메뉴 건너뛰기




Volumn 114, Issue 2, 2003, Pages 168-171

Interleukin-10 as a CNS therapeutic: The obstacle of the blood-brain/blood-spinal cord barrier

Author keywords

Blood brain barrier; Cytokine; Hydrogen bonding; Interleukin 10; Lipophilicity

Indexed keywords

INTERLEUKIN 10;

EID: 0037785472     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(03)00167-0     Document Type: Article
Times cited : (43)

References (20)
  • 1
    • 0034757008 scopus 로고    scopus 로고
    • Intravenous human interleukin-1α impairs memory processing in mice: Dependence on blood-brain barrier transport into posterior division of the septum
    • Banks W.A., Farr S.A., La Scola M.E., Morley J.E. Intravenous human interleukin-1α impairs memory processing in mice: dependence on blood-brain barrier transport into posterior division of the septum. J. Pharmacol. Exp. Ther. 299:2001;536-541.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 536-541
    • Banks, W.A.1    Farr, S.A.2    La Scola, M.E.3    Morley, J.E.4
  • 2
    • 0030635748 scopus 로고    scopus 로고
    • Measurement of efflux rates from brain to blood
    • G.B. Irvine, Williams C.H. Totowa, NJ: Humana Press
    • Banks W.A., Fasold M.B., Kastin A.J. Measurement of efflux rates from brain to blood. Irvine G.B., Williams C.H. Methods in Molecular Biology, Neuropeptide Protocols. Vol. 73:1997;353-360 Humana Press, Totowa, NJ.
    • (1997) Methods in Molecular Biology, Neuropeptide Protocols , vol.73 , pp. 353-360
    • Banks, W.A.1    Fasold, M.B.2    Kastin, A.J.3
  • 3
    • 0027433633 scopus 로고
    • Interleukin 10 protects mice against staphylococcal enterotoxin B-induced lethal shock
    • Bean A.G.D., Freiberg R.A., Andrade S., Menon S., Zlotnik A. Interleukin 10 protects mice against staphylococcal enterotoxin B-induced lethal shock. Infect. Immun. 61:1993;4937-4939.
    • (1993) Infect. Immun. , vol.61 , pp. 4937-4939
    • Bean, A.G.D.1    Freiberg, R.A.2    Andrade, S.3    Menon, S.4    Zlotnik, A.5
  • 4
    • 0032739262 scopus 로고    scopus 로고
    • Systematically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats
    • Bethea J.R., Nagashima H., Acosta M.C., Briceno C., Gomez F., Marcillo A.E., Loor K., Green J., Dietrich W.D. Systematically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats. J. Neurotrauma. 16:1999;851.
    • (1999) J. Neurotrauma , vol.16 , pp. 851
    • Bethea, J.R.1    Nagashima, H.2    Acosta, M.C.3    Briceno, C.4    Gomez, F.5    Marcillo, A.E.6    Loor, K.7    Green, J.8    Dietrich, W.D.9
  • 5
    • 0028932174 scopus 로고
    • The effect of verapamil on the transport of peptides across the blood-brain barrier in rats: Kinetic evidence for an apically polarized efflux mechanism
    • Chikhale E.G., Burton P.S., Borchardt R.T. The effect of verapamil on the transport of peptides across the blood-brain barrier in rats: kinetic evidence for an apically polarized efflux mechanism. J. Pharmacol. Exp. Ther. 273:1995;298-303.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 298-303
    • Chikhale, E.G.1    Burton, P.S.2    Borchardt, R.T.3
  • 6
    • 0028783962 scopus 로고
    • Staphylococcal enterotoxin B and tumor-necrosis factor-α-induced relapses of experimental allergic encephalomyelitis: Protection by transforming growth factor-β and interleukin-10
    • Crisi G.M., Santambrogio L., Hochwald G.M., Smith S.R., Carlino J.A., Thorbecke G.J. Staphylococcal enterotoxin B and tumor-necrosis factor-α-induced relapses of experimental allergic encephalomyelitis: protection by transforming growth factor-β and interleukin-10. Eur. J. Immunol. 25:1995;3035-3040.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3035-3040
    • Crisi, G.M.1    Santambrogio, L.2    Hochwald, G.M.3    Smith, S.R.4    Carlino, J.A.5    Thorbecke, G.J.6
  • 7
    • 0035159581 scopus 로고    scopus 로고
    • Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis
    • Cua D.J., Hutchins B., LaFace D.M., Stohlman S.A., Coffman R.L. Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis. J. Immunol. 166:2001;602-608.
    • (2001) J. Immunol. , vol.166 , pp. 602-608
    • Cua, D.J.1    Hutchins, B.2    LaFace, D.M.3    Stohlman, S.A.4    Coffman, R.L.5
  • 8
    • 0030720919 scopus 로고    scopus 로고
    • Systemic interleukin 10 administration inhibits brain tumor necrosis factor production in mice
    • Di Santo E., Adami M., Bertorelli R., Ghezzi P. Systemic interleukin 10 administration inhibits brain tumor necrosis factor production in mice. Eur. J. Pharmacol. 336:1997;197-202.
    • (1997) Eur. J. Pharmacol. , vol.336 , pp. 197-202
    • Di Santo, E.1    Adami, M.2    Bertorelli, R.3    Ghezzi, P.4
  • 10
    • 1042283687 scopus 로고    scopus 로고
    • Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene
    • Hosoya K., Tetsuka K., Nagase K., Tomi M., Saeki S., Ohtsuki S., Terasaki T. Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene. AAPS Pharmsci. 2:2000;E27.
    • (2000) AAPS Pharmsci. , vol.2 , pp. 27
    • Hosoya, K.1    Tetsuka, K.2    Nagase, K.3    Tomi, M.4    Saeki, S.5    Ohtsuki, S.6    Terasaki, T.7
  • 11
    • 0027408695 scopus 로고
    • Interleukin-10 protects mice from lethal endotoxemia
    • Howard M., Muchamuel T., Andrade S., Menon S. Interleukin-10 protects mice from lethal endotoxemia. J. Exp. Med. 177:1993;1205-1208.
    • (1993) J. Exp. Med. , vol.177 , pp. 1205-1208
    • Howard, M.1    Muchamuel, T.2    Andrade, S.3    Menon, S.4
  • 12
    • 0035756597 scopus 로고    scopus 로고
    • Validity of multiple-time regression analysis in measurement of tritiated and iodinated leptin crossing the blood-brain barrier: Meaningful controls
    • Kastin A.J., Akerstrom V., Pan W. Validity of multiple-time regression analysis in measurement of tritiated and iodinated leptin crossing the blood-brain barrier: meaningful controls. Peptides. 22:2001;2127-2136.
    • (2001) Peptides , vol.22 , pp. 2127-2136
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 13
    • 0031713714 scopus 로고    scopus 로고
    • Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury
    • Knoblach S.M., Faden A.I. Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury. Exp. Neurol. 153:1998;143-151.
    • (1998) Exp. Neurol. , vol.153 , pp. 143-151
    • Knoblach, S.M.1    Faden, A.I.2
  • 14
    • 0030442779 scopus 로고    scopus 로고
    • Systemically (but not intrathecally) administered IL-10 attenuates pathophysiologic alterations in experimental pneumococcal meningitis
    • Koedel U., Bernatowicz A., Frei K., Fontana A., Pfister H.W. Systemically (but not intrathecally) administered IL-10 attenuates pathophysiologic alterations in experimental pneumococcal meningitis. J. Immunol. 157:1996;5185-5191.
    • (1996) J. Immunol. , vol.157 , pp. 5185-5191
    • Koedel, U.1    Bernatowicz, A.2    Frei, K.3    Fontana, A.4    Pfister, H.W.5
  • 15
    • 0035496978 scopus 로고    scopus 로고
    • Upregulation of the transport system for TNFα at the blood-brain barrier
    • Pan W., Kastin A.J. Upregulation of the transport system for TNFα at the blood-brain barrier. Arch. Physiol. Biochem. 109:2001;350-353.
    • (2001) Arch. Physiol. Biochem. , vol.109 , pp. 350-353
    • Pan, W.1    Kastin, A.J.2
  • 16
    • 0033526178 scopus 로고    scopus 로고
    • Penetration of neurotrophins and cytokines across the blood-brain/blood-spinal cord barrier
    • Pan W., Kastin A.J. Penetration of neurotrophins and cytokines across the blood-brain/blood-spinal cord barrier. Adv. Drug Deliv. Rev. 36:1999;291-298.
    • (1999) Adv. Drug Deliv. Rev. , vol.36 , pp. 291-298
    • Pan, W.1    Kastin, A.J.2
  • 17
    • 0020956774 scopus 로고
    • Graphical evaluation of blood-to-brain transfer constants from multiple time uptake data
    • Patlak C.S., Blasberg R.G., Fenstermacher J.D. Graphical evaluation of blood-to-brain transfer constants from multiple time uptake data. J. Cereb. Blood Flow Metab. 3:1983;1-7.
    • (1983) J. Cereb. Blood Flow Metab. , vol.3 , pp. 1-7
    • Patlak, C.S.1    Blasberg, R.G.2    Fenstermacher, J.D.3
  • 18
    • 0035126792 scopus 로고    scopus 로고
    • Effects of interleukin-10 (IL-10) on pain behavior and gene expression following excitotoxic spinal cord injury in the rat
    • Plunkett J.A., Yu C.G., Easton J.M., Bethea J.R., Yezierski R.P. Effects of interleukin-10 (IL-10) on pain behavior and gene expression following excitotoxic spinal cord injury in the rat. Exp. Neurol. 168:2001;144-154.
    • (2001) Exp. Neurol. , vol.168 , pp. 144-154
    • Plunkett, J.A.1    Yu, C.G.2    Easton, J.M.3    Bethea, J.R.4    Yezierski, R.P.5
  • 20
    • 0035109551 scopus 로고    scopus 로고
    • Conditionally immortalized cell lines as a new in vitro model for the study of barrier functions
    • Terasaki T., Hosoya K. Conditionally immortalized cell lines as a new in vitro model for the study of barrier functions. Biol. Pharm. Bull. 24:2001;111-118.
    • (2001) Biol. Pharm. Bull. , vol.24 , pp. 111-118
    • Terasaki, T.1    Hosoya, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.