Alkylidene branched lupane derivatives: Synthesis and antitumor activity

European Journal of Medicinal Chemistry

Volumn 53, Issue , 2012, Pages 337-345

  Csuk, René ^a   Stark, Sebastian ^a   Nitsche, Christoph ^a   Barthel, Alexander ^a   Siewert, Bianka ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Antitumor activity; Apoptosis; Betulonic acid; Methylene compounds

Indexed keywords

2 METHYLENE 28 OXO 28 THIOMORPHOLIN 4 YL LUP 20(29)EN 3 ONE; 2 METHYLENE 3 OXOLUP 20(29)EN 28 AL; ACRIDINE ORANGE; ANTINEOPLASTIC AGENT; ETHIDIUM BROMIDE; LIPOSOME; METHYL (2 E) 2 ETHYLIDEN 3 OXOLUP 20(29)EN 28 OATE; METHYL 2 METHYLENE 3 OXOLUP 20(29)EN 28 OATE; METHYL 3 OXO 2 PROP 2 EN 1 YLID LUP 20(29)EN 28 OATE; METHYL(2A) 2 (2 NITROETHYL) 3 OXOLUP 20(29)EN 28 OATE; METHYL(2A) 2 [(DIMETHYLAMINO)METHYL] 3 OXOLUP 20(29)EN 28 OATE; METHYL(2A) 2 [[(2 HYDROXYETHYL)SULFONYL]METHYL] 3 OXOLUP 20(29)EN 28 OATE; METHYL(2A) 2 [[(2 HYDROXYETHYL)THIO]METHYL] 3 OXOLUP 20(29)EN 28 OATE; SPIRO[PYRAZOL 3',2 28 METHOXY 3 OXOLUP 20(29) EN 28 ONE]; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; NANOENCAPSULATION; STAINING;

ALKENES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMISTRY TECHNIQUES, SYNTHETIC; HUMANS; HYDROXIDES; INHIBITORY CONCENTRATION 50; OXIDATION-REDUCTION; TRITERPENES;

EID: 84861628814     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.04.023     Document Type: Article

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