Activation of Rac by Asef2 promotes myosin IIdependent contractility to inhibit cell migration on type I collagen

Journal of Cell Science

Volumn 126, Issue 24, 2013, Pages 5585-5597

  Jean, Leólène ^a   Majumdar, Devi ^a   Shi, Mingjian ^a   Hinkle, Louis E ^a   Diggins, Nicole L ^a   Ao, Mingfang ^a   Broussard, Joshua A ^a   Evans, J Corey ^a   Choma, David P ^a,b   Webb, Donna J ^a,c  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

1 integrin; Actomyosin; Adhesion dynamics; Asef2; Guanine nucleotide exchange factor; Rho GTPases; SPATA13

Indexed keywords

ASEF2 PROTEIN; BETA1 INTEGRIN; BLEBBISTATIN; COLLAGEN TYPE 1; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN II; RAC PROTEIN; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL ADHESION; CELL MATURATION; CONTROLLED STUDY; ENZYME METABOLISM; EXPERIMENTAL RABBIT; GENE ACTIVATION; GENE SILENCING; MIGRATION INHIBITION; MUSCLE CONTRACTILITY; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

ACTOMYOSIN; ADHESION DYNAMICS; ASEF2; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RHO GTPASES; SPATA13; Β1 INTEGRIN;

ANTIGENS, CD29; CDC42 GTP-BINDING PROTEIN; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; COLLAGEN TYPE I; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MYOSIN TYPE II; RAC GTP-BINDING PROTEINS;

EID: 84890523471     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.131060     Document Type: Article

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