Accumulation of cyclin B1, activation of cyclin B1-dependent kinase and induction of programmed cell death in human epidermoid carcinoma KB cells treated with taxol

International Journal of Cancer

Volumn 75, Issue 6, 1998, Pages 925-932

  Ling, Yi He ^a   Consoli, Ugo ^a   Tornos, Carmen ^a   Andreeff, Michael ^a   Perez Soler, Roman ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURINTRICARBOXYLIC ACID; CYCLIN B; CYCLIN DEPENDENT KINASE; CYCLOHEXIMIDE; DACTINOMYCIN; DNA FRAGMENT; ENDONUCLEASE; HISTONE H1; PACLITAXEL; PROTEIN SYNTHESIS INHIBITOR; ZINC;

APOPTOSIS; ARTICLE; CELL STRAIN KB; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CDC28 PROTEIN KINASE, S CEREVISIAE; CYCLIN B; ENZYME INHIBITORS; HUMANS; MITOSIS; PACLITAXEL; PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITORS; TUMOR CELLS, CULTURED; ZINC;

EID: 0031893985     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980316)75:6<925::AID-IJC16>3.0.CO;2-1     Document Type: Article

References (28)

1. BLAGOSKLONNY, M.V., SCHULTE, T., NGUYEN, P., TREPEL, J. and NECKERS, L.M., Taxol-induced apoptosis and phosphorylation of bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway. Cancer Res., 56, 1851-1854 (1996).
2. cdc2 coincident with taxol-induced apoptosis. Cell Growth Differ., 5, 1041-1050 (1994).
3. DRAETTA, G., Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation. Trends biochem. Sci., 15, 378-383 (1990).
4. GLOTZER, M., MURRAY, A.W. and KIRSCHNER, M.W., Cyclin is degraded by the ubiquitin pathway. Nature (Lond.), 349, 132-138 (1991).
5. GORBSKY, G.J., Kinetochores, microtubules and the metaphase checkpoint. Trends Cell Biol. 5, 143-148 (1995).
6. HARTWELL, L.H. and WEINERT, T.A., Checkpoints: controls that ensure the order of cell cycle events. Science (Wash.), 246, 629-643 (1989).
7. HOLMES, F.A., WALTERS, R.S., THERIAULT, R.L., FORMAN, A.D., NEWTON, L.K., RABER, M.N., BUZDAR, A.N., FRYE, D.K. and HORTOBAGYI, G.N., Phase II trial of taxol, an active drug in the treatment of metastatic breast cancer. J. nat. Cancer Inst., 83, 1797-1805 (1991).
8. HUNT, T., LUCA, F.C. and RUDERMAN, J.V., The requirements for protein synthesis and degradation, and control of destruction of cyclin A and B in the meiotic and mitotic cell cycles of the clam embryo. J. Cell Biol., 116, 707-724 (1992).
9. INOUYE, M., TAMARU, M. and KAMEYAMA, Y., Effect of cycloheximide and actinomycin D on radiation-induced apoptotic cell death in the developing mouse cerebellum. Int. J. Rad. Biol., 61, 669-674 (1992).
10. KING, K.L. and CIDLOWSKI, J.A., Cell cycle and apoptosis: common pathways to life and death. J. cell. Biochem., 58, 175-180 (1995).
11. KING, R.W., JACKSON, P.K. and KIRSCHNER, M.W., Mitosis in transition. Cell, 79, 563-571 (1994).
12. KROEMER, G., PETIT, P., ZAMZAMI, N., VAYSSIÉRE, J.-L. and MIGNOTTE, B., The biochemistry of programmed cell death. FASEB J., 9, 1277-1287 (1995).
13. cdc2/cyclin B1 activity induced by doxorubicin in synchronized P388 cells. Mol. Pharmacol., 49, 832-841 (1996).
14. cdc2 kinase activity, and enhancement of cdc2/cyclin B accumulation by vinblastine, nocodazole, and taxol. Proc. Amer. Ass. Cancer Res., 36, 2708 (1995).
15. 2 arrest in Chinese hamster ovary cells. Cancer Res., 50, 3761-3766 (1990).
16. MCGUIRE, W.P., ROWINSKY, E.K., ROSENHEIM, N.B., GRUMBINE, F.C., ETTINGER, D.S., AMSTRONG, D.K. and DONEHOWER, R.C., Taxol: a unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms. Ann. intern. Med., 111, 273-279 (1989).
17. MEIKRANTZ, W., GISSELBRECHT, S., TAM, S.W. and SCHLEGEL, R., Activation of cyclin A-dependent protein kinase during apoptosis. Proc. nat. Acad. Sci. (Wash.), 91, 3754-3758 (1994).
18. MURRAY, A., Cyclin ubiquitination: the destructive end of mitosis. Cell, 81, 149-152 (1995).
19. 1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei. J. Immunol., 154, 3788-3795 (1995).
20. NURSE, P., Universal control mechanism regulation onset of M-phase. Nature (Lond.), 54, 503-508 (1990).
21. 2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently. J. biol. Chem., 268, 8298-8308 (1993).
22. PETER, M., NAKAGAWA, J., DORÉE, M., LABBÉ, J.C. and NIGG, E.A., In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase. Cell, 61, 591-602 (1990).
23. cdc2. Cell, 58, 833-846 (1989).
24. 1→S transition of mammalian cells. J. cell. Biochem., 54, 379-386 (1994).
25. cdc2 activation required for apoptosis. Science (Wash.), 263, 1143-1145 (1994).
26. SOLARY, E., BERTRAND, R. and POMMIER, Y. Apoptosis induced by DNA topoisomerase I and II inhibitors in human leukemic HL-60 cells. Leukemia Lymphoma, 15, 21-32 (1994).
27. cdc2/cyclin B. Cancer Res., 52, 1823-1829 (1992).
28. WILLIAMS, G.T. and SMITH, C. A., Molecular regulation of apoptosis: genetic controls on cell death. Cell, 74, 777-779 (1993).