P.2
  • 4
    • 0032588952 scopus 로고    scopus 로고
    • CD44 and β1 integrin mediate ovarian carcinoma cell adhesion to peritoneal mesothelial cells
    • Lessan K, Aguiar DJ, Oegema T, Siebenson L, Skubitz AP. CD44 and β1 integrin mediate ovarian carcinoma cell adhesion to peritoneal mesothelial cells. Am J Pathol 1999;154:1525-1537
    • (1999) Am J Pathol , vol.154 , pp. 1525-1537
    • Lessan, K.1    Aguiar, D.J.2    Oegema, T.3    Siebenson, L.4    Skubitz, A.P.5
  • 5
    • 44349097371 scopus 로고    scopus 로고
    • Motility-related actinin α-4 is associated with advanced and metastatic ovarian carcinoma
    • Barbolina M, Adley BP, Kelly DL, et al. Motility-related actinin α-4 is associated with advanced and metastatic ovarian carcinoma. Lab Invest 2008;88:602-614
    • (2008) Lab Invest , vol.88 , pp. 602-614
    • Barbolina, M.1    Adley, B.P.2    Kelly, D.L.3
  • 6
    • 41149133988 scopus 로고    scopus 로고
    • Wilms tumor gene protein 1 is associated with ovarian cancer metastasis and modulates cell invasion
    • Barbolina MV, Adley BP, Shea LD, Stack MS. Wilms tumor gene protein 1 is associated with ovarian cancer metastasis and modulates cell invasion. Cancer 2008;112:1632-1641
    • (2008) Cancer , vol.112 , pp. 1632-1641
    • Barbolina, M.V.1    Adley, B.P.2    Shea, L.D.3    Stack, M.S.4
  • 7
    • 33947518899 scopus 로고    scopus 로고
    • Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression
    • Barbolina MV, Adley BP, Ariztia EV, Liu Y, Stack MS. Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression. J Biol Chem 2007;282:4924-4931
    • (2007) J Biol Chem , vol.282 , pp. 4924-4931
    • Barbolina, M.V.1    Adley, B.P.2    Ariztia, E.V.3    Liu, Y.4    Stack, M.S.5
  • 8
    • 0030002637 scopus 로고    scopus 로고
    • HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
    • see comment
    • Feng Y, Broder CC, Kennedy PE, Berger EA. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor [see comment]. Science 1996;272:872-877
    • (1996) Science , vol.272 , pp. 872-877
    • Feng, Y.1    Broder, C.C.2    Kennedy, P.E.3    Berger, E.A.4
  • 9
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F. Cancer and the chemokine network. Nat Rev Cancer 2004;4:540-550
    • (2004) Nat Rev Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 10
    • 33746868899 scopus 로고    scopus 로고
    • Functions of CXCL12 and CXCR4 in breast cancer
    • Luker KE, Luker GD. Functions of CXCL12 and CXCR4 in breast cancer. Cancer Lett 2006;238:30-41.
    • (2006) Cancer Lett , vol.238 , pp. 30-41
    • Luker, K.E.1    Luker, G.D.2
  • 11
    • 33746086397 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in organ-specific metastasis
    • Zlotnik A. Involvement of chemokine receptors in organ-specific metastasis. Contrib Microbiol 2006;13:191-199
    • (2006) Contrib Microbiol , vol.13 , pp. 191-199
    • Zlotnik, A.1
  • 12
    • 33344464945 scopus 로고    scopus 로고
    • CXCR4: A key receptor in the crosstalk between tumor cells and their microenvironment
    • Burger JA, Kipps TJ. CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 2006;107:1761-1767
    • (2006) Blood , vol.107 , pp. 1761-1767
    • Burger, J.A.1    Kipps, T.J.2
  • 13
    • 34748820033 scopus 로고    scopus 로고
    • Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response
    • Koizumi K, Hojo S, Akashi T, Yasumoto K, Saiki I. Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response. Cancer Sci 2007;98:1652-1658
    • (2007) Cancer Sci , vol.98 , pp. 1652-1658
    • Koizumi, K.1    Hojo, S.2    Akashi, T.3    Yasumoto, K.4    Saiki, I.5
  • 14
    • 0038666134 scopus 로고    scopus 로고
    • Role of the α-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system
    • Lazarini F, Tham TN, Casanova P, Arenzana-Seisdedos F, Dubois-Dalcq M. Role of the α-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system. Glia 2003;42:139-148
    • (2003) Glia , vol.42 , pp. 139-148
    • Lazarini, F.1    Tham, T.N.2    Casanova, P.3    Arenzana-Seisdedos, F.4    Dubois-Dalcq, M.5
  • 15
    • 34248220063 scopus 로고    scopus 로고
    • CXC chemokine receptor 4 regulates neuronal migration and axonal pathfinding in the developing nervous system: Implications for neuronal regeneration in the adult brain
    • Stumm R, Hollt V. CXC chemokine receptor 4 regulates neuronal migration and axonal pathfinding in the developing nervous system: implications for neuronal regeneration in the adult brain. J Mol Endocrinol 2007;38:377-382
    • (2007) J Mol Endocrinol , vol.38 , pp. 377-382
    • Stumm, R.1    Hollt, V.2
  • 17
    • 34547766462 scopus 로고    scopus 로고
    • Role of CXCL12 in metastasis of human ovarian cancer
    • Jiang YP, Wu XH, Xing HY, Du XY. Role of CXCL12 in metastasis of human ovarian cancer. Chin Med J 2007;120:1251-1255
    • (2007) Chin Med J , vol.120 , pp. 1251-1255
    • Jiang, Y.P.1    Wu, X.H.2    Xing, H.Y.3    Du, X.Y.4
  • 18
    • 0037108923 scopus 로고    scopus 로고
    • Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer
    • Scotton CJ, Wilson JL, Scott K, et al. Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer. Cancer Res 2002;62:5930-5938
    • (2002) Cancer Res , vol.62 , pp. 5930-5938
    • Scotton, C.J.1    Wilson, J.L.2    Scott, K.3
  • 19
    • 36749003738 scopus 로고    scopus 로고
    • Involvement of SDF-1α/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma
    • Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F. Involvement of SDF-1α/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma. Int J Cancer 2008;122:91-99
    • (2008) Int J Cancer , vol.122 , pp. 91-99
    • Kajiyama, H.1    Shibata, K.2    Terauchi, M.3    Ino, K.4    Nawa, A.5    Kikkawa, F.6
  • 20
    • 0038681342 scopus 로고    scopus 로고
    • The bicyclam AMD3100 story
    • De Clercq E. The bicyclam AMD3100 story. Nat Rev Drug Discov 2003;2:581-587
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 581-587
    • De Clercq, E.1
  • 21
    • 0029741632 scopus 로고    scopus 로고
    • Evidence for preferential adhesion of ovarian epithelial carcinoma cells to type I collagen mediated by the α2β1 integrin
    • Moser TL, Pizzo SV, Bafetti LM, Fishman DA, Stack MS. Evidence for preferential adhesion of ovarian epithelial carcinoma cells to type I collagen mediated by the α2β1 integrin. Int J Cancer 1996;67:695-701.
    • (1996) Int J Cancer , vol.67 , pp. 695-701
    • Moser, T.L.1    Pizzo, S.V.2    Bafetti, L.M.3    Fishman, D.A.4    Stack, M.S.5
  • 22
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A, Gupta PB, Sgroi DC, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005;121:335-348
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3
  • 23
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔ C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔ C(T)) method. Methods 2001;25:402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 25
    • 0035816605 scopus 로고    scopus 로고
    • Functional interplay between type I collagen and cell surface matrix metalloproteinase activity
    • Ellerbroek SM, Wu YI, Overall CM, Stack MS. Functional interplay between type I collagen and cell surface matrix metalloproteinase activity. J Biol Chem 2001;276:24833-24842
    • (2001) J Biol Chem , vol.276 , pp. 24833-24842
    • Ellerbroek, S.M.1    Wu, Y.I.2    Overall, C.M.3    Stack, M.S.4
  • 26
    • 0033119050 scopus 로고    scopus 로고
    • Ovarian carcinoma regulation of matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase through β1 integrin
    • Ellerbroek SM, Fishman DA, Kearns AS, Bafetti LM, Stack MS. Ovarian carcinoma regulation of matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase through β1 integrin. Cancer Res 1999;59:1635-1641
    • (1999) Cancer Res , vol.59 , pp. 1635-1641
    • Ellerbroek, S.M.1    Fishman, D.A.2    Kearns, A.S.3    Bafetti, L.M.4    Stack, M.S.5
  • 27
    • 0035941359 scopus 로고    scopus 로고
    • Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1
    • McQuibban GA, Butler GS, Gong JH, et al. Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1. J Biol Chem 2001;276:43503-43508
    • (2001) J Biol Chem , vol.276 , pp. 43503-43508
    • McQuibban, G.A.1    Butler, G.S.2    Gong, J.H.3
  • 28
    • 67650097016 scopus 로고    scopus 로고
    • Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion
    • Barbolina MV, Adley BP, Kelly DL, et al. Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion. Int J Cancer 2009;125:816-825
    • (2009) Int J Cancer , vol.125 , pp. 816-825
    • Barbolina, M.V.1    Adley, B.P.2    Kelly, D.L.3
  • 29
    • 0038498102 scopus 로고    scopus 로고
    • NF-κB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4
    • HelbigG, ChristophersonKWII,Bhat-Nakshatri P, et al.NF-κB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J Biol Chem 2003;278:21631-21638
    • (2003) J Biol Chem , vol.278 , pp. 21631-21638
    • Helbig, G.1    Christopherson, K.2    Bhat-Nakshatri, P.3
  • 30
    • 36049020021 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-κB-dependent pathway in human lung cancer cells
    • Huang YC, Hsiao YC, Chen YJ, Wei YY, Lai TH, Tang CH. Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-κB-dependent pathway in human lung cancer cells. Biochem Pharmacol 2007;74:1702-1712
    • (2007) Biochem Pharmacol , vol.74 , pp. 1702-1712
    • Huang, Y.C.1    Hsiao, Y.C.2    Chen, Y.J.3    Wei, Y.Y.4    Lai, T.H.5    Tang, C.H.6
  • 31
    • 27544494623 scopus 로고    scopus 로고
    • Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1α (CXCL12) increases endothelial adhesion and transendothelial migration: Role of MEK/ERK signaling pathway-dependent NF-κB activation
    • Kukreja P, Abdel-Mageed AB, Mondal D, Liu K, Agrawal KC. Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1α (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-κB activation. Cancer Res 2005;65:9891-9898
    • (2005) Cancer Res , vol.65 , pp. 9891-9898
    • Kukreja, P.1    Abdel-Mageed, A.B.2    Mondal, D.3    Liu, K.4    Agrawal, K.C.5
  • 32
    • 0033596120 scopus 로고    scopus 로고
    • Regulation of DNA binding by Rel/NF-κB transcription factors: Structural views
    • Chen FE, Ghosh G. Regulation of DNA binding by Rel/NF-κB transcription factors: structural views. Oncogene 1999;18:6845-6852
    • (1999) Oncogene , vol.18 , pp. 6845-6852
    • Chen, F.E.1    Ghosh, G.2
  • 33
    • 0027248518 scopus 로고
    • Identification of a regulatory region of integrin-β-1 subunit using activating and inhibiting antibodies
    • Takada Y, Puzon W. Identification of a regulatory region of integrin-β-1 subunit using activating and inhibiting antibodies. J Biol Chem 1993;268:17597-17601
    • (1993) J Biol Chem , vol.268 , pp. 17597-17601
    • Takada, Y.1    Puzon, W.2
  • 34
    • 33644827993 scopus 로고    scopus 로고
    • CXCL12 overexpression and secretion by aging fibroblasts enhance human prostate epithelial proliferation in vitro
    • Begley L, Monteleon C, Shah RB, Macdonald JW, Macoska JA. CXCL12 overexpression and secretion by aging fibroblasts enhance human prostate epithelial proliferation in vitro. Aging Cell 2005;4:291-298
    • (2005) Aging Cell , vol.4 , pp. 291-298
    • Begley, L.1    Monteleon, C.2    Shah, R.B.3    Macdonald, J.W.4    Macoska, J.A.5
  • 35
    • 0141996919 scopus 로고    scopus 로고
    • Platelet chemokines and chemokine receptors: Linking hemostasis, inflammation, and host defense
    • Gear AR, Camerini D. Platelet chemokines and chemokine receptors: linking hemostasis, inflammation, and host defense. Microcirculation 2003;10:335-350
    • (2003) Microcirculation , vol.10 , pp. 335-350
    • Gear, A.R.1    Camerini, D.2
  • 36
    • 0035860149 scopus 로고    scopus 로고
    • Analysis of CC chemokine and chemokine receptor expression in solid ovarian tumours
    • Scotton C, Milliken D, Wilson J, Raju S, Balkwill F. Analysis of CC chemokine and chemokine receptor expression in solid ovarian tumours. Br J Cancer 2001;85:891-897
    • (2001) Br J Cancer , vol.85 , pp. 891-897
    • Scotton, C.1    Milliken, D.2    Wilson, J.3    Raju, S.4    Balkwill, F.5
  • 37
    • 33748548126 scopus 로고    scopus 로고
    • Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: An independent prognostic factor for tumor progression
    • Jiang YP, Wu XH, Shi B, Wu WX, Yin GR. Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: an independent prognostic factor for tumor progression. Gynecol Oncol 2006;103:226-233
    • (2006) Gynecol Oncol , vol.103 , pp. 226-233
    • Jiang, Y.P.1    Wu, X.H.2    Shi, B.3    Wu, W.X.4    Yin, G.R.5
  • 38
    • 0035371351 scopus 로고    scopus 로고
    • Type I collagen stabilization of matrix metalloproteinase-2
    • Ellerbroek SM, Wu YI, Stack MS. Type I collagen stabilization of matrix metalloproteinase-2. Arch Biochem Biophys 2001;390:51-56
    • (2001) Arch Biochem Biophys , vol.390 , pp. 51-56
    • Ellerbroek, S.M.1    Wu, Y.I.2    Stack, M.S.3
  • 39
    • 33846544434 scopus 로고    scopus 로고
    • Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer
    • Kodama J, Kusumoto T, et al. Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer. Ann Oncol 2007;18:70-76
    • (2007) Ann Oncol , vol.18 , pp. 70-76
    • Kodama, J.1    Kusumoto, T.2
  • 40
    • 0035282610 scopus 로고    scopus 로고
    • An attractive force in metastasis
    • comment
    • Liotta LA. An attractive force in metastasis [comment]. Nature 2001;410:24-25
    • (2001) Nature , vol.410 , pp. 24-25
    • Liotta, L.A.1
  • 41
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • see comment
    • Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis [see comment]. Nature 2001;410:50-56
    • (2001) Nature , vol.410 , pp. 50-56
    • Muller, A.1    Homey, B.2    Soto, H.3
  • 42
    • 33644546367 scopus 로고    scopus 로고
    • Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer
    • Erratum in: Cancer Res 2006;66:3957
    • Yasumoto K, Koizumi K, Kawashima A, et al. Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer. Cancer Res 2006;66:2181-7. Erratum in: Cancer Res 2006;66:3957.
    • (2006) Cancer Res , vol.66 , pp. 2181-2187
    • Yasumoto, K.1    Koizumi, K.2    Kawashima, A.3
  • 43
    • 35348829769 scopus 로고    scopus 로고
    • Up-regulation of CXC chemokines and their receptors: Implications for proinflammatory microenvironments of ovarian carcinomas and endometriosis
    • Furuya M, Suyama T, Usui H, et al. Up-regulation of CXC chemokines and their receptors: implications for proinflammatory microenvironments of ovarian carcinomas and endometriosis. Hum Pathol 2007;38:1676-1687
    • (2007) Hum Pathol , vol.38 , pp. 1676-1687
    • Furuya, M.1    Suyama, T.2    Usui, H.3
  • 44
    • 34249910655 scopus 로고    scopus 로고
    • Prognostic implications of the nuclear localization of Y-box-binding protein-1 and CXCR4 expression in ovarian cancer: Their correlation with activated Akt, LRP/MVP and P-glycoprotein expression
    • Oda Y, Ohishi Y, Basaki Y, et al. Prognostic implications of the nuclear localization of Y-box-binding protein-1 and CXCR4 expression in ovarian cancer: their correlation with activated Akt, LRP/MVP and P-glycoprotein expression. Cancer Sci 2007;98:1020-1026
    • (2007) Cancer Sci , vol.98 , pp. 1020-1026
    • Oda, Y.1    Ohishi, Y.2    Basaki, Y.3
  • 45
    • 59649111561 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 and the metalloproteinase MT1-MMP are mutually required during melanoma metastasis to lungs
    • Bartolome RA, Ferreiro S, Miquilena-Colina ME, et al. The chemokine receptor CXCR4 and the metalloproteinase MT1-MMP are mutually required during melanoma metastasis to lungs. Am J Pathol 2009; 174:602-612
    • (2009) Am J Pathol , vol.174 , pp. 602-612
    • Bartolome, R.A.1    Ferreiro, S.2    Miquilena-Colina, M.E.3
  • 46
    • 1942442183 scopus 로고    scopus 로고
    • Stromal cell-derived factor- 1 β promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities
    • Bartolome RA, Galvez BG, Longo N, et al. Stromal cell-derived factor- 1 β promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities. Cancer Res 2004;64:2534-2543
    • (2004) Cancer Res , vol.64 , pp. 2534-2543
    • Bartolome, R.A.1    Galvez, B.G.2    Longo, N.3
  • 47
    • 0034016785 scopus 로고    scopus 로고
    • Binding of stromal derived factor-1α (SDF-1α) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/threonine kinase AKT
    • Majka M, Ratajczak J, Kowalska MA, Ratajczak MZ. Binding of stromal derived factor-1α (SDF-1α) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/threonine kinase AKT. Eur J Haematol 2000;64:164-172
    • (2000) Eur J Haematol , vol.64 , pp. 164-172
    • Majka, M.1    Ratajczak, J.2    Kowalska, M.A.3    Ratajczak, M.Z.4
  • 48
    • 34249063875 scopus 로고    scopus 로고
    • Membrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells
    • Sroka IC, Nagle RB, Bowden GT. Membrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells. Neoplasia 2007;9:406-417
    • (2007) Neoplasia , vol.9 , pp. 406-417
    • Sroka, I.C.1    Nagle, R.B.2    Bowden, G.T.3
  • 49
    • 0037455716 scopus 로고    scopus 로고
    • Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling
    • Zhang D, Brodt P. Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling. Oncogene 2003;22:974-982
    • (2003) Oncogene , vol.22 , pp. 974-982
    • Zhang, D.1    Brodt, P.2
  • 50
    • 70349255654 scopus 로고    scopus 로고
    • Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways
    • Zhang Z, Song T, Jin Y, et al. Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways. Int J Gynecol Cancer 2009;19:998-1003.
    • (2009) Int J Gynecol Cancer , vol.19 , pp. 998-1003
    • Zhang, Z.1    Song, T.2    Jin, Y.3
  • 51
    • 0037313015 scopus 로고    scopus 로고
    • Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors
    • Pelletier S, Duhamel F, Coulombe P, Popoff MR, Meloche S. Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors. Mol Cell Biol 2003;23:1316-1333
    • (2003) Mol Cell Biol , vol.23 , pp. 1316-1333
    • Pelletier, S.1    Duhamel, F.2    Coulombe, P.3    Popoff, M.R.4    Meloche, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.