-
1
-
-
4243333514
-
A rescue factor abolishing neuronal cell death by a wide spectrum of familial alzheimer's disease genes and abeta
-
Hashimoto, Y., Niikura, T., Tajima, H., Yasukawa, T., Sudo, H., Ito, Y., Kita, Y., Kawasumi, M., Kouyama, K., Doyu, M., Sobue, G., Koide, T., Tsuji, S., Lang, J., Kurokawa, K., and Nishimoto, I. (2001) A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta. Proc. Natl. Acad. Sci. U. S. A. 98, 6336-6341
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 6336-6341
-
-
Hashimoto, Y.1
Niikura, T.2
Tajima, H.3
Yasukawa, T.4
Sudo, H.5
Ito, Y.6
Kita, Y.7
Kawasumi, M.8
Kouyama, K.9
Doyu, M.10
Sobue, G.11
Koide, T.12
Tsuji, S.13
Lang, J.14
Kurokawa, K.15
Nishimoto, I.16
-
2
-
-
80052234401
-
Investigating endogenous peptides and peptidases using peptidomics
-
Tinoco, A. D., and Saghatelian, A. (2011) Investigating endogenous peptides and peptidases using peptidomics. Biochemistry 50, 7447-7461
-
(2011)
Biochemistry
, vol.50
, pp. 7447-7461
-
-
Tinoco, A.D.1
Saghatelian, A.2
-
3
-
-
0036903298
-
Mitochondrial 16s rrna gene encodes a functional peptide, a potential drug for alzheimer's disease and target for cancer therapy
-
Maximov, V., Martynenko, A., Hunsmann, G., and Tarantul, V. (2002) Mitochondrial 16S rRNA gene encodes a functional peptide, a potential drug for Alzheimer's disease and target for cancer therapy. Med. Hypotheses 59, 670-673
-
(2002)
Med. Hypotheses
, vol.59
, pp. 670-673
-
-
Maximov, V.1
Martynenko, A.2
Hunsmann, G.3
Tarantul, V.4
-
4
-
-
0013056674
-
Identification of essential amino acids in humanin, a neuroprotective factor against alzheimer's disease-relevant insults
-
Yamagishi, Y., Hashimoto, Y., Niikura, T., and Nishimoto, I. (2003) Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults. Peptides 24, 585-595
-
(2003)
Peptides
, vol.24
, pp. 585-595
-
-
Yamagishi, Y.1
Hashimoto, Y.2
Niikura, T.3
Nishimoto, I.4
-
5
-
-
0035864169
-
Amyloid (beta)42 activates a g-protein-coupled chemoattractant receptor, fpr-like-1
-
Le, Y., Gong, W., Tiffany, H. L., Tumanov, A., Nedospasov, S., Shen, W., Dunlop, N. M., Gao, J. L., Murphy, P. M., Oppenheim, J. J., and Wang, J. M. (2001) Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1. J. Neurosci. 21, RC123
-
(2001)
J. Neurosci.
, vol.21
-
-
Le, Y.1
Gong, W.2
Tiffany, H.L.3
Tumanov, A.4
Nedospasov, S.5
Shen, W.6
Dunlop, N.M.7
Gao, J.L.8
Murphy, P.M.9
Oppenheim, J.J.10
Wang, J.M.11
-
6
-
-
4744351478
-
N-formylated humanin activates both formyl peptide receptor-like 1 and 2
-
Harada, M., Habata, Y., Hosoya, M., Nishi, K., Fujii, R., Kobayashi, M., and Hinuma, S. (2004) N-Formylated humanin activates both formyl peptide receptor-like 1 and 2. Biochem. Biophys. Res. Commun. 324, 255-261
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.324
, pp. 255-261
-
-
Harada, M.1
Habata, Y.2
Hosoya, M.3
Nishi, K.4
Fujii, R.5
Kobayashi, M.6
Hinuma, S.7
-
7
-
-
67449124590
-
Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving cntf receptor alpha/wsx-1/gp130
-
Hashimoto, Y., Kurita, M., Aiso, S., Nishimoto, I., and Matsuoka, M. (2009) Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130. Mol. Biol. Cell 20, 2864-2873
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 2864-2873
-
-
Hashimoto, Y.1
Kurita, M.2
Aiso, S.3
Nishimoto, I.4
Matsuoka, M.5
-
8
-
-
0242268394
-
Interaction between the alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis
-
Ikonen, M., Liu, B., Hashimoto, Y., Ma, L., Lee, K. W., Niikura, T., Nishimoto, I., and Cohen, P. (2003) Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis. Proc. Natl. Acad. Sci. U. S. A. 100, 13042-13047
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 13042-13047
-
-
Ikonen, M.1
Liu, B.2
Hashimoto, Y.3
Ma, L.4
Lee, K.W.5
Niikura, T.6
Nishimoto, I.7
Cohen, P.8
-
9
-
-
26444463390
-
Involvement of tyrosine kinases and stat3 in humanin-mediated neuroprotection
-
Hashimoto, Y., Suzuki, H., Aiso, S., Niikura, T., Nishimoto, I., and Matsuoka, M. (2005) Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection. Life Sci. 77, 3092-3104
-
(2005)
Life Sci.
, vol.77
, pp. 3092-3104
-
-
Hashimoto, Y.1
Suzuki, H.2
Aiso, S.3
Niikura, T.4
Nishimoto, I.5
Matsuoka, M.6
-
10
-
-
20244361899
-
Involvement of c-jun n-terminal kinase in amyloid precursor protein-mediated neuronal cell death
-
Hashimoto, Y., Tsuji, O., Niikura, T., Yamagishi, Y., Ishizaka, M., Kawasumi, M., Chiba, T., Kanekura, K., Yamada, M., Tsukamoto, E., Kouyama, K., Terashita, K., Aiso, S., Lin, A., and Nishimoto, I. (2003) Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death. J. Neurochem. 84, 864-877
-
(2003)
J. Neurochem.
, vol.84
, pp. 864-877
-
-
Hashimoto, Y.1
Tsuji, O.2
Niikura, T.3
Yamagishi, Y.4
Ishizaka, M.5
Kawasumi, M.6
Chiba, T.7
Kanekura, K.8
Yamada, M.9
Tsukamoto, E.10
Kouyama, K.11
Terashita, K.12
Aiso, S.13
Lin, A.14
Nishimoto, I.15
-
11
-
-
33646544332
-
Neuronal cell death in alzheimer's disease and a neuroprotective factor, humanin
-
Niikura, T., Tajima, H., and Kita, Y. (2006) Neuronal cell death in Alzheimer's disease and a neuroprotective factor, humanin. Curr. Neuropharmacol. 4, 139-147
-
(2006)
Curr. Neuropharmacol.
, vol.4
, pp. 139-147
-
-
Niikura, T.1
Tajima, H.2
Kita, Y.3
-
12
-
-
67749140106
-
Humanin: A novel central regulator of peripheral insulin action
-
Muzumdar, R. H., Huffman, D. M., Atzmon, G., Buettner, C., Cobb, L. J., Fishman, S., Budagov, T., Cui, L., Einstein, F. H., Poduval, A., Hwang, D., Barzilai, N., and Cohen, P. (2009) Humanin: a novel central regulator of peripheral insulin action. PLoS One 4, e6334
-
(2009)
PLoS One
, vol.4
-
-
Muzumdar, R.H.1
Huffman, D.M.2
Atzmon, G.3
Buettner, C.4
Cobb, L.J.5
Fishman, S.6
Budagov, T.7
Cui, L.8
Einstein, F.H.9
Poduval, A.10
Hwang, D.11
Barzilai, N.12
Cohen, P.13
-
13
-
-
0037166058
-
Evidence for in vivo production of humanin peptide, a neuroprotective factor against alzheimer's disease-related insults
-
Tajima, H., Niikura, T., Hashimoto, Y., Ito, Y., Kita, Y., Terashita, K., Yamazaki, K., Koto, A., Aiso, S., and Nishimoto, I. (2002) Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults. Neurosci. Lett. 324, 227-231
-
(2002)
Neurosci. Lett.
, vol.324
, pp. 227-231
-
-
Tajima, H.1
Niikura, T.2
Hashimoto, Y.3
Ito, Y.4
Kita, Y.5
Terashita, K.6
Yamazaki, K.7
Koto, A.8
Aiso, S.9
Nishimoto, I.10
-
14
-
-
77957714219
-
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
-
Muzumdar, R. H., Huffman, D. M., Calvert, J. W., Jha, S., Weinberg, Y., Cui, L., Nemkal, A., Atzmon, G., Klein, L., Gundewar, S., Ji, S. Y., Lavu, M., Predmore, B. L., and Lefer, D. J. (2010) Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice. Arterioscler. Thromb. Vasc. Biol. 30, 1940-1948
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 1940-1948
-
-
Muzumdar, R.H.1
Huffman, D.M.2
Calvert, J.W.3
Jha, S.4
Weinberg, Y.5
Cui, L.6
Nemkal, A.7
Atzmon, G.8
Klein, L.9
Gundewar, S.10
Ji, S.Y.11
Lavu, M.12
Predmore, B.L.13
Lefer, D.J.14
-
15
-
-
0037262465
-
Humanin rescues human cerebrovascular smooth muscle cells from abeta-induced toxicity
-
Jung, S. S., and Van Nostrand, W. E. (2003) Humanin rescues human cerebrovascular smooth muscle cells from Abeta-induced toxicity. J. Neurochem. 84, 266-272
-
(2003)
J. Neurochem.
, vol.84
, pp. 266-272
-
-
Jung, S.S.1
Nostrand, V.W.2
-
16
-
-
12444261796
-
Two serine residues distinctly regulate the rescue function of humanin, an inhibiting factor of alzheimer's disease-related neurotoxicity: Functional potentiation by isomerization and dimerization
-
Terashita, K., Hashimoto, Y., Niikura, T., Tajima, H., Yamagishi, Y., Ishizaka, M., Kawasumi, M., Chiba, T., Kanekura, K., Yamada, M., Nawa, M., Kita, Y., Aiso, S., and Nishimoto, I. (2003) Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: functional potentiation by isomerization and dimerization. J. Neurochem. 85, 1521-1538
-
(2003)
J. Neurochem.
, vol.85
, pp. 1521-1538
-
-
Terashita, K.1
Hashimoto, Y.2
Niikura, T.3
Tajima, H.4
Yamagishi, Y.5
Ishizaka, M.6
Kawasumi, M.7
Chiba, T.8
Kanekura, K.9
Yamada, M.10
Nawa, M.11
Kita, Y.12
Aiso, S.13
Nishimoto, I.14
-
17
-
-
84055189716
-
Advances in characterization of neuroprotective peptide, humanin
-
Arakawa, T., Hirano, A., Shiraki, K., Niikura, T., and Kita, Y. (2011) Advances in characterization of neuroprotective peptide, humanin. Curr. Med. Chem. 18, 5554-5563
-
(2011)
Curr. Med. Chem.
, Issue.18
, pp. 5554-5563
-
-
Arakawa, T.1
Hirano, A.2
Shiraki, K.3
Niikura, T.4
Kita, Y.5
-
18
-
-
2942594839
-
Humanin antagonists: Mutants that interfere with dimerization inhibit neuroprotection by humanin
-
Hashimoto, Y., Terashita, K., Niikura, T., Yamagishi, Y., Ishizaka, M., Kanekura, K., Chiba, T., Yamada, M., Kita, Y., Aiso, S., Matsuoka, M., and Nishimoto, I. (2004) Humanin antagonists: mutants that interfere with dimerization inhibit neuroprotection by Humanin. Eur. J. Neurosci. 19, 2356-2364
-
(2004)
Eur. J. Neurosci.
, vol.19
, pp. 2356-2364
-
-
Hashimoto, Y.1
Terashita, K.2
Niikura, T.3
Yamagishi, Y.4
Ishizaka, M.5
Kanekura, K.6
Chiba, T.7
Yamada, M.8
Kita, Y.9
Aiso, S.10
Matsuoka, M.11
Nishimoto, I.12
-
19
-
-
33749020532
-
Humanin is a novel neuroprotective agent against stroke
-
Xu, X., Chua, C. C., Gao, J., Hamdy, R. C., and Chua, B. H. (2006) Humanin is a novel neuroprotective agent against stroke. Stroke 37, 2613-2619
-
(2006)
Stroke
, vol.37
, pp. 2613-2619
-
-
Xu, X.1
Chua, C.C.2
Gao, J.3
Hamdy, R.C.4
Chua, B.H.5
-
20
-
-
33750072017
-
The secondary structure analysis of a potent ser14gly analog of antialzheimer peptide, humanin, by circular dichroism
-
Arakawa, T., Niikura, T., Tajima, H., and Kita, Y. (2006) The secondary structure analysis of a potent Ser14Gly analog of antiAlzheimer peptide, Humanin, by circular dichroism. J. Pept. Sci. 12, 639-642
-
(2006)
J. Pept. Sci.
, vol.12
, pp. 639-642
-
-
Arakawa, T.1
Niikura, T.2
Tajima, H.3
Kita, Y.4
-
21
-
-
20144387217
-
A humanin derivative, s14g-hn, prevents amyloid-beta-induced memory impairment in mice
-
Tajima, H., Kawasumi, M., Chiba, T., Yamada, M., Yamashita, K., Nawa, M., Kita, Y., Kouyama, K., Aiso, S., Matsuoka, M., Niikura, T., and Nishimoto, I. (2005) A humanin derivative, S14G-HN, prevents amyloid-beta-induced memory impairment in mice. J. Neurosci. Res. 79, 714-723
-
(2005)
J. Neurosci. Res.
, vol.79
, pp. 714-723
-
-
Tajima, H.1
Kawasumi, M.2
Chiba, T.3
Yamada, M.4
Yamashita, K.5
Nawa, M.6
Kita, Y.7
Kouyama, K.8
Aiso, S.9
Matsuoka, M.10
Niikura, T.11
Nishimoto, I.12
-
22
-
-
1242316262
-
Humanin rescues cortical neurons from prion-peptide-induced apoptosis
-
Sponne, I., Fifre, A., Koziel, V., Kriem, B., Oster, T., and Pillot, T. (2004) Humanin rescues cortical neurons from prion-peptide-induced apoptosis. Mol. Cell. Neurosci. 25, 95-102
-
(2004)
Mol. Cell. Neurosci.
, vol.25
, pp. 95-102
-
-
Sponne, I.1
Fifre, A.2
Koziel, V.3
Kriem, B.4
Oster, T.5
Pillot, T.6
-
23
-
-
0035678839
-
[Gly(14)]-Humanin improved the learning and memory impairment induced by scopolamine in vivo
-
Mamiya, T., and Ukai, M. (2001) [Gly(14)]-Humanin improved the learning and memory impairment induced by scopolamine in vivo. Br. J. Pharmacol. 134, 1597-1599
-
(2001)
Br. J. Pharmacol.
, vol.134
, pp. 1597-1599
-
-
Mamiya, T.1
Ukai, M.2
-
24
-
-
76249131322
-
The neurosurvival factor humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice
-
Hoang, P. T., Park, P., Cobb, L. J., Paharkova-Vatchkova, V., Hakimi, M., Cohen, P., and Lee, K. W. (2010) The neurosurvival factor Humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice. Metabolism 59, 343-349
-
(2010)
Metabolism
, vol.59
, pp. 343-349
-
-
Hoang, P.T.1
Park, P.2
Cobb, L.J.3
Paharkova-Vatchkova, V.4
Hakimi, M.5
Cohen, P.6
Lee, K.W.7
-
25
-
-
2942702172
-
Pancreatic islets isolation using different protocols with in situ flushing and intraductal collagenase injection
-
Kinasiewicz, A., Juszczak, M., Pachecka, J., and Fiedor, P. (2004) Pancreatic islets isolation using different protocols with in situ flushing and intraductal collagenase injection. Physiol. Res. 53, 327-333
-
(2004)
Physiol. Res.
, vol.53
, pp. 327-333
-
-
Kinasiewicz, A.1
Juszczak, M.2
Pachecka, J.3
Fiedor, P.4
-
26
-
-
0023257123
-
Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic b cells predominantly via a regulated, rather than a constitutive, pathway
-
Rhodes, C. J., and Halban, P. A. (1987) Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway. J. Cell Biol. 105, 145-153
-
(1987)
J. Cell Biol.
, vol.105
, pp. 145-153
-
-
Rhodes, C.J.1
Halban, P.A.2
-
27
-
-
0023154010
-
Factors underlying significant underestimations of glucokinase activity in crude liver extracts: Physiological implications of higher cellular activity
-
Davidson, A. L., and Arion, W. J. (1987) Factors underlying significant underestimations of glucokinase activity in crude liver extracts: physiological implications of higher cellular activity. Arch. Biochem. Biophys. 253, 156-167
-
(1987)
Arch. Biochem. Biophys.
, vol.253
, pp. 156-167
-
-
Davidson, A.L.1
Arion, W.J.2
-
28
-
-
0242298595
-
Herpes simplex virus triggers activation of calcium-signaling pathways
-
Cheshenko, N., Del Rosario, B., Woda, C., Marcellino, D., Satlin, L. M., and Herold, B. C. (2003) Herpes simplex virus triggers activation of calcium-signaling pathways. J. Cell Biol. 163, 283-293
-
(2003)
J. Cell Biol.
, Issue.163
, pp. 283-293
-
-
Cheshenko, N.1
Del Rosario, B.2
Woda, C.3
Marcellino, D.4
Satlin, L.M.5
Herold, B.C.6
-
29
-
-
0036868797
-
Glucose-stimulated signaling pathways in biphasic insulin secretion
-
Straub, S. G., and Sharp, G. W. (2002) Glucose-stimulated signaling pathways in biphasic insulin secretion. Diabetes/Metabol Res. Rev. 18, 451-463
-
(2002)
Diabetes/Metabol Res. Rev.
, vol.18
, pp. 451-463
-
-
Straub, S.G.1
Sharp, G.W.2
-
30
-
-
0036318364
-
Signals and pools underlying biphasic insulin secretion
-
Henquin, J. C., Ishiyama, N., Nenquin, M., Ravier, M. A., and Jonas, J. C. (2002) Signals and pools underlying biphasic insulin secretion. Diabetes 51(Suppl. 1), S60-S67
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 1
-
-
Henquin, J.C.1
Ishiyama, N.2
Nenquin, M.3
Ravier, M.A.4
Jonas, J.C.5
-
31
-
-
0000181874
-
Beta-cell lines derived from transgenic mice expressing a hybrid insulin geneoncogene
-
Efrat, S., Linde, S., Kofod, H., Spector, D., Delannoy, M., Grant, S., Hanahan, D., and Baekkeskov, S. (1988) Beta-cell lines derived from transgenic mice expressing a hybrid insulin geneoncogene. Proc. Nat. Acad. Sci. 85, 9037-9041
-
(1988)
Proc. Nat. Acad. Sci.
, vol.85
, pp. 9037-9041
-
-
Efrat, S.1
Linde, S.2
Kofod, H.3
Spector, D.4
Delannoy, M.5
Grant, S.6
Hanahan, D.7
Baekkeskov, S.8
-
32
-
-
0031659962
-
Functional analysis of a conditionally transformed pancreatic beta-cell line
-
Fleischer, N., Chen, C., Surana, M., Leiser, M., Rossetti, L., Pralong, W., and Efrat, S. (1998) Functional analysis of a conditionally transformed pancreatic beta-cell line. Diabetes 47, 1419-1425
-
(1998)
Diabetes
, vol.47
, pp. 1419-1425
-
-
Fleischer, N.1
Chen, C.2
Surana, M.3
Leiser, M.4
Rossetti, L.5
Pralong, W.6
Efrat, S.7
-
33
-
-
57349097780
-
Metabolic cycling in control of glucose-stimulated insulin secretion
-
Jensen, M. V., Joseph, J. W., Ronnebaum, S. M., Burgess, S. C., Sherry, A. D., and Newgard, C. B. (2008) Metabolic cycling in control of glucose-stimulated insulin secretion. Am. J. Physiol. Endocrinol. Metab. 295, E1287-1297
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
-
-
Jensen, M.V.1
Joseph, J.W.2
Ronnebaum, S.M.3
Burgess, S.C.4
Sherry, A.D.5
Newgard, C.B.6
-
34
-
-
0029932643
-
New insights into pancreatic beta-cell metabolic signaling in insulin secretion
-
Prentki, M. (1996) New insights into pancreatic beta-cell metabolic signaling in insulin secretion. Eur. J. Endocrinol. 134, 272-286
-
(1996)
Eur. J. Endocrinol.
, vol.134
, pp. 272-286
-
-
Prentki, M.1
-
35
-
-
0033548138
-
Role of nadh shuttle system in glucoseinduced activation of mitochondrial metabolism and insulin secretion
-
Eto, K., Tsubamoto, Y., Terauchi, Y., Sugiyama, T., Kishimoto, T., Takahashi, N., Yamauchi, N., Kubota, N., Murayama, S., Aizawa, T., Akanuma, Y., Aizawa, S., Kasai, H., Yazaki, Y., and Kadowaki, T. (1999) Role of NADH shuttle system in glucoseinduced activation of mitochondrial metabolism and insulin secretion. Science 283, 981-985
-
(1999)
Science
, vol.283
, pp. 981-985
-
-
Eto, K.1
Tsubamoto, Y.2
Terauchi, Y.3
Sugiyama, T.4
Kishimoto, T.5
Takahashi, N.6
Yamauchi, N.7
Kubota, N.8
Murayama, S.9
Aizawa, T.10
Akanuma, Y.11
Aizawa, S.12
Kasai, H.13
Yazaki, Y.14
Kadowaki, T.15
-
36
-
-
0037269897
-
Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets
-
Cunningham, B. A., Richard, A. M., Dillon, J. S., Daley, J. T., Civelek, V. N., Deeney, J. T., Yaney, G. C., Corkey, B. E., and Tornheim, K. (2003) Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets. Biochem. J. 369, 173-178
-
(2003)
Biochem. J.
, vol.369
, pp. 173-178
-
-
Cunningham, B.A.1
Richard, A.M.2
Dillon, J.S.3
Daley, J.T.4
Civelek, V.N.5
Deeney, J.T.6
Yaney, G.C.7
Corkey, B.E.8
Tornheim, K.9
-
37
-
-
78149470681
-
Novel gpr119 agonist as1535907 contributes to first-phase insulin secretion in rat perfused pancreas and diabetic db/db mice
-
Yoshida, S., Ohishi, T., Matsui, T., Tanaka, H., Oshima, H., Yonetoku, Y., and Shibasaki, M. (2010) Novel GPR119 agonist AS1535907 contributes to first-phase insulin secretion in rat perfused pancreas and diabetic db/db mice. Biochem. Biophys. Res. Commun. 402, 280-285
-
(2010)
Biochem. Biophys. Res. Commun.
, Issue.402
, pp. 280-285
-
-
Yoshida, S.1
Ohishi, T.2
Matsui, T.3
Tanaka, H.4
Oshima, H.5
Yonetoku, Y.6
Shibasaki, M.7
-
38
-
-
0030067124
-
Banting lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm
-
Matschinsky, F. M. (1996) Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. Diabetes 45, 223-241
-
(1996)
Diabetes
, vol.45
, pp. 223-241
-
-
Matschinsky, F.M.1
-
39
-
-
84862271583
-
Pancreatic function, type 2 diabetes, and metabolism in aging
-
Gong, Z., and Muzumdar, R. H. (2012) Pancreatic function, type 2 diabetes, and metabolism in aging. Int. J. Endocrinol. 2012, 320482
-
(2012)
Int. J. Endocrinol.
, vol.2012
, pp. 320482
-
-
Gong, Z.1
Muzumdar, R.H.2
-
40
-
-
83455197122
-
Glucokinase activation repairs defective bioenergetics of islets of langerhans isolated from type 2 diabetics
-
Doliba, N. M., Qin, W., Najafi, H., Liu, C., Buettger, C. W., Sotiris, J., Collins, H. W., Li, C., Stanley, C. A., Wilson, D. F., Grimsby, J., Sarabu, R., Naji, A., and Matschinsky, F. M. (2012) Glucokinase activation repairs defective bioenergetics of islets of Langerhans isolated from type 2 diabetics. Am. J. Physiol. Endocrinol. Metab. 302, E87-E102
-
(2012)
Am. J. Physiol. Endocrinol. Metab.
, vol.302
-
-
Doliba, N.M.1
Qin, W.2
Najafi, H.3
Liu, C.4
Buettger, C.W.5
Sotiris, J.6
Collins, H.W.7
Li, C.8
Stanley, C.A.9
Wilson, D.F.10
Grimsby, J.11
Sarabu, R.12
Naji, A.13
Matschinsky, F.M.14
-
41
-
-
0026608764
-
Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulindependent diabetes mellitus
-
Froguel, P., Vaxillaire, M., Sun, F., Velho, G., Zouali, H., Butel, M. O., Lesage, S., Vionnet, N., Clement, K., Fougerousse, F., Tanizawa, Y., Weissenbach, J., Beckmann, J. S., Lathrop, G. M., Passa, P., Permutt, M. A., and Cohen, D. (1992) Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulindependent diabetes mellitus. Nature 356, 162-164
-
(1992)
Nature
, vol.356
, pp. 162-164
-
-
Froguel, P.1
Vaxillaire, M.2
Sun, F.3
Velho, G.4
Zouali, H.5
Butel, M.O.6
Lesage, S.7
Vionnet, N.8
Clement, K.9
Fougerousse, F.10
Tanizawa, Y.11
Weissenbach, J.12
Beckmann, J.S.13
Lathrop, G.M.14
Passa, P.15
Permutt, M.A.16
Cohen, D.17
-
42
-
-
0026562918
-
Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus
-
Vionnet, N., Stoffel, M., Takeda, J., Yasuda, K., Bell, G. I., Zouali, H., Lesage, S., Velho, G., Iris, F., Passa, P., Froguel, P., and Cohen, D. (1992) Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus. Nature 356, 721-722
-
(1992)
Nature
, vol.356
, pp. 721-722
-
-
Vionnet, N.1
Stoffel, M.2
Takeda, J.3
Yasuda, K.4
Bell, G.I.5
Zouali, H.6
Lesage, S.7
Velho, G.8
Iris, F.9
Passa, P.10
Froguel, P.11
Cohen, D.12
-
43
-
-
0029417331
-
Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose
-
Terauchi, Y., Sakura, H., Yasuda, K., Iwamoto, K., Takahashi, N., Ito, K., Kasai, H., Suzuki, H., Ueda, O., Kamada, N., Jishage, K., Komeda, K., Noda, M., Kanazawa, Y., Taniguchi, S., Miwa, I., Akanuma, Y., Kodama, T., Yazaki, Y., and Kadowaki, T. (1995) Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose. J. Biol. Chem. 270, 30253-30256
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 30253-30256
-
-
Terauchi, Y.1
Sakura, H.2
Yasuda, K.3
Iwamoto, K.4
Takahashi, N.5
Ito, K.6
Kasai, H.7
Suzuki, H.8
Ueda, O.9
Kamada, N.10
Jishage, K.11
Komeda, K.12
Noda, M.13
Kanazawa, Y.14
Taniguchi, S.15
Miwa, I.16
Akanuma, Y.17
Kodama, T.18
Yazaki, Y.19
Kadowaki, T.20
more..
-
44
-
-
84860567700
-
Fuel-stimulated insulin secretion depends upon mitochondria activation and the integration of mitochondrial and cytosolic substrate cycles
-
Cline, G. W. (2011) Fuel-stimulated insulin secretion depends upon mitochondria activation and the integration of mitochondrial and cytosolic substrate cycles. Diabetes Metab. J. 35, 458-465
-
(2011)
Diabetes Metab. J.
, Issue.35
, pp. 458-465
-
-
Cline, G.W.1
-
45
-
-
0033520294
-
Nadh shuttle system regulates k(atp) channel-dependent pathway and steps distal to cytosolic ca(2+) concentration elevation in glucose-induced insulin secretion
-
Eto, K., Suga, S., Wakui, M., Tsubamoto, Y., Terauchi, Y., Taka, J., Aizawa, S., Noda, M., Kimura, S., Kasai, H., and Kadowaki, T. (1999) NADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretion. J. Biol. Chem. 274, 25386-25392
-
(1999)
J. Biol. Chem.
, Issue.274
, pp. 25386-25392
-
-
Eto, K.1
Suga, S.2
Wakui, M.3
Tsubamoto, Y.4
Terauchi, Y.5
Taka, J.6
Aizawa, S.7
Noda, M.8
Kimura, S.9
Kasai, H.10
Kadowaki, T.11
-
46
-
-
9544249496
-
Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from min6 and hit cells
-
Ishihara, H., Nakazaki, M., Kanegae, Y., Inukai, K., Asano, T., Katagiri, H., Yazaki, Y., Kikuchi, M., Miyazaki, J., Saito, I., and Oka, Y. (1996) Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from MIN6 and HIT cells. Diabetes 45, 1238-1244
-
(1996)
Diabetes
, vol.45
, pp. 1238-1244
-
-
Ishihara, H.1
Nakazaki, M.2
Kanegae, Y.3
Inukai, K.4
Asano, T.5
Katagiri, H.6
Yazaki, Y.7
Kikuchi, M.8
Miyazaki, J.9
Saito, I.10
Oka, Y.11
-
47
-
-
0034544579
-
Mouse lacking nad-linked glycerol phosphate dehydrogenase has normal pancreatic beta cell function but abnormal metabolite pattern in skeletal muscle
-
MacDonald, M. J., and Marshall, L. K. (2000) Mouse lacking NAD-linked glycerol phosphate dehydrogenase has normal pancreatic beta cell function but abnormal metabolite pattern in skeletal muscle. Arch. Biochem. Biophys. 384, 143-153
-
(2000)
Arch. Biochem. Biophys.
, vol.384
, pp. 143-153
-
-
MacDonald, M.J.1
Marshall, L.K.2
-
48
-
-
0041858096
-
Systems biology: Understanding cells
-
Nurse, P. (2003) Systems biology: understanding cells. Nature 424, 883
-
(2003)
Nature
, vol.424
, pp. 883
-
-
Nurse, P.1
-
49
-
-
79952674000
-
Interactome networks and human disease
-
Vidal, M., Cusick, M. E., and Barabasi, A. L. (2011) Interactome networks and human disease. Cell 144, 986-998
-
(2011)
Cell
, vol.144
, pp. 986-998
-
-
Vidal, M.1
Cusick, M.E.2
Barabasi, A.L.3
-
50
-
-
79955605398
-
Research and development of glucokinase activators for diabetes therapy: Theoretical and practical aspects
-
Matschinsky, F. M., Zelent, B., Doliba, N. M., Kaestner, K. H., Vanderkooi, J. M., Grimsby, J., Berthel, S. J., and Sarabu, R. (2011) Research and development of glucokinase activators for diabetes therapy: theoretical and practical aspects. Handb. Exp. Pharmacol. 203, 357-401
-
(2011)
Handb. Exp. Pharmacol.
, Issue.203
, pp. 357-401
-
-
Matschinsky, F.M.1
Zelent, B.2
Doliba, N.M.3
Kaestner, K.H.4
Vanderkooi, J.M.5
Grimsby, J.6
Berthel, S.J.7
Sarabu, R.8
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