The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Krueger, Brian J ^a   Varzavand, Katayoun ^a   Cooper, Jeffrey J ^a   Price, David H ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRD4 PROTEIN; HEXIM1 PROTEIN; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PROTEIN; PROTEIN ANTIBODY; SMALL NUCLEAR RIBONUCLEOPROTEIN; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; BRD4 PROTEIN, HUMAN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HEXIM1 PROTEIN, HUMAN; NUCLEAR PROTEIN; RNA BINDING PROTEIN; SMALL NUCLEAR RNA; TRANSCRIPTION FACTOR;

ARTICLE; ASSAY; CELL LYSATE; CHEMICAL MODIFICATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME RELEASE; EXTRACTION; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; PROMOTER REGION; PROTEIN ASSEMBLY; PROTEIN DEPLETION; PROTEIN RNA BINDING; PROTEIN SECRETION; SEDIMENTATION; CHEMISTRY; CONFORMATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

BASE SEQUENCE; GENE EXPRESSION REGULATION; HELA CELLS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HIV-1; HUMANS; NUCLEAR PROTEINS; NUCLEIC ACID CONFORMATION; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN CONFORMATION; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA, SMALL NUCLEAR; RNA-BINDING PROTEINS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TRANSCRIPTION FACTORS;

EID: 77957880315     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012335     Document Type: Article

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