Thirteen-week oral dose toxicity study of Oligonol containing oligomerized polyphenols extracted from lychee and green tea

Regulatory Toxicology and Pharmacology

Volumn 68, Issue 1, 2014, Pages 140-146

  Kitadate, Kentaro ^a   Homma, Kohei ^a   Roberts, Ashley ^b   Maeda, Takahiro ^a  

^a Amino Up Chemical Co   (Japan)

^b Intertek Cantox   (Canada)

Author keywords

Catechin; Low molecular polyphenols; Nasal cavity; Oligonol; Toxicology

Indexed keywords

OLIGONOL; POLYPHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BODY WEIGHT; CONTROLLED STUDY; FECES COLOR; FEMALE; FOOD INTAKE; HISTOPATHOLOGY; LYCHEE; MALE; NONHUMAN; NOSE CAVITY; NOSE DISEASE; OLIGOMERIZATION; PRIORITY JOURNAL; RAT; REPEATED DRUG DOSE; TEA;

ANOVA; BODY WEIGHT; BW; CATECHIN; EGCG; EPIGALLOCATECHIN GALLATE; GREEN TEA EXTRACT; GTE; H&E; HEMATOXYLIN & EOSIN; IACUC; INSTITUTIONAL ANIMAL CARE AND USE COMMITTEES; LD(50); LFP; LOAEL; LOW MOLECULAR POLYPHENOLS; LOWEST-OBSERVED-ADVERSE-EFFECT LEVEL; LYCHEE FRUIT EXTRACT; MARGIN-OF-SAFETY; MEDIAN LETHAL DOSE; MOS; NASAL CAVITY; NO-OBSERVED-ADVERSE-EFFECT LEVEL; NOAEL; OLIGONOL; ONE-WAY ANALYSIS OF VARIANCE; TOXICOLOGY; ULTRAVIOLET; UV; V/V; VOLUME TO VOLUME;

ANIMALS; CAMELLIA SINENSIS; CATECHIN; FEMALE; FRUIT; LITCHI; MALE; NASAL CAVITY; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PHENOLS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; TOXICITY TESTS, SUBCHRONIC;

EID: 84890851352     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2013.12.001     Document Type: Article

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