Towards cytotoxic and selective derivatives of maslinic acid

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 1, 2014, Pages 594-615

  Siewert, Bianka ^a   Pianowski, Elke ^a   Obernauer, Anja ^a   Csuk, René ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Annexin V assay; Antitumor; Apoptosis; Cancer; Caspase activity; Cell cycle investigations; DNA laddering; Esters; Maslinic acid; SRB assay

Indexed keywords

(2ALPHA,3BETA) 2,3 DIACETOXY OLEAN 12 EN 28 ACID; (3 PHENYL) PROPYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; (3 PHENYL) PROPYL 2 ENYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; (3ALPHA) 3 ACETOXY OLEAN 12 EN 28 ACID; (4 OXA 4 PHENYL) BUTYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; (CYCLOHEXYL) METHYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; 2,4 DICHLOROBENZYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; 4 BROMOBENZYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; 4 CHLOROBENZYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; 4 CHLOROBENZYL (3BETA) 3 HYDROXY OLEAN 12 EN 28 OATE; 4 CHLOROBENZYL (3BETA) 3 HYDROXY URS 12 EN 28 OATE; 4 FLUOROBENZYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; 4 METHOXYBENZYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; 4 NITROBENZYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; ANTINEOPLASTIC AGENT; BENZYL (2ALPHA,3BETA) 2,3 DIACETOXY OLEAN 12 EN 28 AMIDE; BENZYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 AMIDE; BENZYL (2BETA,3ALPHA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; BENZYL (3BETA) 3 ACETOXY OLEAN 12 EN 28 AMIDE; BENZYL (3BETA) 3 HYDROXY OLEAN 12 EN 28 AMIDE; BENZYL (3BETA) 3 HYDROXY OLEAN 12 EN 28 OATE; BENZYL (3BETA) 3 HYDROXY URS 12 EN 28 OATE; MASLINIC ACID; META CHLOROBENZYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; META CHLOROBENZYL (3BETA) 3 HYDROXY OLEAN 12 EN 28 OATE; META CHLOROBENZYL (3BETA) 3 HYDROXY URS 12 EN 28 OATE; ORTHO CHLOROBENZYL (2ALPHA,3BETA) 2,3 DIHYDROXY OLEAN 12 EN 28 OATE; ORTHO CHLOROBENZYL (3BETA) 3 HYDROXY OLEAN 12 EN 28 OATE; ORTHO CHLOROBENZYL (3BETA) 3 HYDROXY URS 12 EN 28 OATE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CONCENTRATION RESPONSE; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; FIBROBLAST; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IC 50; NONHUMAN; OVARY CANCER;

ANNEXIN V ASSAY; ANTITUMOR; APOPTOSIS; CANCER; CASPASE ACTIVITY; CELL CYCLE INVESTIGATIONS; DNA LADDERING; ESTERS; MASLINIC ACID; SRB ASSAY;

AMIDES; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; ESTERS; HUMANS; MICE; MOLECULAR STRUCTURE; TRITERPENES;

EID: 84891481757     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.10.047     Document Type: Article

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