Calpain 2 activation of P-TEFb drives megakaryocyte morphogenesis and is disrupted by leukemogenic GATA1 mutation

Developmental Cell

Volumn 27, Issue 6, 2013, Pages 607-620

  Elagib, KamaleldinE ^a   Rubinstein, JeremyD ^a   Delehanty, LorrieL ^a   Ngoh, ValerieS ^a   Greer, PeterA ^b   Li, Shuran ^a   Lee, JaeK ^a   Li, Zhe ^c,d   Orkin, StuartH ^c,d   Mihaylov, IvailoS ^a   Goldfarb, AdamN ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b QUEEN S UNIVERSITY   (Canada)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ 1; CALPAIN 2; P TEFB KINASE; PHOSPHOTRANSFERASE; SMALL NUCLEAR RIBONUCLEOPROTEIN; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DISSOLUTION; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMOGENESIS; MEGAKARYOCYTE; MEGAKARYOCYTIC LEUKEMIA; MEGAKARYOPOIESIS; MORPHOGENESIS; MOUSE; MUTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

EID: 84890813317     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2013.11.013     Document Type: Article

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