In vitro and in vivo evaluation of WGA-carbopol modified liposomes as carriers for oral peptide delivery

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 77, Issue 2, 2011, Pages 216-224

  Makhlof, Abdallah ^a,b   Fujimoto, Shiho ^a   Tozuka, Yuichi ^a   Takeuchi, Hirofumi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b ASSIUT UNIVERSITY   (Egypt)

Author keywords

Bioadhesion; Calcitonin; Lectins; Liposomes; Oral peptide delivery; Wheat germ agglutinin

Indexed keywords

CARBOMER; LIPOSOME; WHEAT GERM AGGLUTININ;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CELL STRAIN CACO 2; CYTOTOXICITY; DRUG DELIVERY SYSTEM; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; LIPID MEMBRANE; MALE; NONHUMAN; RAT; SURFACE PROPERTY; TEMPERATURE MEASUREMENT;

ADMINISTRATION, ORAL; ANIMALS; CACO-2 CELLS; CALCITONIN; CALCIUM; CELL SURVIVAL; HUMANS; INTESTINE, SMALL; LECTINS; LIPOSOMES; MALE; PARTICLE SIZE; POLYMERS; POLYVINYLS; RATS; RATS, WISTAR; WHEAT GERM AGGLUTININS;

EID: 79551528343     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.12.008     Document Type: Article

References (31)

1. K. Sonaje, Y.H. Lin, J.H. Juang, S.P. Wey, C.T. Chen, and H.W. Sung In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery Biomaterials 30 2009 2329 2339
2. L. Yin, J. Ding, C. He, L. Cui, C. Tang, and C. Yin Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery Biomaterials 30 2009 5691 5700
3. M. Werle, and H. Takeuchi Chitosan-aprotinin coated liposomes for oral peptide delivery: development, characterization and in vivo evaluation Int. J. Pharm. 370 2009 26 32
4. M. Werle, A. Makhlof, and H. Takeuchi Carbopol-lectin conjugate coated liposomes for oral peptide delivery Chem. Pharm. Bull. 58 2010 432 434
5. A. Makhlof, M. Werle, Y. Tozuka, H. Takeuchi, A mucoadhesive nanoparticulate system for the simultaneous delivery of macromolecules and permeation enhancers to the intestinal mucosa, J. Control. Release. doi: 10.1016/j.jconrel.2010.02.001.
6. A. des Rieux, V. Fievez, M. Garinot, Y.-J. Schneider, and V. Preat Nanoparticles as potential oral delivery systems of protein and vaccines: a mechanistic approach J. Control. Release 116 2006 1 27
7. T. Jung, W. Kamm, A. Breitenbach, E. Kaiserling, J.X. Xiao, and T. Kissel Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake Eur. J. Pharm. Biopharm. 50 2000 147 160
8. S.H. Liu, W.G. Mallet, and F.M. Brodskt Clathrin-mediated endocytosis M. Marsh, Endocytosis 2001 Oxford University Press New York 1 25
9. G.J. Russell-Jones The potential use of receptor-mediated endocytosis for oral drug delivery Adv. Drug Deliv. Rev. 46 2001 59 73
10. A.T. Florence The oral absorption of micro- and nanoparticulates: neither exceptional nor unusual Pharm. Res. 14 1997 259 266
11. A. Weissenbok, E. Bogner, M. Wirth, and F. Gabor Binding and uptake of wheat germ agglutinin-grafted PLGA-nanospheres by Caco-2 monolayers Pharm. Res. 21 2004 1917 1923
12. T. Minko Drug targeting to the colon with lectins and neoglycoconjugates Adv. Drug Deliv. Rev. 56 2004 491 509
13. C.-M. Lehr Lectin mediated drug delivery: the second generation of bioadhesives J. Control. Release 65 2000 19 29
14. C. Bies, C.-M. Lehr, and J.F. Woodley Lectin-mediated drug targeting: history and applications Adv. Drug Deliv. Rev. 56 2004 425 435
15. F. Gabor, A. Schwarzbauer, and M. Wirth Lectin-mediated drug delivery: binding and uptake of BSA-WGA conjugates using the Caco-2 model Int. J. Pharm. 237 2002 227 239
16. H. Takeuchi, Y. Matsui, H. Sugihara, H. Yamamoto, and Y. Kawashima Effectiveness of submicron-sized, chitosan-coated liposomes in oral administration of peptide drugs Int. J. Pharm. 303 2005 160 170
17. J. Thongborisute, A. Tsuruta, Y. Kawabata, and H. Takeuchi The effect of particle structure of chitosan-coated liposomes and type of chitosan on oral delivery of calcitonin J. Drug Target. 14 2006 147 154
18. B.-Y. Kim, J.H. Jeong, K. Park, and J.-D. Kim Bioadhesive interaction and hypoglycemic effect of insulin-loaded lectin-microparticle conjugates in oral insulin delivery system J. Control. Release 102 2005 525 538
19. N. Hussain, P.U. Jani, and A.T. Florence Enhanced oral uptake of tomato lectin-conjugated nanoparticles in the rat Pharm. Res. 14 1997 613 618
20. G.J. Russell-Jones, H. Veitch, and L. Arthur Lectin-mediated transport of nanoparticles across Caco-2 and OK cells Int. J. Pharm. 190 1999 165 174 (Pubitemid 29509910)
21. A. Weissenbok, M. Wirth, and F. Gabor WGA-grafted PLGA nanospheres: preparation and association with Caco-2 single cells J. Control. Release 99 2004 383 392
22. Y. Yin, D. Chen, M. Qiao, Z. Lu, and H. Hu Preparation and evaluation of lectin-conjugated PLGA nanoparticles for oral delivery of thymopentin J. Control. Release 116 2006 337 345
23. H.E. Junginger, and J.C. Verhoef Macromolecules as safe penetration enhancers for hydrophilic drugs - a fiction? Pharm. Sci. Technol. Today 1 1998 370 376
24. K. Nakano, Y. Tozuka, H. Yamamoto, Y. Kawashima, and H. Takeuchi A novel method for measuring the rigidity of submicron-sized liposomes with atomic force microscopy Int. J. Pharm. 355 2008 203 209
25. H. Takeuchi, Y. Matsui, H. Yamamoto, and Y. Kawashima Mucoadhesive properties of carbopol or chitosan-coated liposomes and their effectiveness in the oral administration of calcitonin to rats J. Control. Release 86 2003 235 242
26. A. Makhlof, M. Werle, and H. Takeuchi Mucoadhesive drug carriers and polymers for effective drug delivery Drug Deliv. Sci. Technol. 18 2008 375 386
27. M. Huang, Z. Ma, E. Khor, and L. Lim Uptake of FITC-CS nanoparticles by A549 cells Pharm. Res. 19 2002 1488 1494
28. M. Wirth, C. Kneuer, C.-M. Lehr, and F. Gabor Lectin-mediated drug delivery: discrimination between cytoadhesion and cytoinvasion and evidence for lysosomal accumulation of wheat germ agglutinin in the Caco-2 model J. Drug Target. 10 2002 439 448
29. M. Wirth, K. Gerhardt, C. Wurm, and F. Gabor Lectin-mediated drug delivery: influence of mucin on cytoadhesive of plant lectins in vitro J. Control. Release 79 2002 183 191
30. J.F. Forstner, and C.G. Forstner Gastrointestinal mucus L.R. Johnson, Physiology of the Gastrointestinal Tract 1994 Raven Press New York 1255 1283
31. H.L. Luessen, J.C. Verhoef, G. Borchard, C.-M. Lehr, A.G. de Boer, and H.E. Junginger Mucoadhesive polymers in peroral peptide drug delivery. II. Carbomer and polycarbophil are potent inhibitors of the intestinal proteolytic enzyme trypsin Pharm. Res. 12 1995 1293 1298