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Volumn 150, Issue 8, 2009, Pages 3611-3619

Insulin-like growth factor type 1 receptor and insulin receptor isoform expression and signaling in mammary epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR A; INSULIN RECEPTOR B; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

EID: 67651174535     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1473     Document Type: Article
Times cited : (36)

References (43)
  • 1
    • 0026746298 scopus 로고
    • Expression of IGF-I and IGF-II mRNA in breast tissue
    • Paik S 1992 Expression of IGF-I and IGF-II mRNA in breast tissue. Breast Cancer Res Treat 22:31-38
    • (1992) Breast Cancer Res Treat , vol.22 , pp. 31-38
    • Paik, S.1
  • 2
    • 0024550730 scopus 로고
    • Analysis of insulin-like growth factor I gene expression in malignancy: Evidence for a paracrine role in human breast cancer
    • Yee D, Paik S, Lebovic GS, Marcus RR, Favoni RE, Cullen KJ, Lippman ME, Rosen N 1989 Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer. Mol Endocrinol 3:509-517
    • (1989) Mol Endocrinol , vol.3 , pp. 509-517
    • Yee, D.1    Paik, S.2    Lebovic, G.S.3    Marcus, R.R.4    Favoni, R.E.5    Cullen, K.J.6    Lippman, M.E.7    Rosen, N.8
  • 3
    • 0032922633 scopus 로고    scopus 로고
    • The insulin-like growth factors (IGF) and IGF type I receptor during postnatal growth of the murine mammary gland: Sites of messenger ribonucleic acid expression and potential functions
    • Richert MM, Wood TL 1999 The insulin-like growth factors (IGF) and IGF type I receptor during postnatal growth of the murine mammary gland: sites of messenger ribonucleic acid expression and potential functions. Endocrinology 140:454-461
    • (1999) Endocrinology , vol.140 , pp. 454-461
    • Richert, M.M.1    Wood, T.L.2
  • 4
    • 0033303817 scopus 로고    scopus 로고
    • Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development
    • Ruan W, Kleinberg DL 1999 Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development. Endocrinology 140:5075-5081
    • (1999) Endocrinology , vol.140 , pp. 5075-5081
    • Ruan, W.1    Kleinberg, D.L.2
  • 5
    • 0033847571 scopus 로고    scopus 로고
    • IGF-I: An essential factor in terminal end bud formation and ductal morphogenesis
    • Kleinberg DL, Feldman M, Ruan W 2000 IGF-I: an essential factor in terminal end bud formation and ductal morphogenesis. J Mammary Gland Biol Neoplasia 5:7-17
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 7-17
    • Kleinberg, D.L.1    Feldman, M.2    Ruan, W.3
  • 6
    • 3042596853 scopus 로고    scopus 로고
    • Mammary gland branching morphogenesis is diminished in mice with a deficiency of insulin-like growth factor-I (IGF-I), but not in mice with a liver-specific deletion of IGF-I
    • Richards RG, Klotz DM, Walker MP, Diaugustine RP 2004 Mammary gland branching morphogenesis is diminished in mice with a deficiency of insulin-like growth factor-I (IGF-I), but not in mice with a liver-specific deletion of IGF-I. Endocrinology 145:3106-3110
    • (2004) Endocrinology , vol.145 , pp. 3106-3110
    • Richards, R.G.1    Klotz, D.M.2    Walker, M.P.3    Diaugustine, R.P.4
  • 13
    • 0030670432 scopus 로고    scopus 로고
    • The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue
    • Happerfield LC, Miles DW, Barnes DM, Thomsen LL, Smith P, Hanby A 1997 The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue. J Pathol 183:412-417
    • (1997) J Pathol , vol.183 , pp. 412-417
    • Happerfield, L.C.1    Miles, D.W.2    Barnes, D.M.3    Thomsen, L.L.4    Smith, P.5    Hanby, A.6
  • 14
    • 0034748607 scopus 로고    scopus 로고
    • Targeted disruption of the IGF-I receptor gene decreases cellular proliferation inmammaryterminal end buds
    • Bonnette SG, Hadsell DL 2001 Targeted disruption of the IGF-I receptor gene decreases cellular proliferation inmammaryterminal end buds. Endocrinology 142:4937-4945
    • (2001) Endocrinology , vol.142 , pp. 4937-4945
    • Bonnette, S.G.1    Hadsell, D.L.2
  • 17
    • 0001519705 scopus 로고    scopus 로고
    • Rescue of mammary epithelium of early lethal phenotypes by embryonic mammary gland transplantation as exemplified with insulin receptor null mice
    • IpMM, Asch BB, eds, New York: Kluwer Academic/Plenum Publishers;
    • Robinson G, Accili D, Hennighausen L 2000 Rescue of mammary epithelium of early lethal phenotypes by embryonic mammary gland transplantation as exemplified with insulin receptor null mice. In: IpMM, Asch BB, eds. Methods in mammary gland biology and breast cancer research. New York: Kluwer Academic/Plenum Publishers; 307-316
    • (2000) Methods in mammary gland biology and breast cancer research , pp. 307-316
    • Robinson, G.1    Accili, D.2    Hennighausen, L.3
  • 18
    • 0037131385 scopus 로고    scopus 로고
    • Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved
    • Pandini G, Frasca F, Mineo R, Sciacca L, Vigneri R, Belfiore A 2002 Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved. J Biol Chem 277: 39684-39695
    • (2002) J Biol Chem , vol.277 , pp. 39684-39695
    • Pandini, G.1    Frasca, F.2    Mineo, R.3    Sciacca, L.4    Vigneri, R.5    Belfiore, A.6
  • 19
    • 34247872895 scopus 로고    scopus 로고
    • Characterization of insulin/IGF hybrid receptors: Contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation
    • Benyoucef S, Surinya KH, Hadaschik D, Siddle K 2007 Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation. Biochem J 403:603-613
    • (2007) Biochem J , vol.403 , pp. 603-613
    • Benyoucef, S.1    Surinya, K.H.2    Hadaschik, D.3    Siddle, K.4
  • 20
    • 0027730575 scopus 로고
    • Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification
    • Kasuya J, Paz IB, Maddux BA, Goldfine ID, Hefta SA, Fujita-Yamaguchi Y 1993 Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification. Biochemistry 32:13531-13536
    • (1993) Biochemistry , vol.32 , pp. 13531-13536
    • Kasuya, J.1    Paz, I.B.2    Maddux, B.A.3    Goldfine, I.D.4    Hefta, S.A.5    Fujita-Yamaguchi, Y.6
  • 21
    • 0030693249 scopus 로고    scopus 로고
    • Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: Quantification of individual receptor species by selective immunoprecipitation and immunoblotting
    • Bailyes EM, Nave BT, Soos MA, Orr SR, Hayward AC, Siddle K 1997 Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting. Biochem J 327(Pt 1):209-215
    • (1997) Biochem J , vol.327 , Issue.PART 1 , pp. 209-215
    • Bailyes, E.M.1    Nave, B.T.2    Soos, M.A.3    Orr, S.R.4    Hayward, A.C.5    Siddle, K.6
  • 22
    • 0027513284 scopus 로고
    • Relationship between α-subunit ligand occupancy and β-subunit autophosphorylation in insulin/insulin-like growth factor-1 hybrid receptors
    • Frattali AL, Pessin JE 1993 Relationship between α-subunit ligand occupancy and β-subunit autophosphorylation in insulin/insulin-like growth factor-1 hybrid receptors. J Biol Chem 268:7393-7400
    • (1993) J Biol Chem , vol.268 , pp. 7393-7400
    • Frattali, A.L.1    Pessin, J.E.2
  • 23
    • 33748744723 scopus 로고    scopus 로고
    • Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant
    • Slaaby R, Schäffer L, Lautrup-Larsen I, Andersen AS, Shaw AC, Mathiasen IS, Brandt J 2006 Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant. J Biol Chem 281:25869-25874
    • (2006) J Biol Chem , vol.281 , pp. 25869-25874
    • Slaaby, R.1    Schäffer, L.2    Lautrup-Larsen, I.3    Andersen, A.S.4    Shaw, A.C.5    Mathiasen, I.S.6    Brandt, J.7
  • 24
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • Jones JI, Clemmons DR 1995 Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 16:3-34
    • (1995) Endocr Rev , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 25
    • 0003078264 scopus 로고    scopus 로고
    • Collagen gel method for the primary culture of mouse mammary epithelium
    • Ip MM, Asch BB, eds, New York: Kluwer Academic/Plenum Publishers;
    • Imagawa W, Yang J, Guzman RC, Nandi S 2000 Collagen gel method for the primary culture of mouse mammary epithelium. In: Ip MM, Asch BB, eds. Methods in mammary gland biology and breast cancer research. New York: Kluwer Academic/Plenum Publishers; 111-123
    • (2000) Methods in mammary gland biology and breast cancer research , pp. 111-123
    • Imagawa, W.1    Yang, J.2    Guzman, R.C.3    Nandi, S.4
  • 26
    • 0031674851 scopus 로고    scopus 로고
    • Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast
    • Stingl J, Eaves CJ, Kuusk U, Emerman JT 1998 Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast. Differentiation 63:201-213
    • (1998) Differentiation , vol.63 , pp. 201-213
    • Stingl, J.1    Eaves, C.J.2    Kuusk, U.3    Emerman, J.T.4
  • 27
    • 0027502045 scopus 로고
    • Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity
    • Soos MA, Field CE, Siddle K 1993 Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity. Biochem J 290(Pt 2):419-426
    • (1993) Biochem J , vol.290 , Issue.PART 2 , pp. 419-426
    • Soos, M.A.1    Field, C.E.2    Siddle, K.3
  • 28
    • 34547880716 scopus 로고    scopus 로고
    • Decreased lactation capacity and altered milk composition in insulin receptor substrate null mice is associated with decreased maternal body mass and reduced insulin-dependent phosphorylation of mammary Akt
    • Hadsell DL, Olea W, Lawrence N, George J, Torres D, Kadowaki T, Lee AV 2007 Decreased lactation capacity and altered milk composition in insulin receptor substrate null mice is associated with decreased maternal body mass and reduced insulin-dependent phosphorylation of mammary Akt. J Endocrinol 194:327-336
    • (2007) J Endocrinol , vol.194 , pp. 327-336
    • Hadsell, D.L.1    Olea, W.2    Lawrence, N.3    George, J.4    Torres, D.5    Kadowaki, T.6    Lee, A.V.7
  • 32
    • 0037508585 scopus 로고    scopus 로고
    • Signaling differences from the A and B isoforms of the insulin receptor (IR) in 32D cells in the presence or absence of IR substrate-1
    • Sciacca L, Prisco M, Wu A, Belfiore A, Vigneri R, Baserga R 2003 Signaling differences from the A and B isoforms of the insulin receptor (IR) in 32D cells in the presence or absence of IR substrate-1. Endocrinology 144:2650-2658
    • (2003) Endocrinology , vol.144 , pp. 2650-2658
    • Sciacca, L.1    Prisco, M.2    Wu, A.3    Belfiore, A.4    Vigneri, R.5    Baserga, R.6
  • 33
    • 0036721496 scopus 로고    scopus 로고
    • Functional insulin receptors on human epithelial ovarian carcinoma cells: Implications for IGF-II mitogenic signaling
    • Kalli KR, Falowo OI, Bale LK, Zschunke MA, Roche PC, Conover CA 2002 Functional insulin receptors on human epithelial ovarian carcinoma cells: implications for IGF-II mitogenic signaling. Endocrinology 143:3259-3267
    • (2002) Endocrinology , vol.143 , pp. 3259-3267
    • Kalli, K.R.1    Falowo, O.I.2    Bale, L.K.3    Zschunke, M.A.4    Roche, P.C.5    Conover, C.A.6
  • 34
    • 0347951408 scopus 로고    scopus 로고
    • The mRNA expression of insulin receptor isoforms (IR-A and IR-B) and IGFR-2 in the bovine corpus luteum during the estrous cycle, pregnancy, and induced luteolysis
    • Neuvians TP, Pfaffl MW, Berisha B, Schams D 2003 The mRNA expression of insulin receptor isoforms (IR-A and IR-B) and IGFR-2 in the bovine corpus luteum during the estrous cycle, pregnancy, and induced luteolysis. Endocrine 22:93-100
    • (2003) Endocrine , vol.22 , pp. 93-100
    • Neuvians, T.P.1    Pfaffl, M.W.2    Berisha, B.3    Schams, D.4
  • 35
    • 0027369490 scopus 로고
    • Effect of dexamethasone on the alternative splicing of the insulin receptor mRNA and insulin action in HepG2 hepatoma cells
    • Kosaki A, Webster NJ 1993 Effect of dexamethasone on the alternative splicing of the insulin receptor mRNA and insulin action in HepG2 hepatoma cells. J Biol Chem 268:21990-21996
    • (1993) J Biol Chem , vol.268 , pp. 21990-21996
    • Kosaki, A.1    Webster, N.J.2
  • 36
    • 33846458639 scopus 로고    scopus 로고
    • Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin
    • Zhang H, Pelzer AM, Kiang DT, Yee D 2007 Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin. Cancer Res 67:391-397
    • (2007) Cancer Res , vol.67 , pp. 391-397
    • Zhang, H.1    Pelzer, A.M.2    Kiang, D.T.3    Yee, D.4
  • 37
    • 0031238774 scopus 로고    scopus 로고
    • Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development
    • Louvi A, Accili D, Efstratiadis A 1997 Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development. Dev Biol 189:33-48
    • (1997) Dev Biol , vol.189 , pp. 33-48
    • Louvi, A.1    Accili, D.2    Efstratiadis, A.3
  • 38
    • 0025362295 scopus 로고
    • Functionally distinct insulin receptors generated by tissue-specific alternative splicing
    • Mosthaf L, Grako K, Dull TJ, Coussens L, Ullrich A, McClain DA 1990 Functionally distinct insulin receptors generated by tissue-specific alternative splicing. EMBO J 9:2409-2413
    • (1990) EMBO J , vol.9 , pp. 2409-2413
    • Mosthaf, L.1    Grako, K.2    Dull, T.J.3    Coussens, L.4    Ullrich, A.5    McClain, D.A.6
  • 40
    • 0041355316 scopus 로고    scopus 로고
    • Bi-directional regulation of brown fat adipogenesis by the insulin receptor
    • Entingh AJ, Taniguchi CM, Kahn CR 2003 Bi-directional regulation of brown fat adipogenesis by the insulin receptor. J Biol Chem 278:33377-33383
    • (2003) J Biol Chem , vol.278 , pp. 33377-33383
    • Entingh, A.J.1    Taniguchi, C.M.2    Kahn, C.R.3
  • 41
    • 57149142057 scopus 로고    scopus 로고
    • IGF and insulin receptor signaling in breast cancer
    • Belfiore A, Frasca F 2008 IGF and insulin receptor signaling in breast cancer. J Mammary Gland Biol Neoplasia 13:381-406
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , pp. 381-406
    • Belfiore, A.1    Frasca, F.2
  • 42
    • 66649113947 scopus 로고    scopus 로고
    • Selective response to insulin versus IGF-I and IGF-II and upregulation of insulin-receptor splice variant B in the differentiated mouse mammary epithelium
    • Berlato C, Doppler W 2009 Selective response to insulin versus IGF-I and IGF-II and upregulation of insulin-receptor splice variant B in the differentiated mouse mammary epithelium. Endocrinology 150:2924-2933
    • (2009) Endocrinology , vol.150 , pp. 2924-2933
    • Berlato, C.1    Doppler, W.2
  • 43
    • 0035719947 scopus 로고    scopus 로고
    • Distinct and overlapping functions of insulin and IGF-I receptors
    • Nakae J, Kido Y, Accili D 2001 Distinct and overlapping functions of insulin and IGF-I receptors. Endocr Rev 22:818-835
    • (2001) Endocr Rev , vol.22 , pp. 818-835
    • Nakae, J.1    Kido, Y.2    Accili, D.3


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