-
1
-
-
0033584217
-
Synthesis and evaluation of potential complement inhibitory semisynthetic analogs of oleanolic acid
-
Assefa, H., Nimrod, A., Walker, L., Sindelar, R. (1999) Synthesis and evaluation of potential complement inhibitory semisynthetic analogs of oleanolic acid. Bioorg. Med. Chem. Lett. 9: 1889-1894
-
(1999)
Bioorg. Med. Chem. Lett
, vol.9
, pp. 1889-1894
-
-
Assefa, H.1
Nimrod, A.2
Walker, L.3
Sindelar, R.4
-
2
-
-
33645393211
-
Flavopiridol in patients with relapsed or refractory multiple myeloma: A phase 2 trial with clinical and pharmacodynamic end-points
-
Dispenzieri, A., Gertz, M. A., Lacy, M. Q., Geyer, S. M., Fitch, T. R., Fenton, R. G., Fonseca R., Isham, C. R., Ziesmer, S. C., Erlichman, C., Bible, K. C. (2006) Flavopiridol in patients with relapsed or refractory multiple myeloma: a phase 2 trial with clinical and pharmacodynamic end-points. Haematologica 91: 390-393
-
(2006)
Haematologica
, vol.91
, pp. 390-393
-
-
Dispenzieri, A.1
Gertz, M.A.2
Lacy, M.Q.3
Geyer, S.M.4
Fitch, T.R.5
Fenton, R.G.6
Fonseca, R.7
Isham, C.R.8
Ziesmer, S.C.9
Erlichman, C.10
Bible, K.C.11
-
3
-
-
0035964699
-
Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has antiinflammatory activity
-
Giner-Larza, E. M., Manez, S., Recio, M. C., Giner, R. M., Prieto, J. M., Cerda-Nicolas, M., Rios, J. L. (2001) Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has antiinflammatory activity. Eur. J. Pharmacol. 428: 137-143
-
(2001)
Eur. J. Pharmacol
, vol.428
, pp. 137-143
-
-
Giner-Larza, E.M.1
Manez, S.2
Recio, M.C.3
Giner, R.M.4
Prieto, J.M.5
Cerda-Nicolas, M.6
Rios, J.L.7
-
4
-
-
1642442530
-
Evidence supporting a role for calcium in apoptosis induction by the synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid (CDDO)
-
Hail, N. Jr., Konopleva, M., Sporn, M., Lotan, R., Andreeff, M. (2004) Evidence supporting a role for calcium in apoptosis induction by the synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid (CDDO). J. Biol. Chem. 279: 11179-11187
-
(2004)
J. Biol. Chem
, vol.279
, pp. 11179-11187
-
-
Hail Jr., N.1
Konopleva, M.2
Sporn, M.3
Lotan, R.4
Andreeff, M.5
-
5
-
-
0028568315
-
Cell cycle control and cancer
-
Hartwell, L. H., Kastan, M.B. (1994) Cell cycle control and cancer. Science 266: 1821-1828
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
6
-
-
0034597578
-
Synthetic oleanane and ursane triterpenoids with modified rings A and C: A series of highly active inhibitors of nitric oxide production in mouse macrophage
-
Honda, T., Rounds, BA.V., Bore, L., Finlay, H. J., Favaloro, F. G Jr., Suh, N., Wang, Y., Sporn, M. B., Gribble, G. W. (2000) Synthetic oleanane and ursane triterpenoids with modified rings A and C: A series of highly active inhibitors of nitric oxide production in mouse macrophage. J. Med. Chem. 43: 4233-4246
-
(2000)
J. Med. Chem
, vol.43
, pp. 4233-4246
-
-
Honda, T.1
Rounds, B.V.2
Bore, L.3
Finlay, H.J.4
Favaloro Jr., F.G.5
Suh, N.6
Wang, Y.7
Sporn, M.B.8
Gribble, G.W.9
-
7
-
-
0031024074
-
Effects of oleanolic acid and ursolic acid on inhibiting tumor growth and enhancing the recovery of hematopoietic system postirradiation in mice
-
Hsu, H. Y., Yang, J. J., Lin, C. C. (1997) Effects of oleanolic acid and ursolic acid on inhibiting tumor growth and enhancing the recovery of hematopoietic system postirradiation in mice. Cancer Lett. 111: 7-13
-
(1997)
Cancer Lett
, vol.111
, pp. 7-13
-
-
Hsu, H.Y.1
Yang, J.J.2
Lin, C.C.3
-
8
-
-
33644650897
-
Anti-tumor activity of a 3-oxo derivative of oleanolic acid
-
Huang, D., Ding, Y., Li, Y., Zhang, W. M., Fang, W. S., Chen, X. G. (2006) Anti-tumor activity of a 3-oxo derivative of oleanolic acid. Cancer Lett. 233: 289-296
-
(2006)
Cancer Lett
, vol.233
, pp. 289-296
-
-
Huang, D.1
Ding, Y.2
Li, Y.3
Zhang, W.M.4
Fang, W.S.5
Chen, X.G.6
-
9
-
-
25144459552
-
A new cancer diagnostic system based on a CDK profiling technology
-
Ishihara, H., Yoshida, T., Kawasaki, Y., Kobayashi, H., Yamasaki, M., Nakayama, S., Miki, E., Shohmi, K., Matsushima, T., Tada, S., Torikoshi, Y., Morita, M., Tamura, S., Hino, Y., Kamiyama, J., Sowa, Y., Tsuchihashi, Y., Yamagishi, H., Sakai, T. (2005) A new cancer diagnostic system based on a CDK profiling technology. Biochim. Biophys. Acta 1741: 226-233
-
(2005)
Biochim. Biophys. Acta
, vol.1741
, pp. 226-233
-
-
Ishihara, H.1
Yoshida, T.2
Kawasaki, Y.3
Kobayashi, H.4
Yamasaki, M.5
Nakayama, S.6
Miki, E.7
Shohmi, K.8
Matsushima, T.9
Tada, S.10
Torikoshi, Y.11
Morita, M.12
Tamura, S.13
Hino, Y.14
Kamiyama, J.15
Sowa, Y.16
Tsuchihashi, Y.17
Yamagishi, H.18
Sakai, T.19
-
11
-
-
0034077629
-
The novel triterpenoid 2-cyano-3,12-dioxoolean-1, 9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism
-
Ito, Y., Pandey, P., Place, A., Sporn, M. B., Gribble, G. W., Honda, T., Kharbanda S., Kufe, D. (2000) The novel triterpenoid 2-cyano-3,12-dioxoolean-1, 9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism. Cell Growth Differ. 11: 261-267
-
(2000)
Cell Growth Differ
, vol.11
, pp. 261-267
-
-
Ito, Y.1
Pandey, P.2
Place, A.3
Sporn, M.B.4
Gribble, G.W.5
Honda, T.6
Kharbanda, S.7
Kufe, D.8
-
12
-
-
0032911531
-
Inhibition of cytochrome P450 2E1 expression by oleanolic acid: Hepatoprotective effects against carbon tetrachloride-induced hepatic injury
-
Jeong, H. G. (1999) Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury. Toxicol. Lett. 105: 215-222
-
(1999)
Toxicol. Lett
, vol.105
, pp. 215-222
-
-
Jeong, H.G.1
-
13
-
-
0033583466
-
Preparation of amino acid conjugates of betulinic acid with activity against human melanoma
-
Jeong, H. J., Chai, H. B., Park, S. Y., Kim, D. S. H. L. (1999) Preparation of amino acid conjugates of betulinic acid with activity against human melanoma. Bioorg. Med. Chem. Lett. 9: 1201-1204
-
(1999)
Bioorg. Med. Chem. Lett
, vol.9
, pp. 1201-1204
-
-
Jeong, H.J.1
Chai, H.B.2
Park, S.Y.3
Kim, D.S.H.L.4
-
14
-
-
0141507973
-
Activation of peroxisome proliferator-activated receptor γ by a novel synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells
-
Lapillonne, H., Konopleva, M., Tsao, T., Gold, D., McQueen, T., Sutherland, R. L., Madden, T., Andreeff, M. (2003) Activation of peroxisome proliferator-activated receptor γ by a novel synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells. Cancer Res. 63: 5926-5939
-
(2003)
Cancer Res
, vol.63
, pp. 5926-5939
-
-
Lapillonne, H.1
Konopleva, M.2
Tsao, T.3
Gold, D.4
McQueen, T.5
Sutherland, R.L.6
Madden, T.7
Andreeff, M.8
-
15
-
-
0029567968
-
Pharmacology of oleanolic acid and ursolic acid
-
Liu, J. (1995) Pharmacology of oleanolic acid and ursolic acid. J. Ethnopharmacol. 49: 57-68
-
(1995)
J. Ethnopharmacol
, vol.49
, pp. 57-68
-
-
Liu, J.1
-
16
-
-
23044440041
-
Oleanolic acid and ursolic acid: Research perspective
-
Liu, J. (2005) Oleanolic acid and ursolic acid: research perspective. J. Ethnopharmacol. 100: 92-94
-
(2005)
J. Ethnopharmacol
, vol.100
, pp. 92-94
-
-
Liu, J.1
-
17
-
-
0036783521
-
Mechanisms of cytotoxicity and antitumor activity of gold (I) phosphine complexes: The possible role of mitochondria
-
McKeage, M. J., Maharaj, L., Berners-Price, S. J. (2002) Mechanisms of cytotoxicity and antitumor activity of gold (I) phosphine complexes: the possible role of mitochondria. Coord. Chem. Rev. 232: 127-135
-
(2002)
Coord. Chem. Rev
, vol.232
, pp. 127-135
-
-
McKeage, M.J.1
Maharaj, L.2
Berners-Price, S.J.3
-
18
-
-
0031784009
-
Inhibitory effect of oleanolic acid on 12-O-tetradecanoylphorbol-13-acetate-induced gene expression in mouse skin
-
Oguro, T., Liu, J., Klaassen, C. D., Yoshida, T. (1998) Inhibitory effect of oleanolic acid on 12-O-tetradecanoylphorbol-13-acetate-induced gene expression in mouse skin. Toxicol. Sci. 45: 88-93
-
(1998)
Toxicol. Sci
, vol.45
, pp. 88-93
-
-
Oguro, T.1
Liu, J.2
Klaassen, C.D.3
Yoshida, T.4
-
19
-
-
33644746743
-
A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity
-
Radhakrishnan, K., Gartel, A. L. (2006) A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity. Cancer Res. 66: 3264-3270
-
(2006)
Cancer Res
, vol.66
, pp. 3264-3270
-
-
Radhakrishnan, K.1
Gartel, A.L.2
-
20
-
-
0024374724
-
Appraisal of the MTT assay as a rapid test of chemosensitivity in acute myeloid leukaemia
-
Sargent, J. M., Taylor, C. G. (1989) Appraisal of the MTT assay as a rapid test of chemosensitivity in acute myeloid leukaemia. Br. J. Cancer 60: 206-210
-
(1989)
Br. J. Cancer
, vol.60
, pp. 206-210
-
-
Sargent, J.M.1
Taylor, C.G.2
-
21
-
-
20444422472
-
Pharmacological aspects of cytotoxic polyamine analogs and derivatives for cancer therapy
-
Seiler, N. (2005) Pharmacological aspects of cytotoxic polyamine analogs and derivatives for cancer therapy. Pharmacol. Ther. 107: 99-119
-
(2005)
Pharmacol. Ther
, vol.107
, pp. 99-119
-
-
Seiler, N.1
-
22
-
-
33645802169
-
Cyclin-dependent kinase pathways as targets for cancer treatment
-
Shapiro, G. I. (2006) Cyclin-dependent kinase pathways as targets for cancer treatment. J. Clin. Oncol. 24: 1770-1783
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 1770-1783
-
-
Shapiro, G.I.1
-
23
-
-
0033399453
-
Anticancer drug targets: Cell cycle and checkpoint control
-
Shapiro, G. I., Harper, J. W. (1999) Anticancer drug targets: cell cycle and checkpoint control. J. Clin. Invest. 104: 1645-1653
-
(1999)
J. Clin. Invest
, vol.104
, pp. 1645-1653
-
-
Shapiro, G.I.1
Harper, J.W.2
-
24
-
-
0029156978
-
Anti-angiogenic activity of triterpene acids
-
Sohn, K. H., Lee, H. Y., Chung, H. Y., Young, H. S., Yi, S. Y., Kim, K. W. (1995) Anti-angiogenic activity of triterpene acids. Cancer Lett. 94: 213-218
-
(1995)
Cancer Lett
, vol.94
, pp. 213-218
-
-
Sohn, K.H.1
Lee, H.Y.2
Chung, H.Y.3
Young, H.S.4
Yi, S.Y.5
Kim, K.W.6
-
25
-
-
0033555614
-
-
Suh, N., Wang, Y., Honda, T., Gribble, G. W., Dmitrovsky, E., Hickey, W. F., Maue, R. A., Place, A. E., Porter, D. M., Spinella, M. J., Williams, C. R., Wu, G., Dannenberg, A. J., Flanders, K. C., Letterio, J. J., Mangelsdorf, D. J., Nathan, C. F., Nguyen, L., Porter, W. W., Ren, R. F., Roberts, A. B., Roche, N. S., Subbaramaiah, K., Sporn M. B. (1999) A novel synthetic oleanane triterpenoid, 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity. Cancer Res. 59: 336-341
-
Suh, N., Wang, Y., Honda, T., Gribble, G. W., Dmitrovsky, E., Hickey, W. F., Maue, R. A., Place, A. E., Porter, D. M., Spinella, M. J., Williams, C. R., Wu, G., Dannenberg, A. J., Flanders, K. C., Letterio, J. J., Mangelsdorf, D. J., Nathan, C. F., Nguyen, L., Porter, W. W., Ren, R. F., Roberts, A. B., Roche, N. S., Subbaramaiah, K., Sporn M. B. (1999) A novel synthetic oleanane triterpenoid, 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity. Cancer Res. 59: 336-341
-
-
-
-
26
-
-
0030916439
-
Elevated activity of cyclin-dependent kinase 6 in human squamous cell carcinoma lines
-
Timmermann, S., Hinds, P. W., Munger, K. (1997) Elevated activity of cyclin-dependent kinase 6 in human squamous cell carcinoma lines. Cell Growth Differ. 8: 361-370
-
(1997)
Cell Growth Differ
, vol.8
, pp. 361-370
-
-
Timmermann, S.1
Hinds, P.W.2
Munger, K.3
-
27
-
-
0034949925
-
Quercetin inhibits the invasion and mobility of murine melanoma B16-BL6 cells through inducing apoptosis via decreasing Bcl-2 expression
-
Zhang, X. M., Xu, Q., Saiki, I. (2000) Quercetin inhibits the invasion and mobility of murine melanoma B16-BL6 cells through inducing apoptosis via decreasing Bcl-2 expression. Clin. Exp. Metastasis 18: 415-421
-
(2000)
Clin. Exp. Metastasis
, vol.18
, pp. 415-421
-
-
Zhang, X.M.1
Xu, Q.2
Saiki, I.3
-
28
-
-
14644390185
-
Synthesis and activity of oleanolic acid derivatives, a novel class of inhibitors of osteoclast formation
-
Zhang, Y., Li, J. X., Zhao, J. W., Wang, S. Z., Pan, Y., Tanaka, K., Kadota, S. (2005) Synthesis and activity of oleanolic acid derivatives, a novel class of inhibitors of osteoclast formation. Bioorg. Med. Chem. Lett. 15: 1629-1632
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 1629-1632
-
-
Zhang, Y.1
Li, J.X.2
Zhao, J.W.3
Wang, S.Z.4
Pan, Y.5
Tanaka, K.6
Kadota, S.7
-
29
-
-
0035904867
-
Synthesis and anti-HIV activity of oleanolic acid derivatives
-
Zhu, Y. M., Shen, J. K., Wang, H. K., Cosentino, L. M., Lee, K. H. (2001) Synthesis and anti-HIV activity of oleanolic acid derivatives. Bioorg. Med. Chem. Lett. 11: 3115-3118
-
(2001)
Bioorg. Med. Chem. Lett
, vol.11
, pp. 3115-3118
-
-
Zhu, Y.M.1
Shen, J.K.2
Wang, H.K.3
Cosentino, L.M.4
Lee, K.H.5
-
30
-
-
0029664339
-
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
-
Zuo, L., Weger, J., Yang, Q., Goldstein, A. M., Tucker, M. A., Walker, G. J., Hayward, N., Dracopoli, N.C. (1996) Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma. Nat. Genet. 12: 97-99
-
(1996)
Nat. Genet
, vol.12
, pp. 97-99
-
-
Zuo, L.1
Weger, J.2
Yang, Q.3
Goldstein, A.M.4
Tucker, M.A.5
Walker, G.J.6
Hayward, N.7
Dracopoli, N.C.8
|