Novel antimitotic activity of 2-hydroxy-4-methoxy-2′,3′- benzochalcone (HymnPro) through the inhibition of tubulin polymerization

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 51, 2013, Pages 12588-12597

  Shin, Soon Young ^a,b   Kim, Ji Ho ^a   Yoon, Hyuk ^a   Choi, Yang Kyu ^a   Koh, Dongsoo ^c   Lim, Yoongho ^a   Lee, Young Han ^a,b  

^a Konkuk University   (South Korea)

^b Konkuk University Hospital   (South Korea)

^c Dongduk Women's University   (South Korea)

Author keywords

apoptosis; benzochalcone; caspase; G2 M arrest; tubulin

Indexed keywords

BENZOCHALCONE; CASPASES; G2/M ARREST; HUMAN SOLID TUMOR CELL LINES; INHIBITION OF TUMOR GROWTH; POLY(ADP-RIBOSE) POLYMERASE; TUBULIN; TUBULIN POLYMERIZATION;

CELL CULTURE; CELL PROLIFERATION; DRUG PRODUCTS; POLYMERIZATION; TUMORS;

CELL DEATH;

CHALCONE; GROWTH INHIBITOR; TUBULIN;

ANIMAL; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; HUMAN; METABOLISM; MITOSIS; MOUSE; NUDE MOUSE; PANCREAS TUMOR; PATHOPHYSIOLOGY; POLYMERIZATION; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONE; GROWTH INHIBITORS; HUMANS; MICE; MICE, NUDE; MITOSIS; PANCREATIC NEOPLASMS; POLYMERIZATION; TUBULIN;

EID: 84891479011     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf4034688     Document Type: Article

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