메뉴 건너뛰기




Volumn 59, Issue 8, 2007, Pages 1087-1093

A novel synthetic oleanolic acid derivative with amino acid conjugate suppresses tumour growth by inducing cell cycle arrest

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYCLIN D; CYCLIN DEPENDENT KINASE; N[(3BETA) 3 (ACETOXY) 28 OXOOLEAN 12 EN 28 YL]GLYCINE METHYLESTER; OLEANOLIC ACID; OLEANOLIC ACID DERIVATIVE; PROTEIN P15; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

EID: 34547955762     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.8.0005     Document Type: Article
Times cited : (14)

References (30)
  • 1
    • 0033584217 scopus 로고    scopus 로고
    • Synthesis and evaluation of potential complement inhibitory semisynthetic analogs of oleanolic acid
    • Assefa, H., Nimrod, A., Walker, L., Sindelar, R. (1999) Synthesis and evaluation of potential complement inhibitory semisynthetic analogs of oleanolic acid. Bioorg. Med. Chem. Lett. 9: 1889-1894
    • (1999) Bioorg. Med. Chem. Lett , vol.9 , pp. 1889-1894
    • Assefa, H.1    Nimrod, A.2    Walker, L.3    Sindelar, R.4
  • 3
    • 0035964699 scopus 로고    scopus 로고
    • Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has antiinflammatory activity
    • Giner-Larza, E. M., Manez, S., Recio, M. C., Giner, R. M., Prieto, J. M., Cerda-Nicolas, M., Rios, J. L. (2001) Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has antiinflammatory activity. Eur. J. Pharmacol. 428: 137-143
    • (2001) Eur. J. Pharmacol , vol.428 , pp. 137-143
    • Giner-Larza, E.M.1    Manez, S.2    Recio, M.C.3    Giner, R.M.4    Prieto, J.M.5    Cerda-Nicolas, M.6    Rios, J.L.7
  • 4
    • 1642442530 scopus 로고    scopus 로고
    • Evidence supporting a role for calcium in apoptosis induction by the synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid (CDDO)
    • Hail, N. Jr., Konopleva, M., Sporn, M., Lotan, R., Andreeff, M. (2004) Evidence supporting a role for calcium in apoptosis induction by the synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid (CDDO). J. Biol. Chem. 279: 11179-11187
    • (2004) J. Biol. Chem , vol.279 , pp. 11179-11187
    • Hail Jr., N.1    Konopleva, M.2    Sporn, M.3    Lotan, R.4    Andreeff, M.5
  • 5
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell, L. H., Kastan, M.B. (1994) Cell cycle control and cancer. Science 266: 1821-1828
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 6
    • 0034597578 scopus 로고    scopus 로고
    • Synthetic oleanane and ursane triterpenoids with modified rings A and C: A series of highly active inhibitors of nitric oxide production in mouse macrophage
    • Honda, T., Rounds, BA.V., Bore, L., Finlay, H. J., Favaloro, F. G Jr., Suh, N., Wang, Y., Sporn, M. B., Gribble, G. W. (2000) Synthetic oleanane and ursane triterpenoids with modified rings A and C: A series of highly active inhibitors of nitric oxide production in mouse macrophage. J. Med. Chem. 43: 4233-4246
    • (2000) J. Med. Chem , vol.43 , pp. 4233-4246
    • Honda, T.1    Rounds, B.V.2    Bore, L.3    Finlay, H.J.4    Favaloro Jr., F.G.5    Suh, N.6    Wang, Y.7    Sporn, M.B.8    Gribble, G.W.9
  • 7
    • 0031024074 scopus 로고    scopus 로고
    • Effects of oleanolic acid and ursolic acid on inhibiting tumor growth and enhancing the recovery of hematopoietic system postirradiation in mice
    • Hsu, H. Y., Yang, J. J., Lin, C. C. (1997) Effects of oleanolic acid and ursolic acid on inhibiting tumor growth and enhancing the recovery of hematopoietic system postirradiation in mice. Cancer Lett. 111: 7-13
    • (1997) Cancer Lett , vol.111 , pp. 7-13
    • Hsu, H.Y.1    Yang, J.J.2    Lin, C.C.3
  • 8
    • 33644650897 scopus 로고    scopus 로고
    • Anti-tumor activity of a 3-oxo derivative of oleanolic acid
    • Huang, D., Ding, Y., Li, Y., Zhang, W. M., Fang, W. S., Chen, X. G. (2006) Anti-tumor activity of a 3-oxo derivative of oleanolic acid. Cancer Lett. 233: 289-296
    • (2006) Cancer Lett , vol.233 , pp. 289-296
    • Huang, D.1    Ding, Y.2    Li, Y.3    Zhang, W.M.4    Fang, W.S.5    Chen, X.G.6
  • 11
    • 0034077629 scopus 로고    scopus 로고
    • The novel triterpenoid 2-cyano-3,12-dioxoolean-1, 9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism
    • Ito, Y., Pandey, P., Place, A., Sporn, M. B., Gribble, G. W., Honda, T., Kharbanda S., Kufe, D. (2000) The novel triterpenoid 2-cyano-3,12-dioxoolean-1, 9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism. Cell Growth Differ. 11: 261-267
    • (2000) Cell Growth Differ , vol.11 , pp. 261-267
    • Ito, Y.1    Pandey, P.2    Place, A.3    Sporn, M.B.4    Gribble, G.W.5    Honda, T.6    Kharbanda, S.7    Kufe, D.8
  • 12
    • 0032911531 scopus 로고    scopus 로고
    • Inhibition of cytochrome P450 2E1 expression by oleanolic acid: Hepatoprotective effects against carbon tetrachloride-induced hepatic injury
    • Jeong, H. G. (1999) Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury. Toxicol. Lett. 105: 215-222
    • (1999) Toxicol. Lett , vol.105 , pp. 215-222
    • Jeong, H.G.1
  • 13
    • 0033583466 scopus 로고    scopus 로고
    • Preparation of amino acid conjugates of betulinic acid with activity against human melanoma
    • Jeong, H. J., Chai, H. B., Park, S. Y., Kim, D. S. H. L. (1999) Preparation of amino acid conjugates of betulinic acid with activity against human melanoma. Bioorg. Med. Chem. Lett. 9: 1201-1204
    • (1999) Bioorg. Med. Chem. Lett , vol.9 , pp. 1201-1204
    • Jeong, H.J.1    Chai, H.B.2    Park, S.Y.3    Kim, D.S.H.L.4
  • 14
    • 0141507973 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor γ by a novel synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells
    • Lapillonne, H., Konopleva, M., Tsao, T., Gold, D., McQueen, T., Sutherland, R. L., Madden, T., Andreeff, M. (2003) Activation of peroxisome proliferator-activated receptor γ by a novel synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells. Cancer Res. 63: 5926-5939
    • (2003) Cancer Res , vol.63 , pp. 5926-5939
    • Lapillonne, H.1    Konopleva, M.2    Tsao, T.3    Gold, D.4    McQueen, T.5    Sutherland, R.L.6    Madden, T.7    Andreeff, M.8
  • 15
    • 0029567968 scopus 로고
    • Pharmacology of oleanolic acid and ursolic acid
    • Liu, J. (1995) Pharmacology of oleanolic acid and ursolic acid. J. Ethnopharmacol. 49: 57-68
    • (1995) J. Ethnopharmacol , vol.49 , pp. 57-68
    • Liu, J.1
  • 16
    • 23044440041 scopus 로고    scopus 로고
    • Oleanolic acid and ursolic acid: Research perspective
    • Liu, J. (2005) Oleanolic acid and ursolic acid: research perspective. J. Ethnopharmacol. 100: 92-94
    • (2005) J. Ethnopharmacol , vol.100 , pp. 92-94
    • Liu, J.1
  • 17
    • 0036783521 scopus 로고    scopus 로고
    • Mechanisms of cytotoxicity and antitumor activity of gold (I) phosphine complexes: The possible role of mitochondria
    • McKeage, M. J., Maharaj, L., Berners-Price, S. J. (2002) Mechanisms of cytotoxicity and antitumor activity of gold (I) phosphine complexes: the possible role of mitochondria. Coord. Chem. Rev. 232: 127-135
    • (2002) Coord. Chem. Rev , vol.232 , pp. 127-135
    • McKeage, M.J.1    Maharaj, L.2    Berners-Price, S.J.3
  • 18
    • 0031784009 scopus 로고    scopus 로고
    • Inhibitory effect of oleanolic acid on 12-O-tetradecanoylphorbol-13-acetate-induced gene expression in mouse skin
    • Oguro, T., Liu, J., Klaassen, C. D., Yoshida, T. (1998) Inhibitory effect of oleanolic acid on 12-O-tetradecanoylphorbol-13-acetate-induced gene expression in mouse skin. Toxicol. Sci. 45: 88-93
    • (1998) Toxicol. Sci , vol.45 , pp. 88-93
    • Oguro, T.1    Liu, J.2    Klaassen, C.D.3    Yoshida, T.4
  • 19
    • 33644746743 scopus 로고    scopus 로고
    • A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity
    • Radhakrishnan, K., Gartel, A. L. (2006) A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity. Cancer Res. 66: 3264-3270
    • (2006) Cancer Res , vol.66 , pp. 3264-3270
    • Radhakrishnan, K.1    Gartel, A.L.2
  • 20
    • 0024374724 scopus 로고
    • Appraisal of the MTT assay as a rapid test of chemosensitivity in acute myeloid leukaemia
    • Sargent, J. M., Taylor, C. G. (1989) Appraisal of the MTT assay as a rapid test of chemosensitivity in acute myeloid leukaemia. Br. J. Cancer 60: 206-210
    • (1989) Br. J. Cancer , vol.60 , pp. 206-210
    • Sargent, J.M.1    Taylor, C.G.2
  • 21
    • 20444422472 scopus 로고    scopus 로고
    • Pharmacological aspects of cytotoxic polyamine analogs and derivatives for cancer therapy
    • Seiler, N. (2005) Pharmacological aspects of cytotoxic polyamine analogs and derivatives for cancer therapy. Pharmacol. Ther. 107: 99-119
    • (2005) Pharmacol. Ther , vol.107 , pp. 99-119
    • Seiler, N.1
  • 22
    • 33645802169 scopus 로고    scopus 로고
    • Cyclin-dependent kinase pathways as targets for cancer treatment
    • Shapiro, G. I. (2006) Cyclin-dependent kinase pathways as targets for cancer treatment. J. Clin. Oncol. 24: 1770-1783
    • (2006) J. Clin. Oncol , vol.24 , pp. 1770-1783
    • Shapiro, G.I.1
  • 23
    • 0033399453 scopus 로고    scopus 로고
    • Anticancer drug targets: Cell cycle and checkpoint control
    • Shapiro, G. I., Harper, J. W. (1999) Anticancer drug targets: cell cycle and checkpoint control. J. Clin. Invest. 104: 1645-1653
    • (1999) J. Clin. Invest , vol.104 , pp. 1645-1653
    • Shapiro, G.I.1    Harper, J.W.2
  • 25
    • 0033555614 scopus 로고    scopus 로고
    • Suh, N., Wang, Y., Honda, T., Gribble, G. W., Dmitrovsky, E., Hickey, W. F., Maue, R. A., Place, A. E., Porter, D. M., Spinella, M. J., Williams, C. R., Wu, G., Dannenberg, A. J., Flanders, K. C., Letterio, J. J., Mangelsdorf, D. J., Nathan, C. F., Nguyen, L., Porter, W. W., Ren, R. F., Roberts, A. B., Roche, N. S., Subbaramaiah, K., Sporn M. B. (1999) A novel synthetic oleanane triterpenoid, 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity. Cancer Res. 59: 336-341
    • Suh, N., Wang, Y., Honda, T., Gribble, G. W., Dmitrovsky, E., Hickey, W. F., Maue, R. A., Place, A. E., Porter, D. M., Spinella, M. J., Williams, C. R., Wu, G., Dannenberg, A. J., Flanders, K. C., Letterio, J. J., Mangelsdorf, D. J., Nathan, C. F., Nguyen, L., Porter, W. W., Ren, R. F., Roberts, A. B., Roche, N. S., Subbaramaiah, K., Sporn M. B. (1999) A novel synthetic oleanane triterpenoid, 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity. Cancer Res. 59: 336-341
  • 26
    • 0030916439 scopus 로고    scopus 로고
    • Elevated activity of cyclin-dependent kinase 6 in human squamous cell carcinoma lines
    • Timmermann, S., Hinds, P. W., Munger, K. (1997) Elevated activity of cyclin-dependent kinase 6 in human squamous cell carcinoma lines. Cell Growth Differ. 8: 361-370
    • (1997) Cell Growth Differ , vol.8 , pp. 361-370
    • Timmermann, S.1    Hinds, P.W.2    Munger, K.3
  • 27
    • 0034949925 scopus 로고    scopus 로고
    • Quercetin inhibits the invasion and mobility of murine melanoma B16-BL6 cells through inducing apoptosis via decreasing Bcl-2 expression
    • Zhang, X. M., Xu, Q., Saiki, I. (2000) Quercetin inhibits the invasion and mobility of murine melanoma B16-BL6 cells through inducing apoptosis via decreasing Bcl-2 expression. Clin. Exp. Metastasis 18: 415-421
    • (2000) Clin. Exp. Metastasis , vol.18 , pp. 415-421
    • Zhang, X.M.1    Xu, Q.2    Saiki, I.3
  • 28
    • 14644390185 scopus 로고    scopus 로고
    • Synthesis and activity of oleanolic acid derivatives, a novel class of inhibitors of osteoclast formation
    • Zhang, Y., Li, J. X., Zhao, J. W., Wang, S. Z., Pan, Y., Tanaka, K., Kadota, S. (2005) Synthesis and activity of oleanolic acid derivatives, a novel class of inhibitors of osteoclast formation. Bioorg. Med. Chem. Lett. 15: 1629-1632
    • (2005) Bioorg. Med. Chem. Lett , vol.15 , pp. 1629-1632
    • Zhang, Y.1    Li, J.X.2    Zhao, J.W.3    Wang, S.Z.4    Pan, Y.5    Tanaka, K.6    Kadota, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.