-
2
-
-
80052457992
-
Interactions of diarrhea, pneumonia, and malnutrition in childhood: Recent evidence from developing countries
-
Schlaudecker, E. P., M. C. Steinhoff, and S. R. Moore. 2011. Interactions of diarrhea, pneumonia, and malnutrition in childhood: recent evidence from developing countries. Curr. Opin. Infect. Dis. 24: 496-502.
-
(2011)
Curr. Opin. Infect. Dis.
, vol.24
, pp. 496-502
-
-
Schlaudecker, E.P.1
Steinhoff, M.C.2
Moore, S.R.3
-
4
-
-
84255199079
-
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
-
Wang, R., C. P. Dillon, L. Z. Shi, S. Milasta, R. Carter, D. Finkelstein, L. L. McCormick, P. Fitzgerald, H. Chi, J. Munger, and D. R. Green. 2011. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 35: 871-882.
-
(2011)
Immunity
, vol.35
, pp. 871-882
-
-
Wang, R.1
Dillon, C.P.2
Shi, L.Z.3
Milasta, S.4
Carter, R.5
Finkelstein, D.6
McCormick, L.L.7
Fitzgerald, P.8
Chi, H.9
Munger, J.10
Green, D.R.11
-
5
-
-
44449165597
-
Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways
-
Jacobs, S. R., C. E. Herman, N. J. Maciver, J. A. Wofford, H. L. Wieman, J. J. Hammen, and J. C. Rathmell. 2008. Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. J. Immunol. 180: 4476-4486.
-
(2008)
J. Immunol.
, vol.180
, pp. 4476-4486
-
-
Jacobs, S.R.1
Herman, C.E.2
Maciver, N.J.3
Wofford, J.A.4
Wieman, H.L.5
Hammen, J.J.6
Rathmell, J.C.7
-
6
-
-
79953172571
-
Cutting edge: Distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
-
Michalek, R. D., V. A. Gerriets, S. R. Jacobs, A. N. Macintyre, N. J. MacIver, E. F. Mason, S. A. Sullivan, A. G. Nichols, and J. C. Rathmell. 2011. Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. J. Immunol. 186: 3299-3303.
-
(2011)
J. Immunol.
, vol.186
, pp. 3299-3303
-
-
Michalek, R.D.1
Gerriets, V.A.2
Jacobs, S.R.3
Macintyre, A.N.4
Maciver, N.J.5
Mason, E.F.6
Sullivan, S.A.7
Nichols, A.G.8
Rathmell, J.C.9
-
7
-
-
79960369458
-
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
Shi, L. Z., R. Wang, G. Huang, P. Vogel, G. Neale, D. R. Green, and H. Chi. 2011. HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. J. Exp. Med. 208: 1367-1376.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1367-1376
-
-
Shi, L.Z.1
Wang, R.2
Huang, G.3
Vogel, P.4
Neale, G.5
Green, D.R.6
Chi, H.7
-
8
-
-
55249114228
-
Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
-
Cham, C. M., G. Driessens, J. P. O'Keefe, and T. F. Gajewski. 2008. Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells. Eur. J. Immunol. 38: 2438-2450.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 2438-2450
-
-
Cham, C.M.1
Driessens, G.2
O'Keefe, J.P.3
Gajewski, T.F.4
-
9
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague, C. T., I. S. Farooqi, J. P. Whitehead, M. A. Soos, H. Rau, N. J. Wareham, C. P. Sewter, J. E. Digby, S. N. Mohammed, J. A. Hurst, et al. 1997. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387: 903-908.
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
Sewter, C.P.7
Digby, J.E.8
Mohammed, S.N.9
Hurst, J.A.10
-
10
-
-
80053258367
-
Leptin in human physiology and pathophysiology
-
Mantzoros, C. S., F. Magkos, M. Brinkoetter, E. Sienkiewicz, T. A. Dardeno, S. Y. Kim, O. P. Hamnvik, and A. Koniaris. 2011. Leptin in human physiology and pathophysiology. Am. J. Physiol. Endocrinol. Metab. 301: E567-E584.
-
(2011)
Am. J. Physiol. Endocrinol. Metab.
, vol.301
-
-
Mantzoros, C.S.1
Magkos, F.2
Brinkoetter, M.3
Sienkiewicz, E.4
Dardeno, T.A.5
Kim, S.Y.6
Hamnvik, O.P.7
Koniaris, A.8
-
12
-
-
77951686557
-
Role of leptin in the activation of immune cells
-
Fernández-Riejos, P., S. Najib, J. Santos-Alvarez, C. Martín-Romero, A. Pérez-Pérez, C. González-Yanes, and V. Sánchez-Margalet. 2010. Role of leptin in the activation of immune cells. Mediators Inflamm. 2010: 568343.
-
(2010)
Mediators Inflamm.
, vol.2010
, pp. 568343
-
-
Fernández-Riejos, P.1
Najib, S.2
Santos-Alvarez, J.3
Martín-Romero, C.4
Pérez-Pérez, A.5
González-Yanes, C.6
Sánchez-Margalet, V.7
-
13
-
-
0033304576
-
Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
-
Ozata, M., I. C. Ozdemir, and J. Licinio. 1999. Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. J. Clin. Endocrinol. Metab. 84: 3686-3695.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 3686-3695
-
-
Ozata, M.1
Ozdemir, I.C.2
Licinio, J.3
-
14
-
-
0018148843
-
Impairment of cell-mediated immunity in mutation diabetic mice (db/db)
-
Mandel, M. A., and A. A. Mahmoud. 1978. Impairment of cell-mediated immunity in mutation diabetic mice (db/db). J. Immunol. 120: 1375-1377.
-
(1978)
J. Immunol.
, vol.120
, pp. 1375-1377
-
-
Mandel, M.A.1
Mahmoud, A.A.2
-
15
-
-
33846409122
-
Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor
-
Farooqi, I. S., T. Wangensteen, S. Collins, W. Kimber, G. Matarese, J. M. Keogh, E. Lank, B. Bottomley, J. Lopez-Fernandez, I. Ferraz-Amaro, et al. 2007. Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor. N. Engl. J. Med. 356: 237-247.
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 237-247
-
-
Farooqi, I.S.1
Wangensteen, T.2
Collins, S.3
Kimber, W.4
Matarese, G.5
Keogh, J.M.6
Lank, E.7
Bottomley, B.8
Lopez-Fernandez, J.9
Ferraz-Amaro, I.10
-
16
-
-
0018861450
-
Cell-mediated immunity in genetically obese C57BL/6J ob/ob) mice
-
Chandra, R. K. 1980. Cell-mediated immunity in genetically obese C57BL/6J ob/ob) mice. Am. J. Clin. Nutr. 33: 13-16.
-
(1980)
Am. J. Clin. Nutr.
, vol.33
, pp. 13-16
-
-
Chandra, R.K.1
-
17
-
-
75749150169
-
Cellular immunity before and after leptin replacement therapy
-
Paz-Filho, G. J., T. Delibasi, H. K. Erol, M. L. Wong, and J. Licinio. 2009. Cellular immunity before and after leptin replacement therapy. J. Pediatr. Endocrinol. Metab. 22: 1069-1074.
-
(2009)
J. Pediatr. Endocrinol. Metab.
, vol.22
, pp. 1069-1074
-
-
Paz-Filho, G.J.1
Delibasi, T.2
Erol, H.K.3
Wong, M.L.4
Licinio, J.5
-
18
-
-
79951993450
-
Congenital leptin deficiency: Diagnosis and effects of leptin replacement therapy
-
Paz-Filho, G., C. Mastronardi, T. Delibasi, M. L. Wong, and J. Licinio. 2010. Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy. Arq. Bras. Endocrinol. Metabol. 54: 690-697.
-
(2010)
Arq. Bras. Endocrinol. Metabol.
, vol.54
, pp. 690-697
-
-
Paz-Filho, G.1
Mastronardi, C.2
Delibasi, T.3
Wong, M.L.4
Licinio, J.5
-
19
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
Farooqi, I. S., G. Matarese, G. M. Lord, J. M. Keogh, E. Lawrence, C. Agwu, V. Sanna, S. A. Jebb, F. Perna, S. Fontana, et al. 2002. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J. Clin. Invest. 110: 1093-1103.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
Keogh, J.M.4
Lawrence, E.5
Agwu, C.6
Sanna, V.7
Jebb, S.A.8
Perna, F.9
Fontana, S.10
-
20
-
-
65449170377
-
Leptin signaling: A key pathway in immune responses
-
Procaccini, C., E. V. Lourenco, G. Matarese, and A. La Cava. 2009. Leptin signaling: A key pathway in immune responses. Curr Signal Transduct Ther 4: 22-30.
-
(2009)
Curr Signal Transduct Ther
, vol.4
, pp. 22-30
-
-
Procaccini, C.1
Lourenco, E.V.2
Matarese, G.3
La Cava, A.4
-
21
-
-
63249135654
-
Three questions about leptin and immunity
-
Fantuzzi, G. 2009. Three questions about leptin and immunity. Brain Behav. Immun. 23: 405-410.
-
(2009)
Brain Behav. Immun.
, vol.23
, pp. 405-410
-
-
Fantuzzi, G.1
-
22
-
-
33744946045
-
Leptin receptor expression and signaling in lymphocytes: Kinetics during lymphocyte activation, role in lymphocyte survival, and response to high fat diet in mice
-
Papathanassoglou, E., K. El-Haschimi, X. C. Li, G. Matarese, T. Strom, and C. Mantzoros. 2006. Leptin receptor expression and signaling in lymphocytes: kinetics during lymphocyte activation, role in lymphocyte survival, and response to high fat diet in mice. J. Immunol. 176: 7745-7752.
-
(2006)
J. Immunol.
, vol.176
, pp. 7745-7752
-
-
Papathanassoglou, E.1
El-Haschimi, K.2
Li, X.C.3
Matarese, G.4
Strom, T.5
Mantzoros, C.6
-
23
-
-
0036378052
-
Leptin receptor (Ob-R) expression is induced in peripheral blood mononuclear cells by in vitro activation and in vivo in HIV-infected patients
-
Sánchez-Margalet, V., C. Martín-Romero, C. González-Yanes, R. Goberna, J. Rodríguez-Baño, and M. A. Muniain. 2002. Leptin receptor (Ob-R) expression is induced in peripheral blood mononuclear cells by in vitro activation and in vivo in HIV-infected patients. Clin. Exp. Immunol. 129: 119-124.
-
(2002)
Clin. Exp. Immunol.
, vol.129
, pp. 119-124
-
-
Sánchez-Margalet, V.1
Martín-Romero, C.2
González-Yanes, C.3
Goberna, R.4
Rodríguez-Baño, J.5
Muniain, M.A.6
-
24
-
-
1242270639
-
Leptin-induced signal transduction pathways
-
Hegyi, K., K. Fülöp, K. Kovács, S. Tóth, and A. Falus. 2004. Leptin-induced signal transduction pathways. Cell Biol. Int. 28: 159-169.
-
(2004)
Cell Biol. Int.
, vol.28
, pp. 159-169
-
-
Hegyi, K.1
Fülöp, K.2
Kovács, K.3
Tóth, S.4
Falus, A.5
-
25
-
-
0035885876
-
Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: Possible role of Sam68
-
Martín-Romero, C., and V. Sánchez-Margalet. 2001. Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68. Cell. Immunol. 212: 83-91.
-
(2001)
Cell. Immunol.
, vol.212
, pp. 83-91
-
-
Martín-Romero, C.1
Sánchez-Margalet, V.2
-
26
-
-
0035838266
-
Human leptin signaling in human peripheral blood mononuclear cells: Activation of the JAK-STAT pathway
-
Sanchez-Margalet, V., and C. Martin-Romero. 2001. Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway. Cell. Immunol. 211: 30-36.
-
(2001)
Cell. Immunol.
, vol.211
, pp. 30-36
-
-
Sanchez-Margalet, V.1
Martin-Romero, C.2
-
27
-
-
0038723695
-
Role of leptin as an immunomodulator of blood mononuclear cells: Mechanisms of action
-
Sánchez-Margalet, V., C. Martín-Romero, J. Santos-Alvarez, R. Goberna, S. Najib, and C. Gonzalez-Yanes. 2003. Role of leptin as an immunomodulator of blood mononuclear cells: mechanisms of action. Clin. Exp. Immunol. 133: 11-19.
-
(2003)
Clin. Exp. Immunol.
, vol.133
, pp. 11-19
-
-
Sánchez-Margalet, V.1
Martín-Romero, C.2
Santos-Alvarez, J.3
Goberna, R.4
Najib, S.5
Gonzalez-Yanes, C.6
-
28
-
-
78650188983
-
An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness
-
Procaccini, C., V. De Rosa, M. Galgani, L. Abanni, G. Calì, A. Porcellini, F. Carbone, S. Fontana, T. L. Horvath, A. La Cava, and G. Matarese. 2010. An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness. Immunity 33: 929-941.
-
(2010)
Immunity
, vol.33
, pp. 929-941
-
-
Procaccini, C.1
De Rosa, V.2
Galgani, M.3
Abanni, L.4
Calì, G.5
Porcellini, A.6
Carbone, F.7
Fontana, S.8
Horvath, T.L.9
La Cava, A.10
Matarese, G.11
-
29
-
-
0032572722
-
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
-
Lord, G. M., G. Matarese, J. K. Howard, R. J. Baker, S. R. Bloom, and R. I. Lechler. 1998. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394: 897-901.
-
(1998)
Nature
, vol.394
, pp. 897-901
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
Baker, R.J.4
Bloom, S.R.5
Lechler, R.I.6
-
30
-
-
33747799996
-
Indirect effects of leptin receptor deficiency on lymphocyte populations and immune response in db/db mice
-
Palmer, G., M. Aurrand-Lions, E. Contassot, D. Talabot-Ayer, D. Ducrest-Gay, C. Vesin, V. Chobaz-Péclat, N. Busso, and C. Gabay. 2006. Indirect effects of leptin receptor deficiency on lymphocyte populations and immune response in db/db mice. J. Immunol. 177: 2899-2907.
-
(2006)
J. Immunol.
, vol.177
, pp. 2899-2907
-
-
Palmer, G.1
Aurrand-Lions, M.2
Contassot, E.3
Talabot-Ayer, D.4
Ducrest-Gay, D.5
Vesin, C.6
Chobaz-Péclat, V.7
Busso, N.8
Gabay, C.9
-
31
-
-
34247874513
-
Effect of leptin on activation and cytokine synthesis in peripheral blood lymphocytes of malnourished infected children
-
Rodríguez, L., J. Graniel, and R. Ortiz. 2007. Effect of leptin on activation and cytokine synthesis in peripheral blood lymphocytes of malnourished infected children. Clin. Exp. Immunol. 148: 478-485.
-
(2007)
Clin. Exp. Immunol.
, vol.148
, pp. 478-485
-
-
Rodríguez, L.1
Graniel, J.2
Ortiz, R.3
-
32
-
-
0034628016
-
Human leptin enhances activation and proliferation of human circulating T lymphocytes
-
Martín-Romero, C., J. Santos-Alvarez, R. Goberna, and V. Sánchez-Margalet. 2000. Human leptin enhances activation and proliferation of human circulating T lymphocytes. Cell. Immunol. 199: 15-24.
-
(2000)
Cell. Immunol.
, vol.199
, pp. 15-24
-
-
Martín-Romero, C.1
Santos-Alvarez, J.2
Goberna, R.3
Sánchez- Margalet, V.4
-
33
-
-
78649972071
-
Generation of leptin receptor bone marrow chimeras: Recovery from irradiation, immune cellularity, cytokine expression, and metabolic parameters
-
Gove, M. E., C. L. Sherry, M. Pini, and G. Fantuzzi. 2010. Generation of leptin receptor bone marrow chimeras: recovery from irradiation, immune cellularity, cytokine expression, and metabolic parameters. Obesity (Silver Spring) 18: 2274-2281.
-
(2010)
Obesity (Silver Spring)
, vol.18
, pp. 2274-2281
-
-
Gove, M.E.1
Sherry, C.L.2
Pini, M.3
Fantuzzi, G.4
-
34
-
-
0036243107
-
Leptin inhibits stress-induced apoptosis of T lymphocytes
-
Fujita, Y., M. Murakami, Y. Ogawa, H. Masuzaki, M. Tanaka, S. Ozaki, K. Nakao, and T. Mimori. 2002. Leptin inhibits stress-induced apoptosis of T lymphocytes. Clin. Exp. Immunol. 128: 21-26.
-
(2002)
Clin. Exp. Immunol.
, vol.128
, pp. 21-26
-
-
Fujita, Y.1
Murakami, M.2
Ogawa, Y.3
Masuzaki, H.4
Tanaka, M.5
Ozaki, S.6
Nakao, K.7
Mimori, T.8
-
35
-
-
0029844267
-
Effect of fasting on serum leptin in normal human subjects
-
Boden, G., X. Chen, M. Mozzoli, and I. Ryan. 1996. Effect of fasting on serum leptin in normal human subjects. J. Clin. Endocrinol. Metab. 81: 3419-3423.
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 3419-3423
-
-
Boden, G.1
Chen, X.2
Mozzoli, M.3
Ryan, I.4
-
36
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima, R. S., D. Prabakaran, C. Mantzoros, D. Qu, B. Lowell, E. Maratos-Flier, and J. S. Flier. 1996. Role of leptin in the neuroendocrine response to fasting. Nature 382: 250-252.
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
Qu, D.4
Lowell, B.5
Maratos-Flier, E.6
Flier, J.S.7
-
37
-
-
0032741972
-
Leptin protects mice from starvationinduced lymphoid atrophy and increases thymic cellularity in ob/ob mice
-
Howard, J. K., G. M. Lord, G. Matarese, S. Vendetti, M. A. Ghatei, M. A. Ritter, R. I. Lechler, and S. R. Bloom. 1999. Leptin protects mice from starvationinduced lymphoid atrophy and increases thymic cellularity in ob/ob mice. J. Clin. Invest. 104: 1051-1059.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1051-1059
-
-
Howard, J.K.1
Lord, G.M.2
Matarese, G.3
Vendetti, S.4
Ghatei, M.A.5
Ritter, M.A.6
Lechler, R.I.7
Bloom, S.R.8
-
38
-
-
54249141095
-
Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival
-
Maciver, N. J., S. R. Jacobs, H. L. Wieman, J. A. Wofford, J. L. Coloff, and J. C. Rathmell. 2008. Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival. J. Leukoc. Biol. 84: 949-957.
-
(2008)
J. Leukoc. Biol.
, vol.84
, pp. 949-957
-
-
Maciver, N.J.1
Jacobs, S.R.2
Wieman, H.L.3
Wofford, J.A.4
Coloff, J.L.5
Rathmell, J.C.6
-
39
-
-
17044422629
-
Glucose availability regulates IFNgamma production and p70S6 kinase activation in CD8+ effector T cells
-
Cham, C. M., and T. F. Gajewski. 2005. Glucose availability regulates IFNgamma production and p70S6 kinase activation in CD8+ effector T cells. J. Immunol. 174: 4670-4677.
-
(2005)
J. Immunol.
, vol.174
, pp. 4670-4677
-
-
Cham, C.M.1
Gajewski, T.F.2
-
40
-
-
0032904873
-
Comparing effects of leptin and insulin on glucose metabolism in skeletal muscle: Evidence for an effect of leptin on glucose uptake and decarboxylation
-
Ceddia, R. B.,W. N.William, Jr., and R. Curi. 1999. Comparing effects of leptin and insulin on glucose metabolism in skeletal muscle: evidence for an effect of leptin on glucose uptake and decarboxylation. Int. J. Obes. Rel. Metab. Dis. 23: 75-82.
-
(1999)
Int. J. Obes. Rel. Metab. Dis.
, vol.23
, pp. 75-82
-
-
Ceddia, R.B.1
William Jr., W.N.2
Curi, R.3
-
41
-
-
30044448374
-
Direct metabolic regulation in skeletal muscle and fat tissue by leptin: Implications for glucose and fatty acids homeostasis
-
Ceddia, R. B. 2005. Direct metabolic regulation in skeletal muscle and fat tissue by leptin: implications for glucose and fatty acids homeostasis. Int. J. Obes. (Lond) 29: 1175-1183.
-
(2005)
Int. J. Obes. (Lond)
, vol.29
, pp. 1175-1183
-
-
Ceddia, R.B.1
-
42
-
-
0034904776
-
Growth factors can influence cell growth and survival through effects on glucose metabolism
-
Vander Heiden, M. G., D. R. Plas, J. C. Rathmell, C. J. Fox, M. H. Harris, and C. B. Thompson. 2001. Growth factors can influence cell growth and survival through effects on glucose metabolism. Mol. Cell. Biol. 21: 5899-5912.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5899-5912
-
-
Vander Heiden, M.G.1
Plas, D.R.2
Rathmell, J.C.3
Fox, C.J.4
Harris, M.H.5
Thompson, C.B.6
-
43
-
-
34247184208
-
Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking
-
Wieman, H. L., J. A. Wofford, and J. C. Rathmell. 2007. Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking. Mol. Biol. Cell 18: 1437-1446.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 1437-1446
-
-
Wieman, H.L.1
Wofford, J.A.2
Rathmell, J.C.3
-
44
-
-
41349093966
-
IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival
-
Wofford, J. A., H. L. Wieman, S. R. Jacobs, Y. Zhao, and J. C. Rathmell. 2008. IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival. Blood 111: 2101-2111.
-
(2008)
Blood
, vol.111
, pp. 2101-2111
-
-
Wofford, J.A.1
Wieman, H.L.2
Jacobs, S.R.3
Zhao, Y.4
Rathmell, J.C.5
-
45
-
-
24644456824
-
Glucose transporter 1 expression identifies a population of cycling CD4+ CD8+ human thymocytes with high CXCR4-induced chemotaxis
-
Swainson, L., S. Kinet, N. Manel, J. L. Battini, M. Sitbon, and N. Taylor. 2005. Glucose transporter 1 expression identifies a population of cycling CD4+ CD8+ human thymocytes with high CXCR4-induced chemotaxis. Proc. Natl. Acad. Sci. USA 102: 12867-12872.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 12867-12872
-
-
Swainson, L.1
Kinet, S.2
Manel, N.3
Battini, J.L.4
Sitbon, M.5
Taylor, N.6
-
46
-
-
32444449415
-
Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis
-
De Rosa, V., C. Procaccini, A. La Cava, P. Chieffi, G. F. Nicoletti, S. Fontana, S. Zappacosta, and G. Matarese. 2006. Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis. J. Clin. Invest. 116: 447-455.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 447-455
-
-
De Rosa, V.1
Procaccini, C.2
La Cava, A.3
Chieffi, P.4
Nicoletti, G.F.5
Fontana, S.6
Zappacosta, S.7
Matarese, G.8
-
47
-
-
84875464349
-
Cutting edge: Leptin-induced RORgt expression in CD4+ T cells promotes Th17 responses in systemic lupus erythematosus
-
Yu, Y., Y. Liu, F. D. Shi, H. Zou, G. Matarese, and A. La Cava. 2013. Cutting edge: Leptin-induced RORgt expression in CD4+ T cells promotes Th17 responses in systemic lupus erythematosus. J. Immunol. 190: 3054-3058.
-
(2013)
J. Immunol.
, vol.190
, pp. 3054-3058
-
-
Yu, Y.1
Liu, Y.2
Shi, F.D.3
Zou, H.4
Matarese, G.5
La Cava, A.6
-
48
-
-
84868129089
-
Leptin exacerbates collagen-induced arthritis via enhancement of Th17 cell response
-
Deng, J., Y. Liu, M. Yang, S. Wang, M. Zhang, X. Wang, K. H. Ko, Z. Hua, L. Sun, X. Cao, and L. Lu. 2012. Leptin exacerbates collagen-induced arthritis via enhancement of Th17 cell response. Arthritis Rheum. 64: 3564-3573.
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 3564-3573
-
-
Deng, J.1
Liu, Y.2
Yang, M.3
Wang, S.4
Zhang, M.5
Wang, X.6
Ko, K.H.7
Hua, Z.8
Sun, L.9
Cao, X.10
Lu, L.11
-
49
-
-
84870475160
-
T cell-derived leptin contributes to increased frequency of T helper type 17 cells in female patients with Hashimoto's thyroiditis
-
Wang, S., S. E. Baidoo, Y. Liu, C. Zhu, J. Tian, J. Ma, J. Tong, J. Chen, X. Tang, H. Xu, and L. Lu. 2013. T cell-derived leptin contributes to increased frequency of T helper type 17 cells in female patients with Hashimoto's thyroiditis. Clin. Exp. Immunol. 171: 63-68.
-
(2013)
Clin. Exp. Immunol.
, vol.171
, pp. 63-68
-
-
Wang, S.1
Baidoo, S.E.2
Liu, Y.3
Zhu, C.4
Tian, J.5
Ma, J.6
Tong, J.7
Chen, J.8
Tang, X.9
Xu, H.10
Lu, L.11
-
50
-
-
79151484704
-
Adipokines in inflammation and metabolic disease
-
Ouchi, N., J. L. Parker, J. J. Lugus, and K. Walsh. 2011. Adipokines in inflammation and metabolic disease. Nat. Rev. Immunol. 11: 85-97.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 85-97
-
-
Ouchi, N.1
Parker, J.L.2
Lugus, J.J.3
Walsh, K.4
-
51
-
-
84876248594
-
Childhood weight gain and thyroid autoimmunity at age 60-64 years: The 1946 British birth cohort study
-
Medical Research Council National Survey of Health and Development Scientific and Data Collection Teams.
-
Ong, K. K., D. Kuh, M. Pierce, and J. A. Franklyn; Medical Research Council National Survey of Health and Development Scientific and Data Collection Teams. 2013. Childhood weight gain and thyroid autoimmunity at age 60-64 years: the 1946 British birth cohort study. J. Clin. Endocrinol. Metab. 98: 1435-1442.
-
(2013)
J. Clin. Endocrinol. Metab.
, vol.98
, pp. 1435-1442
-
-
Ong, K.K.1
Kuh, D.2
Pierce, M.3
Franklyn, J.A.4
-
52
-
-
34548487258
-
The link between the epidemics of obesity and allergic diseases: Does obesity induce decreased immune tolerance?
-
Hersoug, L. G., and A. Linneberg. 2007. The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance? Allergy 62: 1205-1213.
-
(2007)
Allergy
, vol.62
, pp. 1205-1213
-
-
Hersoug, L.G.1
Linneberg, A.2
-
53
-
-
79955725584
-
Environmental factors and thyroid autoimmunity
-
Duntas, L. H. 2011. Environmental factors and thyroid autoimmunity. Ann. Endocrinol. (Paris) 72: 108-113.
-
(2011)
Ann. Endocrinol. (Paris)
, vol.72
, pp. 108-113
-
-
Duntas, L.H.1
-
54
-
-
84859140799
-
Metabolic pathways in T cell fate and function
-
Gerriets, V. A., and J. C. Rathmell. 2012. Metabolic pathways in T cell fate and function. Trends Immunol. 33: 168-173.
-
(2012)
Trends Immunol.
, vol.33
, pp. 168-173
-
-
Gerriets, V.A.1
Rathmell, J.C.2
-
55
-
-
66249108601
-
Understanding theWarburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden, M. G., L. C. Cantley, and C. B. Thompson. 2009. Understanding theWarburg effect: the metabolic requirements of cell proliferation. Science 324: 1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
56
-
-
84863202384
-
Molecular mechanisms of metabolic reprogramming in proliferating cells: Implications for T-cell-mediated immunity
-
Marelli-Berg, F. M., H. Fu, and C. Mauro. 2012. Molecular mechanisms of metabolic reprogramming in proliferating cells: implications for T-cell-mediated immunity. Immunology 136: 363-369.
-
(2012)
Immunology
, vol.136
, pp. 363-369
-
-
Marelli-Berg, F.M.1
Fu, H.2
Mauro, C.3
-
57
-
-
54249147709
-
Chronic calorie restriction attenuates experimental autoimmune encephalomyelitis
-
Piccio, L., J. L. Stark, and A. H. Cross. 2008. Chronic calorie restriction attenuates experimental autoimmune encephalomyelitis. J. Leukoc. Biol. 84: 940-948.
-
(2008)
J. Leukoc. Biol.
, vol.84
, pp. 940-948
-
-
Piccio, L.1
Stark, J.L.2
Cross, A.H.3
-
58
-
-
84863135746
-
Cutting edge: Fasting-induced hypoleptinemia expands functional regulatory T cells in systemic lupus erythematosus
-
Liu, Y., Y. Yu, G. Matarese, and A. La Cava. 2012. Cutting edge: fasting-induced hypoleptinemia expands functional regulatory T cells in systemic lupus erythematosus. J. Immunol. 188: 2070-2073.
-
(2012)
J. Immunol.
, vol.188
, pp. 2070-2073
-
-
Liu, Y.1
Yu, Y.2
Matarese, G.3
La Cava, A.4
-
59
-
-
84866168094
-
Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses
-
Procaccini, C., V. De Rosa, M. Galgani, F. Carbone, S. Cassano, D. Greco, K. Qian, P. Auvinen, G. Calì, G. Stallone, et al. 2012. Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses. J. Immunol. 189: 2941-2953.
-
(2012)
J. Immunol.
, vol.189
, pp. 2941-2953
-
-
Procaccini, C.1
De Rosa, V.2
Galgani, M.3
Carbone, F.4
Cassano, S.5
Greco, D.6
Qian, K.7
Auvinen, P.8
Calì, G.9
Stallone, G.10
-
60
-
-
33847312289
-
A key role of leptin in the control of regulatory T cell proliferation
-
De Rosa, V., C. Procaccini, G. Calì, G. Pirozzi, S. Fontana, S. Zappacosta, A. La Cava, and G. Matarese. 2007. A key role of leptin in the control of regulatory T cell proliferation. Immunity 26: 241-255.
-
(2007)
Immunity
, vol.26
, pp. 241-255
-
-
De Rosa, V.1
Procaccini, C.2
Calì, G.3
Pirozzi, G.4
Fontana, S.5
Zappacosta, S.6
La Cava, A.7
Matarese, G.8
-
61
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
Frauwirth, K. A., J. L. Riley, M. H. Harris, R. V. Parry, J. C. Rathmell, D. R. Plas, R. L. Elstrom, C. H. June, and C. B. Thompson. 2002. The CD28 signaling pathway regulates glucose metabolism. Immunity 16: 769-777.
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.A.1
Riley, J.L.2
Harris, M.H.3
Parry, R.V.4
Rathmell, J.C.5
Plas, D.R.6
Elstrom, R.L.7
June, C.H.8
Thompson, C.B.9
-
62
-
-
0027372655
-
Feast and famine: Critical role of glucocorticoids with insulin in daily energy flow
-
Dallman, M. F., A. M. Strack, S. F. Akana, M. J. Bradbury, E. S. Hanson, K. A. Scribner, and M. Smith. 1993. Feast and famine: critical role of glucocorticoids with insulin in daily energy flow. Front. Neuroendocrinol. 14: 303-347.
-
(1993)
Front. Neuroendocrinol.
, vol.14
, pp. 303-347
-
-
Dallman, M.F.1
Strack, A.M.2
Akana, S.F.3
Bradbury, M.J.4
Hanson, E.S.5
Scribner, K.A.6
Smith, M.7
-
63
-
-
2942692043
-
Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression
-
Makimura, H., T. M. Mizuno, F. Isoda, J. Beasley, J. H. Silverstein, and C. V. Mobbs. 2003. Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression. BMC Physiol. 3: 5.
-
(2003)
BMC Physiol.
, vol.3
, pp. 5
-
-
Makimura, H.1
Mizuno, T.M.2
Isoda, F.3
Beasley, J.4
Silverstein, J.H.5
Mobbs, C.V.6
-
64
-
-
3042833447
-
Overview of the actions of glucocorticoids on the immune response: A good model to characterize new pathways of immunosuppression for new treatment strategies
-
Franchimont, D. 2004. Overview of the actions of glucocorticoids on the immune response: a good model to characterize new pathways of immunosuppression for new treatment strategies. Ann. N. Y. Acad. Sci. 1024: 124-137.
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1024
, pp. 124-137
-
-
Franchimont, D.1
-
65
-
-
70349766380
-
Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution
-
Gruver, A. L., M. S. Ventevogel, and G. D. Sempowski. 2009. Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution. J. Endocrinol. 203: 75-85.
-
(2009)
J. Endocrinol.
, vol.203
, pp. 75-85
-
-
Gruver, A.L.1
Ventevogel, M.S.2
Sempowski, G.D.3
-
66
-
-
33845567333
-
Leptin: Nourishment for the immune system
-
Fantuzzi, G. 2006. Leptin: nourishment for the immune system. Eur. J. Immunol. 36: 3101-3104.
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 3101-3104
-
-
Fantuzzi, G.1
-
67
-
-
79958292985
-
Role of central leptin signaling in the starvation-induced alteration of B-cell development
-
Tanaka, M., T. Suganami, M. Kim-Saijo, C. Toda, M. Tsuiji, K. Ochi, Y. Kamei, Y. Minokoshi, and Y. Ogawa. 2011. Role of central leptin signaling in the starvation-induced alteration of B-cell development. J. Neurosci. 31: 8373-8380.
-
(2011)
J. Neurosci.
, vol.31
, pp. 8373-8380
-
-
Tanaka, M.1
Suganami, T.2
Kim-Saijo, M.3
Toda, C.4
Tsuiji, M.5
Ochi, K.6
Kamei, Y.7
Minokoshi, Y.8
Ogawa, Y.9
|