Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti- versus pro-apoptotic effects of estrogens

Journal of Biological Chemistry

Volumn 280, Issue 6, 2005, Pages 4632-4638

  Chen, Jin Ran ^a   Plotkin, Lilian I ^a   Aguirre, José Ignacio ^a   Han, Li ^a   Jilka, Robert L ^a   Kousteni, Stavroula ^a   Bellido, Teresita ^a   Manolagas, Stavros C ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BONE; DRUG PRODUCTS; FLUORESCENCE; MUTAGENS; PHOSPHORS; REACTION KINETICS; SIGNAL PROCESSING; TOXICITY;

EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK); OSTEOCLASTS; PRO-APOPTOTIOC EFFECTS; STEROIDS;

HORMONES;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ADENYLATE CYCLASE; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ESTRADIOL; GREEN FLUORESCENT PROTEIN; LEPTOMYCIN B; MITOGEN ACTIVATED PROTEIN KINASE; SEX HORMONE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; NONHUMAN; OSTEOCLAST; OSTEOCYTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL NUCLEUS; CELLS, CULTURED; CHOLERA TOXIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOPLASM; ENZYME ACTIVATION; ESTRADIOL; ESTROGENS; ETOPOSIDE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FATTY ACIDS, UNSATURATED; GREEN FLUORESCENT PROTEINS; KINETICS; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MUTATION; OSTEOCLASTS; PHOSPHORYLATION; PLASMIDS; TIME FACTORS; TRANSFECTION;

EID: 14244258402     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M411530200     Document Type: Article

References (54)

1. Manolagas, S. C. (2000) Endocr. Rev. 21, 115-137
2. Manolagas, S. C., Kousteni, S., and Jilka, R. L. (2002) Recent Prog. Horm. Res. 57, 385-409
3. Manolagas, S. C., Kousteni, S., Chen, J.-R., Schuller, M., Plotkin, L. I., and Bellido, T. (2004) Kidney Int. Suppl. 91, S41-S49
4. Kousteni, S., Chen, J.-R., Bellido, T., Han, L., Ali, A. A., O'Brien, C., Plotkin, L. I., Fu, Q., Mancino, A. T., Wen, Y., Vertino, A. M., Powers, C. C., Stewart, S. A., Ebert, R., Parfitt, A. M., Weinstein, R. S., Jilka, R. L., and Manolagas, S. C. (2002) Science 298, 843-846
5. Aarden, E. M., Burger, E. H., and Nijweide, P. J. (1994) J. Cell. Biochem. 55, 287-299
6. Jilka, R. L., Weinstein, R. S., Takahashi, K., Parfitt, A. M., and Manolagas, S. C. (1996) J. Clin. Investig. 97, 1732-1740
7. Weinstein, R. S., Jilka, R. L., Parfitt, A. M., and Manolagas, S. C. (1998) J. Clin. Investig. 102, 274-282
8. Jilka, R. L., Hangoc, G., Girasole, G., Passeri, G., Williams, D. C., Abrams, J. S., Boyce, B., Broxmeyer, H., and Manolagas, S. C. (1992) Science 257, 88-91
9. Weinstein, R. S., Chen, J. R., Powers, C. C., Stewart, S. A., Landes, R. D., Bellido, T., Jilka, R. L., Parfitt, A. M., and Manolagas, S. C. (2002) J. Clin. Investig. 109, 1041-1048
10. Plotkin, L. I., Weinstein, R. S., Parfitt, A. M., Roberson, P. K., Manolagas, S. C., and Bellido, T. (1999) J. Clin. Investig. 104, 1363-1374
11. Jilka, R. L., Weinstein, R. S., Bellido, T., Roberson, P., Parfitt, A. M., and Manolagas, S. C. (1999) J. Clin. Investig. 104, 439-446
12. Bellido, T., Ali, A. A., Plotkin, L. L., Fu, Q., Gubrij, I., Roberson, P. K., Weinstein, R. S., O'Brien, C. A., Manolagas, S. C., and Jilka, R. L. (2003) J. Biol. Chem. 278, 50259-50272
13. Kousteni, S., Han, L., Chen, J.-R., Almeida, M., Plotkin, L. I., Bellido, T., and Manolagas, S. C. (2003) J. Clin. Investig. 111, 1651-1664
14. Kousteni, S., Bellido, T., Plotkin, L. I., O'Brien, C. A., Bodenner, D. L., Han, K., DiGregorio, G., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Roberson, P. K., Weinstein, R. S., Jilka, R. L., and Manolagas, S. C. (2001) Cell 104, 719-730
15. Shevde, N. K., and Pike, J. W. (1996) Blood 87, 2683-2692
16. Hughes, D. E., Dai, A., Tiffee, J. C., Li, H. H., Mundy, G. R., and Boyce, B. F. (1996) Nat. Med. 2, 1132-1136
17. Kameda, T., Mano, H., Yuasa, T., Mori, Y., Miyazawa, K., Shiokawa, M., Nakamaru, Y., Hiroi, E., Hiura, K., Kameda, A., Yang, N. N., Hakeda, Y., and Kumegawa, M. (1997) J. Exp. Med. 186, 489-495
18. Marshall, C. J. (1995) Cell 80, 179-185
19. Stanciu, M., and DeFranco, D. B. (2002) J. Biol. Chem. 277, 4010-4017
20. Tang, D., Wu, D., Hirao, A., Lahti, J. M., Liu, L., Mazza, B., Kidd, V. J., Mak, T. W., and Ingram, A. J. (2002) J. Biol. Chem. 277, 12710-12717
21. Recchia, I., Rucci, N., Funari, A., Migliaccio, S., Taranta, A., Longo, M., Kneissel, M., Susa, M., Fabbro, D., and Teti, A. (2004) Bone (N. Y.) 34, 65-79
22. Assoian, R. K. (2002) Nat. Cell Biol. 4, E187-E188
23. Murphy, L. O., Smith, S., Chen, R. H., Fingar, D. C., and Blenis, J. (2002) Nat. Cell Biol. 4, 556-564
24. Heinrich, R., Neel, B. G., and Rapoport, T. A. (2002) Mol. Cell 9, 957-970
25. Roovers, K., Davey, G., Zhu, X., Bottazzi, M. E., and Assoian, R. K. (1999) Mol. Biol. Cell 10, 3197-3204
26. Balmanno, K., and Cook, S. J. (1999) Oncogene 18, 3085-3097
27. Weber, J. D., Raben, D. M., Phillips, P. J., and Baldassare, J. J. (1997) Biochem. J. 326, 61-68
28. New, L., Li, Y., Ge, B., Zhong, H., Mansbridge, J., Liu, K., and Han, J. (2001) J. Cell. Biochem. 83, 585-596
29. Lenormand, P., Brondello, J. M., Brunet, A., and Pouyssegur, J. (1998) J. Cell Biol. 142, 625-633
30. Khokhlatchev, A. V., Canagarajah, B., Wilsbacher, J., Robinson, M., Atkinson, M., Goldsmith, E., and Cobb, M. H. (1998) Cell 93, 605-615
31. Rubinfeld, H., Hanoch, T., and Seger, R. (1999) J. Biol. Chem. 274, 30349-30352
32. Mansour, S. J., Matten, W. T., Hermann, A. S., Candia, J. M., Rong, S., Fukasawa, K., Vande, W. G., and Ahn, N. G. (1994) Science 265, 966-970
33. Kalderon, D., Roberts, B. L., Richardson, W. D., and Smith, A. E. (1984) Cell 39, 499-509
34. Filardo, E. J., Quinn, J. A., Frackelton, A. R., Jr., and Bland, K. I. (2002) Mol. Endocrinol. 16, 70-84
35. Boyce, B. F., Xing, L., Jilha, R. L., Bellido, T., Weinstein, R. S., Parfit, A. M., and Manolagas, S. C (2002) in Principles of Bone Biology (Bilezikian, J. P., Raisz, L. G., and Rodan, G. A., eds) pp. 151-168, Academic Press, Orlando, FL
36. Gingery, A., Bradley, E., Shaw, A., and Oursler, M. J. (2003) J. Cell. Biochem. 89, 165-179
37. Lee, Z. H., Lee, S. E., Kim, C. W., Lee, S. H., Kim, S. W., Kwack, K., Walsh, K., and Kim, H. H. (2002) J. Biochem. (Tokyo) 131, 161-166
38. Lee, S. E., Chung, W. J., Kwak, H. B., Chung, C. H., Kwack, K. B., Lee, Z. H., and Kim, H. H. (2001) J. Biol. Chem. 276, 49343-49349
39. Nakamura, H., Hirata, A., Tsuji, T., and Yamamoto, T. (2003) J. Bone Miner. Res. 18, 1198-1205
40. Selander, K. S., Harkonen, P. L., Valve, E., Monkkonen, J., Hannuniemi, R., and Vaananen, H. K. (1996) Mol. Cell. Endocrinol. 122, 119-129
41. Kanaoka, K., Kobayashi, Y., Hashimoto, F., Nakashima, T., Shibata, M., Kobayashi, K., Kato, Y., and Sakai, H. (2000) Endocrinology 141, 2995-3005
42. Poli, V., Balena, R., Fattori, E., Markatos, A., Yamamoto, A., Tanaka, H., Ciliberto, G., Rodan, G. A., and Costantini, F. (1994) EMBO J. 13, 1189-1196
43. Bellido, T., Jilka, R. L., Boyce, B. F., Girasole, G., Broxmeyer, H., Dalrymple, S. A., Murray, R., and Manolagas, S. C. (1995) J. Clin. Investig. 95, 2886-2895
44. Stein, B., and Yang, M. X. (1995) Mol. Cell. Biol. 15, 4971-4979
45. Pottratz, S. T., Bellido, T., Mocharla, H., Crabb, D., and Manolagas, S. C. (1994) J. Clin. Investig. 93, 944-950
46. Srivastava, S., Neale, W. M., Kimble, R. B., Rizzo, M., Zahner, M., Milbrandt, J., Patrick, R. F., and Paciuci, R. (1998) J. Clin. Investig. 102, 1850-1859
47. Srivastava, S., Weitzmann, M. N., Cenci, S., Ross, F. P., Adler, S., and Pacifici, R. (1999) J. Clin. Investis. 104, 503-513
48. Cenci, S., Weitzmann, M. N., Roggia, C., Namba, N., Novack, D., Woodring, J., and Pacifici, R. (2000) J. Clin. Investig. 106, 1229-1237
49. Oursler, M. J., Pederson, L., Fitzpatrick, L., Riggs, B. L., and Spelsberg, T. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5227-5231
50. Pascoe, D., and Oursler, M. J. (2001) J. Bone Miner. Res. 16, 1028-1036
51. David, J. P., Sabapathy, K., Hoffmann, O., Idarraga, M. H., and Wagner, E. F. (2002) J. Cell Sci. 115, 4317-4325
52. Shevde, N. K., Bendixen, A. C., Dienger, K. M., and Pike, J. W. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7829-7834
53. Lean, J. M., Davies, J. T., Fuller, K., Jagger, C. J., Kirstein, B., Partington, G. A., Urry, Z. L., and Chambers, T. J. (2003) J. Clin. Investig. 112, 915-923
54. Chen, J. R., Han, L., Zimniak, P., O'Brien, C. A., Bellido, T., Kousteni, S., and Manolagas, S. C. (2004) J. Bone Miner. Res. 19, Suppl. 1, S284 (abstr.)