Insulin receptor isoform switching in intestinal stem cells, progenitors, differentiated lineages and tumors: Evidence that IR-B limits proliferation

Journal of Cell Science

Volumn 126, Issue 24, 2013, Pages 5645-5656

  Andres, Sarah F ^a   Simmons, James G ^a   Mah, Amanda T ^b   Santoro, M Agostina ^a   Van Landeghem, Laurianne ^a   Lund, P Kay ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b University of North Carolina at Chapel Hill   (United States)

Author keywords

Colon cancer; Differentiation; Insulin receptor isoform B; Intestinal stem cell; Proliferation

Indexed keywords

INSULIN RECEPTOR; INSULIN RECEPTOR A; INSULIN RECEPTOR B; PROTEIN ZO1; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CANCER CELL CULTURE; CARCINOGENICITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN CACO 2; CONTROLLED STUDY; DNA SYNTHESIS; EXON; HUMAN; INTESTINE CELL; INTESTINE EPITHELIUM; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA SPLICING; SIGNAL TRANSDUCTION; STEM CELL;

COLON CANCER; DIFFERENTIATION; INSULIN RECEPTOR ISOFORM B; INTESTINAL STEM CELL; PROLIFERATION;

ANIMALS; BETA CATENIN; CACO-2 CELLS; CELL DIFFERENTIATION; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DNA REPLICATION; GENE EXPRESSION; HUMANS; INTESTINAL MUCOSA; MICE; PHENOTYPE; PROTEIN ISOFORMS; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; STEM CELLS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84890462958     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.132985     Document Type: Article

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