Unfolded protein response regulates cardiac sodium current in systolic human heart failure

Circulation: Arrhythmia and Electrophysiology

Volumn 6, Issue 5, 2013, Pages 1018-1024

  Gao, Ge ^a   Xie, An ^a   Zhang, Jianhua ^b   Herman, Amanda M ^b   Jeong, Euy Myoung ^a   Gu, Lianzhi ^a   Liu, Man ^a   Yang, Kai Chien ^a   Kamp, Timothy J ^b   Dudley, Samuel C ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Heart failure; Humans; PERK kinase; Sodium channels

Indexed keywords

ANGIOTENSIN II; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV4.3; PROTEIN KINASE R; SODIUM CHANNEL NAV1.5; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; UNCLASSIFIED DRUG; CALRETICULIN; CCAAT ENHANCER BINDING PROTEIN; EIF2AK3 PROTEIN, HUMAN; SCN5A PROTEIN, HUMAN; SODIUM CHANNEL;

ALTERNATIVE RNA SPLICING; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HEART FAILURE; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; LEFT VENTRICULAR SYSTOLIC DYSFUNCTION; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SODIUM CURRENT; UNFOLDED PROTEIN RESPONSE; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; HEART FUNCTION TEST; METABOLISM; PATHOPHYSIOLOGY; PERK KINASE; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SYSTOLIC HEART FAILURE; WESTERN BLOTTING;

HEART FAILURE; HUMANS; PERK KINASE; SODIUM CHANNELS;

ANGIOTENSIN II; BLOTTING, WESTERN; CALRETICULIN; CCAAT-ENHANCER-BINDING PROTEINS; EIF-2 KINASE; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; ENDOPLASMIC RETICULUM; HEART FAILURE, SYSTOLIC; HUMANS; MYOCYTES, CARDIAC; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM CHANNELS; TRANSFECTION; UNFOLDED PROTEIN RESPONSE;

EID: 84891542157     PISSN: 19413149     EISSN: 19413084     Source Type: Journal    
DOI: 10.1161/circep.113.000274     Document Type: Article

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