Circadian phase-dependent antinociceptive reaction in mice determined by the hot-plate test and the tail-flick test after intravenous injection of dalargin-loaded nanoparticles

Chronobiology International

Volumn 16, Issue 6, 1999, Pages 767-777

  Ramge, Peter ^a   Kreuter, Jörg ^b   Lemmer, Björn ^b,c  

^a GOETHE UNIVERSITY   (Germany)

^b MEDICAL FACULTY MANNHEIM HEIDELBERG UNIVERSITY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Analgesia; Blood brain barrier; Circadian rhythm; Enkephalin analogue dalargin; Mice; Nanoparticles

Indexed keywords

LEUCINE ENKEPHALIN[2 DEXTRO ALANINE 6 ARGININE]; PHOSPHATE; POLYSORBATE 80; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BLOOD BRAIN BARRIER; CIRCADIAN RHYTHM; DOSE RESPONSE; HOT PLATE TEST; LATENT PERIOD; MOUSE; NONHUMAN; TAIL FLICK TEST;

ANIMALIA;

EID: 0032752452     PISSN: 07420528     EISSN: None     Source Type: Journal    
DOI: 10.3109/07420529909016944     Document Type: Article

References (24)

1. Abbott NJ, Romero, IA. 1996. Transporting therapeutics across the blood-brain barrier. Mol Med Today. March: 106-13.
2. Alyautdin R, Gothier D, Petrov V, et al. 1995. Analgesic activity of the hexapeptide dalargin adsorbed on the surface of polysorbate 80-coated poly(butyl cyanoacry-late) nanoparticles. Eur J Pharm Biopharm. 41:44-48.
3. Alyautdin RN, Petrov VE, Langer K, et al. 1997. Delivery of loperamide across the blood-brain-barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles. Pharm Res. 14:325-28.
4. Alyautdin RN, Tezikov EB, Ramge P, et al. 1998. Significant entry of tubocurarine into the brain of rats by adsorption to polysorbate 80-coated polybutylcyanoacrylate nanoparticles: an in vivo brain perfusion study. J Microencapsulation. 15:67-74.
5. Castellano C, Puglisi-Allegra S, Renzi P, et al. 1985. Genetic differences in daily rhythms of pain sensitivity in mice. Pharmacol Biochem Behav. 23:91-92.
6. D'Amour FE, Smith DL. 1941. A method for determining loss of pain sensation. J Pharmacol Exp Ther. 72:74-79.
7. Endo Y, Jinnai K, Endo M, et al. 1990. Diurnal variation of cerebral blood flow in rat hippocampus. Stroke. 21:1464-69.
8. Frederickson RCA, Burgis V, Edwards JD. 1977. Hyperalgesia induced by naloxone follows diurnal rhythm in responsivity to painful stimuli. Science. 198:756-58.
9. Kerdelhue B, Palkovits M, Kartezi M, et al. 1981. Circadian variations in substance P, luliberin (LH-RH) and thyroliberin (TRH) contents in hypothalamic and extrahypothalamic brain nuclei of adult male rats. Brain Res. 206:405-12.
10. Kreuter J, Alyautdin RN, Kharkevich DA, et al. 1995. Passages of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles). Brain Res. 674:171-74.
11. Kurumaji A, Takahashi M, Ohi K, et al. 1988. Circadian fluctuations in pain responsiveness and brain met-enkephalin-like immunoreactivity in the rat. Pharmacol Biochem Behav. 29:595-99.
12. Labrecque G, Karzazi M, Vanier M-C. 1997. Biological rhythms in pain and analgesia. In: Redfern P, Lemmer B, editors. Physiology and pharmacology of biological rhythms. Handbook of experimental pharmacology. Vol. 125. Heidelberg: Springer, pp. 619-19.
13. Labrecque G, Reinberg AE. 1989. Chronopharmacology of nonsteroid anti-inflammatory drugs. In: Lemmer B, editor. Chronopharmacology - cellular and biochemical interactions. New York: Marcel Dekker, pp. 545-79.
14. Maldonado R, Blendy JA, Tzavara E, et al. 1996. Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB. Science. 273:657-59.
15. Martinez-Gomez M, Cruz Y, Sala M, et al. 1994. Assessing pain threshold in the rat -changes with estrus and time of day. Physiol Behav. 55:651-57.
16. Mato M, Ookawara S, Tooyama K, et al. 1981. Chronobiological studies on the blood .brain barrier. Experientia. 37:1013-15.
17. Mattes A, Witte K, Hohmann W, et al. 1991. PHARMFIT - a nonlinear fitting program for pharmacology. Chronobiol Int. 8:460-76.
18. Naber D, Wirz-Justice A, Kafka MS. 1981. Circadian rhythm in rat brain opiate receptor. Neurosci Lett. 21:45-50.
19. Ramge P, von Briesen H, Oltrogge JB, et al. 1998. Entry of polysorbate 80-coated PBCA-nanoparticles into cultured brain capillary endothelial cells. Proc 2nd World Meeting Pharmaceutics, Biopharmaceutics, Pharmaceutical Technol. 599-600.
20. Redfern P, Lemmer B (editors). 1997. Physiology and pharmacology of biological rhythms. Handbook of experimental pharmacology. Vol. 125. Heidelberg: Springer.
21. Schlosberg AJ, Harvey JA. 1978. Diurnal changes in serotonin content of frontal lobe pole and pain sensitivity in the rat. Physiol Behav. 20:117-20.
22. Schröder U. Sabel BA. 1996. Nanoparticles, a drug carrier system to pass the blood-brain barrier, permit central analgesic effects of i.v. dalargin injections. Brain Res. 710:121-24.
23. Wesche L, Frederickson RCA. 1979. Diurnal differences in opioid peptide levels correlated with nociceptive sensitivity. Life Sci. 24:1861-68.
24. Wesche L, Frederickson RCA. 1981. The role of the pituitary in the diurnal variation in tolerance to painful stimuli and brain enkephalin levels. Life Sci. 29:2199-2205.