-
1
-
-
20044387026
-
IKK-beta links inflammation to obesity-induced insulin resistance
-
doi:10.1038/nm1185
-
Arkan, M.C., A.L. Hevener, F.R. Greten, S. Maeda, Z.W. Li, J.M. Long, A. Wynshaw-Boris, G. Poli, J. Olefsky, and M. Karin. 2005. IKK-beta links inflammation to obesity-induced insulin resistance. Nat. Med. 11:191-198. doi:10.1038/nm1185
-
(2005)
Nat. Med
, vol.11
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.W.5
Long, J.M.6
Wynshaw-Boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
-
2
-
-
34547728312
-
Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior
-
doi:10.1126/science.1142883
-
Auffray, C., D. Fogg, M. Garfa, G. Elain, O. Join-Lambert, S. Kayal, S. Sarnacki, A. Cumano, G. Lauvau, and F. Geissmann. 2007. Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science. 317:666-670. doi:10.1126/science.1142883
-
(2007)
Science
, vol.317
, pp. 666-670
-
-
Auffray, C.1
Fogg, D.2
Garfa, M.3
Elain, G.4
Join-Lambert, O.5
Kayal, S.6
Sarnacki, S.7
Cumano, A.8
Lauvau, G.9
Geissmann, F.10
-
3
-
-
0034648794
-
CAP defines a second signalling pathway required for insulin-stimulated glucose transport
-
doi:10.1038/35025089
-
Baumann, C.A., V. Ribon, M. Kanzaki, D.C. Thurmond, S. Mora, S. Shigematsu, P.E. Bickel, J.E. Pessin, and A.R. Saltiel. 2000. CAP defines a second signalling pathway required for insulin-stimulated glucose transport. Nature. 407:202-207. doi:10.1038/35025089
-
(2000)
Nature
, vol.407
, pp. 202-207
-
-
Baumann, C.A.1
Ribon, V.2
Kanzaki, M.3
Thurmond, D.C.4
Mora, S.5
Shigematsu, S.6
Bickel, P.E.7
Pessin, J.E.8
Saltiel, A.R.9
-
4
-
-
34547492488
-
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
-
doi:10.1016/j.cmet. 2007.06.010
-
Bouhlel, M.A., B. Derudas, E. Rigamonti, R. Dièvart, J. Brozek, S. Haulon, C. Zawadzki, B. Jude, G. Torpier, N. Marx, et al. 2007. PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab. 6:137-143. doi:10.1016/j.cmet. 2007.06.010
-
(2007)
Cell Metab
, vol.6
, pp. 137-143
-
-
Bouhlel, M.A.1
Derudas, B.2
Rigamonti, E.3
Dièvart, R.4
Brozek, J.5
Haulon, S.6
Zawadzki, C.7
Jude, B.8
Torpier, G.9
Marx, N.10
-
5
-
-
39549122799
-
Remodeling phenotype of human subcutaneous adipose tissue macrophages
-
doi:10.1161/CIRCULATIONAHA. 107.724096
-
Bourlier, V., A. Zakaroff-Girard, A. Miranville, S. De Barros, M. Maumus, C. Sengenes, J. Galitzky, M. Lafontan, F. Karpe, K.N. Frayn, and A. Bouloumié. 2008. Remodeling phenotype of human subcutaneous adipose tissue macrophages. Circulation. 117:806-815. doi:10.1161/CIRCULATIONAHA. 107.724096
-
(2008)
Circulation
, vol.117
, pp. 806-815
-
-
Bourlier, V.1
Zakaroff-Girard, A.2
Miranville, A.3
De Barros, S.4
Maumus, M.5
Sengenes, C.6
Galitzky, J.7
Lafontan, M.8
Karpe, F.9
Frayn, K.N.10
Bouloumié, A.11
-
6
-
-
2942721674
-
ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance
-
doi:10.1038/ni1050
-
Brint, E.K., D. Xu, H. Liu, A. Dunne, A.N. McKenzie, L.A. O'Neill, and F.Y. Liew. 2004. ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat. Immunol. 5:373-379. doi:10.1038/ni1050
-
(2004)
Nat. Immunol
, vol.5
, pp. 373-379
-
-
Brint, E.K.1
Xu, D.2
Liu, H.3
Dunne, A.4
McKenzie, A.N.5
O'Neill, L.A.6
Liew, F.Y.7
-
7
-
-
34547469630
-
Macrophage polarization and insulin resistance: PPARgamma in control
-
doi:10.1016/j.cmet.2007.07.006
-
Charo, I.F. 2007. Macrophage polarization and insulin resistance: PPARgamma in control. Cell Metab. 6:96-98. doi:10.1016/j.cmet.2007.07.006
-
(2007)
Cell Metab
, vol.6
, pp. 96-98
-
-
Charo, I.F.1
-
8
-
-
27444437321
-
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
-
doi:10.1194/jlr.M500294-JLR200
-
Cinti, S., G. Mitchell, G. Barbatelli, I. Murano, E. Ceresi, E. Faloia, S. Wang, M. Fortier, A.S. Greenberg, and M.S. Obin. 2005. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J. Lipid Res. 46:2347-2355. doi:10.1194/jlr.M500294-JLR200
-
(2005)
J. Lipid Res
, vol.46
, pp. 2347-2355
-
-
Cinti, S.1
Mitchell, G.2
Barbatelli, G.3
Murano, I.4
Ceresi, E.5
Faloia, E.6
Wang, S.7
Fortier, M.8
Greenberg, A.S.9
Obin, M.S.10
-
9
-
-
58149476609
-
Impact of macrophage toll-like receptor 4 deficiency on macrophage infiltration into adipose tissue and the artery wall in mice
-
doi:10.1007/s00125-008-1221-7
-
Coenen, K.R., M.L. Gruen, R.S. Lee-Young, M.J. Puglisi, D.H. Wasserman, and A.H. Hasty. 2009. Impact of macrophage toll-like receptor 4 deficiency on macrophage infiltration into adipose tissue and the artery wall in mice. Diabetologia. 52:318-328. doi:10.1007/s00125-008-1221-7
-
(2009)
Diabetologia
, vol.52
, pp. 318-328
-
-
Coenen, K.R.1
Gruen, M.L.2
Lee-Young, R.S.3
Puglisi, M.J.4
Wasserman, D.H.5
Hasty, A.H.6
-
10
-
-
0034880752
-
Pro-inflammatory cytokines and adipose tissue
-
doi:10.1079/PNS2001110
-
Coppack, S.W. 2001. Pro-inflammatory cytokines and adipose tissue. Proc. Nutr. Soc. 60:349-356. doi:10.1079/PNS2001110
-
(2001)
Proc. Nutr. Soc
, vol.60
, pp. 349-356
-
-
Coppack, S.W.1
-
11
-
-
67651083733
-
Reactive oxygen species production is increased in the peripheral blood monocytes of obese patients
-
Degasperi, G.R., R.G. Denis, J. Morari, C. Solon, B. Geloneze, C. Stabe, J.C. Pareja, A.E. Vercesi, and L.A. Velloso. 2009. Reactive oxygen species production is increased in the peripheral blood monocytes of obese patients. Metabolism. 58:1087-1095.
-
(2009)
Metabolism
, vol.58
, pp. 1087-1095
-
-
Degasperi, G.R.1
Denis, R.G.2
Morari, J.3
Solon, C.4
Geloneze, B.5
Stabe, C.6
Pareja, J.C.7
Vercesi, A.E.8
Velloso, L.A.9
-
12
-
-
33751511978
-
The dermal microenvironment induces the expression of the alternative activation marker CD301/mMGL in mononuclear phagocytes, independent of IL-4/IL-13 signaling
-
doi:10.1189/jlb. 1005564
-
Dupasquier, M., P. Stoitzner, H. Wan, D. Cerqueira, A. van Oudenaren, J.S. Voerman, K. Denda-Nagai, T. Irimura, G. Raes, N. Romani, and P.J. Leenen. 2006. The dermal microenvironment induces the expression of the alternative activation marker CD301/mMGL in mononuclear phagocytes, independent of IL-4/IL-13 signaling. J. Leukoc. Biol. 80:838-849. doi:10.1189/jlb. 1005564
-
(2006)
J. Leukoc. Biol
, vol.80
, pp. 838-849
-
-
Dupasquier, M.1
Stoitzner, P.2
Wan, H.3
Cerqueira, D.4
van Oudenaren, A.5
Voerman, J.S.6
Denda-Nagai, K.7
Irimura, T.8
Raes, G.9
Romani, N.10
Leenen, P.J.11
-
13
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
doi:10.1038/nm.2002
-
Feuerer, M., L. Herrero, D. Cipolletta, A. Naaz, J. Wong, A. Nayer, J. Lee, A.B. Goldfine, C. Benoist, S. Shoelson, and D. Mathis. 2009. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat. Med. 15:930-939. doi:10.1038/nm.2002
-
(2009)
Nat. Med
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
Naaz, A.4
Wong, J.5
Nayer, A.6
Lee, J.7
Goldfine, A.B.8
Benoist, C.9
Shoelson, S.10
Mathis, D.11
-
14
-
-
0037963473
-
Blood monocytes consist of two principal subsets with distinct migratory properties
-
doi:10.1016/S1074-7613(03)00174-2
-
Geissmann, F., S. Jung, and D.R. Littman. 2003. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity. 19:71-82. doi:10.1016/S1074-7613(03)00174-2
-
(2003)
Immunity
, vol.19
, pp. 71-82
-
-
Geissmann, F.1
Jung, S.2
Littman, D.R.3
-
15
-
-
4644338458
-
Circulating mononuclear cells in the obese are in a proinflammatory state
-
doi:10.1161/01. CIR.0000142055.53122.FA
-
Ghanim, H., A. Aljada, D. Hofmeyer, T. Syed, P. Mohanty, and P. Dandona. 2004. Circulating mononuclear cells in the obese are in a proinflammatory state. Circulation. 110:1564-1571. doi:10.1161/01. CIR.0000142055.53122.FA
-
(2004)
Circulation
, vol.110
, pp. 1564-1571
-
-
Ghanim, H.1
Aljada, A.2
Hofmeyer, D.3
Syed, T.4
Mohanty, P.5
Dandona, P.6
-
16
-
-
33845975254
-
Macrophage heterogeneity and tissue lipids
-
doi:10.1172/JCI30992
-
Gordon, S. 2007. Macrophage heterogeneity and tissue lipids. J. Clin. Invest. 117:89-93. doi:10.1172/JCI30992
-
(2007)
J. Clin. Invest
, vol.117
, pp. 89-93
-
-
Gordon, S.1
-
17
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
doi:10.1038/nri1733
-
Gordon, S., and P.R. Taylor. 2005. Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5:953-964. doi:10.1038/nri1733
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
-
18
-
-
34249907880
-
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
-
doi:10.1172/JCI31561
-
Hevener, A.L., J.M. Olefsky, D. Reichart, M.T. Nguyen, G. Bandyopadyhay, H.Y. Leung, M.J. Watt, C. Benner, M.A. Febbraio, A.K. Nguyen, et al. 2007. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J. Clin. Invest. 117:1658-1669. doi:10.1172/JCI31561
-
(2007)
J. Clin. Invest
, vol.117
, pp. 1658-1669
-
-
Hevener, A.L.1
Olefsky, J.M.2
Reichart, D.3
Nguyen, M.T.4
Bandyopadyhay, G.5
Leung, H.Y.6
Watt, M.J.7
Benner, C.8
Febbraio, M.A.9
Nguyen, A.K.10
-
19
-
-
33845866857
-
Inflammation and metabolic disorders
-
doi:10.1038/nature05485
-
Hotamisligil, G.S. 2006. Inflammation and metabolic disorders. Nature. 444:860-867. doi:10.1038/nature05485
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
20
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
-
doi:10.1172/JCI117936
-
Hotamisligil, G.S., P. Arner, J.F. Caro, R.L. Atkinson, and B.M. Spiegelman. 1995. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J. Clin. Invest. 95:2409-2415. doi:10.1172/JCI117936
-
(1995)
J. Clin. Invest
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
21
-
-
34548434020
-
Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue
-
doi:10.2337/db07-0425
-
Inouye, K.E., H. Shi, J.K. Howard, C.H. Daly, G.M. Lord, B.J. Rollins, and J.S. Flier. 2007. Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue. Diabetes. 56:2242-2250. doi:10.2337/db07-0425
-
(2007)
Diabetes
, vol.56
, pp. 2242-2250
-
-
Inouye, K.E.1
Shi, H.2
Howard, J.K.3
Daly, C.H.4
Lord, G.M.5
Rollins, B.J.6
Flier, J.S.7
-
22
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
doi:10.1172/JCI26498
-
Kanda, H., S. Tateya, Y. Tamori, K. Kotani, K. Hiasa, R. Kitazawa, S. Kitazawa, H. Miyachi, S. Maeda, K. Egashira, and M. Kasuga. 2006. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J. Clin. Invest. 116:1494-1505. doi:10.1172/JCI26498
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
Kotani, K.4
Hiasa, K.5
Kitazawa, R.6
Kitazawa, S.7
Miyachi, H.8
Maeda, S.9
Egashira, K.10
Kasuga, M.11
-
23
-
-
44349112305
-
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity
-
doi:10.1016/j.cmet.2008.04.002
-
Kang, K., S.M. Reilly, V. Karabacak, M.R. Gangl, K. Fitzgerald, B. Hatano, and C.H. Lee. 2008. Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab. 7:485-495. doi:10.1016/j.cmet.2008.04.002
-
(2008)
Cell Metab
, vol.7
, pp. 485-495
-
-
Kang, K.1
Reilly, S.M.2
Karabacak, V.3
Gangl, M.R.4
Fitzgerald, K.5
Hatano, B.6
Lee, C.H.7
-
24
-
-
34848872799
-
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
-
doi:10.1172/JCI31021
-
Kim, J.Y., E. van de Wall, M. Laplante, A. Azzara, M.E. Trujillo, S.M. Hofmann, T. Schraw, J.L. Durand, H. Li, G. Li, et al. 2007. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J. Clin. Invest. 117:2621-2637. doi:10.1172/JCI31021
-
(2007)
J. Clin. Invest
, vol.117
, pp. 2621-2637
-
-
Kim, J.Y.1
van de Wall, E.2
Laplante, M.3
Azzara, A.4
Trujillo, M.E.5
Hofmann, S.M.6
Schraw, T.7
Durand, J.L.8
Li, H.9
Li, G.10
-
25
-
-
48449102722
-
MCP-1 deficiency fails to restrain macrophage infiltration into adipose tissue
-
doi:10.2337/db07-1061
-
Kirk, E.A., Z.K. Sagawa, T.O. McDonald, K.D. O'Brien, and J.W. Heinecke. 2008. MCP-1 deficiency fails to restrain macrophage infiltration into adipose tissue. Diabetes. 57:1254-1261. doi:10.2337/db07-1061
-
(2008)
Diabetes
, vol.57
, pp. 1254-1261
-
-
Kirk, E.A.1
Sagawa, Z.K.2
McDonald, T.O.3
O'Brien, K.D.4
Heinecke, J.W.5
-
26
-
-
10344248202
-
Identification of sialoadhesin as a dominant lymph node counter-receptor for mouse macrophage galactose-type C-type lectin 1
-
doi:10.1074/jbc.M409300200
-
Kumamoto, Y., N. Higashi, K. Denda-Nagai, M. Tsuiji, K. Sato, P.R. Crocker, and T. Irimura. 2004. Identification of sialoadhesin as a dominant lymph node counter-receptor for mouse macrophage galactose-type C-type lectin 1. J. Biol. Chem. 279:49274-49280. doi:10.1074/jbc.M409300200
-
(2004)
J. Biol. Chem
, vol.279
, pp. 49274-49280
-
-
Kumamoto, Y.1
Higashi, N.2
Denda-Nagai, K.3
Tsuiji, M.4
Sato, K.5
Crocker, P.R.6
Irimura, T.7
-
27
-
-
59649092443
-
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival
-
doi:10.1182/blood-2008-07-170787
-
Landsman, L., L. Bar-On, A. Zernecke, K.W. Kim, R. Krauthgamer, E. Shagdarsuren, S.A. Lira, I.L. Weissman, C. Weber, and S. Jung. 2009. CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood. 113:963-972. doi:10.1182/blood-2008-07-170787
-
(2009)
Blood
, vol.113
, pp. 963-972
-
-
Landsman, L.1
Bar-On, L.2
Zernecke, A.3
Kim, K.W.4
Krauthgamer, R.5
Shagdarsuren, E.6
Lira, S.A.7
Weissman, I.L.8
Weber, C.9
Jung, S.10
-
28
-
-
0141756182
-
Glycan-dependent leukocyte adhesion and recruitment in inflammation
-
doi:10.1016/j.ceb.2003. 08.002
-
Lowe, J.B. 2003. Glycan-dependent leukocyte adhesion and recruitment in inflammation. Curr. Opin. Cell Biol. 15:531-538. doi:10.1016/j.ceb.2003. 08.002
-
(2003)
Curr. Opin. Cell Biol
, vol.15
, pp. 531-538
-
-
Lowe, J.B.1
-
29
-
-
33846004396
-
Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
-
doi:10.1152/ajpendo.00284.2006
-
Lumeng, C.N., S.M. Deyoung, and A.R. Saltiel. 2007a. Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins. Am. J. Physiol. Endocrinol. Metab. 292:E166-E174. doi:10.1152/ajpendo.00284.2006
-
(2007)
Am. J. Physiol. Endocrinol. Metab
, vol.292
-
-
Lumeng, C.N.1
Deyoung, S.M.2
Saltiel, A.R.3
-
30
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
doi:10.1172/JCI29881
-
Lumeng, C.N., J.L. Bodzin, and A.R. Saltiel. 2007b. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Invest. 117:175-184. doi:10.1172/JCI29881
-
(2007)
J. Clin. Invest
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
31
-
-
58149347227
-
Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
-
doi:10.2337/db08-0872
-
Lumeng, C.N., J.B. DelProposto, D.J. Westcott, and A.R. Saltiel. 2008. Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes. 57:3239-3246. doi:10.2337/db08-0872
-
(2008)
Diabetes
, vol.57
, pp. 3239-3246
-
-
Lumeng, C.N.1
DelProposto, J.B.2
Westcott, D.J.3
Saltiel, A.R.4
-
32
-
-
14044262905
-
Regulation of PSGL-1 interactions with L-selectin, P-selectin, and E-selectin: Role of human fucosyltransferase-IV and -VII
-
doi:10.1074/jbc.M410899200
-
Martinez, M., M. Joffraud, S. Giraud, B. Baïsse, M.P. Bernimoulin, M. Schapira, and O. Spertini. 2005. Regulation of PSGL-1 interactions with L-selectin, P-selectin, and E-selectin: role of human fucosyltransferase-IV and -VII. J. Biol. Chem. 280:5378-5390. doi:10.1074/jbc.M410899200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 5378-5390
-
-
Martinez, M.1
Joffraud, M.2
Giraud, S.3
Baïsse, B.4
Bernimoulin, M.P.5
Schapira, M.6
Spertini, O.7
-
33
-
-
50949108719
-
Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
-
doi:10.1194/jlr.M800019-JLR200
-
Murano, I., G. Barbatelli, V. Parisani, C. Latini, G. Muzzonigro, M. Castellucci, and S. Cinti. 2008. Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice. J. Lipid Res. 49:1562-1568. doi:10.1194/jlr.M800019-JLR200
-
(2008)
J. Lipid Res
, vol.49
, pp. 1562-1568
-
-
Murano, I.1
Barbatelli, G.2
Parisani, V.3
Latini, C.4
Muzzonigro, G.5
Castellucci, M.6
Cinti, S.7
-
34
-
-
31044447347
-
Inflamed fat: What starts the fire?
-
doi:10.1172/JCI27280
-
Neels, J.G., and J.M. Olefsky. 2006. Inflamed fat: what starts the fire? J. Clin. Invest. 116:33-35. doi:10.1172/JCI27280
-
(2006)
J. Clin. Invest
, vol.116
, pp. 33-35
-
-
Neels, J.G.1
Olefsky, J.M.2
-
35
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
-
doi:10.1074/jbc.M706762200
-
Nguyen, M.T., S. Favelyukis, A.K. Nguyen, D. Reichart, P.A. Scott, A. Jenn, R. Liu-Bryan, C.K. Glass, J.G. Neels, and J.M. Olefsky. 2007. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J. Biol. Chem. 282:35279-35292. doi:10.1074/jbc.M706762200
-
(2007)
J. Biol. Chem
, vol.282
, pp. 35279-35292
-
-
Nguyen, M.T.1
Favelyukis, S.2
Nguyen, A.K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-Bryan, R.7
Glass, C.K.8
Neels, J.G.9
Olefsky, J.M.10
-
36
-
-
38849118568
-
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue
-
Nishimura, S., I. Manabe, M. Nagasaki, K. Seo, H. Yamashita, Y. Hosoya, M. Ohsugi, K. Tobe, T. Kadowaki, R. Nagai, and S. Sugiura. 2008. In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue. J. Clin. Invest. 118:710-721.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 710-721
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Seo, K.4
Yamashita, H.5
Hosoya, Y.6
Ohsugi, M.7
Tobe, K.8
Kadowaki, T.9
Nagai, R.10
Sugiura, S.11
-
37
-
-
34347354309
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
-
doi:10.1038/nature05894
-
Odegaard, J.I., R.R. Ricardo-Gonzalez, M.H. Goforth, C.R. Morel, V. Subramanian, L. Mukundan, A. Red Eagle, D. Vats, F. Brombacher, A.W. Ferrante, and A. Chawla. 2007. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature. 447:1116-1120. doi:10.1038/nature05894
-
(2007)
Nature
, vol.447
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Red Eagle, A.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
38
-
-
0034747132
-
-
Poland, D.C., C.G. Schalkwijk, C.D. Stehouwer, C.A. Koeleman, B. van het Hof, and W. van Dijk. 2001. Increased alpha3-fucosylation of alpha1-acid glycoprotein in Type I diabetic patients is related to vascular function. Glycoconj. J. 18:261-268. doi:10.1023/A:1012412908983
-
Poland, D.C., C.G. Schalkwijk, C.D. Stehouwer, C.A. Koeleman, B. van het Hof, and W. van Dijk. 2001. Increased alpha3-fucosylation of alpha1-acid glycoprotein in Type I diabetic patients is related to vascular function. Glycoconj. J. 18:261-268. doi:10.1023/A:1012412908983
-
-
-
-
39
-
-
58249112154
-
A C-type lectin MGL1/CD301a plays an anti-inflammatory role in murine experimental colitis
-
doi:10.2353/ajpath.2009.080235
-
Saba, K., K. Denda-Nagai, and T. Irimura. 2009. A C-type lectin MGL1/CD301a plays an anti-inflammatory role in murine experimental colitis. Am. J. Pathol. 174:144-152. doi:10.2353/ajpath.2009.080235
-
(2009)
Am. J. Pathol
, vol.174
, pp. 144-152
-
-
Saba, K.1
Denda-Nagai, K.2
Irimura, T.3
-
40
-
-
0038809142
-
Monocyte chemoattractant protein 1 in obesity and insulin resistance
-
doi:10.1073/pnas.1133870100
-
Sartipy, P., and D.J. Loskutoff. 2003. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc. Natl. Acad. Sci. USA. 100:7265-7270. doi:10.1073/pnas.1133870100
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7265-7270
-
-
Sartipy, P.1
Loskutoff, D.J.2
-
41
-
-
33645902493
-
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
-
doi:10.1038/ni1309
-
Serbina, N.V., and E.G. Pamer. 2006. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat. Immunol. 7:311-317. doi:10.1038/ni1309
-
(2006)
Nat. Immunol
, vol.7
, pp. 311-317
-
-
Serbina, N.V.1
Pamer, E.G.2
-
42
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
doi:10.1172/JCI28898
-
Shi, H., M.V. Kokoeva, K. Inouye, I. Tzameli, H. Yin, and J.S. Flier. 2006. TLR4 links innate immunity and fatty acid-induced insulin resistance. J. Clin. Invest. 116:3015-3025. doi:10.1172/JCI28898
-
(2006)
J. Clin. Invest
, vol.116
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
43
-
-
60949086137
-
Characterization of murine MGL1 and MGL2 C-type lectins: Distinct glycan specificities and tumor binding properties
-
doi:10.1016/j.molimm.2008.11.021
-
Singh, S.K., I. Streng-Ouwehand, M. Litjens, D.R. Weelij, J.J. García-Vallejo, S.J. van Vliet, E. Saeland, and Y. van Kooyk. 2009. Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties. Mol. Immunol. 46:1240-1249. doi:10.1016/j.molimm.2008.11.021
-
(2009)
Mol. Immunol
, vol.46
, pp. 1240-1249
-
-
Singh, S.K.1
Streng-Ouwehand, I.2
Litjens, M.3
Weelij, D.R.4
García-Vallejo, J.J.5
van Vliet, S.J.6
Saeland, E.7
van Kooyk, Y.8
-
44
-
-
35548943962
-
JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity
-
doi:10.1016/j.cmet.2007.09.011
-
Solinas, G., C. Vilcu, J.G. Neels, G.K. Bandyopadhyay, J.L. Luo, W. Naugler, S. Grivennikov, A. Wynshaw-Boris, M. Scadeng, J.M. Olefsky, and M. Karin. 2007. JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity. Cell Metab. 6:386-397. doi:10.1016/j.cmet.2007.09.011
-
(2007)
Cell Metab
, vol.6
, pp. 386-397
-
-
Solinas, G.1
Vilcu, C.2
Neels, J.G.3
Bandyopadhyay, G.K.4
Luo, J.L.5
Naugler, W.6
Grivennikov, S.7
Wynshaw-Boris, A.8
Scadeng, M.9
Olefsky, J.M.10
Karin, M.11
-
45
-
-
0344443732
-
Adiposity elevates plasma MCP-1 levels leading to the increased CD11b-positive monocytes in mice
-
doi:10.1074/jbc.M309895200
-
Takahashi, K., S. Mizuarai, H. Araki, S. Mashiko, A. Ishihara, A. Kanatani, H. Itadani, and H. Kotani. 2003. Adiposity elevates plasma MCP-1 levels leading to the increased CD11b-positive monocytes in mice. J. Biol. Chem. 278:46654-46660. doi:10.1074/jbc.M309895200
-
(2003)
J. Biol. Chem
, vol.278
, pp. 46654-46660
-
-
Takahashi, K.1
Mizuarai, S.2
Araki, H.3
Mashiko, S.4
Ishihara, A.5
Kanatani, A.6
Itadani, H.7
Kotani, H.8
-
46
-
-
34147164049
-
Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites
-
doi:10.1172/JCI29919
-
Tsou, C.L., W. Peters, Y. Si, S. Slaymaker, A.M. Aslanian, S.P. Weisberg, M. Mack, and I.F. Charo. 2007. Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J. Clin. Invest. 117:902-909. doi:10.1172/JCI29919
-
(2007)
J. Clin. Invest
, vol.117
, pp. 902-909
-
-
Tsou, C.L.1
Peters, W.2
Si, Y.3
Slaymaker, S.4
Aslanian, A.M.5
Weisberg, S.P.6
Mack, M.7
Charo, I.F.8
-
47
-
-
0037047438
-
Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1
-
doi:10.1074/jbc.M203774200
-
Tsuiji, M., M. Fujimori, Y. Ohashi, N. Higashi, T.M. Onami, S.M. Hedrick, and T. Irimura. 2002. Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1. J. Biol. Chem. 277:28892-28901. doi:10.1074/jbc.M203774200
-
(2002)
J. Biol. Chem
, vol.277
, pp. 28892-28901
-
-
Tsuiji, M.1
Fujimori, M.2
Ohashi, Y.3
Higashi, N.4
Onami, T.M.5
Hedrick, S.M.6
Irimura, T.7
-
48
-
-
59149106509
-
C-type lectins on dendritic cells: Key modulators for the induction of immune responses
-
doi:10.1042/BST0361478
-
van Kooyk, Y. 2008. C-type lectins on dendritic cells: key modulators for the induction of immune responses. Biochem. Soc. Trans. 36:1478-1481. doi:10.1042/BST0361478
-
(2008)
Biochem. Soc. Trans
, vol.36
, pp. 1478-1481
-
-
van Kooyk, Y.1
-
49
-
-
33750126191
-
Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45
-
doi:10.1038/ni1390
-
van Vliet, S.J., S.I. Gringhuis, T.B. Geijtenbeek, and Y. van Kooyk. 2006. Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45. Nat. Immunol. 7:1200-1208. doi:10.1038/ni1390
-
(2006)
Nat. Immunol
, vol.7
, pp. 1200-1208
-
-
van Vliet, S.J.1
Gringhuis, S.I.2
Geijtenbeek, T.B.3
van Kooyk, Y.4
-
50
-
-
38749105791
-
Sweet preferences of MGL: Carbohydrate specificity and function
-
doi:10.1016/j.it.2007.10.010
-
van Vliet, S.J., E. Saeland, and Y. van Kooyk. 2008a. Sweet preferences of MGL: carbohydrate specificity and function. Trends Immunol. 29:83-90. doi:10.1016/j.it.2007.10.010
-
(2008)
Trends Immunol
, vol.29
, pp. 83-90
-
-
van Vliet, S.J.1
Saeland, E.2
van Kooyk, Y.3
-
51
-
-
51549119171
-
The C-type lectin macrophage galactose-type lectin impedes migration of immature APCs
-
van Vliet, S.J., L.C. Paessens, V.C. Broks-van den Berg, T.B. Geijtenbeek, and Y. van Kooyk. 2008b. The C-type lectin macrophage galactose-type lectin impedes migration of immature APCs. J. Immunol. 181:3148-3155.
-
(2008)
J. Immunol
, vol.181
, pp. 3148-3155
-
-
van Vliet, S.J.1
Paessens, L.C.2
Broks-van den Berg, V.C.3
Geijtenbeek, T.B.4
van Kooyk, Y.5
-
52
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg, S.P., D. McCann, M. Desai, M. Rosenbaum, R.L. Leibel, and A.W. Ferrante Jr. 2003. Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112:1796-1808.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
53
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
doi:10.1172/JCI24335
-
Weisberg, S.P., D. Hunter, R. Huber, J. Lemieux, S. Slaymaker, K. Vaddi, I. Charo, R.L. Leibel, and A.W. Ferrante Jr. 2006. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J. Clin. Invest. 116:115-124. doi:10.1172/JCI24335
-
(2006)
J. Clin. Invest
, vol.116
, pp. 115-124
-
-
Weisberg, S.P.1
Hunter, D.2
Huber, R.3
Lemieux, J.4
Slaymaker, S.5
Vaddi, K.6
Charo, I.7
Leibel, R.L.8
Ferrante Jr., A.W.9
-
54
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu, H., G.T. Barnes, Q. Yang, G. Tan, D. Yang, C.J. Chou, J. Sole, A. Nichols, J.S. Ross, L.A. Tartaglia, and H. Chen. 2003. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112:1821-1830.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
55
-
-
28444431967
-
Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos
-
doi:10.1093/glycob/cwj028
-
Yuita, H., M. Tsuiji, Y. Tajika, Y. Matsumoto, K. Hirano, N. Suzuki, and T. Irimura. 2005. Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos. Glycobiology. 15:1368-1375. doi:10.1093/glycob/cwj028
-
(2005)
Glycobiology
, vol.15
, pp. 1368-1375
-
-
Yuita, H.1
Tsuiji, M.2
Tajika, Y.3
Matsumoto, Y.4
Hirano, K.5
Suzuki, N.6
Irimura, T.7
-
56
-
-
34548354722
-
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive proinflammatory mediator production
-
doi:10.1038/sj.ijo.0803632
-
Zeyda, M., D. Farmer, J. Todoric, O. Aszmann, M. Speiser, G. Györi, G.J. Zlabinger, and T.M. Stulnig. 2007. Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive proinflammatory mediator production. Int J Obes (Lond). 31:1420-1428. doi:10.1038/sj.ijo.0803632
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 1420-1428
-
-
Zeyda, M.1
Farmer, D.2
Todoric, J.3
Aszmann, O.4
Speiser, M.5
Györi, G.6
Zlabinger, G.J.7
Stulnig, T.M.8
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