SRF-dependent gene expression in isolated cardiomyocytes: Regulation of genes involved in cardiac hypertrophy

Journal of Molecular and Cellular Cardiology

Volumn 39, Issue 3, 2005, Pages 479-489

  Nelson, Timothy J ^a   Balza Jr , Robert ^a   Xiao, Qi ^a   Misra, Ravi P ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Cardiac hypertrophy; Gene expression; SRF

Indexed keywords

ALPHA ACTIN; ATRIAL NATRIURETIC FACTOR; MYOSIN HEAVY CHAIN; MYOSIN HEAVY CHAIN ALPHA; MYOSIN HEAVY CHAIN BETA; PROTEIN C FOS; SERUM RESPONSE FACTOR; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ADAPTATION; ALLELE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE OVEREXPRESSION; HEART FAILURE; HEART MUSCLE CELL; HEART STRESS; HEART VENTRICLE HYPERTROPHY; IN VIVO STUDY; MOUSE; NEWBORN; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; TRANSGENIC MOUSE; TRANSGENICS;

ACTINS; ADENOVIRIDAE; ANIMALS; ANIMALS, NEWBORN; ATRIAL NATRIURETIC FACTOR; CARDIOMEGALY; CELLS, CULTURED; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HEART VENTRICLES; LUCIFERASES; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; NATRIURETIC PEPTIDE, BRAIN; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERUM RESPONSE FACTOR; SODIUM-CALCIUM EXCHANGER;

ANIMALIA; MUS MUSCULUS;

EID: 23644456010     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2005.05.004     Document Type: Article

References (41)

1. H.W. Davey, J.K. Kelly, and A.G. Wildeman The nucleotide sequence, structure, and preliminary studies on the transcriptional regulation of the bovine alpha skeletal actin gene DNA Cell Biol. 14 7 1995 609 618
2. T.A. Gustafson, and L. Kedes Identification of multiple proteins that interact with functional regions of the human cardiac alpha-actin promoter Mol. Cell. Biol. 9 8 1989 3269 3283
3. S.A. Henderson, M. Spencer, A. Sen, C. Kumar, M.A. Siddiqui, and K.R. Chien Structure, organization, and expression of the rat cardiac myosin light chain-2 gene. Identification of a 250-base pair fragment which confers cardiac-specific expression J. Biol. Chem. 264 30 1989 18142 18148
4. K. Huang, J.M. Louis, L. Donaldson, F.L. Lim, A.D. Sharrocks, and G.M. Clore Solution structure of the MEF2A-DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factors EMBO J. 19 11 2000 2615 2628
5. J.D. Molkentin, S.M. Jobe, and B.E. Markham Alpha-myosin heavy chain gene regulation: delineation and characterization of the cardiac muscle-specific enhancer and muscle-specific promoter J. Mol. Cell. Cardiol. 28 6 1996 1211 1225
6. S. Argentin, A. Ardati, S. Tremblay, I. Lihrmann, L. Robitaille, and J. Drouin Developmental stage-specific regulation of atrial natriuretic factor gene transcription in cardiac cells Mol. Cell. Biol. 14 1 1994 777 790
7. 2+ exchanger gene J. Biol. Chem. 274 18 1999 12819 12826
8. M.C. Schaub, M.A. Hefti, B.A. Harder, and H.M. Eppenberger Various hypertrophic stimuli induce distinct phenotypes in cardiomyocytes J. Mol. Med. 75 11-12 1997 901 920
9. W.A. Hines, J. Thorburn, and A. Thorburn A low-affinity serum response element allows other transcription factors to activate inducible gene expression in cardiac myocytes Mol. Cell. Biol. 19 3 1999 1841 1852
10. A.B. Sprenkle, S.F. Murray, and C.C. Glembotski Involvement of multiple cis elements in basal- and alpha-adrenergic agonist-inducible atrial natriuretic factor transcription. Roles for serum response elements and an SP-1-like element Circ. Res. 77 6 1995 1060 1069
11. D.J. Thuerauf, N.D. Arnold, D. Zechner, D.S. Hanford, K.M. DeMartin, and P.M. McDonough p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6 J. Biol. Chem. 273 32 1998 20636 20643
12. M.D. Schneider, W.R. McLellan, F.M. Black, and T.G. Parker Growth factors, growth factor response elements, and the cardiac phenotype Basic Res. Cardiol. 87 Suppl 2 1992 33 48
13. R. Treisman, and G. Ammerer The SRF and MCM1 transcription factors Curr. Opin. Genet. Dev. 2 2 1992 221 226
14. X.G. Lu, G. Azhar, L. Liu, H. Tsou, and J.Y. Wei SRF binding to SRE in the rat heart: influence of age J. Gerontol. A Biol. Sci. Med. Sci. 53 1 1998 B3 B10
15. M. Gupta, F.J. Davis, D. Jayakar, and V. Jeevananadam A dominant negative isoform of the serum-response factor (SRF) is increased in the failing human heart J. Heart Lung Transplant. 20 2 2001 160
16. J. Chang, L. Wei, T. Otani, K. Youker, M. Entman, and R.J. Schwartz Inhibitory cardiac transcription factor, SRF-N, is generated by caspase 3 cleavage in human heart failure and attenuated by ventricular unloading Circulation 108 4 2003 407 413
17. P.R. Kemp, and J.C. Metcalfe Four isoforms of serum response factor that increase or inhibit smooth-muscle-specific promoter activity Biochem. J. 345 Pt 3 2000 445 451
18. N.S. Belaguli, W. Zhou, T.H. Trinh, M.W. Majesky, and R.J. Schwartz Dominant negative murine serum response factor: alternative splicing within the activation domain inhibits transactivation of serum response factor binding targets Mol. Cell. Biol. 19 7 1999 4582 4591
19. X. Zhang, G. Azhar, J. Chai, P. Sheridan, K. Nagano, and T. Brown Cardiomyopathy in transgenic mice with cardiac-specific overexpression of serum response factor Am. J. Physiol. Heart Circ. Physiol. 280 4 2001 H1782 H1792
20. F. Chen, H. Kook, R. Milewski, A.D. Gitler, M.M. Lu, and J. Li Hop is an unusual homeobox gene that modulates cardiac development Cell 110 6 2002 713 723
21. C.H. Shin, Z.P. Liu, R. Passier, C.L. Zhang, D.Z. Wang, and T.M. Harris Modulation of cardiac growth and development by HOP, an unusual homeodomain protein Cell 110 6 2002 725 735
22. H. Kook, J. Lepore, A. Geitler, M. Lu, W. Wing-Man Yung, and J. Mackay Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop J. Clin. Invest. 112 6 2003 863 871
23. H.E. Shubeita, P.M. McDonough, A.N. Harris, K.U. Knowlton, C.C. Glembotski, and J.H. Brown Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy J. Biol. Chem. 265 33 1990 20555 20562
24. C.E. Seidman, K.D. Bloch, J. Zisfein, J.A. Smith, E. Haber, and C. Homcy Molecular studies of the atrial natriuretic factor gene Hypertension 7 3 Pt 2 1985 I31 I34
25. J.A. Spencer, and R.P. Misra Expression of the serum response factor gene is regulated by serum response factor binding sites J. Biol. Chem. 271 28 1996 16535 16543
26. J.M. Miano, N. Ramanan, M.A. Georger, K.L. de Mesy Bentley, R.L. Emerson, and R.O. Balza Jr. Restricted inactivation of serum response factor to the cardiovascular system Proc. Natl. Acad. Sci. USA 101 49 2004 17132 17137
27. D.E. Stec, R.L. Davisson, R.E. Haskell, B.L. Davidson, and C.D. Sigmund Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of Cre recombinase in vivo J. Biol. Chem. 274 30 1999 21285 21290
28. J.G. Muller, J.T. Thompson, A.M. Edmonson, M.S. Rackley, H. Kasahara, and S. Izumo Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor J. Mol. Cell. Cardiol. 34 7 2002 807 821
29. X. Deng, G. Rokosh, and P. Simpson Autonomous and growth factor-induced hypertrophy in cultured neonatal mouse cardiac myocytes: comparison with rat Circ. Res. 87 2000 781 788
30. R. Prywes, and H. Zhu In vitro squelching of activated transcription by serum response factor: evidence for a common coactivator used by multiple transcriptional activators Nucleic Acids Res. 20 3 1992 513 520
31. V. Joliot, M. Demma, and R. Prywes Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor Nature 373 6515 1995 632 635
32. H. Zhu, A.L. Roy, R.G. Roeder, and R. Prywes Serum response factor affects preinitiation complex formation by TFIID in vitro New Biol. 3 5 1991 455 464
33. J.M. Miano Serum response factor: toggling between disparate programs of gene expression J. Mol. Cell. Cardiol. 35 6 2003 577 593
34. A. Sotiropoulos, D. Gineitis, J. Copeland, and R. Treisman Signal-regulated activation of serum response factor is mediated by changes in actin dynamics Cell 98 2 1999 159 169
35. M. Torrado, E. Lopez, A. Centeno, C. Medrano, A. Castro-Beiras, and A. Mikkailov Myocardin mRNA is augmented in the failing myocardium: expression profiling in the porcine model and human dilated cardiomyopathy J. Mol. Med. 81 9 2003 566 577
36. J.L. Sepulveda, N. Belaguli, V. Nigam, C.Y. Chen, M. Nemer, and R.J. Schwartz GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression Mol. Cell. Biol. 18 6 1998 3405 3415
37. N.S. Belaguli, J.L. Sepulveda, V. Nigam, F. Charron, M. Nemer, and R.J. Schwartz Cardiac tissue enriched factors serum response factor and GATA-4 are mutual coregulators Mol. Cell. Biol. 20 20 2000 7550 7558
38. T. Morimoto, K. Hasegawa, S. Kaburagi, T. Kakita, H. Wada, and T. Yanazume Phosphorylation of GATA-4 is involved in alpha 1-adrenergic agonist-responsive transcription of the endothelin-1 gene in cardiac myocytes J. Biol. Chem. 275 18 2000 13721 13726
39. R.D. Searcy, E.B. Vincent, C.M. Liberatore, and K.E. Yutzey A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice Development 125 22 1998 4461 4470
40. J.L. Sepulveda, S. Vlahopoulos, D. Iyer, N. Belaguli, and R.J. Schwartz Combinatorial expression of GATA4, Nkx2-5, and serum response factor directs early cardiac gene activity J. Biol. Chem. 277 28 2002 25775 25782
41. Q. Liang, R.J. Wiese, O.F. Bueno, Y.S. Dai, B.E. Markham, and J.D. Molkentin The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes Mol. Cell. Biol. 21 21 2001 7460 7469