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Volumn 1, Issue , 2007, Pages 247-264

Cytokines Interact with the Blood-Brain Barrier

Author keywords

Brain vessels; Cytokines cross BBB; Cytokines interact with blood brain barrier; Cytokines known effects on endothelial cells; Cytokines permeate BBB; Enzymatic control; Hormonal control; Mechanisms; Neurodegenerative disorders; Regulation; Simple diffusion; Specific transport systems; Stroke; Vasculopathy

Indexed keywords

BLOOD-BRAIN BARRIER; CYTOKINES;

EID: 84890973537     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527611225.ch11     Document Type: Chapter
Times cited : (16)

References (86)
  • 1
    • 0036843258 scopus 로고    scopus 로고
    • Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury
    • Aoki, T., Sumii, T., Mori, T., Wang, X., Lo, E. H. 2002, Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury, Stroke 33, 2711-2717.
    • (2002) Stroke , vol.33 , pp. 2711-2717
    • Aoki, T.1    Sumii, T.2    Mori, T.3    Wang, X.4    Lo, E.H.5
  • 3
    • 0035478029 scopus 로고    scopus 로고
    • Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia
    • Asahi, M., Wang, X., Mori, T., Sumii, T., Jung, J.-C., Moskowitz, M.A., Fini, M. E., Lo, E.H. 2001, Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia, J. Neurosci. 21, 7724-7732.
    • (2001) J. Neurosci. , vol.21 , pp. 7724-7732
    • Asahi, M.1    Wang, X.2    Mori, T.3    Sumii, T.4    Jung, J.-C.5    Moskowitz, M.A.6    Fini, M.E.7    Lo, E.H.8
  • 4
    • 0035856861 scopus 로고    scopus 로고
    • Leukemia inhibitory factor by systemic administration rescues spinal motor neurons in the SOD1 G93A murine model of familial amyotrophic lateral sclerosis
    • Azari, M.F., Galle, A., Lopes, E. C., Kurek, J., Cheema, S. S. 2001, Leukemia inhibitory factor by systemic administration rescues spinal motor neurons in the SOD1 G93A murine model of familial amyotrophic lateral sclerosis, Brain Res. 922, 144-147.
    • (2001) Brain Res. , vol.922 , pp. 144-147
    • Azari, M.F.1    Galle, A.2    Lopes, E.C.3    Kurek, J.4    Cheema, S.S.5
  • 6
    • 0032530520 scopus 로고    scopus 로고
    • Role of the CNS microvascular pericyte in the blood-brain barrier
    • Balabanov, R., Dore-Duffy, P. 1998, Role of the CNS microvascular pericyte in the blood-brain barrier, J. Neurosci. Res. 53, 637-644.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 637-644
    • Balabanov, R.1    Dore-Duffy, P.2
  • 7
    • 0029934646 scopus 로고    scopus 로고
    • Reversible association of the cytokines MIP-1a and MIP-1b with the endothelia of the blood-brain barrier
    • Banks, W. A., Kastin, A. J. 1996, Reversible association of the cytokines MIP-1a and MIP-1b with the endothelia of the blood-brain barrier, Neurosci. Lett. 205, 202-206.
    • (1996) Neurosci. Lett. , vol.205 , pp. 202-206
    • Banks, W.A.1    Kastin, A.J.2
  • 8
    • 0024849292 scopus 로고
    • Bidirectional transport of interleukin-1 alpha across the blood-brain barrier
    • Banks, W. A., Kastin, A. J., Durham, D.A. 1989, Bidirectional transport of interleukin-1 alpha across the blood-brain barrier, Brain Res. Bull. 23, 433-437.
    • (1989) Brain Res. Bull. , vol.23 , pp. 433-437
    • Banks, W.A.1    Kastin, A.J.2    Durham, D.A.3
  • 9
    • 0027332621 scopus 로고
    • Interleukin-1α in blood has direct access to cortical brain cells
    • Banks, W. A., Kastin, A. J., Gutierrez, E.G. 1993, Interleukin-1α in blood has direct access to cortical brain cells, Neurosci. Lett. 163, 41-44.
    • (1993) Neurosci. Lett. , vol.163 , pp. 41-44
    • Banks, W.A.1    Kastin, A.J.2    Gutierrez, E.G.3
  • 10
    • 0028049995 scopus 로고
    • Penetration of interleukin-6 across the murine blood-brain barrier
    • Banks, W. A., Kastin, A. J., Gutierrez, E.G. 1994, Penetration of interleukin-6 across the murine blood-brain barrier, Neurosci. Lett. 179, 53-56.
    • (1994) Neurosci. Lett. , vol.179 , pp. 53-56
    • Banks, W.A.1    Kastin, A.J.2    Gutierrez, E.G.3
  • 11
    • 0034964745 scopus 로고    scopus 로고
    • Regional transport of TNF-α across the blood-brain barrier in young ICR and young and aged SAMP8 mice
    • Banks, W. A., Moinuddin, A., Morley, J. E. 2001, Regional transport of TNF-α across the blood-brain barrier in young ICR and young and aged SAMP8 mice, Neurobiol. Aging 22, 671-676.
    • (2001) Neurobiol. Aging , vol.22 , pp. 671-676
    • Banks, W.A.1    Moinuddin, A.2    Morley, J.E.3
  • 12
    • 0026334912 scopus 로고
    • Human interleukin (IL)1α, murine IL-1α and murine IL-1β are transported from blood to brain in the mouse by a shared saturable mechanism
    • Banks, W. A., Ortiz, L., Plotkin, S. R., Kastin, A. J. 1991, Human interleukin (IL)1α, murine IL-1α and murine IL-1β are transported from blood to brain in the mouse by a shared saturable mechanism, J. Pharmacol. Exp. Ther. 259, 988-996.
    • (1991) J. Pharmacol. Exp. Ther. , vol.259 , pp. 988-996
    • Banks, W.A.1    Ortiz, L.2    Plotkin, S.R.3    Kastin, A.J.4
  • 13
    • 0028881076 scopus 로고
    • Permeability of the blood-brain barrier to soluble cytokine receptors
    • Banks, W. A., Plotkin, S. R., Kastin, A. J. 1995, Permeability of the blood-brain barrier to soluble cytokine receptors Neuroimmunomodulation 2: 161-165.
    • (1995) Neuroimmunomodulation , vol.2 , pp. 161-165
    • Banks, W.A.1    Plotkin, S.R.2    Kastin, A.J.3
  • 14
    • 0028230288 scopus 로고
    • Vascular cell adhesion molecule-1 modulation by tumor necrosis factor in experimental allergic encephalomyelitis
    • Barten, D.M., Ruddle, N.H. 1994, Vascular cell adhesion molecule-1 modulation by tumor necrosis factor in experimental allergic encephalomyelitis, J. Neuroimmunol. 51, 123-133.
    • (1994) J. Neuroimmunol. , vol.51 , pp. 123-133
    • Barten, D.M.1    Ruddle, N.H.2
  • 17
    • 0037016137 scopus 로고    scopus 로고
    • MMP-9 and EBA immunoreactivity after papaverine mediated opening of the blood-brain barrier
    • Bhattacharjee, A. K., Kondoh, T., Ikeda, M., Kohmura, E. 2002, MMP-9 and EBA immunoreactivity after papaverine mediated opening of the blood-brain barrier, NeuroReport 13, 2217-2221.
    • (2002) NeuroReport , vol.13 , pp. 2217-2221
    • Bhattacharjee, A.K.1    Kondoh, T.2    Ikeda, M.3    Kohmura, E.4
  • 18
    • 0031470830 scopus 로고    scopus 로고
    • Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia
    • Botchkina, G. I., Meistrell, M.E. I., Botchkina, I. L., Tracey, K. J. 1997, Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia, Mol. Med. 3, 765-781.
    • (1997) Mol. Med. , vol.3 , pp. 765-781
    • Botchkina, G.I.1    Meistrell, M.E.I.2    Botchkina, I.L.3    Tracey, K.J.4
  • 19
    • 0025997208 scopus 로고
    • Tumor necrosis factor alters cytoskeletal organization and barrier function of endothelial cells
    • Camussi, G., Turello, E., Bussolino, F., Baglioni, C. 1991, Tumor necrosis factor alters cytoskeletal organization and barrier function of endothelial cells, Int. Arch. Allergy Appl. Immunol. 96, 84-91.
    • (1991) Int. Arch. Allergy Appl. Immunol. , vol.96 , pp. 84-91
    • Camussi, G.1    Turello, E.2    Bussolino, F.3    Baglioni, C.4
  • 20
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner, S. D., Schmid, S. L. 2003, Regulated portals of entry into the cell, Nature 422, 37-44.
    • (2003) Nature , vol.422 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 23
    • 0033526624 scopus 로고    scopus 로고
    • Upregulation of intercellular adhesion molecule-1 expression on human endothelial cells by tumour necrosis factor-alpha in an in vitro model of the blood-brain barrier
    • Dobbie, M.S., Hurst, R. D., Klein, N. J., Surtees, R. A. 1999, Upregulation of intercellular adhesion molecule-1 expression on human endothelial cells by tumour necrosis factor-alpha in an in vitro model of the blood-brain barrier, Brain Res. 830, 330-336.
    • (1999) Brain Res. , vol.830 , pp. 330-336
    • Dobbie, M.S.1    Hurst, R.D.2    Klein, N.J.3    Surtees, R.A.4
  • 24
    • 0027994105 scopus 로고
    • Cytokine-mediated activation of cultured CNS microvessels: a system for examining antigenic modulation of CNS endothelial cells, and evidence for long-term expression of the adhesion protein E-selectin
    • Dore-Duffy, P., Washington, R. A., Balabanov, R. 1994, Cytokine-mediated activation of cultured CNS microvessels: a system for examining antigenic modulation of CNS endothelial cells, and evidence for long-term expression of the adhesion protein E-selectin, J. Cereb. Blood Flow Metab. 14, 837-844.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 837-844
    • Dore-Duffy, P.1    Washington, R.A.2    Balabanov, R.3
  • 25
    • 0029004025 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor, microvascular hypermeability, and angiogenesis
    • Dvorak, H.F., Brown, L. F., Detmar, M., Dvorak, A.M. 1995, Vascular permeability factor/vascular endothelial growth factor, microvascular hypermeability, and angiogenesis, Am. J. Pathol. 146, 1029-1039.
    • (1995) Am. J. Pathol. , vol.146 , pp. 1029-1039
    • Dvorak, H.F.1    Brown, L.F.2    Detmar, M.3    Dvorak, A.M.4
  • 26
    • 0035500386 scopus 로고    scopus 로고
    • Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis
    • Elliott, J. L. 2001, Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis, Mol. Brain Res. 95, 172-178.
    • (2001) Mol. Brain Res. , vol.95 , pp. 172-178
    • Elliott, J.L.1
  • 27
    • 0028858595 scopus 로고
    • Effects of TNFα on the production of vasoactive substances by cerebral endothelial and smooth muscle cells in culture
    • Estrada, C., Gomez, C., Martin, C. 1995, Effects of TNFα on the production of vasoactive substances by cerebral endothelial and smooth muscle cells in culture, J. Cereb. Blood Flow Metab. 15, 920-928.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 920-928
    • Estrada, C.1    Gomez, C.2    Martin, C.3
  • 29
    • 0031798012 scopus 로고    scopus 로고
    • Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor
    • Gary, D. S., Bruce-Keller, A. J., Kindy, M. S., Mattson, M.P. 1998, Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor, J. Cereb. Blood Flow Metab. 18, 1283-1287.
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 1283-1287
    • Gary, D.S.1    Bruce-Keller, A.J.2    Kindy, M.S.3    Mattson, M.P.4
  • 30
    • 0034701007 scopus 로고    scopus 로고
    • Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis
    • Giess, R., Beck, M., Goetz, R., Nitsch, R. M., Toyka, K.V., Sendtner, M. 2000, Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis, Neurology 54, 1003-1005.
    • (2000) Neurology , vol.54 , pp. 1003-1005
    • Giess, R.1    Beck, M.2    Goetz, R.3    Nitsch, R.M.4    Toyka, K.V.5    Sendtner, M.6
  • 31
    • 0027517309 scopus 로고
    • Murine tumor necrosis factor alpha is transported from blood to brain in the mouse
    • Gutierrez, E. G., Banks, W. A., Kastin, A. J. 1993, Murine tumor necrosis factor alpha is transported from blood to brain in the mouse, J. Neuroimmunol. 47, 169-176.
    • (1993) J. Neuroimmunol. , vol.47 , pp. 169-176
    • Gutierrez, E.G.1    Banks, W.A.2    Kastin, A.J.3
  • 32
    • 0036908651 scopus 로고    scopus 로고
    • The many faces of tumor necrosis factor in stroke
    • Hallenbeck, J.M. 2002, The many faces of tumor necrosis factor in stroke, Nat. Med. 8, 1363-1368.
    • (2002) Nat. Med. , vol.8 , pp. 1363-1368
    • Hallenbeck, J.M.1
  • 35
    • 0036062628 scopus 로고    scopus 로고
    • Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G94A-SOD1 mouse model of amyotrophic lateral sclerosis
    • Hensley, K., Floyd, R. A., Gordon, B., Mou, S., Pye, Q.N., Stewart, C., West, M., Williamson, K. 2002, Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G94A-SOD1 mouse model of amyotrophic lateral sclerosis, J. Neurochem. 82, 365-374.
    • (2002) J. Neurochem. , vol.82 , pp. 365-374
    • Hensley, K.1    Floyd, R.A.2    Gordon, B.3    Mou, S.4    Pye, Q.N.5    Stewart, C.6    West, M.7    Williamson, K.8
  • 36
    • 0141442586 scopus 로고    scopus 로고
    • Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins
    • Hicke, L., Dunn, R. 2003, Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins, Annu. Rev. Cell Dev. Biol. 19, 141-172.
    • (2003) Annu. Rev. Cell Dev. Biol. , vol.19 , pp. 141-172
    • Hicke, L.1    Dunn, R.2
  • 37
    • 0033555395 scopus 로고    scopus 로고
    • TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1
    • Jones, S. J., Ledgerwood, E. C., Prins, J. B., Galbraith, J., Johnson, D.R., Pober, J. S., Bradley, J.R. 1999, TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1, J. Immunol. 162, 1042-1048.
    • (1999) J. Immunol. , vol.162 , pp. 1042-1048
    • Jones, S.J.1    Ledgerwood, E.C.2    Prins, J.B.3    Galbraith, J.4    Johnson, D.R.5    Pober, J.S.6    Bradley, J.R.7
  • 38
    • 0037785472 scopus 로고    scopus 로고
    • Interleukin-10 as a CNS therapeutic:the obstacle of the blood-brain/blood-spinal cord barrier
    • Kastin, A. J., Akerstrom, V., Pan, W. 2003, Interleukin-10 as a CNS therapeutic:the obstacle of the blood-brain/blood-spinal cord barrier, Mol. Brain Res. 114, 168-171.
    • (2003) Mol. Brain Res. , vol.114 , pp. 168-171
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 40
    • 6844266272 scopus 로고    scopus 로고
    • Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I study group
    • Lai, E. C., Felice, K. J., Festoff, B.W., Gawel, M.J., Gelinas, D.F., Murphy, M.F., Natter, H. M., Norris, F. H., Rudnicki, S. A. 1997, Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I study group, Neurology 49, 1621-1630.
    • (1997) Neurology , vol.49 , pp. 1621-1630
    • Lai, E.C.1    Felice, K.J.2    Festoff, B.W.3    Gawel, M.J.4    Gelinas, D.F.5    Murphy, M.F.6    Natter, H.M.7    Norris, F.H.8    Rudnicki, S.A.9
  • 41
    • 0021247422 scopus 로고    scopus 로고
    • Cerebrospinal fluid (CSF) findings in amyotrophic lateral sclerosis
    • Leonardi, A., Abbruzzese, G., Arata, L., Cocito, L., Vische, M. 1984, Cerebrospinal fluid (CSF) findings in amyotrophic lateral sclerosis, J. Neurol. 231, 75-78.
    • (1984) J. Neurol. , vol.231 , pp. 75-78
    • Leonardi, A.1    Abbruzzese, G.2    Arata, L.3    Cocito, L.4    Vische, M.5
  • 42
    • 0021247422 scopus 로고    scopus 로고
    • Cerebrospinal fluid (CSF) findings in amyotrophic lateral sclerosis
    • Leonardi, A., Abbruzzese, G., Arata, L., Cocito, L., Vische, M. 2004, Cerebrospinal fluid (CSF) findings in amyotrophic lateral sclerosis, J. Neurol. 231, 75-78.
    • (2004) J. Neurol. , vol.231 , pp. 75-78
    • Leonardi, A.1    Abbruzzese, G.2    Arata, L.3    Cocito, L.4    Vische, M.5
  • 43
    • 0029279164 scopus 로고
    • Insulin-like growth factor 1 treatment reduces clinical deficits and lesion severity in acute demyelinating experimental autoimmune encephalomyelitis
    • Liu, X., Yao, D.L., Webster, H. 1995, Insulin-like growth factor 1 treatment reduces clinical deficits and lesion severity in acute demyelinating experimental autoimmune encephalomyelitis, Mult. Scler. 1, 2-9.
    • (1995) Mult. Scler. , vol.1 , pp. 2-9
    • Liu, X.1    Yao, D.L.2    Webster, H.3
  • 44
    • 0028070678 scopus 로고
    • Lymphocyte migration into the CNS modelled in vitro: roles of LFA-1, ICAM-1 and VLA-4
    • Male, D., Rahman, J., Pryce, G., Tamatani, T., Miyasaka, M. 1994, Lymphocyte migration into the CNS modelled in vitro: roles of LFA-1, ICAM-1 and VLA-4, Immunology 81, 366-372.
    • (1994) Immunology , vol.81 , pp. 366-372
    • Male, D.1    Rahman, J.2    Pryce, G.3    Tamatani, T.4    Miyasaka, M.5
  • 45
    • 0035201474 scopus 로고    scopus 로고
    • Attenuation of ischemic brain edema and cerebrovascular injury after ischemic preconditioning in the rat
    • Masada, T., Hua, Y., Xi, G., Ennis, S. R., Keep, R. F. 2001, Attenuation of ischemic brain edema and cerebrovascular injury after ischemic preconditioning in the rat, J. Cereb. Blood Flow Metab. 21, 22-33.
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 22-33
    • Masada, T.1    Hua, Y.2    Xi, G.3    Ennis, S.R.4    Keep, R.F.5
  • 46
    • 0027407956 scopus 로고
    • Cytokine-regulated adhesion between encephalitogenic T lymphocytes and cerebrovascular endothelial cells
    • McCarron, R. M., Wang, L., Racke, M.K., McFarlin, D.E., Spatz, M. 1993, Cytokine-regulated adhesion between encephalitogenic T lymphocytes and cerebrovascular endothelial cells, J. Neuroimmunol. 43, 23-30.
    • (1993) J. Neuroimmunol. , vol.43 , pp. 23-30
    • McCarron, R.M.1    Wang, L.2    Racke, M.K.3    McFarlin, D.E.4    Spatz, M.5
  • 47
    • 0034528065 scopus 로고    scopus 로고
    • Passage of interleukin-1-beta across the blood-brain barrier is reduced in aged mice: a possible mechanism for diminished fever in aging
    • McLay, R. N., Kastin, A. J., Zadina, J. E. 2000, Passage of interleukin-1-beta across the blood-brain barrier is reduced in aged mice: a possible mechanism for diminished fever in aging, Neuroimmunomodulation 8, 148-153.
    • (2000) Neuroimmunomodulation , vol.8 , pp. 148-153
    • McLay, R.N.1    Kastin, A.J.2    Zadina, J.E.3
  • 49
    • 0028945672 scopus 로고
    • The role of trophic factors and autocrine/paracrine growth factors in brain metastasis
    • Menter, D. G., Herrmann, J. L., Nicolson, G. L. 1995, The role of trophic factors and autocrine/paracrine growth factors in brain metastasis, Clin. Exp. Metastasis 13, 67-88.
    • (1995) Clin. Exp. Metastasis , vol.13 , pp. 67-88
    • Menter, D.G.1    Herrmann, J.L.2    Nicolson, G.L.3
  • 50
    • 0031051349 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor and amelioration of brain infarction in mice
    • Nawashiro, H., Martin, D., Hallenbeck, J.M. 1997, Inhibition of tumor necrosis factor and amelioration of brain infarction in mice, J. Cereb. Blood Flow Metab. 17, 229-232.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 229-232
    • Nawashiro, H.1    Martin, D.2    Hallenbeck, J.M.3
  • 51
    • 0031005797 scopus 로고    scopus 로고
    • TNF-α pretreatment induces protective effects against focal cerebral ischemia in mice
    • Nawashiro, H., Tasaki, K., Ruetzler, C. A., Hallenbeck, J.M. 1997, TNF-α pretreatment induces protective effects against focal cerebral ischemia in mice, J. Cereb. Blood Flow Metab. 17, 483-490.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 483-490
    • Nawashiro, H.1    Tasaki, K.2    Ruetzler, C.A.3    Hallenbeck, J.M.4
  • 52
    • 3142683672 scopus 로고    scopus 로고
    • Modulation of feeding-related peptide/protein signals by the blood-brain barrier
    • Pan, W., Akerstrom, V., Zhang, J., Pejovic, V., Kastin, A. J. 2004, Modulation of feeding-related peptide/protein signals by the blood-brain barrier, J. Neurochem. 90, 455-461.
    • (2004) J. Neurochem. , vol.90 , pp. 455-461
    • Pan, W.1    Akerstrom, V.2    Zhang, J.3    Pejovic, V.4    Kastin, A.J.5
  • 53
    • 0030992694 scopus 로고    scopus 로고
    • Permeability of the blood-brain and blood-spinal cord barriers to interferons
    • Pan, W., Banks, W. A., Kastin, A. J. 1997, Permeability of the blood-brain and blood-spinal cord barriers to interferons, J. Neuroimmunol. 76, 105-111.
    • (1997) J. Neuroimmunol. , vol.76 , pp. 105-111
    • Pan, W.1    Banks, W.A.2    Kastin, A.J.3
  • 54
    • 0032579839 scopus 로고    scopus 로고
    • Permeability of the blood-brain barrier to neurotrophins
    • Pan, W., Banks, W. A., Kastin, A. J. 1998, Permeability of the blood-brain barrier to neurotrophins, Brain Res. 788, 87-94.
    • (1998) Brain Res. , vol.788 , pp. 87-94
    • Pan, W.1    Banks, W.A.2    Kastin, A.J.3
  • 55
    • 0029908222 scopus 로고    scopus 로고
    • Differential permeability of the BBB in acute EAE: enhanced transport of TNF-α
    • Pan, W., Banks, W. A., Kennedy, M. K., Gutierrez, E. G., Kastin, A. J. 1996, Differential permeability of the BBB in acute EAE: enhanced transport of TNF-α, Am. J. Physiol. 271, E636-E642.
    • (1996) Am. J. Physiol. , vol.271 , pp. E636-E642
    • Pan, W.1    Banks, W.A.2    Kennedy, M.K.3    Gutierrez, E.G.4    Kastin, A.J.5
  • 56
    • 84890973415 scopus 로고    scopus 로고
    • Receptormediated transport of LIF across blood-spinal cord barrier is upregulated after SCI
    • submitted
    • Pan, W., Cain, C., Tu, H., Yu, Y., Zhang, L., Kastin, A. J. 2005, Receptormediated transport of LIF across blood-spinal cord barrier is upregulated after SCI (submitted).
    • (2005)
    • Pan, W.1    Cain, C.2    Tu, H.3    Yu, Y.4    Zhang, L.5    Kastin, A.J.6
  • 57
    • 0036092644 scopus 로고    scopus 로고
    • Selected contribution:circadian rhythm of tumor necrosis factor-alpha uptake into mouse spinal cord
    • Pan, W., Cornelissen, G., Halberg, F., Kastin, A J. 2002, Selected contribution:circadian rhythm of tumor necrosis factor-alpha uptake into mouse spinal cord, J. Appl. Physiol. 92, 1357-1362.
    • (2002) J. Appl. Physiol. , vol.92 , pp. 1357-1362
    • Pan, W.1    Cornelissen, G.2    Halberg, F.3    Kastin, A.J.4
  • 59
    • 0242469194 scopus 로고    scopus 로고
    • Upregulation of p55 and p75 receptors mediating TNF-alpha transport across the injured blood-spinal cord barrier
    • Pan, W., Csernus, B., Kastin, A. J. 2003, Upregulation of p55 and p75 receptors mediating TNF-alpha transport across the injured blood-spinal cord barrier, J. Mol. Neurosci. 21, 173-184.
    • (2003) J. Mol. Neurosci. , vol.21 , pp. 173-184
    • Pan, W.1    Csernus, B.2    Kastin, A.J.3
  • 60
    • 0032871755 scopus 로고    scopus 로고
    • Entry of EGF into brain is rapid and saturable
    • Pan, W., Kastin, A. J. 1999, Entry of EGF into brain is rapid and saturable, Peptides 20, 1091-1098.
    • (1999) Peptides , vol.20 , pp. 1091-1098
    • Pan, W.1    Kastin, A.J.2
  • 61
    • 0033755363 scopus 로고    scopus 로고
    • Interactions of IGF-1 with the blood-brain barrier in vivo and in situ
    • Pan, W., Kastin, A. J. 2000, Interactions of IGF-1 with the blood-brain barrier in vivo and in situ, Neuroendocrinology 72, 171-178.
    • (2000) Neuroendocrinology , vol.72 , pp. 171-178
    • Pan, W.1    Kastin, A.J.2
  • 62
    • 0035795042 scopus 로고    scopus 로고
    • Changing the chemokine gradient: CINC1 crosses the blood-brain barrier
    • Pan, W., Kastin, A. J. 2001a, Changing the chemokine gradient: CINC1 crosses the blood-brain barrier, J. Neuroimmunol. 115, 64-70.
    • (2001) J. Neuroimmunol. , vol.115 , pp. 64-70
    • Pan, W.1    Kastin, A.J.2
  • 63
    • 0035805131 scopus 로고    scopus 로고
    • Diurnal variation of leptin entry from blood to brain involving partial saturation of the transport system
    • Pan, W., Kastin, A. J. 2001b, Diurnal variation of leptin entry from blood to brain involving partial saturation of the transport system, Life Sci. 68, 2705-2714.
    • (2001) Life Sci. , vol.68 , pp. 2705-2714
    • Pan, W.1    Kastin, A.J.2
  • 64
    • 0034741980 scopus 로고    scopus 로고
    • Increase in TNFα transport after SCI is specific for time, region, and type of lesion
    • Pan, W., Kastin, A. J. 2001c, Increase in TNFα transport after SCI is specific for time, region, and type of lesion, Exp. Neurol. 170, 357-363.
    • (2001) Exp. Neurol. , vol.170 , pp. 357-363
    • Pan, W.1    Kastin, A.J.2
  • 65
    • 0036009924 scopus 로고    scopus 로고
    • TNFα transport across the blood-brain barrier is abolished in receptor knockout mice
    • Pan, W., Kastin, A. J. 2002, TNFα transport across the blood-brain barrier is abolished in receptor knockout mice, Exp. Neurol. 174, 193-200.
    • (2002) Exp. Neurol. , vol.174 , pp. 193-200
    • Pan, W.1    Kastin, A.J.2
  • 66
    • 0037237881 scopus 로고    scopus 로고
    • Interactions of cytokines with the blood-brain barrier:implications for feeding
    • Pan, W., Kastin, A. J. 2003, Interactions of cytokines with the blood-brain barrier:implications for feeding, Curr. Pharm. Des. 9, 827-831.
    • (2003) Curr. Pharm. Des. , vol.9 , pp. 827-831
    • Pan, W.1    Kastin, A.J.2
  • 67
    • 0033135362 scopus 로고    scopus 로고
    • Upregulation of tumor necrosis factor α transport across the blood-brain barrier after acute compressive spinal cord injury
    • Pan, W., Kastin, A. J., Bell, R. L., Olson, R. D. 1999, Upregulation of tumor necrosis factor α transport across the blood-brain barrier after acute compressive spinal cord injury, J. Neurosci. 19, 3649-3655.
    • (1999) J. Neurosci. , vol.19 , pp. 3649-3655
    • Pan, W.1    Kastin, A.J.2    Bell, R.L.3    Olson, R.D.4
  • 68
    • 0034237420 scopus 로고    scopus 로고
    • Saturable entry of leukemia inhibitory factor from blood to the central nervous system
    • Pan, W., Kastin, A. J., Brennan, J.M. 2000, Saturable entry of leukemia inhibitory factor from blood to the central nervous system, J. Neuroimmunol. 106, 172-180.
    • (2000) J. Neuroimmunol. , vol.106 , pp. 172-180
    • Pan, W.1    Kastin, A.J.2    Brennan, J.M.3
  • 69
    • 0033582965 scopus 로고    scopus 로고
    • Saturable entry of ciliary neurotrophic factor into brain
    • Pan, W., Kastin, A. J., Maness, L. M., Brennan, J.M. 1999, Saturable entry of ciliary neurotrophic factor into brain, Neurosci. Lett. 263, 69-71.
    • (1999) Neurosci. Lett. , vol.263 , pp. 69-71
    • Pan, W.1    Kastin, A.J.2    Maness, L.M.3    Brennan, J.M.4
  • 70
    • 0032585709 scopus 로고    scopus 로고
    • TGFα and the blood-brain barrier:accumulation in cerebral vasculature
    • Pan, W., Vallance, K., Kastin, A. J. 1999, TGFα and the blood-brain barrier:accumulation in cerebral vasculature, Exp. Neurol. 160, 454-459.
    • (1999) Exp. Neurol. , vol.160 , pp. 454-459
    • Pan, W.1    Vallance, K.2    Kastin, A.J.3
  • 71
    • 84890972551 scopus 로고    scopus 로고
    • Direct and indirect interactions of growth hormone with the blood-brain barrier
    • in press
    • Pan, W., Yu, Y., Nyberg, F., Kastin, A. J. 2005, Direct and indirect interactions of growth hormone with the blood-brain barrier, Peptides 2005 (in press).
    • (2005) Peptides , pp. 2005
    • Pan, W.1    Yu, Y.2    Nyberg, F.3    Kastin, A.J.4
  • 73
    • 0037219053 scopus 로고    scopus 로고
    • Selective increase in TNFα permeation across the blood-spinal cord barrier after SCI
    • Pan, W., Zhang, L., Liao, J., Csernus, B., Kastin, A. J. 2003, Selective increase in TNFα permeation across the blood-spinal cord barrier after SCI, J. Neuroimmunol. 134, 111-117.
    • (2003) J. Neuroimmunol. , vol.134 , pp. 111-117
    • Pan, W.1    Zhang, L.2    Liao, J.3    Csernus, B.4    Kastin, A.J.5
  • 74
    • 0030176201 scopus 로고    scopus 로고
    • Comparison of saturable transport and extracellular pathways in the passage of interleukin-1α across the blood-brain barrier
    • Plotkin, S. R., Banks, W. A., Kastin, A. J. 1996, Comparison of saturable transport and extracellular pathways in the passage of interleukin-1α across the blood-brain barrier, J. Neuroimmunol. 67, 41-47.
    • (1996) J. Neuroimmunol. , vol.67 , pp. 41-47
    • Plotkin, S.R.1    Banks, W.A.2    Kastin, A.J.3
  • 75
    • 0029928170 scopus 로고    scopus 로고
    • Permeability at the blood-brain and bloodnerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF
    • Poduslo, J. F., Curran, G. L. 1996, Permeability at the blood-brain and bloodnerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF, Mol. Brain Res. 36, 280-286.
    • (1996) Mol. Brain Res. , vol.36 , pp. 280-286
    • Poduslo, J.F.1    Curran, G.L.2
  • 76
    • 0034733968 scopus 로고    scopus 로고
    • Circulating levels of tumor necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis
    • Poloni, M., Facchetti, D., Mai, R., Micheli, A., Agnoletti, L., Francolini, G., Mora, G., Camana, C., Mazzini, L., Bachetti, T. 2000, Circulating levels of tumor necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis, Neurosci. Lett. 287, 214.
    • (2000) Neurosci. Lett. , vol.287 , pp. 214
    • Poloni, M.1    Facchetti, D.2    Mai, R.3    Micheli, A.4    Agnoletti, L.5    Francolini, G.6    Mora, G.7    Camana, C.8    Mazzini, L.9    Bachetti, T.10
  • 77
    • 0032752452 scopus 로고    scopus 로고
    • Circadian phase-dependent antinociceptive reaction in mice determined by the hot-plate test and the tail-flick test after intravenous injection of dalargin-loaded nanoparticles
    • Ramge, P., Kreuter, J., Lemmer, B. 1999, Circadian phase-dependent antinociceptive reaction in mice determined by the hot-plate test and the tail-flick test after intravenous injection of dalargin-loaded nanoparticles, Chronobiol. Int. 16, 767-777.
    • (1999) Chronobiol. Int. , vol.16 , pp. 767-777
    • Ramge, P.1    Kreuter, J.2    Lemmer, B.3
  • 78
    • 0036737795 scopus 로고    scopus 로고
    • Matrix metalloproteinases in neuroinflammation
    • Rosenberg, G. A. 2002, Matrix metalloproteinases in neuroinflammation, Glia 39, 279-291.
    • (2002) Glia , vol.39 , pp. 279-291
    • Rosenberg, G.A.1
  • 81
    • 0022553592 scopus 로고
    • Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers
    • Stolphen, A. H., Guinan, E. C., Fiers, W., Pober, J.S. 1986, Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers, Am. J. Pathol. 123, 16-24.
    • (1986) Am. J. Pathol. , vol.123 , pp. 16-24
    • Stolphen, A.H.1    Guinan, E.C.2    Fiers, W.3    Pober, J.S.4
  • 82
    • 0037103742 scopus 로고    scopus 로고
    • The p55 tumor necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail
    • Storey, H., Stewart, A., Vandenabeele, P., Luzio, J. P. 2002, The p55 tumor necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail, Biochem. J. 366, 15-22.
    • (2002) Biochem. J. , vol.366 , pp. 15-22
    • Storey, H.1    Stewart, A.2    Vandenabeele, P.3    Luzio, J.P.4
  • 83
    • 0026578412 scopus 로고
    • Absorptive-mediated endocytosis of an adrenocorticotropic hormone (ACTH) analogue, ebiratide, into the blood-brain barrier: studies with monolayers of primary cultured bovine brain capillary endothelial cells
    • Terasaki, T., Takakuwa, S., Saheki, A., Moritani, S., Shimura, T., Tabata, S., Tsuji, A. 1992, Absorptive-mediated endocytosis of an adrenocorticotropic hormone (ACTH) analogue, ebiratide, into the blood-brain barrier: studies with monolayers of primary cultured bovine brain capillary endothelial cells, Pharm. Res. 9, 529-534.
    • (1992) Pharm. Res. , vol.9 , pp. 529-534
    • Terasaki, T.1    Takakuwa, S.2    Saheki, A.3    Moritani, S.4    Shimura, T.5    Tabata, S.6    Tsuji, A.7
  • 84
    • 0345824713 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein
    • Yepes, M., Sandkvist, M., Moore, E. G., Bugge, T. H., Strickland, D.K., Lawrence, D.A. 2003, Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein, J. Clin. Invest. 112, 1533-1540.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1533-1540
    • Yepes, M.1    Sandkvist, M.2    Moore, E.G.3    Bugge, T.H.4    Strickland, D.K.5    Lawrence, D.A.6
  • 85
    • 0036269810 scopus 로고    scopus 로고
    • Differential expression of inflammation-and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis
    • Yoshihara, T., Ishigaki, S., Yamamoto, M., Liang, Y., Niwa, J., Takeuchi, H., Doyu, M., Sobue, G. 2002, Differential expression of inflammation-and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis, J. Neurochem. 80, 158-167.
    • (2002) J. Neurochem. , vol.80 , pp. 158-167
    • Yoshihara, T.1    Ishigaki, S.2    Yamamoto, M.3    Liang, Y.4    Niwa, J.5    Takeuchi, H.6    Doyu, M.7    Sobue, G.8
  • 86
    • 0034651082 scopus 로고    scopus 로고
    • Role of tissue plasminogen activator receptor LRP in hippocampal long-term potentiation
    • Zhuo, M., Holtzman, D.M., Li, Y., Osaka, H., DeMaro, J., Jacquin, M., Bu, G. 2000, Role of tissue plasminogen activator receptor LRP in hippocampal long-term potentiation, J. Neurosci. 20, 542-549.
    • (2000) J. Neurosci. , vol.20 , pp. 542-549
    • Zhuo, M.1    Holtzman, D.M.2    Li, Y.3    Osaka, H.4    DeMaro, J.5    Jacquin, M.6    Bu, G.7


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