Early intravenous infusion of sodium nitrite protects brain against in vivo ischemia-reperfusion injury

Stroke

Volumn 37, Issue 11, 2006, Pages 2744-2750

  Jung, Keun Hwa ^a   Chu, Kon ^a   Ko, Song Yi ^a   Lee, Soon Tae ^a   Sinn, Dong In ^a   Park, Dong Kyu ^a   Kim, Jeong Min ^a   Song, Eun Cheol ^a   Kim, Manho ^a   Roh, Jae Kyu ^a  

^a Seoul National University Hospital   (South Korea)

Author keywords

Cerebral ischemia reperfusion injury; Neuroprotection; Nitric oxide; Nitrite; Oxidative stress

Indexed keywords

2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; 3 NITROTYROSINE; HYDROETHIDINE; NITRIC OXIDE; NITRITE; OXYGEN; SCAVENGER; SODIUM NITRATE; SODIUM NITRITE; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN BLOOD FLOW; BRAIN FUNCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; CEREBROVASCULAR ACCIDENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REDUCTION; REPERFUSION INJURY; ANIMAL; BRAIN; DRUG EFFECT; INTRAVENOUS DRUG ADMINISTRATION; PATHOLOGY; TIME;

ANIMALS; BRAIN; INFUSIONS, INTRAVENOUS; MALE; NEUROPROTECTIVE AGENTS; RATS; REPERFUSION INJURY; SODIUM NITRITE; TIME FACTORS;

EID: 33750934803     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000245116.40163.1c     Document Type: Article

References (24)

1. Gursoy-Ozdemir Y, Can A, Dalkara T. Reperfusion-induced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia. Stroke. 2004;35:1449-1453.
2. Iadecola C. Bright and dark sides of nitric oxide in ischemic brain injury. Trends Neurosci. 1997;20:132-139.
3. Stagliano NE, Dietrich WD, Prado R, Green EJ, Busto R. The role of nitric oxide in the pathophysiology of thromboembolic stroke in the rat. Brain Res. 1997;759:32-40.
4. Mohanakumar KP, Thomas B, Sharma SM, Muralikrishnan D, Chowdhury R, Chiueh CC. Nitric oxide: an antioxidant and neuroprotector. Ann N Y Acad Sci. 2002;962:389-401.
5. Beckman JS. Interactions of oxidants, nitric oxide, and antioxidant defenses in cerebral ischemia and injury. In: Ginsberg MD, Bogousslavsky J, eds. Cerebrovascular Disease. Boston, MA: Blackwell Science; 1998:455-470.
6. Amin-Hanjani S, Stagliano NE, Yamada M, Huang PL, Liao JK, Moskowitz MA. Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice. Stroke. 2001;32:980-986.
7. Buisson A, Margaill I, Callebert J, Plotkine M, Boulu RG. Mechanisms involved in the neuroprotective activity of a nitric oxide synthase inhibitor during focal cerebral ischemia. J Neurochem. 1993;61:690-696.
8. Dimmeler S, Zeiher AM. Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide. Nitric Oxide. 1997;1:275-281.
9. Zhang R, Zhang L, Zhang Z, Wang Y, Lu M, Lapointe M, Chopp M. A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats. Ann Neurol. 2001;50:602-611.
10. Zhang F, White JG, Iadecola C. Nitric oxide donors increase blood flow and reduce brain damage in focal ischemia: evidence that nitric oxide is beneficial in the early stages of cerebral ischemia. J Cereb Blood Flow Metab. 1994;14:217-226.
11. Morikawa E, Moskowitz MA, Huang Z, Yoshida T, Irikura K, Dalkara T. L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat. Stroke. 1994;25:429-435.
12. Cosby K, Partovi KS, Crawford JH, Patel RP, Reiter CD, Martyr S, Yang BK, Waclawiw MA, Zalos G, Xu X, Huang KT, Shields H, Kim-Shapiro DB, Schecter AN, Cannon RO, Gladwin MT. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the circulation. Nat Med. 2003;9:1498-1505.
13. Duranski MR, Greer JMG, Dejam A, Jaganmohan S, Hogg N, Langston W, Patel RP, Yet SF, Wang Xunde Kevil CG, Gladwin MT, Lefer DJ. Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. J Clin Invest. 2005;115:1232-1240.
14. Modin A, Bjorne H, Herulf M, Alving K, Weitzberg E, Lundberg JO. Nitrite-derived nitric oxide: a possible mediator of 'acidic-metabolic' vasodilation. Acta Physiol Scand. 2001;171:9-16.
15. Lee ST, Chu K, Jung KH, Ko SY, Kim EH, Sinn DI, Lee YS, Lo EH, Kim M, Roh JK. Granulocyte colony-stimulating factor enhances angiogenesis after focal cerebral ischemia. Brain Res. 2005;1058:120-128.
16. Jung KH, Chu K, Jeong SW, Han SY, Lee ST, Kim JY, Kim M, Roh JK. HMG-CoA reductase inhibitor, atorvastatin, promotes sensorimotor recovery, suppressing acute inflammatory reaction after experimental intracerebral hemorrhage. Stroke. 2004;35:1744-1749.
17. Bindokas VP, Jordan J, Lee CC, Miller RJ. Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J Neurosci. 1996;16:1324-1336.
18. Hunter CJ, Dejam A, Blood AB, Shields H, Kim-Shapiro DB, Machado RF, Tarekegn S, Mulla N, Hopper AO, Schechter AN, Power GG, Gladwin MT. Inhaled nebulized nitrite is a hypoxiasensitive NO-dependent selective pulmonary vasodilator. Nat Med. 2004;10:1122-1127.
19. Pluta RM, Dejam A, Grimes G, Gladwin MT, and Oldfield EH. Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. JAMA. 2005;293:1477-1484.
20. Basireddy M, Isbell TS, Teng X, Patel RP, Agarwal A. Effects of sodium nitrite on ischemia-reperfusion injury in the rat kidney. Am J Physiol Renal Physiol. 2006;290:F779-F786.
21. Akaike T, Yoshida M, Miyamoto Y, Sato K, Kohno M, Sasamoto K, Miyazaki K, Ueda S, Maeda H. Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/NO through a radical reaction. Biochemistry. 1993;32:827-832.
22. Garthwaite J, Boulton CL. Nitric oxide signaling in the central nervous system. Annu Rev Physiol. 1995;57:683-706.
23. Mannick JB, Hausladen A, Liu L, Hess DT, Zeng M, Miao QX, Kane LS, Gow AJ, Stamler JS. Fas-induced caspase denitrosylation. Science. 1999;284:651-654.
24. Schopfer F, Baker PRS, Freeman BA. NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response? Trends Biochem Sci. 2003;28:646-654.