A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Nav1.5 and Kv4.3 channel currents

Heart Rhythm

Volumn 9, Issue 5, 2012, Pages 760-769

  Hu, Dan ^a   Barajas Martínez, Hector ^a   Medeiros Domingo, Argelia ^b   Crotti, Lia ^c,d,e   Veltmann, Christian ^f   Schimpf, Rainer ^f   Urrutia, Janire ^g   Alday, Aintzane ^g   Casis, Oscar ^g   Pfeiffer, Ryan ^a   Burashnikov, Elena ^a   Caceres, Gabriel ^a   Tester, David J ^b   Wolpert, Christian ^h   Borggrefe, Martin ^f   Schwartz, Peter ^c,e,i,j,k,l   Ackerman, Michael J ^b   Antzelevitch, Charles ^a  

^a MASONIC MEDICAL RESEARCH LABORATORY   (United States)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF PAVIA   (Italy)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^f UNIVERSITY OF HEIDELBERG   (Germany)

^g UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^h KLINIKUM LUDWIGSBURG   (Germany)

ⁱ ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^j UNIVERSITY OF CAPE TOWN   (South Africa)

^k STELLENBOSCH UNIVERSITY   (South Africa)

^l KING SAUD UNIVERSITY   (Saudi Arabia)

more..

Author keywords

Arrhythmias; Brugada syndrome; Potassium; SCN1Bb; Sodium; Sudden infant death syndrome

Indexed keywords

POTASSIUM CHANNEL KV4.3; SHAL POTASSIUM CHANNEL; SODIUM CHANNEL NAV1.5; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRUGADA SYNDROME; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ELECTROCARDIOGRAPHY; EXON; FEMALE; FEVER; GENE; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; HEART ARREST; HUMAN; INFANT; INTRON; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCN1BB GENE; ST SEGMENT ELEVATION; SUDDEN INFANT DEATH SYNDROME;

ADULT; ARRHYTHMIAS, CARDIAC; BLOTTING, WESTERN; BRUGADA SYNDROME; ELECTROCARDIOGRAPHY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT; MALE; MIDDLE AGED; MOLECULAR BIOLOGY; MUTATION; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; POLYMORPHISM, GENETIC; POTASSIUM CHANNELS; SUDDEN INFANT DEATH; VOLTAGE-GATED SODIUM CHANNEL BETA-1 SUBUNIT;

EID: 84859978568     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2011.12.006     Document Type: Article

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