-
1
-
-
39049161187
-
Environmental levels, toxicity and human exposure to tributyltin (TBT)-contaminated marine environment. A review
-
Antizar-Ladislao B.2008.Environmental levels, toxicity and human exposure to tributyltin (TBT)-contaminated marine environment. A review.Environ Int34:292-308.
-
(2008)
Environ Int
, vol.34
, pp. 292-308
-
-
Antizar-Ladislao, B.1
-
2
-
-
0038172423
-
Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: Possible implications for toxicogenomics use of in vitro systems
-
Boess F, Kamber M, Romer S, Gasser R, Muller D, Albertini S, Suter L.2003.Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: Possible implications for toxicogenomics use of in vitro systems.Toxicol Sci73:386-402.
-
(2003)
Toxicol Sci
, vol.73
, pp. 386-402
-
-
Boess, F.1
Kamber, M.2
Romer, S.3
Gasser, R.4
Muller, D.5
Albertini, S.6
Suter, L.7
-
3
-
-
33845367029
-
Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase
-
Boudreau RT, Conrad DM, Hoskin DW.2007.Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.Cell Signal19:139-151.
-
(2007)
Cell Signal
, vol.19
, pp. 139-151
-
-
Boudreau, R.T.1
Conrad, D.M.2
Hoskin, D.W.3
-
4
-
-
14244258402
-
Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens
-
Chen JR, Plotkin LI, Aguirre JI, Han L, Jilka RL, Kousteni S, Bellido T, Manolagas SC.2005.Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens.J Biol Chem280:4632-4638.
-
(2005)
J Biol Chem
, vol.280
, pp. 4632-4638
-
-
Chen, J.R.1
Plotkin, L.I.2
Aguirre, J.I.3
Han, L.4
Jilka, R.L.5
Kousteni, S.6
Bellido, T.7
Manolagas, S.C.8
-
5
-
-
51349166119
-
Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5
-
Chen L, Liu L, Huang S.2008.Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5.Free Radic Biol Med45:1035-1044.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1035-1044
-
-
Chen, L.1
Liu, L.2
Huang, S.3
-
6
-
-
84856062120
-
2011. Protoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase π
-
Chen WY, Hsieh YA, Tsai CI, Kang YF, Chang FR, Wu YC, Wu CC.2011. Protoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase π.Invest New Drugs29:1347-1359.
-
Invest New Drugs
, vol.29
, pp. 1347-1359
-
-
Chen, W.Y.1
Hsieh, Y.A.2
Tsai, C.I.3
Kang, Y.F.4
Chang, F.R.5
Wu, Y.C.6
Wu, C.C.7
-
7
-
-
77951652653
-
Involvement of p38 MAPK- and JNK-modulated expression of Bcl-2 and Bax in Naja nigricollis CMS-9-induced apoptosis of human leukemia K562 cells
-
Chen YJ, Liu WH, Kao PH, Wang JJ, Chang LS.2010b.Involvement of p38 MAPK- and JNK-modulated expression of Bcl-2 and Bax in Naja nigricollis CMS-9-induced apoptosis of human leukemia K562 cells.Toxicon55:1306-1316.
-
(2010)
Toxicon
, vol.55
, pp. 1306-1316
-
-
Chen, Y.J.1
Liu, W.H.2
Kao, P.H.3
Wang, J.J.4
Chang, L.S.5
-
8
-
-
77957704267
-
Activation of p44/42 MAPK plays a role in the TBT-induced loss of human natural killer (NK) cell function
-
Dudimah FD, Griffey D, Wang X, Whalen MM.2010.Activation of p44/42 MAPK plays a role in the TBT-induced loss of human natural killer (NK) cell function.Cell Biol Toxicol26:435-444.
-
(2010)
Cell Biol Toxicol
, vol.26
, pp. 435-444
-
-
Dudimah, F.D.1
Griffey, D.2
Wang, X.3
Whalen, M.M.4
-
9
-
-
34250827786
-
Tributyltin induces apoptotic signaling in hepatocytes through pathways involving the endoplasmic reticulum and mitochondria
-
Grondin M, Marion M, Denizeau F, Averill-Bates DA.2007.Tributyltin induces apoptotic signaling in hepatocytes through pathways involving the endoplasmic reticulum and mitochondria.Toxicol Appl Pharmacol222:57-68.
-
(2007)
Toxicol Appl Pharmacol
, vol.222
, pp. 57-68
-
-
Grondin, M.1
Marion, M.2
Denizeau, F.3
Averill-Bates, D.A.4
-
10
-
-
79957868274
-
C-Phycocyanin: An effective protective agent against thymic atrophy by tributyltin
-
Gupta M, Dwivedi UN, Khandelwal S.2011.C-Phycocyanin: An effective protective agent against thymic atrophy by tributyltin.Toxicol Lett204:2-11.
-
(2011)
Toxicol Lett
, vol.204
, pp. 2-11
-
-
Gupta, M.1
Dwivedi, U.N.2
Khandelwal, S.3
-
11
-
-
0141755390
-
Are cultured liver cells the right tool to investigate mechanisms of liver disease or hepatotoxicity
-
Jaeschke H.2003.Are cultured liver cells the right tool to investigate mechanisms of liver disease or hepatotoxicity.Hepatology38:1053-1055.
-
(2003)
Hepatology
, vol.38
, pp. 1053-1055
-
-
Jaeschke, H.1
-
12
-
-
34047179391
-
Sphingosylphosphorylcholine induces apoptosis of endothelial cells through reactive oxygen species-mediated activation of ERK
-
Jeon ES, Lee MJ, Sung SM, Kim JH.2007.Sphingosylphosphorylcholine induces apoptosis of endothelial cells through reactive oxygen species-mediated activation of ERK.J Cell Biochem100:1536-1547.
-
(2007)
J Cell Biochem
, vol.100
, pp. 1536-1547
-
-
Jeon, E.S.1
Lee, M.J.2
Sung, S.M.3
Kim, J.H.4
-
13
-
-
41549160315
-
Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
-
Junttila MR, Li SP, Westermarck J.2008.Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival.FASEB J22:954-965.
-
(2008)
FASEB J
, vol.22
, pp. 954-965
-
-
Junttila, M.R.1
Li, S.P.2
Westermarck, J.3
-
14
-
-
77952095681
-
Organotin compounds, including Butyltins and Octyltins, in house dust from Albany, New York, USA
-
Kannan K, Takahashi S, Fujiwara N, Mizukawa H, Tanabe S.2010.Organotin compounds, including Butyltins and Octyltins, in house dust from Albany, New York, USA.Arch Environ Contam Toxicol58:901-907.
-
(2010)
Arch Environ Contam Toxicol
, vol.58
, pp. 901-907
-
-
Kannan, K.1
Takahashi, S.2
Fujiwara, N.3
Mizukawa, H.4
Tanabe, S.5
-
15
-
-
47949120075
-
Sustained ERK activation is involved in the kaempferol-induced apoptosis of breast cancer cells and is more evident under 3-D culture condition
-
Kim BW, Lee ER, Min HM, Jeong HS, Ahn JY, Kim JH, Choi HY, Choi H, Kim EY, Park SP, Cho SG.2008.Sustained ERK activation is involved in the kaempferol-induced apoptosis of breast cancer cells and is more evident under 3-D culture condition.Cancer Biol Ther7:1080-1089.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1080-1089
-
-
Kim, B.W.1
Lee, E.R.2
Min, H.M.3
Jeong, H.S.4
Ahn, J.Y.5
Kim, J.H.6
Choi, H.Y.7
Choi, H.8
Kim, E.Y.9
Park, S.P.10
Cho, S.G.11
-
16
-
-
79955759980
-
2011. Organometallic Iron (III)-Salophene exerts cytotoxic properties in neuroblastoma cells via MAPK activation and ROS generation
-
e19049
-
Kim KK, Singh RK, Strongin RM, Moore RG, Brard L, Lange TS.2011. Organometallic Iron (III)-Salophene exerts cytotoxic properties in neuroblastoma cells via MAPK activation and ROS generation.PLoS One6:e19049.
-
PLoS One
, vol.6
-
-
Kim, K.K.1
Singh, R.K.2
Strongin, R.M.3
Moore, R.G.4
Brard, L.5
Lange, T.S.6
-
17
-
-
34447545755
-
Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3
-
Komatsu M, Furukawa T, Ikeda R, Takumi S, Nong Q, Aoyama K, Akiyama S, Keppler D, Takeuchi T.2007.Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3.Toxicol Sci97:407-416.
-
(2007)
Toxicol Sci
, vol.97
, pp. 407-416
-
-
Komatsu, M.1
Furukawa, T.2
Ikeda, R.3
Takumi, S.4
Nong, Q.5
Aoyama, K.6
Akiyama, S.7
Keppler, D.8
Takeuchi, T.9
-
18
-
-
0037861856
-
Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscle
-
Lawler JM, Song W, Demaree SR.2003.Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscle.Free Radic Biol Med35:9-16.
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 9-16
-
-
Lawler, J.M.1
Song, W.2
Demaree, S.R.3
-
19
-
-
0037362372
-
Role of PP2A in the regulation of p38 MAPK activation in bovine aortic endothelial cells exposed to cyclic strain
-
Lee T, Kim SJ, Sumpio BE.2003.Role of PP2A in the regulation of p38 MAPK activation in bovine aortic endothelial cells exposed to cyclic strain.J Cell Physiol194:349-355.
-
(2003)
J Cell Physiol
, vol.194
, pp. 349-355
-
-
Lee, T.1
Kim, S.J.2
Sumpio, B.E.3
-
20
-
-
77953204596
-
Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis
-
Li W, Xie L, Chen Z, Zhu Y, Sun Y, Miao Y, Xu Z, Han X.2010.Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis.Cancer Sci101:1226-1233.
-
(2010)
Cancer Sci
, vol.101
, pp. 1226-1233
-
-
Li, W.1
Xie, L.2
Chen, Z.3
Zhu, Y.4
Sun, Y.5
Miao, Y.6
Xu, Z.7
Han, X.8
-
21
-
-
33645903229
-
Tributyltin induces DNA damage as well as oxidative damage in rats
-
Liu HG, Wang Y, Lian L, Xu LH.2006.Tributyltin induces DNA damage as well as oxidative damage in rats.Environ Toxicol21:166-171.
-
(2006)
Environ Toxicol
, vol.21
, pp. 166-171
-
-
Liu, H.G.1
Wang, Y.2
Lian, L.3
Xu, L.H.4
-
22
-
-
29544441180
-
Glutamate excitotoxicity is involved in cell death caused by tributyltin in cultured rat cortical neurons
-
Nakatsu Y, Kotake Y, Komasaka K, Hakozaki H, Taguchi R, Kume T, Akaike A, Ohta S.2006.Glutamate excitotoxicity is involved in cell death caused by tributyltin in cultured rat cortical neurons.Toxicol Sci89:235-242.
-
(2006)
Toxicol Sci
, vol.89
, pp. 235-242
-
-
Nakatsu, Y.1
Kotake, Y.2
Komasaka, K.3
Hakozaki, H.4
Taguchi, R.5
Kume, T.6
Akaike, A.7
Ohta, S.8
-
23
-
-
34447578871
-
Concentration dependence of the mechanisms of tributyltin-induced Apoptosis
-
Nakatsu Y, Kotake Y, Ohta S.2007.Concentration dependence of the mechanisms of tributyltin-induced Apoptosis.Toxicol Sci97:438-447.
-
(2007)
Toxicol Sci
, vol.97
, pp. 438-447
-
-
Nakatsu, Y.1
Kotake, Y.2
Ohta, S.3
-
24
-
-
0036220394
-
Butyltin compounds in human liver
-
Nielsen JB, Strand J.2002.Butyltin compounds in human liver.Environ Res88:129-133.
-
(2002)
Environ Res
, vol.88
, pp. 129-133
-
-
Nielsen, J.B.1
Strand, J.2
-
25
-
-
33750740797
-
In vitro metabolism of tributyltin and triphenyltin by human cytochrome P-450 isoforms
-
Ohhira S, Enomoto M, Matsui H.2006.In vitro metabolism of tributyltin and triphenyltin by human cytochrome P-450 isoforms.Toxicology228:171-177.
-
(2006)
Toxicology
, vol.228
, pp. 171-177
-
-
Ohhira, S.1
Enomoto, M.2
Matsui, H.3
-
26
-
-
0037259410
-
Metabolism of tributyltin and triphenyltin by rat, hamster and human hepatic microsomes
-
Ohhira S, Watanabe M, Matsui H.2003.Metabolism of tributyltin and triphenyltin by rat, hamster and human hepatic microsomes.Arch Toxicol77:138-144.
-
(2003)
Arch Toxicol
, vol.77
, pp. 138-144
-
-
Ohhira, S.1
Watanabe, M.2
Matsui, H.3
-
27
-
-
0032892149
-
An elevated bax/bcl-2 ratio corresponds with the onset of prostate epithelial cell apoptosis
-
Perlman H, Zhang X, Chen MW, Walsh K, Buttyan R.1999.An elevated bax/bcl-2 ratio corresponds with the onset of prostate epithelial cell apoptosis.Cell Death Differ6:48-54.
-
(1999)
Cell Death Differ
, vol.6
, pp. 48-54
-
-
Perlman, H.1
Zhang, X.2
Chen, M.W.3
Walsh, K.4
Buttyan, R.5
-
28
-
-
0035863784
-
The serine/threonine phosphatase, PP2A: Endogenous regulator of inflammatory cell signaling
-
Shanley TP, Vasi N, Denenberg A, Wong HR.2001.The serine/threonine phosphatase, PP2A: Endogenous regulator of inflammatory cell signaling.J Immunol166:966-972.
-
(2001)
J Immunol
, vol.166
, pp. 966-972
-
-
Shanley, T.P.1
Vasi, N.2
Denenberg, A.3
Wong, H.R.4
-
29
-
-
70249138391
-
Novel indoloquinoline derivative, IQDMA, induces G(2)/M phase arrest and apoptosis in A549 cells through JNK/p38 MAPK signaling activation
-
Su JC, Lin KL, Chien CM, Lu CM, Chen YL, Chang LS, Lin SR.2009.Novel indoloquinoline derivative, IQDMA, induces G(2)/M phase arrest and apoptosis in A549 cells through JNK/p38 MAPK signaling activation.Life Sci85:505-516.
-
(2009)
Life Sci
, vol.85
, pp. 505-516
-
-
Su, J.C.1
Lin, K.L.2
Chien, C.M.3
Lu, C.M.4
Chen, Y.L.5
Chang, L.S.6
Lin, S.R.7
-
30
-
-
0037174152
-
p38 mitogen-activated protein kinase dephosphorylation is regulated by protein phosphatase 2A in human platelets activated by collagen
-
Sundaresan P, Farndale RW.2002.p38 mitogen-activated protein kinase dephosphorylation is regulated by protein phosphatase 2A in human platelets activated by collagen.FEBS Lett528:139-144.
-
(2002)
FEBS Lett
, vol.528
, pp. 139-144
-
-
Sundaresan, P.1
Farndale, R.W.2
-
31
-
-
37349000346
-
Critical role of hydrogen peroxide in the differential susceptibility of Th1 and Th2 cells to tributyltin-induced apoptosis
-
Tada-Oikawa S, Kato T, Kuribayashi K, Nishino K, Murata M, Kawanishi S.2008.Critical role of hydrogen peroxide in the differential susceptibility of Th1 and Th2 cells to tributyltin-induced apoptosis.Biochem Pharmacol75:552-561.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 552-561
-
-
Tada-Oikawa, S.1
Kato, T.2
Kuribayashi, K.3
Nishino, K.4
Murata, M.5
Kawanishi, S.6
-
32
-
-
79952371679
-
Icaritin causes sustained ERK1/2 activation and induces apoptosis in human endometrial cancer cells
-
e16781
-
Tong JS, Zhang QH, Huang X, Fu XQ, Qi ST., Wang YP, Hou Y, Sheng J, Sun QY. 2011.Icaritin causes sustained ERK1/2 activation and induces apoptosis in human endometrial cancer cells.PLoS One6:e16781.
-
(2011)
PLoS One
, vol.6
-
-
Tong, J.S.1
Zhang, Q.H.2
Huang, X.3
Fu, X.Q.4
Qi, S.T.5
Wang, Y.P.6
Hou, Y.7
Sheng, J.8
Sun, Q.Y.9
-
33
-
-
0028072876
-
Comparison of hepatotoxicity caused by mono-, di- and tributyltin compounds in mice
-
Ueno S, Susa N, Furukawa Y, Sugiyama M.1994.Comparison of hepatotoxicity caused by mono-, di- and tributyltin compounds in mice.Arch Toxicol69:30-34.
-
(1994)
Arch Toxicol
, vol.69
, pp. 30-34
-
-
Ueno, S.1
Susa, N.2
Furukawa, Y.3
Sugiyama, M.4
-
34
-
-
63449141977
-
JNK and p38 MAPK are independently involved in tributyltin-mediated cell death in rainbow trout (Oncorhynchus mykiss) RTG-2 cells
-
Urushibara N, Mitsuhashic S, Sasaki T, Kasaia H, Yoshimizu M, Fujita H, Oda A.2009.JNK and p38 MAPK are independently involved in tributyltin-mediated cell death in rainbow trout (Oncorhynchus mykiss) RTG-2 cells.Comp Biochem Physiol C Toxicol Pharmacol149:468-475.
-
(2009)
Comp Biochem Physiol C Toxicol Pharmacol
, vol.149
, pp. 468-475
-
-
Urushibara, N.1
Mitsuhashic, S.2
Sasaki, T.3
Kasaia, H.4
Yoshimizu, M.5
Fujita, H.6
Oda, A.7
-
35
-
-
0028206341
-
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
-
Yin XM, Oltvai ZN, Korsmeyer SJ.1994.BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.Nature369:321-323.
-
(1994)
Nature
, vol.369
, pp. 321-323
-
-
Yin, X.M.1
Oltvai, Z.N.2
Korsmeyer, S.J.3
-
36
-
-
79955805229
-
Disulfiram modulated ROS-MAPK and NFkB pathways and targeted breast cancer cells with cancer stem cell-like properties
-
Yip NC, Fombon IS, Liu P, Brown S, Kannappan V, Armesilla AL, Xu B, Cassidy J, Darling JL, Wang W.2011.Disulfiram modulated ROS-MAPK and NFkB pathways and targeted breast cancer cells with cancer stem cell-like properties.Br J Cancer104:1564-1574.
-
(2011)
Br J Cancer
, vol.104
, pp. 1564-1574
-
-
Yip, N.C.1
Fombon, I.S.2
Liu, P.3
Brown, S.4
Kannappan, V.5
Armesilla, A.L.6
Xu, B.7
Cassidy, J.8
Darling, J.L.9
Wang, W.10
-
37
-
-
31344437880
-
Okadaic acid induces JNK activation, bim overexpression and mitochondrial dysfunction in cultured rat cortical neurons
-
Yoon S, Choi J, Yoon J, Huh JW, Kim D.2006.Okadaic acid induces JNK activation, bim overexpression and mitochondrial dysfunction in cultured rat cortical neurons.Neurosci Lett394:190-195.
-
(2006)
Neurosci Lett
, vol.394
, pp. 190-195
-
-
Yoon, S.1
Choi, J.2
Yoon, J.3
Huh, J.W.4
Kim, D.5
-
38
-
-
50049130174
-
Tributyltin exposure causes brain damage in Sebastiscus marmoratus
-
Zhang J, Zuo Z, Chen R, Chen Y, Wang C, 2008.Tributyltin exposure causes brain damage in Sebastiscus marmoratus.Chemosphere73:337-343.
-
(2008)
Chemosphere
, vol.73
, pp. 337-343
-
-
Zhang, J.1
Zuo, Z.2
Chen, R.3
Chen, Y.4
Wang, C.5
-
39
-
-
84879601126
-
2011. Inhibition of PP2A and the consequent activation of JNK/c-Jun are involved in tributyltin-induced apoptosis in human amnionic cells
-
in press, doi: 10.1002/tox.20730
-
Zhang Y, Liang J, Sun L, Guo Z, Xu L.2011. Inhibition of PP2A and the consequent activation of JNK/c-Jun are involved in tributyltin-induced apoptosis in human amnionic cells.Environ Toxicol (in press); doi: 10.1002/tox.20730.
-
Environ Toxicol
-
-
Zhang, Y.1
Liang, J.2
Sun, L.3
Guo, Z.4
Xu, L.5
-
40
-
-
79751483217
-
Tributyltin causes obesity and hepatic steatosis in male mice
-
Zuo Z, Chen S, Wu T, Zhang J, Su Y, Chen Y, Wang C.2011.Tributyltin causes obesity and hepatic steatosis in male mice.Environ Toxicol26:79-85.
-
(2011)
Environ Toxicol
, vol.26
, pp. 79-85
-
-
Zuo, Z.1
Chen, S.2
Wu, T.3
Zhang, J.4
Su, Y.5
Chen, Y.6
Wang, C.7
|