Oxygen regulates tissue nitrite metabolism

Antioxidants and Redox Signaling

Volumn 17, Issue 7, 2012, Pages 951-961

  Curtis, Erin ^a   Hsu, Lewis L ^a   Noguchi, Audrey C ^b   Geary, Lisa ^c   Shiva, Sruti ^c,d  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYANIDE; IRON; NITRITE; NITRITE REDUCTASE; OXYGEN; S NITROSOTHIOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; MALE; MOUSE; NITROSATION; NONHUMAN; OXIDATION; OXYGEN TENSION; OXYGENATION; PRIORITY JOURNAL; RAT; REDUCTION; REVIEW; SIGNAL TRANSDUCTION; TISSUE HOMOGENATE; TISSUE LEVEL; TISSUE METABOLISM;

ANIMALS; ELECTRON TRANSPORT COMPLEX IV; HUMANS; MITOCHONDRIA; NITRITES; OXYGEN;

MUS;

EID: 84862582904     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2011.4242     Document Type: Review

References (51)

1. Abu-Soud HM, Ichimori K, Presta A, and Stuehr DJ. Electron transfer, oxygen binding, and nitric oxide feedback inhibition in endothelial nitric-oxide synthase. J Biol Chem 275: 17349-17357, 2000. (Pubitemid 30430770)
2. Agarwal V, Kommaddi RP, Valli K, Ryder D, Hyde TM, Kleinman JE, Strobel HW, and Ravindranath V. Drug metabolism in human brain: High levels of cytochrome P4503A43 in brain and metabolism of anti-anxiety drug alprazolam to its active metabolite. PLoS One 3: e2337, 2008.
3. Alef MJ, Vallabhaneni R, Carchman E, Morris SM, Jr., Shiva S, Wang Y, Kelley EE, Tarpey MM, Gladwin MT, Tzeng E, and Zuckerbraun BS. Nitrite-generated NO circumvents dysregulated arginine/NOS signaling to protect against intimal hyperplasia in Sprague-Dawley rats. J Clin Invest 121: 1646-1656, 2011.
4. Arillo A, Melodia F, and Marsano B. Nitrite biotransformation by mitochondria from the earthworm Eisenia foetida (Savigny). Comp Biochem Physiol B 102: 209-211, 1992.
5. Bailey SJ, Winyard P, Vanhatalo A, Blackwell JR, Dimenna FJ, Wilkerson DP, Tarr J, Benjamin N, and Jones AM. Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans. J Appl Physiol 107: 1144-1155, 2009.
6. Balaban RS, Mootha VK, and Arai A. Spectroscopic determination of cytochrome c oxidase content in tissues containing myoglobin or hemoglobin. Anal Biochem 23: 274-278, 1996. (Pubitemid 26177090)
7. Basu S, Azarova NA, Font MD, King SB, Hogg N, Gladwin MT, Shiva S, and Kim-Shapiro DB. Nitrite reductase activity of cytochrome c. J Biol Chem 283: 32590-32597, 2008.
8. 3 by the concerted nitrite reductase and anhydrase activity of hemoglobin. Nat Chem Biol 3: 785-794, 2007. (Pubitemid 350126874)
9. Benamar A, Rolletschek H, Borisjuk L, Avelange-Macherel MH, Curien G, Mostefai HA, Andriantsitohaina R, and Macherel D. Nitrite-nitric oxide control of mitochondrial respiration at the frontier of anoxia. Biochim Biophys Acta 1777: 1268-1275, 2008.
10. Bosworth CA, Toledo JC, Jr., Zmijewski JW, Li Q, and Lancaster JR, Jr. Dinitrosyliron complexes and the mechanism (s) of cellular protein nitrosothiol formation from nitric oxide. Proc Natl Acad Sci USA 106: 4671-4676, 2009.
11. Bryan NS, Fernandez BO, Bauer SM, Garcia-Saura MF, Milsom AB, Rassaf T, Maloney RE, Bharti A, Rodriguez J, and Feelisch M. Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues. Nat Chem Biol 1: 290-297, 2005.
12. Cantu-Medellin N, Vitturi DA, Rodriguez C, Murphy S, Dorman S, Shiva S, Zhou Y, Jia Y, Palmer AF, and Patel RP. Effects of T-and R-state stabilization on deoxyhemoglobinnitrite reactions and stimulation of nitric oxide signaling. Nitric Oxide 25: 59-69, 2011.
13. Castello PR, David PS, McClure T, Crook Z, and Poyton RO. Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: Implications for oxygen sensing and hypoxic signaling in eukaryotes. Cell Metab 3: 277-287, 2006.
14. de Jong JW, Schoemaker RG, de Jonge R, Bernocchi P, Keijzer E, Harrison R, Sharma HS, and Ceconi C. Enhanced expression and activity of xanthine oxidoreductase in the failing heart. J Mol Cell Cardiol 32: 2083-2089, 2000.
15. de Jong JW, van der Meer P, Nieukoop AS, Huizer T, Stroeve RJ, and Bos E. Xanthine oxidoreductase activity in perfused hearts of various species, including humans. Circ Res 67: 770-773, 1990. (Pubitemid 20315004)
16. Dezfulian C, Shiva S, Alekseyenko A, Pendyal A, Beiser DG, Munasinghe JP, Anderson SA, Chesley CF, Vanden Hoek TL, and Gladwin MT. Nitrite therapy after cardiac arrest reduces reactive oxygen species generation, improves cardiac and neurological function, and enhances survival via reversible inhibition of mitochondrial complex I. Circulation 120: 897-905, 2009.
17. Doel JJ, Godber BL, Eisenthal R, and Harrison R. Reduction of organic nitrates catalysed by xanthine oxidoreductase under anaerobic conditions. Biochim Biophys Acta 1527: 81-87, 2001. (Pubitemid 32566213)
18. Doyle MP and Hoekstra JW. Oxidation of nitrogen oxides by bound dioxygen in hemoproteins. J Inorg Biochem 14: 351-358, 1981. (Pubitemid 11006175)
19. Duranski MR, Greer JJ, Dejam A, Jaganmohan S, Hogg N, Langston W, Patel RP, Yet SF, Wang X, Kevil CG, Gladwin MT, and Lefer DJ. Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. J Clin Invest 115: 1232-1240, 2005. (Pubitemid 40629041)
20. Duthu GS and Shertzer HG. Effect of nitrite on rabbit liver mixed-function oxidase activity. Drug Metab Dispos 7: 263-269, 1979. (Pubitemid 10223212)
21. Feelisch M, Fernandez BO, Bryan NS, Garcia-Saura MF, Bauer S, Whitlock DR, Ford PC, Janero DR, Rodriguez J, and Ashrafian H. Tissue processing of nitrite in hypoxia: An intricate interplay of nitric oxide-generating and-scavenging systems. J Biol Chem 283: 33927-33934, 2008.
22. Gladwin MT, Wang X, Reiter CD, Yang BK, Vivas EX, Bonaventura C, and Schechter AN. S-Nitrosohemoglobin is unstable in the reductive erythrocyte environment and lacks O2/NO-linked allosteric function. J Biol Chem 277: 27818-27828, 2002. (Pubitemid 34966727)
23. Gonzalez FM, Shiva S, Vincent PS, Ringwood LA, Hsu LY, Hon YY, Aletras AH, Cannon RO, 3rd, Gladwin MT, and Arai AE. Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction. Circulation 117: 2986-2994, 2008.
24. Grubina R, Huang Z, Shiva S, Joshi MS, Azarov I, Basu S, Ringwood LA, Jiang A, Hogg N, Kim-Shapiro DB, and Gladwin MT. Concerted nitric oxide formation and release from the simultaneous reactions of nitrite with deoxy-and oxyhemoglobin. J Biol Chem 282: 12916-12927, 2007. (Pubitemid 47100601)
25. Hendgen-Cotta UB, Merx MW, Shiva S, Schmitz J, Becher S, Klare JP, Steinhoff HJ, Goedecke A, Schrader J, Gladwin MT, Kelm M, and Rassaf T. Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury. Proc Natl Acad Sci USA 105: 10256-10261, 2008.
26. Heppel LA and Porterfield VT. Metabolism of inorganic nitrite and nitrate esters; The coupled oxidation of nitrite by peroxide-forming systems and catalase. J Biol Chem 178: 549-556, 1949.
27. 3 formation. Chemistry 17: 6348-6358, 2011.
28. Huang KT, Keszler A, Patel N, Patel RP, Gladwin MT, Kim-Shapiro DB, and Hogg N. The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry. J Biol Chem 280: 31126-31131, 2005. (Pubitemid 41291848)
29. Huang Z, Shiva S, Kim-Shapiro DB, Patel RP, Ringwood LA, Irby CE, Huang KT, Ho C, Hogg N, Schechter AN, and Gladwin MT. Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control. J Clin Invest 115: 2099-2107, 2005. (Pubitemid 41134151)
30. Ignarro LJ, Fukuto JM, Griscavage JM, Rogers NE, and Byrns RE. Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: Comparison with enzymatically formed nitric oxide from L-arginine. Proc Natl Acad Sci USA 90: 8103-8107, 1993. (Pubitemid 23260863)
31. Jansson EA, Huang L, Malkey R, Govoni M, Nihlen C, Olsson A, Stensdotter M, Petersson J, Holm L, Weitzberg E, and Lundberg JO. A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis. Nat Chem Biol 4: 411-417, 2008. (Pubitemid 351860549)
32. Jung KH, Chu K, Ko SY, Lee ST, Sinn DI, Park DK, Kim JM, Song EC, Kim M, and Roh JK. Early intravenous infusion of sodium nitrite protects brain against in vivo ischemiareperfusion injury. Stroke 37: 2744-2750, 2006. (Pubitemid 44922536)
33. Karamanlidis G, Nascimben L, Couper GS, Shekar PS, del Monte F, and Tian R. Defective DNA replication impairs mitochondrial biogenesis in human failing hearts. Circ Res 106: 1541-1548, 2010.
34. Kim YM and Lancaster JR, Jr. Tetrahydrobiopterin-dependent nitrite oxidation to nitrate in isolated rat hepatocytes. FEBS Lett 332: 255-259, 1993. (Pubitemid 23305335)
35. Kozlov AV, Dietrich B, and Nohl H. Various intracellular compartments cooperate in the release of nitric oxide from glycerol trinitrate in liver. Br J Pharmacol 139: 989-997, 2003. (Pubitemid 36877397)
36. Kozlov AV, Staniek K, and Nohl H. Nitrite reductase activity is a novel function of mammalian mitochondria. FEBS Lett 454: 127-130, 1999. (Pubitemid 29296938)
37. Kumar D, Branch BG, Pattillo CB, Hood J, Thoma S, Simpson S, Illum S, Arora N, Chidlow JH, Jr., Langston W, Teng X, Lefer DJ, Patel RP, and Kevil CG. Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis. Proc Natl Acad Sci USA 105: 7540-7545, 2008. (Pubitemid 351830054)
38. Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, and Weitzberg E. Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metab 13: 149-159, 2011.
39. Larsen FJ, Weitzberg E, Lundberg JO, and Ekblom B. Dietary nitrate reduces maximal oxygen consumption while maintaining work performance in maximal exercise. Free Radic Biol Med 48: 342-347, 2010.
40. Li H, Cui H, Kundu TK, Alzawahra W, and Zweier JL. Nitric oxide production from nitrite occurs primarily in tissues not in the blood: Critical role of xanthine oxidase and aldehyde oxidase. J Biol Chem 283: 17855-17863, 2008.
41. Lundberg JO, Carlstrom M, Larsen FJ, and Weitzberg E. Roles of dietary inorganic nitrate in cardiovascular health and disease. Cardiovasc Res 89: 525-532, 2011.
42. Lundberg JO, Weitzberg E, and Gladwin MT. The nitratenitrite-nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov 7: 156-167, 2008. (Pubitemid 351194063)
43. Maia LB and Moura JJ. Nitrite reduction by xanthine oxidase family enzymes: A new class of nitrite reductases. J Biol Inorg Chem 16: 443-460, 2011.
44. Paitian NA, Markossian KA, and Nalbandyan RM. The effect of nitrite on cytochrome oxidase. Biochem Biophys Res Commun 133: 1104-1111, 1985.
45. Shiva S, Huang Z, Grubina R, Sun J, Ringwood LA, MacArthur PH, Xu X, Murphy E, Darley-Usmar VM, and Gladwin MT. Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration. Circ Res 100: 654-661, 2007. (Pubitemid 46594879)
46. Shiva S, Rassaf T, Patel R, and Gladwin MT. The detection of the nitrite reductase and NO-generating properties of haemoglobin by mitochondrial inhibition. Cardiovasc Res 15: 566-573, 2010.
47. Shiva S, Sack MN, Greer JJ, Duranski M, Ringwood LA, Burwell L, Wang X, MacArthur PH, Shoja A, Raghavachari N, Calvert JW, Brookes PS, Lefer DJ, and Gladwin MT. Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer. J Exp Med 204: 2089-2102, 2007. (Pubitemid 47360871)
48. Shiva S, Wang X, Ringwood LA, Xu X, Yuditskaya S, Annavajjhala V, Miyajima H, Hogg N, Harris ZL, and Gladwin MT. Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrineNOhomeostasis. NatChem Biol 2: 486-493, 2006. (Pubitemid 44266311)
49. Vanin AF, Bevers LM, Slama-Schwok A, and van Faassen EE. Nitric oxide synthase reduces nitrite to NO under anoxia. Cell Mol Life Sci 64: 96-103, 2007. (Pubitemid 46159448)
50. Webb A, Bond R, McLean P, Uppal R, Benjamin N, and Ahluwalia A. Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. Proc Natl Acad Sci USA 101: 13683-13688, 2004. (Pubitemid 39238463)
51. Yadav AK, Doran SF, Samal AA, Sharma R, Vedagiri K, Postlethwait EM, Squadrito GL, Fanucchi MV, Roberts LJ, 2nd, Patel RP, and Matalon S. Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite. Am J Physiol Lung Cell Mol Physiol 300: L362-369, 2011.