-
1
-
-
20444411532
-
Second nature: Biological functions of the Raf-1 "kinase"
-
1:CAS:528:DC%2BD2MXltFSqu74%3D 10.1016/j.febslet.2005.03.024
-
M Baccarini 2005 Second nature: biological functions of the Raf-1 "kinase" FEBS Lett 579 3271 3277 1:CAS:528:DC%2BD2MXltFSqu74%3D 10.1016/j.febslet.2005.03.024
-
(2005)
FEBS Lett
, vol.579
, pp. 3271-3277
-
-
Baccarini, M.1
-
2
-
-
33846489550
-
Apoptosis induced by crocidolite asbestos in human lung epithelial cells involves inactivation of Akt and MAPK pathways
-
1:CAS:528:DC%2BD2sXptFeksA%3D%3D 10.1007/s10495-006-0577-8
-
A Baldys P Pande T Mosleh SH Park AE Aust 2007 Apoptosis induced by crocidolite asbestos in human lung epithelial cells involves inactivation of Akt and MAPK pathways Apoptosis 12 433 447 1:CAS:528:DC%2BD2sXptFeksA%3D%3D 10.1007/s10495-006-0577-8
-
(2007)
Apoptosis
, vol.12
, pp. 433-447
-
-
Baldys, A.1
Pande, P.2
Mosleh, T.3
Park, S.H.4
Aust, A.E.5
-
3
-
-
0035984941
-
YC-1 increases cyclo-oxygenase-2 expression through protein kinase G- and p44/42 mitogen-activated protein kinase-dependent pathways in A549 cells
-
1:CAS:528:DC%2BD38XlsFWqtrg%3D 10.1038/sj.bjp.0704777
-
MS Chang WS Lee CM Teng HM Lee JR Sheu G Hsiao CH Lin 2002 YC-1 increases cyclo-oxygenase-2 expression through protein kinase G- and p44/42 mitogen-activated protein kinase-dependent pathways in A549 cells Br J Pharmacol 136 558 567 1:CAS:528:DC%2BD38XlsFWqtrg%3D 10.1038/sj.bjp.0704777
-
(2002)
Br J Pharmacol
, vol.136
, pp. 558-567
-
-
Chang, M.S.1
Lee, W.S.2
Teng, C.M.3
Lee, H.M.4
Sheu, J.R.5
Hsiao, G.6
Lin, C.H.7
-
4
-
-
79151480325
-
Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice
-
23 Oct 2009 (Epub ahead of print)
-
Colon J, Basha MR, Madero-Visbal R, Konduri S, Baker CH, Herrera LJ, Safe S, Sheikh-Hamad D, Abudayyeh A, Alvarado B, Abdelrahim M (2009) Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice. Invest New Drugs, 23 Oct 2009 (Epub ahead of print)
-
(2009)
Invest New Drugs
-
-
Colon, J.1
Basha, M.R.2
Madero-Visbal, R.3
Konduri, S.4
Baker, C.H.5
Herrera, L.J.6
Safe, S.7
Sheikh-Hamad, D.8
Abudayyeh, A.9
Alvarado, B.10
Abdelrahim, M.11
-
5
-
-
33947423401
-
Inhibition action of bufalin on human transplanted hepatocellular tumor and its effects on expressions of Bcl-2 and Bax proteins in nude mice
-
1:CAS:528:DC%2BD2sXksFKmt7o%3D 10.3736/jcim20070211
-
W Gu KQ Han YH Su XQ Huang CQ Ling 2007 Inhibition action of bufalin on human transplanted hepatocellular tumor and its effects on expressions of Bcl-2 and Bax proteins in nude mice Zhong Xi Yi Jie He Xue Bao 5 155 159 1:CAS:528:DC%2BD2sXksFKmt7o%3D 10.3736/jcim20070211
-
(2007)
Zhong Xi Yi Jie He Xue Bao
, vol.5
, pp. 155-159
-
-
Gu, W.1
Han, K.Q.2
Su, Y.H.3
Huang, X.Q.4
Ling, C.Q.5
-
6
-
-
41349099104
-
Cancer statistics, 2008
-
10.3322/CA.2007.0010
-
A Jemal R Siegel E Ward Y Hao J Xu T Murray MJ Thun 2008 Cancer statistics, 2008 CA Cancer J Clin 58 71 96 10.3322/CA.2007.0010
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
7
-
-
0034901568
-
Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage i non-small cell lung cancer
-
1:CAS:528:DC%2BD3MXjs1els7o%3D
-
FR Khuri H Wu JJ Lee BL Kemp R Lotan SM Lippman L Feng WK Hong XC Xu 2001 Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer Clin Cancer Res 7 861 867 1:CAS:528: DC%2BD3MXjs1els7o%3D
-
(2001)
Clin Cancer Res
, vol.7
, pp. 861-867
-
-
Khuri, F.R.1
Wu, H.2
Lee, J.J.3
Kemp, B.L.4
Lotan, R.5
Lippman, S.M.6
Feng, L.7
Hong, W.K.8
Xu, X.C.9
-
8
-
-
48849095238
-
MicroRNA miR-199a regulates the MET proto-oncogene and the downstream extracellular signal-regulated kinase 2 (ERK2)
-
1:CAS:528:DC%2BD1cXnsVCgu7k%3D 10.1074/jbc.M800186200
-
S Kim UJ Lee MN Kim EJ Lee JY Kim MY Lee S Choung YJ Kim YC Choi 2008 MicroRNA miR-199a regulates the MET proto-oncogene and the downstream extracellular signal-regulated kinase 2 (ERK2) J Biol Chem 283 18158 18166 1:CAS:528:DC%2BD1cXnsVCgu7k%3D 10.1074/jbc.M800186200
-
(2008)
J Biol Chem
, vol.283
, pp. 18158-18166
-
-
Kim, S.1
Lee, U.J.2
Kim, M.N.3
Lee, E.J.4
Kim, J.Y.5
Lee, M.Y.6
Choung, S.7
Kim, Y.J.8
Choi, Y.C.9
-
9
-
-
0029113707
-
Expression of p53 oncoprotein in non-small-cell lung cancer: A favorable prognostic factor
-
1:CAS:528:DyaK2MXntlKktbY%3D
-
JS Lee A Yoon SK Kalapurakal JY Ro JJ Lee N Tu WN Hittelman WK Hong 1995 Expression of p53 oncoprotein in non-small-cell lung cancer: a favorable prognostic factor J Clin Oncol 13 1893 1903 1:CAS:528:DyaK2MXntlKktbY%3D
-
(1995)
J Clin Oncol
, vol.13
, pp. 1893-1903
-
-
Lee, J.S.1
Yoon, A.2
Kalapurakal, S.K.3
Ro, J.Y.4
Lee, J.J.5
Tu, N.6
Hittelman, W.N.7
Hong, W.K.8
-
10
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
1:CAS:528:DyaK2sXhtFahtLg%3D 10.1016/S0092-8674(00)81871-1
-
AJ Levine 1997 p53, the cellular gatekeeper for growth and division Cell 88 323 331 1:CAS:528:DyaK2sXhtFahtLg%3D 10.1016/S0092-8674(00)81871-1
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
11
-
-
0037118905
-
Lipoteichoic acid-induced cyclooxygenase-2 expression requires activations of p44/42 and p38 mitogen-activated protein kinase signal pathways
-
1:CAS:528:DC%2BD38XmtlKjsb4%3D 10.1016/S0014-2999(02)02002-2
-
CH Lin IH Kuan CH Wang HM Lee WS Lee JR Sheu G Hsiao CH Wu HP Kuo 2002 Lipoteichoic acid-induced cyclooxygenase-2 expression requires activations of p44/42 and p38 mitogen-activated protein kinase signal pathways Eur J Pharmacol 450 1 9 1:CAS:528:DC%2BD38XmtlKjsb4%3D 10.1016/S0014-2999(02)02002-2
-
(2002)
Eur J Pharmacol
, vol.450
, pp. 1-9
-
-
Lin, C.H.1
Kuan, I.H.2
Wang, C.H.3
Lee, H.M.4
Lee, W.S.5
Sheu, J.R.6
Hsiao, G.7
Wu, C.H.8
Kuo, H.P.9
-
12
-
-
70449524216
-
Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells
-
1:CAS:528:DC%2BD1MXhtlCjsLjF 10.1007/s10616-009-9223-y
-
Q Liu H Duan J Luan K Yagasaki G Zhang 2009 Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells Cytotechnology 59 211 217 1:CAS:528:DC%2BD1MXhtlCjsLjF 10.1007/s10616-009-9223-y
-
(2009)
Cytotechnology
, vol.59
, pp. 211-217
-
-
Liu, Q.1
Duan, H.2
Luan, J.3
Yagasaki, K.4
Zhang, G.5
-
13
-
-
79951681028
-
Inhibitory effects of norcantharidin against human lung cancer cell growth and migration
-
20 Jan 2010 (Epub ahead of print)
-
Luan J, Duan H, Liu Q, Yagasaki K, Zhang G (2010) Inhibitory effects of norcantharidin against human lung cancer cell growth and migration. Cytotechnology 20 Jan 2010 (Epub ahead of print)
-
(2010)
Cytotechnology
-
-
Luan, J.1
Duan, H.2
Liu, Q.3
Yagasaki, K.4
Zhang, G.5
-
14
-
-
0037057629
-
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
-
1:CAS:528:DC%2BD38Xns1Ont70%3D 10.1038/nature01101
-
VS Marsden L O'Connor LA O'Reilly J Silke D Metcalf PG Ekert DC Huang F Cecconi K Kuida KJ Tomaselli S Roy DW Nicholson DL Vaux P Bouillet JM Adams A Strasser 2002 Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome Nature 419 634 637 1:CAS:528:DC%2BD38Xns1Ont70%3D 10.1038/nature01101
-
(2002)
Nature
, vol.419
, pp. 634-637
-
-
Marsden, V.S.1
O'Connor, L.2
O'Reilly, L.A.3
Silke, J.4
Metcalf, D.5
Ekert, P.G.6
Huang, D.C.7
Cecconi, F.8
Kuida, K.9
Tomaselli, K.J.10
Roy, S.11
Nicholson, D.W.12
Vaux, D.L.13
Bouillet, P.14
Adams, J.M.15
Strasser, A.16
-
15
-
-
0035949588
-
A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
-
1:CAS:528:DC%2BD3MXnt12js7s%3D 10.1073/pnas.181181198
-
LD Mayo DB Donner 2001 A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus Proc Natl Acad Sci USA 98 11598 11603 1:CAS:528:DC%2BD3MXnt12js7s%3D 10.1073/pnas.181181198
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11598-11603
-
-
Mayo, L.D.1
Donner, D.B.2
-
16
-
-
34248563290
-
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
-
1:CAS:528:DC%2BD2sXlt1WktLs%3D 10.1038/sj.onc.1210414
-
S Meloche J Pouysségur 2007 The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition Oncogene 26 3227 3239 1:CAS:528:DC%2BD2sXlt1WktLs%3D 10.1038/sj.onc.1210414
-
(2007)
Oncogene
, vol.26
, pp. 3227-3239
-
-
Meloche, S.1
Pouysségur, J.2
-
17
-
-
70449376872
-
Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer
-
10.1002/cncr.24602
-
Z Meng P Yang Y Shen W Bei Y Zhang Y Ge RA Newman L Cohen L Liu B Thornton DZ Chang Z Liao R Kurzrock 2009 Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer Cancer 115 5309 5318 10.1002/cncr.24602
-
(2009)
Cancer
, vol.115
, pp. 5309-5318
-
-
Meng, Z.1
Yang, P.2
Shen, Y.3
Bei, W.4
Zhang, Y.5
Ge, Y.6
Newman, R.A.7
Cohen, L.8
Liu, L.9
Thornton, B.10
Chang, D.Z.11
Liao, Z.12
Kurzrock, R.13
-
18
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
-
1:CAS:528:DyaK2cXkslCqurc%3D
-
T Miyashita S Krajewski M Krajewska HG Wang HK Lin DA Liebermann B Hoffman JC Reed 1994 Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo Oncogene 9 1799 1805 1:CAS:528: DyaK2cXkslCqurc%3D
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
Hoffman, B.7
Reed, J.C.8
-
19
-
-
33745590870
-
Anti-tumor activity of the combination of cetuximab, an anti-EGFR blocking monoclonal antibody and ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinases
-
1:CAS:528:DC%2BD28XmvVKisbc%3D 10.1002/jcp.20666
-
MP Morelli T Cascone T Troiani C Tuccillo R Bianco N Normanno M Romano BM Veneziani G Fontanini SG Eckhardt S De Pacido G Tortora F Ciardiello 2006 Anti-tumor activity of the combination of cetuximab, an anti-EGFR blocking monoclonal antibody and ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinases Cell Physiol 208 344 353 1:CAS:528:DC%2BD28XmvVKisbc%3D 10.1002/jcp.20666
-
(2006)
Cell Physiol
, vol.208
, pp. 344-353
-
-
Morelli, M.P.1
Cascone, T.2
Troiani, T.3
Tuccillo, C.4
Bianco, R.5
Normanno, N.6
Romano, M.7
Veneziani, B.M.8
Fontanini, G.9
Eckhardt, S.G.10
De Pacido, S.11
Tortora, G.12
Ciardiello, F.13
-
20
-
-
66149163097
-
Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance
-
1:CAS:528:DC%2BD1MXmtVKlsr0%3D 10.1158/1078-0432.CCR-08-2904
-
GN Naumov MB Nilsson T Cascone A Briggs O Straume LA Akslen E Lifshits LA Byers L Xu HK Wu P Jänne S Kobayashi B Halmos D Tenen XM Tang J Engelman B Yeap J Folkman BE Johnson JV Heymach 2009 Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance Clin Cancer Res 15 3484 3494 1:CAS:528:DC%2BD1MXmtVKlsr0%3D 10.1158/1078-0432.CCR-08-2904
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3484-3494
-
-
Naumov, G.N.1
Nilsson, M.B.2
Cascone, T.3
Briggs, A.4
Straume, O.5
Akslen, L.A.6
Lifshits, E.7
Byers, L.A.8
Xu, L.9
Wu, H.K.10
Jänne, P.11
Kobayashi, S.12
Halmos, B.13
Tenen, D.14
Tang, X.M.15
Engelman, J.16
Yeap, B.17
Folkman, J.18
Johnson, B.E.19
Heymach, J.V.20
more..
-
21
-
-
2442623486
-
The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells
-
1:CAS:528:DC%2BD2cXjsVektbc%3D 10.1093/carcin/bgh052
-
TT Nguyen E Tran TH Nguyen PT Do TH Huynh H Huynh 2004 The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells Carcinogenesis 25 647 659 1:CAS:528: DC%2BD2cXjsVektbc%3D 10.1093/carcin/bgh052
-
(2004)
Carcinogenesis
, vol.25
, pp. 647-659
-
-
Nguyen, T.T.1
Tran, E.2
Nguyen, T.H.3
Do, P.T.4
Huynh, T.H.5
Huynh, H.6
-
22
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
1:CAS:528:DyaK3sXms1eqtbs%3D 10.1016/0092-8674(93)90509-O
-
ZN Oltvai CL Milliman SJ Korsmeyer 1993 Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death Cell 74 609 619 1:CAS:528:DyaK3sXms1eqtbs%3D 10.1016/0092-8674(93)90509-O
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
24
-
-
0033304945
-
The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation
-
1:CAS:528:DyaK1MXlvVOnsbw%3D 10.1210/er.20.4.501
-
RG Pestell C Albanese AT Reutens JE Segall RJ Lee A Arnold 1999 The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation Endocr Rev 20 501 534 1:CAS:528: DyaK1MXlvVOnsbw%3D 10.1210/er.20.4.501
-
(1999)
Endocr Rev
, vol.20
, pp. 501-534
-
-
Pestell, R.G.1
Albanese, C.2
Reutens, A.T.3
Segall, J.E.4
Lee, R.J.5
Arnold, A.6
-
25
-
-
64849086921
-
Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer
-
10.4103/1477-3163.44372
-
N Puri R Salgia 2008 Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer J Carcinog 7 9 10.4103/1477-3163. 44372
-
(2008)
J Carcinog
, vol.7
, pp. 9
-
-
Puri, N.1
Salgia, R.2
-
26
-
-
58149310646
-
A cross-talk between the androgen receptor and the epidermal growth factor receptor leads to p38MAPK-dependent activation of mTOR and cyclinD1 expression in prostate and lung cancer cells
-
1:CAS:528:DC%2BD1MXns1yjtg%3D%3D 10.1016/j.biocel.2008.07.004
-
AG Recchia AM Musti M Lanzino ML Panno E Turano R Zumpano A Belfiore S Andò M Maggiolini 2009 A cross-talk between the androgen receptor and the epidermal growth factor receptor leads to p38MAPK-dependent activation of mTOR and cyclinD1 expression in prostate and lung cancer cells Int J Biochem Cell Biol 41 603 614 1:CAS:528:DC%2BD1MXns1yjtg%3D%3D 10.1016/j.biocel.2008.07.004
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 603-614
-
-
Recchia, A.G.1
Musti, A.M.2
Lanzino, M.3
Panno, M.L.4
Turano, E.5
Zumpano, R.6
Belfiore, A.7
Andò, S.8
Maggiolini, M.9
-
27
-
-
0031464448
-
Bcl-2 family proteins: Regulators of apoptosis and chemoresistance inhematologic malignancies
-
JC Reed 1997 Bcl-2 family proteins: regulators of apoptosis and chemoresistance inhematologic malignancies Semin Hematol 34 S9 S19
-
(1997)
Semin Hematol
, vol.34
-
-
Reed, J.C.1
-
28
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
-
1:CAS:528:DC%2BD2sXlt1Wktb4%3D 10.1038/sj.onc.1210422
-
PJ Roberts CJ Der 2007 Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer Oncogene 26 3291 3310 1:CAS:528:DC%2BD2sXlt1Wktb4%3D 10.1038/sj.onc.1210422
-
(2007)
Oncogene
, vol.26
, pp. 3291-3310
-
-
Roberts, P.J.1
Der, C.J.2
-
29
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
-
1:CAS:528:DC%2BD2cXlsl2hu7Y%3D 10.1128/MMBR.68.2.320-344.2004
-
PP Roux J Blenis 2004 ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions Microbiol Mol Biol Rev 68 320 344 1:CAS:528:DC%2BD2cXlsl2hu7Y%3D 10.1128/MMBR.68.2.320-344.2004
-
(2004)
Microbiol Mol Biol Rev
, vol.68
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
-
30
-
-
0033588217
-
Phosphoinositide 3-OH kinase (PI3 K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis
-
1:CAS:528:DyaK1MXlsVOnurc%3D 10.1074/jbc.274.34.24263
-
P Sabbatini F McCormick 1999 Phosphoinositide 3-OH kinase (PI3 K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis J Biol Chem 274 24263 24269 1:CAS:528:DyaK1MXlsVOnurc%3D 10.1074/jbc.274.34.24263
-
(1999)
J Biol Chem
, vol.274
, pp. 24263-24269
-
-
Sabbatini, P.1
McCormick, F.2
-
31
-
-
3242771185
-
Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of i kappa B alpha kinase and Akt in human non-small cell lung carcinoma: Correlation with suppression of COX-2 synthesis
-
1:CAS:528:DC%2BD2cXlvVajt74%3D
-
S Shishodia D Koul BB Aggarwal 2004 Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis J Immunol 173 2011 2022 1:CAS:528:DC%2BD2cXlvVajt74%3D
-
(2004)
J Immunol
, vol.173
, pp. 2011-2022
-
-
Shishodia, S.1
Koul, D.2
Aggarwal, B.B.3
-
32
-
-
0034615555
-
Caspases-controlling intracellular signals by protease zymogen activation
-
1:CAS:528:DC%2BD3cXhsFGktbk%3D
-
HR Stennicke GS Salvesen 2000 Caspases-controlling intracellular signals by protease zymogen activation Biochim Biophys Acta 1477 299 306 1:CAS:528:DC%2BD3cXhsFGktbk%3D
-
(2000)
Biochim Biophys Acta
, vol.1477
, pp. 299-306
-
-
Stennicke, H.R.1
Salvesen, G.S.2
-
33
-
-
74749094579
-
Naphtho[1, 2-b]furan-4, 5-dione inactivates EGFR and PI3 K/Akt signaling pathways in human lung adenocarcinoma A549 cells
-
1:CAS:528:DC%2BC3cXhtVKitrw%3D 10.1016/j.lfs.2009.12.006
-
JC Su KL Lin CM Chien CH Tseng YL Chen LS Chang SR Lin 2010 Naphtho[1, 2-b]furan-4, 5-dione inactivates EGFR and PI3 K/Akt signaling pathways in human lung adenocarcinoma A549 cells Life Sci 86 207 213 1:CAS:528: DC%2BC3cXhtVKitrw%3D 10.1016/j.lfs.2009.12.006
-
(2010)
Life Sci
, vol.86
, pp. 207-213
-
-
Su, J.C.1
Lin, K.L.2
Chien, C.M.3
Tseng, C.H.4
Chen, Y.L.5
Chang, L.S.6
Lin, S.R.7
-
34
-
-
46449105600
-
Bufalin induces growth inhibition, cell cycle arrest and apoptosis in human endometrial and ovarian cancer cells
-
1:CAS:528:DC%2BD1cXmt1amtLY%3D
-
N Takai T Ueda M Nishida K Nasu H Narahara 2008 Bufalin induces growth inhibition, cell cycle arrest and apoptosis in human endometrial and ovarian cancer cells Int J Mol Med 21 637 643 1:CAS:528:DC%2BD1cXmt1amtLY%3D
-
(2008)
Int J Mol Med
, vol.21
, pp. 637-643
-
-
Takai, N.1
Ueda, T.2
Nishida, M.3
Nasu, K.4
Narahara, H.5
-
35
-
-
0036674617
-
Live or let die: The cell's response to p53
-
1:CAS:528:DC%2BD38XlslGqsL8%3D 10.1038/nrc864
-
KH Vousden X Lu 2002 Live or let die: the cell's response to p53 Nat Rev Cancer 2 594 604 1:CAS:528:DC%2BD38XlslGqsL8%3D 10.1038/nrc864
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
36
-
-
0029003061
-
Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases
-
1:CAS:528:DyaK2MXmvVKjs74%3D 10.1038/376088a0
-
Y Wang C Prives 1995 Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases Nature 376 88 91 1:CAS:528:DyaK2MXmvVKjs74%3D 10.1038/376088a0
-
(1995)
Nature
, vol.376
, pp. 88-91
-
-
Wang, Y.1
Prives, C.2
-
37
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
-
1:CAS:528:DyaK28XmsFOhu7Y%3D 10.1126/science.274.5288.784
-
CY Wang MW Mayo AS Baldwin Jr 1996 TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB Science 274 784 787 1:CAS:528:DyaK28XmsFOhu7Y%3D 10.1126/science.274.5288.784
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
38
-
-
70449669190
-
Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action
-
10.1186/1476-4598-8-81
-
S Wang Q Liu Y Zhang K Liu P Yu K Liu J Luan H Duan Z Lu F Wang E Wu K Yagasaki G Zhang 2009 Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action Mol Cancer 8 81 10.1186/1476-4598-8-81
-
(2009)
Mol Cancer
, vol.8
, pp. 81
-
-
Wang, S.1
Liu, Q.2
Zhang, Y.3
Liu, K.4
Yu, P.5
Liu, K.6
Luan, J.7
Duan, H.8
Lu, Z.9
Wang, F.10
Wu, E.11
Yagasaki, K.12
Zhang, G.13
-
39
-
-
15844376168
-
The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells
-
1:CAS:528:DyaK28Xjs1Oitr4%3D 10.1074/jbc.271.24.14067
-
M Watabe Y Masuda S Nakajo T Yoshida Y Kuroiwa K Nakaya 1996 The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells J Biol Chem 271 14067 14072 1:CAS:528:DyaK28Xjs1Oitr4%3D 10.1074/jbc.271.24.14067
-
(1996)
J Biol Chem
, vol.271
, pp. 14067-14072
-
-
Watabe, M.1
Masuda, Y.2
Nakajo, S.3
Yoshida, T.4
Kuroiwa, Y.5
Nakaya, K.6
-
40
-
-
0036968347
-
Activation of the PI3 K/Akt pathway and chemotherapeutic resistance
-
1:CAS:528:DC%2BD3sXhtlShtbg%3D 10.1016/S1368-7646(02)00120-6
-
KA West SS Castillo PA Dennis 2002 Activation of the PI3 K/Akt pathway and chemotherapeutic resistance Drug Resist Updat 5 234 248 1:CAS:528: DC%2BD3sXhtlShtbg%3D 10.1016/S1368-7646(02)00120-6
-
(2002)
Drug Resist Updat
, vol.5
, pp. 234-248
-
-
West, K.A.1
Castillo, S.S.2
Dennis, P.A.3
-
41
-
-
16544369324
-
Effect of the water-soluble and non-dialyzable fraction isolated from senso (Chan Su) on lymphocyte proliferation and natural killer activity in C3H mice
-
10.1248/bpb.27.256
-
S Yasuharu I Eiji I Chihiro 2004 Effect of the water-soluble and non-dialyzable fraction isolated from senso (Chan Su) on lymphocyte proliferation and natural killer activity in C3H mice Biol Pharm Bull 27 256 260 10.1248/bpb.27.256
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 256-260
-
-
Yasuharu, S.1
Eiji, I.2
Chihiro, I.3
-
42
-
-
57349105671
-
Apoptotic signaling in bufalin- and cinobufagin-treated androgen-dependent and -independent human prostate cancer cells
-
1:CAS:528:DC%2BD1MXisF2ntA%3D%3D 10.1111/j.1349-7006.2008.00966.x
-
CH Yu SF Kan HF Pu E Jea Chien PS Wang 2008 Apoptotic signaling in bufalin- and cinobufagin-treated androgen-dependent and -independent human prostate cancer cells Cancer Sci 99 2467 2476 1:CAS:528:DC%2BD1MXisF2ntA%3D%3D 10.1111/j.1349-7006.2008.00966.x
-
(2008)
Cancer Sci
, vol.99
, pp. 2467-2476
-
-
Yu, C.H.1
Kan, S.F.2
Pu, H.F.3
Jea Chien, E.4
Wang, P.S.5
-
43
-
-
70449534614
-
Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling
-
1:CAS:528:DC%2BD1MXhtlCjsLjJ 10.1007/s10616-009-9225-9
-
P Yu Q Liu K Liu K Yagasaki E Wu G Zhang 2009 Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling Cytotechnology 59 219 229 1:CAS:528:DC%2BD1MXhtlCjsLjJ 10.1007/s10616-009-9225-9
-
(2009)
Cytotechnology
, vol.59
, pp. 219-229
-
-
Yu, P.1
Liu, Q.2
Liu, K.3
Yagasaki, K.4
Wu, E.5
Zhang, G.6
-
44
-
-
0034434393
-
Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas
-
1:CAS:528:DC%2BD3MXmsF2hsLo%3D 10.1207/S15327914NC382-16
-
G Zhang Y Miura K Yagasaki 2000 Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas Nutr Cancer 38 265 273 1:CAS:528:DC%2BD3MXmsF2hsLo%3D 10.1207/S15327914NC382-16
-
(2000)
Nutr Cancer
, vol.38
, pp. 265-273
-
-
Zhang, G.1
Miura, Y.2
Yagasaki, K.3
-
45
-
-
70449533764
-
Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration
-
1:CAS:528:DC%2BD1MXhtlCjsLjE 10.1007/s10616-009-9211-2
-
Y Zhang H Zhang P Yu Q Liu K Liu H Duan G Luan K Yagasaki G Zhang 2009 Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration Cytotechnology 59 191 200 1:CAS:528:DC%2BD1MXhtlCjsLjE 10.1007/s10616-009-9211-2
-
(2009)
Cytotechnology
, vol.59
, pp. 191-200
-
-
Zhang, Y.1
Zhang, H.2
Yu, P.3
Liu, Q.4
Liu, K.5
Duan, H.6
Luan, G.7
Yagasaki, K.8
Zhang, G.9
-
46
-
-
0035736487
-
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
-
1:CAS:528:DC%2BD3MXosVeqsLo%3D 10.1038/ncb1101-973
-
BP Zhou Y Liao W Xia Y Zou B Spohn MC Hung 2001 HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation Nat Cell Biol 3 973 982 1:CAS:528:DC%2BD3MXosVeqsLo%3D 10.1038/ncb1101-973
-
(2001)
Nat Cell Biol
, vol.3
, pp. 973-982
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Zou, Y.4
Spohn, B.5
Hung, M.C.6
|