Core assembly mechanism of quinocarcin/SF-1739: Bimodular complex nonribosomal peptide synthetases for sequential mannich-type reactions

Chemistry and Biology

Volumn 20, Issue 12, 2013, Pages 1523-1535

  Hiratsuka, Tomoshige ^a   Koketsu, Kento ^a   Minami, Atsushi ^a   Kaneko, Shunsuke ^a   Yamazaki, Chiaki ^a   Watanabe, Kenji ^b   Oguri, Hiroki ^a   Oikawa, Hideaki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; GENOMIC DNA; LONG CHAIN FATTY ACID; NONRIBOSOMAL PEPTIDE SYNTHETASE; PYROPHOSPHATE; PYRROLIDINE DERIVATIVE; QUINOCARCIN; SF 1739; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOSYNTHESIS; CHEMICAL ANALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; DEHYDROGENATION; ENZYME ACTIVITY; GENE CLUSTER; GENE INACTIVATION; GENETIC ENGINEERING; HYDROXYLATION; MANNICH REACTION; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; REGULATOR GENE; SEQUENCE HOMOLOGY;

ANTIBIOTICS, ANTINEOPLASTIC; BIOSYNTHETIC PATHWAYS; GENES, BACTERIAL; ISOQUINOLINES; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PEPTIDE SYNTHASES; QUINONES; STREPTOMYCES; TETRAHYDROISOQUINOLINES;

EID: 84890819425     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.10.011     Document Type: Article

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