Loss of breast cancer metastasis suppressor 1 promotes ovarian cancer cell metastasis by increasing chemokine receptor 4 expression

Oncology Reports

Volumn 27, Issue 4, 2012, Pages 1011-1018

  Sheng, Xiu Jie ^a   Zhou, Ying Qun ^a   Song, Qing Yuan ^a   Zhou, Dong Mei ^a   Liu, Qi Cai ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer metastasis suppressor 1; Chemokine receptor 4; Metastasis; Ovarian neoplasm; RNA interference

Indexed keywords

BREAST CANCER METASTASIS SUPPRESSOR 1; CHEMOKINE RECEPTOR CXCR4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ONCOPROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CANCER CELL; CELL ADHESION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CULTURE MEDIA, CONDITIONED; DOWN-REGULATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; GENE THERAPY; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEOVASCULARIZATION, PHYSIOLOGIC; NF-KAPPA B; OVARIAN NEOPLASMS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION; UP-REGULATION;

EID: 84863020036     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1596     Document Type: Article

References (29)

1. Moss C and Kaye SB: Ovarian cancer: progress and continuing controversies in management. Eur J Cancer 38: 1701-1707, 2002.
2. Seraj MJ, Samant RS, Verderame MF and Welch DR: Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13. Cancer Res 60: 2764-2769, 2000. (Pubitemid 30395788)
3. Shevde LA, Samant RS, Goldberg SF, Sikaneta T, Alessandrini A, Donahue HJ, Mauger DT and Welch DR: Suppression of human melanoma metastasis by the metastasis suppressor gene, BRMS1. Exp Cell Res 273: 229-239, 2002. (Pubitemid 34920673)
4. Zhang S, Lin QD and Di W: Suppression of human ovarian carcinoma metastasis by the metastasis-suppressor gene, BRMS1. Int J Gynecol Cancer 16: 522-531, 2006.
5. Chen X, Xu Z and Wang Y: Recent advances in breast cancer metastasis suppressor 1. Int J Biol Markers 26: 1-8, 2011.
6. DeWald DB, Torabinejad J, Samant RS, Johnston D, Erin N, Shope JC, Xie Y and Welch DR: Metastasis suppression by breast cancer metastasis suppressor 1 involves reduction of phospho- inositide signaling in MDA-MB-435 breast carcinoma cells. Cancer Res 65: 713-717, 2005. (Pubitemid 40216427)
7. Cicek M, Fukuyama R, Welch DR, Sizemore N and Casey G: Breast cancer metastasis suppressor 1 inhibits gene expression by targeting nuclear factor-kappaB activity. Cancer Res 65: 3586-3595, 2005. (Pubitemid 40616334)
8. Samant RS, Clark DW, Fillmore RA, Cicek M, Metge BJ, Chandramouli KH, Chambers AF, Casey G, Welch DR and Shevde LA: Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation. Mol Cancer 6: 6, 2007.
9. Cicek M, Fukuyama R, Cicek MS, Sizemore S, Welch DR, Sizemore N and Casey G: BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-κB binding site of the uPA promoter. Clin Exp Metastasis 26: 229-237, 2009.
10. Hurst DR, Edmonds MD, Scott GK, Benz CC, Vaidya KS and Welch DR: Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res 69: 1279-1283, 2009.
11. Li J, Cheng Y, Tai D, Martinka M, Welch DR and Li G: Prognostic significance of BRMS1 expression in human melanoma and its role in tumor angiogenesis. Oncogene 30: 896-906, 2011.
12. Yang J, Zhang B, Lin Y, Yang Y, Liu X and Lu F: Breast cancer metastasis suppressor 1 inhibits SDF-1α-induced migration of non-small cell lung cancer by decreasing CXCR4 expression. Cancer Lett 269: 46-56, 2008.
13. Kruizinga RC, Bestebroer J, Berghuis P, de Haas CJ, Links TP, de Vries EG and Walenkamp AM: Role of chemokines and their receptors in cancer. Curr Pharm Des 15: 3396-3416, 2009.
14. Manu KA, Shanmugam MK, Rajendran P, Li F, Ramachandran L, Hay HS, Kannaiyan R, Swamy SN, Vail S, Kapoor S, Ramesh B, Bist P, Koay ES, Lim LH, Ahn KS, Kumar AP and Sethi G: Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4. Mol Cancer 10: 107, 2011.
15. Zhao BC, Wang ZJ, Mao WZ, Ma HC, Han JG, Zhao B and Xu HM: CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinoma. World J Gastroenterol 17: 2389-2396, 2011.
16. Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A and Kikkawa F: Involvement of SDF-1α/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma. Int J Cancer 122: 91-99, 2008. (Pubitemid 350209982)
17. Chu CY, Cha ST, Lin WC, Lu PH, Tan CT, Chang CC, Lin BR, Jee SH and Kuo ML: Stromal cell-derived factor-1 α (SDF-1 α/CXCL12)-enhanced angiogenesis of human basal cell carcinoma cells involves ERK1/2-NF-κB/ interleukin-6 pathway. Carcinogenesis 30: 205-213, 2009.
18. Ping YF, Yao XH, Jiang JY, Zhao LT, Yu SC, Jiang T, Lin MC, Chen JH, Wang B, Zhang R, Cui YH, Qian C, Wang J and Bian XW: The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signaling. J Pathol 224: 344-354, 2011.
19. Helbig G, Christopherson KW II, Bhat-Nakshatri P, Kumar S, Kishimoto H, Miller KD, Broxmeyer HE and Nakshatri H: NF-κB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J Bilo Chem 278: 21631-21638, 2003. (Pubitemid 36792563)
20. Chambers AF, Groom AC and MacDonald IC: Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2: 563-572, 2002. (Pubitemid 37328923)
21. Hedley BD, Vaidya KS, Phadke P, Mackenzie L, Dales DW, Postenka CO, MacDonald IC and Chambers AF: BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation. Clin Exp Metastasis 25: 727-740, 2008.
22. Phadke PA, Vaidya KS, Nash KT, Hurst DR and Welch DR: BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process. Am J Pathol 172: 809-817, 2008. (Pubitemid 351354552)
23. Stark AM, Tongers K, Maass N, Mehdorn HM and Held-Feindt J: Reduced metastasis-suppressor gene mRNA-expression in breast cancer brain metastases. J Cancer Res Clin Oncol 131: 191-198, 2005. (Pubitemid 40175014)
24. Hicks DG, Yoder BJ, Short S, Tarr S, Prescott N, Crowe JP, Dawson AE, Budd GT, Sizemore S, Cicek M, Choueiri TK, Tubbs RR, Gaile D, Nowak N, Accavitti-Loper MA, Frost AR, Welch DR and Casey G: Loss of breast cancer metastasis suppressor 1 protein expression predicts reduced disease-free survival in subsets of breast cancer patients. Clin Cancer Res 12: 6702-6708, 2006. (Pubitemid 44876838)
25. Zhao XL and Wang P: Expression of SATB1 and BRMS1 in ovarian serous adenocarcinoma and its relationship with clinicopathological features. Sichuan Da Xue Xue Bao Yi Xue Ban 42: 82-85, 105, 2011 (In Chinese).
26. Smith PW, Liu Y, Siefert SA, Moskaluk CA, Petroni GR and Jones DR: Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer. Cancer Lett 276: 196-203, 2009.
27. Zhang Z, Yamashita H, Toyama T, Yamamoto Y, Kawasoe T and Iwase H: Reduced expression of the breast cancer metastasis suppressor 1 mRNA is correlated with poor progress in breast cancer. Clin Cancer Res 12: 6410-6414, 2006. (Pubitemid 44799712)
28. Miyanishi N, Suzuki Y, Simizu S, Kuwabara Y, Banno K and Umezawa K: Involvement of autocrine CXCL12/CXCR4 system in the regulation of ovarian carcinoma cell invasion. Biochem Biophys Res Commun 403: 154-159, 2010.
29. Chua AW, Hay HS, Rajendran P, Shanmugam MK, Li F, Bist P, Koay ES, Lim LH, Kumar AP and Sethi G: Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells. Biochem Pharmacol 80: 1553-1562, 2010.