-
1
-
-
68449104156
-
Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: A cohort study
-
Hemkens LG, Grouven U, Bender R, et al. Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study. Diabetologia. 2009;52:1732-1744.
-
(2009)
Diabetologia
, vol.52
, pp. 1732-1744
-
-
Hemkens, L.G.1
Grouven, U.2
Bender, R.3
-
2
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
Currie CJ, Poole CD, Gale EA. The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia. 2009;52:1766-1777.
-
(2009)
Diabetologia
, vol.52
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, C.D.2
Gale, E.A.3
-
3
-
-
68449104625
-
Insulin glargine use and short-term incidence of malignancies-a population-based follow-up study in sweden
-
Jonasson JM, Ljung R, Talbäck M, Haglund B, Gudbjörnsdó ttir S, Steineck G. Insulin glargine use and short-term incidence of malignancies-a population-based follow-up study in Sweden. Diabetologia. 2009;52:1745-1754.
-
(2009)
Diabetologia
, vol.52
, pp. 1745-1754
-
-
Jonasson, J.M.1
Ljung, R.2
Talbäck, M.3
Haglund, B.4
Gudbjörnsdó ttir, S.5
Steineck, G.6
-
4
-
-
68449094354
-
Use of insulin glargine and cancer incidence in Scotland: A study from the scottish diabetes research network epidemiology group
-
SDRN Epidemiology Group
-
Colhoun HM; SDRN Epidemiology Group. Use of insulin glargine and cancer incidence in Scotland: a study from the Scottish Diabetes Research Network Epidemiology Group. Diabetologia. 2009;52:1755-1765.
-
(2009)
Diabetologia
, vol.52
, pp. 1755-1765
-
-
Colhoun, H.M.1
-
5
-
-
2942520997
-
Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults
-
DOI 10.1093/aje/kwh161
-
Coughlin SS, Calle EE, Teras LR, Petrelli J, Thun MJ. Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults. Am J Epidemiol. 2004;159:1160-1167. (Pubitemid 38747263)
-
(2004)
American Journal of Epidemiology
, vol.159
, Issue.12
, pp. 1160-1167
-
-
Coughlin, S.S.1
Calle, E.E.2
Teras, L.R.3
Petrelli, J.4
Thun, M.J.5
-
6
-
-
70349658548
-
A cohort study of the risk of cancer associated with type 2 diabetes
-
Ogunleye AA, Ogston SA, Morris AD, Evans JM. A cohort study of the risk of cancer associated with type 2 diabetes. Br J Cancer. 2009;101:1199-1201.
-
(2009)
Br J Cancer
, vol.101
, pp. 1199-1201
-
-
Ogunleye, A.A.1
Ogston, S.A.2
Morris, A.D.3
Evans, J.M.4
-
7
-
-
38949108241
-
Body-mass index and incidence of cancer: A systematic review and meta-analysis of prospective observational studies
-
DOI 10.1016/S0140-6736(08)60269-X, PII S014067360860269X
-
Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet. 2008;371:569-578. (Pubitemid 351232031)
-
(2008)
The Lancet
, vol.371
, Issue.9612
, pp. 569-578
-
-
Renehan, A.G.1
Tyson, M.2
Egger, M.3
Heller, R.F.4
Zwahlen, M.5
-
8
-
-
79951472326
-
Metformin: Its emerging role in oncology
-
Micic D, Cvijovic G, Trajkovic V, Duntas LH, Polovina S. Metformin: its emerging role in oncology. Hormones (Athens). 2011;10:5-15.
-
(2011)
Hormones (Athens)
, vol.10
, pp. 5-15
-
-
Micic, D.1
Cvijovic, G.2
Trajkovic, V.3
Duntas, L.H.4
Polovina, S.5
-
9
-
-
84869237080
-
Metformin and cancer: New applications for an old drug
-
In press
-
Kourelis TV, Siegel RD. Metformin and cancer: new applications for an old drug. Med Oncol. 2011. In press.
-
(2011)
Med Oncol.
-
-
Kourelis, T.V.1
Siegel, R.D.2
-
10
-
-
33645766204
-
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
-
Bowker SL, Majumdar SR, Veugelers P, Johnson JA. Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin. Diabetes Care. 2006;29:254-258. (Pubitemid 44106500)
-
(2006)
Diabetes Care
, vol.29
, Issue.2
, pp. 254-258
-
-
Bowker, S.L.1
Majumdar, S.R.2
Veugelers, P.3
Johnson, J.A.4
-
11
-
-
77951006620
-
Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma
-
Hassan MM, Curley SA, Li D, et al. Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma. Cancer. 2010;116:1938-1946.
-
(2010)
Cancer
, vol.116
, pp. 1938-1946
-
-
Hassan, M.M.1
Curley, S.A.2
Li, D.3
-
12
-
-
68349148204
-
Insulin glargine and malignancy: An unwarranted alarm
-
Pocock SJ, Smeeth L. Insulin glargine and malignancy: an unwarranted alarm. Lancet. 2009;374:511-513.
-
(2009)
Lancet
, vol.374
, pp. 511-513
-
-
Pocock, S.J.1
Smeeth, L.2
-
14
-
-
77954832956
-
Doses of insulin and its analogues and cancer occurrence in insulin-treated type 2 diabetic patients
-
Mannucci E, Monami M, Balzi D, et al. Doses of insulin and its analogues and cancer occurrence in insulin-treated type 2 diabetic patients. Diabetes Care. 2010;33:1997-2003.
-
(2010)
Diabetes Care
, vol.33
, pp. 1997-2003
-
-
Mannucci, E.1
Monami, M.2
Balzi, D.3
-
15
-
-
77953539812
-
Long-term metformin use is associated with decreased risk of breast cancer
-
Bodmer M, Meier C, Krähenbühl S, Jick SS, Meier CR, Meier CR. Long-term metformin use is associated with decreased risk of breast cancer. Diabetes Care. 2010;33:1304-1308.
-
(2010)
Diabetes Care
, vol.33
, pp. 1304-1308
-
-
Bodmer, M.1
Meier, C.2
Krähenbühl, S.3
Jick, S.S.4
Meier, C.R.5
Meier, C.R.6
-
16
-
-
77954559516
-
Glycated hemoglobin and antidiabetic strategies as risk factors for hepatocellular carcinoma
-
Donadon V, Balbi M, Valent F, Avogaro A. Glycated hemoglobin and antidiabetic strategies as risk factors for hepatocellular carcinoma. World J Gastroenterol. 2010;16:3025-3032.
-
(2010)
World J Gastroenterol
, vol.16
, pp. 3025-3032
-
-
Donadon, V.1
Balbi, M.2
Valent, F.3
Avogaro, A.4
-
17
-
-
77955560604
-
Diabetes, prediabetes and cancer mortality
-
DECODE Study Group
-
Zhou XH, Qiao Q, Zethelius B, et al; DECODE Study Group. Diabetes, prediabetes and cancer mortality. Diabetologia. 2010;53:1867-1876.
-
(2010)
Diabetologia
, vol.53
, pp. 1867-1876
-
-
Zhou, X.H.1
Qiao, Q.2
Zethelius, B.3
-
18
-
-
78650857644
-
The effects of type 2 diabetes and hypertension on changes in serum prostate specific antigen levels: Results from the Olmsted County study
-
Wallner LP, Morgenstern H, McGree ME, et al. The effects of type 2 diabetes and hypertension on changes in serum prostate specific antigen levels: results from the Olmsted County study. Urology. 2011;77:137-141.
-
(2011)
Urology
, vol.77
, pp. 137-141
-
-
Wallner, L.P.1
Morgenstern, H.2
McGree, M.E.3
-
19
-
-
78649601393
-
Association of diabetes mellitus with prostate cancer: Nested case-control study (prostate testing for cancer and treatment study)
-
Turner EL, Lane JA, Donovan JL, et al. Association of diabetes mellitus with prostate cancer: nested case-control study (prostate testing for cancer and treatment study). Int J Cancer. 2011;128:440-446.
-
(2011)
Int J Cancer
, vol.128
, pp. 440-446
-
-
Turner, E.L.1
Lane, J.A.2
Donovan, J.L.3
-
20
-
-
23844551318
-
Role of the growth hormone/insulin-like growth factor system in mammalian aging
-
DOI 10.1210/en.2005-0411
-
Bartke A. Minireview: role of the growth hormone/ insulin-like growth factor system in mammalian aging. Endocrinology. 2005;146:3718-3723. (Pubitemid 41175738)
-
(2005)
Endocrinology
, vol.146
, Issue.9
, pp. 3718-3723
-
-
Bartke, A.1
-
21
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
DOI 10.1126/science.1099196
-
Cohen HY, Miller C, Bitterman KJ, et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science. 2004;305:390-392. (Pubitemid 38938153)
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
De Cabo, R.9
Sinclair, D.A.10
-
22
-
-
0036606952
-
A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan
-
DOI 10.1016/S0168-9525(02)02696-3, PII S0168952502026963
-
Carter CS, Ramsey MM, Sonntag WE. A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan. Trends Genet. 2002;18:295-301. (Pubitemid 34607119)
-
(2002)
Trends in Genetics
, vol.18
, Issue.6
, pp. 295-301
-
-
Carter, C.S.1
Ramsey, M.M.2
Sonntag, W.E.3
-
23
-
-
13944269223
-
The plasticity of aging: Insights from long-lived mutants
-
DOI 10.1016/j.cell.2005.02.002
-
Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell. 2005;120:449-460. (Pubitemid 40269760)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 449-460
-
-
Kenyon, C.1
-
24
-
-
42149141146
-
Functionally significant insulin-like growth factor I receptor mutations in centenarians
-
DOI 10.1073/pnas.0705467105
-
Suh Y, Atzmon G, Cho MO, et al. Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proc Natl Acad Sci USA. 2008;105:3438-3442. (Pubitemid 351723571)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.9
, pp. 3438-3442
-
-
Suh, Y.1
Atzmon, G.2
Cho, M.-O.3
Hwang, D.4
Liu, B.5
Leahy, D.J.6
Barzilai, N.7
Cohen, P.8
-
25
-
-
33745115859
-
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and breast cancer risk: Eight years on
-
DOI 10.1677/erc.1.01219
-
Renehan AG, Harvie M, Howell A. Insulin-like growth factor (IGF)-I, IGF binding protein-3, and breast cancer risk: eight years on. Endocr Relat Cancer. 2006;13:273-278. (Pubitemid 43886658)
-
(2006)
Endocrine-Related Cancer
, vol.13
, Issue.2
, pp. 273-278
-
-
Renehan, A.G.1
Harvie, M.2
Howell, A.3
-
26
-
-
0033531765
-
Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
-
Ma J, Pollak MN, Giovannucci E, et al. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGFbinding protein-3. J Natl Cancer Inst. 1999;91:620-625. (Pubitemid 29194048)
-
(1999)
Journal of the National Cancer Institute
, vol.91
, Issue.7
, pp. 620-625
-
-
Ma, J.1
Pollak, M.N.2
Giovannucci, E.3
Chan, J.M.4
Tao, Y.5
Hennekens, C.H.6
Stampfer, M.J.7
-
27
-
-
0032499440
-
Circulating concentrations of insulin-like growth factor-I and risk of breast cancer
-
DOI 10.1016/S0140-6736(97)10384-1
-
Hankinson SE, Willett WC, Colditz GA, et al. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet. 1998;351:1393-1396. (Pubitemid 28209997)
-
(1998)
Lancet
, vol.351
, Issue.9113
, pp. 1393-1396
-
-
Hankinson, S.E.1
Willett, W.C.2
Colditz, G.A.3
Hunter, D.J.4
Michaud, D.S.5
Deroo, B.6
Rosner, B.7
Speizer, F.E.8
Pollak, M.9
-
28
-
-
0032559272
-
Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study
-
DOI 10.1126/science.279.5350.563
-
Chan JM, Stampfer MJ, Giovannucci E, et al. Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science. 1998;279:563-566. (Pubitemid 28067285)
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 563-566
-
-
Chan, J.M.1
Stampfer, M.J.2
Giovannucci, E.3
Gann, P.H.4
Ma, J.5
Wilkinson, P.6
Hennekens, C.H.7
Pollak, M.8
-
29
-
-
68549126809
-
Unraveling insulin-like growth factor binding protein-3 actions in human disease
-
Jogie-Brahim S, Feldman D, Oh Y. Unraveling insulin-like growth factor binding protein-3 actions in human disease. Endocr Rev. 2009;30:417-437.
-
(2009)
Endocr Rev
, vol.30
, pp. 417-437
-
-
Jogie-Brahim, S.1
Feldman, D.2
Oh, Y.3
-
30
-
-
0031759850
-
Mortality and cancer incidence in acromegaly: A retrospective cohort study
-
DOI 10.1210/jc.83.8.2730
-
Orme SM, McNally RJ, Cartwright RA, Belchetz PE. Mortality and cancer incidence in acromegaly: a retrospective cohort study. United KingdomAcromegaly Study Group. J Clin Endocrinol Metab. 1998;83:2730-2734. (Pubitemid 28493768)
-
(1998)
Journal of Clinical Endocrinology and Metabolism
, vol.83
, Issue.8
, pp. 2730-2734
-
-
Orme, S.M.1
Mcnally, R.J.Q.2
Cartwright, R.A.3
Belchetz, P.E.4
-
31
-
-
0037110602
-
Overexpression of the insulin-like growth factor I receptor in human colon carcinomas
-
DOI 10.1002/cncr.10945
-
Weber MM, Fottner C, Liu SB, Jung MC, Engelhardt D, Baretton GB. Overexpression of the insulinlike growth factor I receptor in human colon carcinomas. Cancer. 2002;95:2086-2095. (Pubitemid 35253369)
-
(2002)
Cancer
, vol.95
, Issue.10
, pp. 2086-2095
-
-
Weber, M.M.1
Fottner, C.2
Liu, S.B.3
Jung, M.C.4
Engelhardt, D.5
Baretton, G.B.6
-
32
-
-
0027366338
-
Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor
-
DOI 10.1073/pnas.90.23.11217
-
Sell C, Rubini M, Rubin R, Liu JP, Efstratiadis A, Baserga R. Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc Natl Acad Sci USA. 1993;90:11217-11221. (Pubitemid 23354400)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.23
, pp. 11217-11221
-
-
Sell, C.1
Rubini, M.2
Rubin, R.3
Liu, J.-P.4
Efstratiadis, A.5
Baserga, R.6
-
33
-
-
0025189619
-
Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation
-
Kaleko M, Rutter WJ, Miller AD. Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation. Mol Cell Biol. 1990;10:464-473.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 464-473
-
-
Kaleko, M.1
Rutter, W.J.2
Miller, A.D.3
-
34
-
-
69449097339
-
Emerging role of insulinlike growth factor receptor inhibitors in oncology: Early clinical trial results and future directions
-
Gualberto A, Pollak M. Emerging role of insulinlike growth factor receptor inhibitors in oncology: early clinical trial results and future directions. Oncogene. 2009;28:3009-3021.
-
(2009)
Oncogene
, vol.28
, pp. 3009-3021
-
-
Gualberto, A.1
Pollak, M.2
-
35
-
-
57749089652
-
Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival
-
Law JH, Habibi G, Hu K, et al. Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Res. 2008;68:10238-10246.
-
(2008)
Cancer Res
, vol.68
, pp. 10238-10246
-
-
Law, J.H.1
Habibi, G.2
Hu, K.3
-
36
-
-
50449153417
-
A study of the hormonal relations of epidermal mitotic activity in vitro. II. Insulin and pituitary growth hormone
-
Bullough WS. A study of the hormonal relations of epidermal mitotic activity in vitro. II. Insulin and pituitary growth hormone. Exp Cell Res. 1954;7:186-196.
-
(1954)
Exp Cell Res
, vol.7
, pp. 186-196
-
-
Bullough, W.S.1
-
37
-
-
84860423493
-
Studies on the mitosis of mouse ear epidermis in vitro. I. Effect of insulin pretreatment on epidermal mitotic activity in vitro
-
Katayama H. Studies on the mitosis of mouse ear epidermis in vitro. I. effect of insulin pretreatment on epidermal mitotic activity in vitro. Annot Zool Jpn. 1957;30:71-76.
-
(1957)
Annot Zool Jpn
, vol.30
, pp. 71-76
-
-
Katayama, H.1
-
38
-
-
77949307940
-
Mitogenic action of insulin: Friend, foe or 'frenemy'?
-
Draznin B. Mitogenic action of insulin: friend, foe or 'frenemy'? Diabetologia. 2010;53:229-233.
-
(2010)
Diabetologia
, vol.53
, pp. 229-233
-
-
Draznin, B.1
-
39
-
-
0345447402
-
Hormone responsive human breast cancer in long term tissue culture: effect of insulin
-
DOI 10.1073/pnas.73.12.4536
-
Osborne CK, Bolan G, Monaco ME, Lippman ME. Hormone responsive human breast cancer in longterm tissue culture: effect of insulin. Proc Natl Acad Sci USA. 1976;73:4536-4540. (Pubitemid 8013935)
-
(1976)
Proceedings of the National Academy of Sciences of the United States of America
, vol.73
, Issue.12
, pp. 4536-4540
-
-
Osborne, C.K.1
Bolan, G.2
Monaco, M.E.3
Lippman, M.E.4
-
42
-
-
27544434895
-
The insulin/IGF-1 signaling in mammals and its relevance to human longevity
-
DOI 10.1016/j.exger.2005.06.014, PII S0531556505001609, Metabolism, Aging and Longevity
-
Rincon M, Rudin E, Barzilai N. The insulin/IGF-1 signaling in mammals and its relevance to human longevity. Exp Gerontol. 2005;40:873-877. (Pubitemid 41540436)
-
(2005)
Experimental Gerontology
, vol.40
, Issue.11
, pp. 873-877
-
-
Rincon, M.1
Rudin, E.2
Barzilai, N.3
-
43
-
-
77949654035
-
IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer
-
Ibanez de Caceres I, Cortes-Sempere M, Moratilla C, et al. IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer. Oncogene. 2010;29:1681-1690.
-
(2010)
Oncogene
, vol.29
, pp. 1681-1690
-
-
Ibanez De Caceres, I.1
Cortes-Sempere, M.2
Moratilla, C.3
-
44
-
-
77952309862
-
Insulin- like growth factor receptor 1 (IGF1R) gene copy number is associated with survival in operable non-small-cell lung cancer: A comparison between IGF1R fluorescent in situ hybridization, protein expression, and mRNA expression
-
Dziadziuszko R, Merrick DT, Witta SE, et al. Insulin- like growth factor receptor 1 (IGF1R) gene copy number is associated with survival in operable non-small-cell lung cancer: a comparison between IGF1R fluorescent in situ hybridization, protein expression, and mRNA expression. J Clin Oncol. 2010;28:2174-2180.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2174-2180
-
-
Dziadziuszko, R.1
Merrick, D.T.2
Witta, S.E.3
-
45
-
-
74549203484
-
IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients
-
Rajski M, Zanetti-Dällenbach R, Vogel B, Herrmann R, Rochlitz C, Buess M. IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients. BMC Med. 2010;8:1.
-
(2010)
BMC Med.
, vol.8
, pp. 1
-
-
Rajski, M.1
Zanetti-Dällenbach, R.2
Vogel, B.3
Herrmann, R.4
Rochlitz, C.5
Buess, M.6
-
46
-
-
16944364325
-
Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation
-
Turner BC, Haffty BG, Narayanan L, et al. Insulin- like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation. Cancer Res. 1997;57:3079-3083. (Pubitemid 27351714)
-
(1997)
Cancer Research
, vol.57
, Issue.15
, pp. 3079-3083
-
-
Turner, B.C.1
Haffty, B.G.2
Narayanan, L.3
Yuan, J.4
Havre, P.A.5
Gumbs, A.A.6
Kaplan, L.7
Burgaud, J.-L.8
Carter, D.9
Baserga, R.10
Glazer, P.M.11
-
47
-
-
0037470152
-
Redundancy of radioresistant signaling pathways originating from insulin-like growth factor I receptor
-
DOI 10.1074/jbc.M209809200
-
Yu D, Watanabe H, Shibuya H, Miura M. Redundancy of radioresistant signaling pathways originating from insulin-like growth factor I receptor. J Biol Chem. 2003;278:6702-6709. (Pubitemid 36800657)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.9
, pp. 6702-6709
-
-
Yu, D.1
Watanabe, H.2
Shibuya, H.3
Miura, M.4
-
48
-
-
0030738695
-
Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs
-
Dunn SE, Hardman RA, Kari FW, Barrett JC. Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs. Cancer Res. 1997;57:2687-2693. (Pubitemid 27283781)
-
(1997)
Cancer Research
, vol.57
, Issue.13
, pp. 2687-2693
-
-
Dunn, S.E.1
Hardman, R.A.2
Kari, F.W.3
Barrett, J.C.4
-
49
-
-
54249117292
-
Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors
-
Buck E, Eyzaguirre A, Rosenfeld-Franklin M, et al. Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors. Cancer Res. 2008;68:8322-8332.
-
(2008)
Cancer Res
, vol.68
, pp. 8322-8332
-
-
Buck, E.1
Eyzaguirre, A.2
Rosenfeld-Franklin, M.3
-
50
-
-
46749156706
-
Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins
-
DOI 10.1172/JC134588
-
Guix M, Faber AC, Wang SE, et al. Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins. J Clin Invest. 2008;118:2609-2619. (Pubitemid 351949788)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.7
, pp. 2609-2619
-
-
Guix, M.1
Faber, A.C.2
Wang, S.E.3
Olivares, M.G.4
Song, Y.5
Qu, S.6
Rinehart, C.7
Seidel, B.8
Yee, D.9
Arteaga, C.L.10
Engelman, J.A.11
-
51
-
-
4944266313
-
High interstitial fluid pressure - An obstacle in cancer therapy
-
DOI 10.1038/nrc1456
-
Heldin CH, Rubin K, Pietras K, Ostman A. High interstitial fluid pressure - an obstacle in cancer therapy. Nat Rev Cancer. 2004;4:806-813. (Pubitemid 39331152)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.10
, pp. 806-813
-
-
Heldin, C.-H.1
Rubin, K.2
Pietras, K.3
Ostman, A.4
-
52
-
-
34249899156
-
Glargine blood biotransformation: in vitro appraisal with human insulin immunoassay
-
DOI 10.1016/j.diabet.2006.12.002, PII S1262363607000523
-
Agin A, Jeandidier N, Gasser F, Grucker D, Sapin R. Glargine blood biotransformation: in vitro appraisal with human insulin immunoassay. Diabetes Metab. 2007;33:205-212. (Pubitemid 46863409)
-
(2007)
Diabetes and Metabolism
, vol.33
, Issue.3
, pp. 205-212
-
-
Agin, A.1
Jeandidier, N.2
Gasser, F.3
Grucker, D.4
Sapin, R.5
-
53
-
-
77951703382
-
Treatment with insulin glargine (Lantus) increases the proliferative potency of the serum of patients with type-1diabetes: A pilot study on MCF-7 breast cancer cells
-
Mayer D, Chantelau E. Treatment with insulin glargine (Lantus) increases the proliferative potency of the serum of patients with type-1diabetes: a pilot study on MCF-7 breast cancer cells. Arch Physiol Biochem. 2010;116:73-78.
-
(2010)
Arch Physiol Biochem.
, vol.116
, pp. 73-78
-
-
Mayer, D.1
Chantelau, E.2
-
54
-
-
0009689416
-
A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway
-
DOI 10.1073/pnas.85.23.8943
-
Carroll RJ, Hammer RE, Chan SJ, Swift HH, Rubenstein AH, Steiner DF. A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway. Proc Natl Acad Sci USA. 1988;85:8943-8947. (Pubitemid 19001821)
-
(1988)
Proceedings of the National Academy of Sciences of the United States of America
, vol.85
, Issue.23
, pp. 8943-8947
-
-
Carroll, R.J.1
Hammer, R.E.2
Chan, S.J.3
Swift, H.H.4
Rubenstein, A.H.5
Steiner, D.F.6
-
55
-
-
0024368808
-
Partial diversion of a mutant proinsulin (B10 aspartic acid) from the regulated to the constitutive secretory pathway in transfected AtT-20 cells
-
DOI 10.1073/pnas.86.11.4107
-
Gross DJ, Halban PA, Kahn CR, Weir GC, Villa- Komaroff L. Partial diversion of a mutant proinsulin (B10 aspartic acid) from the regulated to the constitutive secretory pathway in transfected AtT-20 cells. Proc Natl Acad Sci U S A. 1989;86:4107-4111. (Pubitemid 19154745)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.11
, pp. 4107-4111
-
-
Gross, D.J.1
Halban, P.A.2
Kahn, C.R.3
Weir, G.C.4
Villa-Komaroff, L.5
-
56
-
-
0028953352
-
Long-term comparison of human insulin analogue B10Asp and soluble human insulin in IDDM patients on a basal/bolus insulin regimen
-
Nielsen FS, Jørgensen LN, Ipsen M, Voldsgaard AI, Parving HH. Long-term comparison of human insulin analogue B10Asp and soluble human insulin in IDDM patients on a basal/bolus insulin regimen. Diabetologia. 1995;38:592-598.
-
(1995)
Diabetologia
, vol.38
, pp. 592-598
-
-
Nielsen, F.S.1
Jørgensen, L.N.2
Ipsen, M.3
Voldsgaard, A.I.4
Parving, H.H.5
-
57
-
-
0027097641
-
The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake
-
Drejer K. The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake. Diabetes Metab Rev. 1992;8:259-285.
-
(1992)
Diabetes Metab Rev
, vol.8
, pp. 259-285
-
-
Drejer, K.1
-
58
-
-
0029862845
-
Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency
-
Hansen BF, Danielsen GM, Drejer K, et al. Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency. Biochem J. 1996;315(Pt 1):271-279. (Pubitemid 26113562)
-
(1996)
Biochemical Journal
, vol.315
, Issue.1
, pp. 271-279
-
-
Hansen, B.F.1
Danielsen, G.M.2
Drejer, K.3
Sorensen, A.R.4
Wiberg, F.C.5
Klein, H.H.6
Lundemose, A.G.7
-
59
-
-
0342657181
-
Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
-
Kurtzhals P, Schäffer L, Sørensen A, et al. Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use. Diabetes. 2000;49:999-1005. (Pubitemid 30349423)
-
(2000)
Diabetes
, vol.49
, Issue.6
, pp. 999-1005
-
-
Kurtzhals, P.1
Schaffer, L.2
Sorensen, A.3
Kristensen, C.4
Jonassen, I.5
Schmid, C.6
Trub, T.7
-
60
-
-
0025894102
-
Binding and biological effects of insulin, insulin analogues and insulinlike rowth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities
-
Bornfeldt KE, Gidlöf RA, Wasteson A, Lake M, kottner A, Arnqvist HJ. Binding and biological effects of insulin, insulin analogues and insulinlike rowth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities. Diabetologia. 1991;34:307-313.
-
(1991)
Diabetologia
, vol.34
, pp. 307-313
-
-
Bornfeldt, K.E.1
Gidlöf, R.A.2
Wasteson, A.3
Lake, M.4
Kottner, A.5
Arnqvist, H.J.6
-
61
-
-
0030614323
-
10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: Evidence for enhanced interactions with the insulin-like growth factor-I receptor
-
DOI 10.1002/(SICI)1098-2744(199701)18:1<19::AID-MC3>3.0.CO;2-M
-
Milazzo G, Sciacca L, Papa V, Goldfine ID, Vigneri R. ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: evidence for enhanced interactions with the insulin-like growth factor-I receptor. Mol Carcinog. 1997;18:19-25. (Pubitemid 27107371)
-
(1997)
Molecular Carcinogenesis
, vol.18
, Issue.1
, pp. 19-25
-
-
Milazzo, G.1
Sciacca, L.2
Papa, V.3
Goldfine, I.D.4
Vigneri, R.5
-
62
-
-
0025990972
-
Receptor binding and tyrosine kinase activation by insulin analogues with extreme affinities studied in human hepatoma HepG2 cells
-
Drejer K, Kruse V, Larsen UD, Hougaard P, Bjørn S, Gammeltoft S. Receptor binding and tyrosine kinase activation by insulin analogues with extreme affinities studied in human hepatoma HepG2 cells. Diabetes. 1991;40:1488-1495.
-
(1991)
Diabetes
, vol.40
, pp. 1488-1495
-
-
Drejer, K.1
Kruse, V.2
Larsen, U.D.3
Hougaard, P.4
Bjørn, S.5
Gammeltoft, S.6
-
63
-
-
0032895627
-
Differences in the cellular processing of Asp(B10) human insulin compared with human insulin and Lys(B28)Pro(B29) human insulin
-
DOI 10.1016/S0026-0495(99)90059-8
-
Hamel FG, Siford GL, Fawcett J, Chance RE, Frank BH, Duckworth WC. Differences in the cellularprocessing of AspB10 human insulin compared with human insulin and LysB28ProB29 human insulin. Metabolism. 1999;48:611-617. (Pubitemid 29230522)
-
(1999)
Metabolism: Clinical and Experimental
, vol.48
, Issue.5
, pp. 611-617
-
-
Hamel, F.G.1
Siford, G.L.2
Fawcett, J.3
Chance, R.E.4
Frank, B.H.5
Duckworth, W.C.6
-
64
-
-
33847364416
-
PI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity
-
DOI 10.1016/j.peptides.2007.01.012, PII S019697810700037X
-
Kohn WD, Micanovic R, Myers SL, et al. pIshifted insulin analogs with extended in vivo time action and favorable receptor selectivity. Peptides. 2007;28:935-948. (Pubitemid 46349342)
-
(2007)
Peptides
, vol.28
, Issue.4
, pp. 935-948
-
-
Kohn, W.D.1
Micanovic, R.2
Myers, S.L.3
Vick, A.M.4
Kahl, S.D.5
Zhang, L.6
Strifler, B.A.7
Li, S.8
Shang, J.9
Beals, J.M.10
Mayer, J.P.11
DiMarchi, R.D.12
-
65
-
-
35848933452
-
IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts
-
DOI 10.1007/s00125-007-0815-9
-
Eckardt K, May C, Koenen M, Eckel J. IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts. Diabetologia. 2007;50:2534-2543. (Pubitemid 350060636)
-
(2007)
Diabetologia
, vol.50
, Issue.12
, pp. 2534-2543
-
-
Eckardt, K.1
May, C.2
Koenen, M.3
Eckel, J.4
-
66
-
-
70450239958
-
Combined randomised controlled trial experience of malignancies in studies using insulin glargine
-
Home PD, Lagarenne P. Combined randomised controlled trial experience of malignancies in studies using insulin glargine. Diabetologia. 2009;52:2499-2506.
-
(2009)
Diabetologia
, vol.52
, pp. 2499-2506
-
-
Home, P.D.1
Lagarenne, P.2
-
67
-
-
70949084349
-
No evidence of increased risk of malignancies in patients with diabetes treated with insulin detemir: A meta-analysis
-
Dejgaard A, Lynggaard H, Råstam J, Krogsgaard Thomsen M. No evidence of increased risk of malignancies in patients with diabetes treated with insulin detemir: a meta-analysis. Diabetologia. 2009;52:2507-2512.
-
(2009)
Diabetologia
, vol.52
, pp. 2507-2512
-
-
Dejgaard, A.1
Lynggaard, H.2
Råstam, J.3
Krogsgaard Thomsen, M.4
-
68
-
-
36749121985
-
Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention)
-
Origin Trial Investigators
-
Origin Trial Investigators, Gerstein H, Yusuf S, Riddle MC, Ryden L, Bosch J. Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: the ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention). Am Heart J. 2008;155:26-32.
-
(2008)
Am Heart J.
, vol.155
, pp. 26-32
-
-
Gerstein, H.1
Yusuf, S.2
Riddle, M.C.3
Ryden, L.4
Bosch, J.5
-
69
-
-
77949411117
-
Insulin analogues and cancer risk: Cause for concern or cause célébre?
-
Pollak M, Russell-Jones D. Insulin analogues and cancer risk: cause for concern or cause célébre? Int J Clin Pract. 2010;64:628-636.
-
(2010)
Int J Clin Pract
, vol.64
, pp. 628-636
-
-
Pollak, M.1
Russell-Jones, D.2
-
70
-
-
67650504265
-
Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines
-
Shukla A, Grisouard J, Ehemann V, Hermani A, Enzmann H, Mayer D. Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines. Endocr Relat Cancer. 2009;16:429-441.
-
(2009)
Endocr Relat Cancer
, vol.16
, pp. 429-441
-
-
Shukla, A.1
Grisouard, J.2
Ehemann, V.3
Hermani, A.4
Enzmann, H.5
Mayer, D.6
-
71
-
-
77955515434
-
Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling
-
Sciacca L, Cassarino MF, Genua M, et al. Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling. Diabetologia. 2010;53:1743-1753.
-
(2010)
Diabetologia
, vol.53
, pp. 1743-1753
-
-
Sciacca, L.1
Cassarino, M.F.2
Genua, M.3
-
72
-
-
65549138380
-
Insulin analogues display IGF-1-like mitogenic and anti-apoptotic activities in cultured cancer cells
-
Weinstein D, Simon M, Yehezkel E, Laron Z, Werner H. Insulin analogues display IGF-1-like mitogenic and anti-apoptotic activities in cultured cancer cells. Diabetes Metab Res Rev. 2009;25:41-49.
-
(2009)
Diabetes Metab Res Rev
, vol.25
, pp. 41-49
-
-
Weinstein, D.1
Simon, M.2
Yehezkel, E.3
Laron, Z.4
Werner, H.5
-
73
-
-
78649320787
-
Long-acting insulin analogues elicit atypical signalling events mediated by the insulin receptor and insulin-like growth factor-I receptor
-
Yehezkel E, Weinstein D, Simon M, Sarfstein R, Laron Z, Werner H. Long-acting insulin analogues elicit atypical signalling events mediated by the insulin receptor and insulin-like growth factor-I receptor. Diabetologia. 2010;53:2667-2675.
-
(2010)
Diabetologia
, vol.53
, pp. 2667-2675
-
-
Yehezkel, E.1
Weinstein, D.2
Simon, M.3
Sarfstein, R.4
Laron, Z.5
Werner, H.6
-
74
-
-
24944566769
-
Insulin and its analogue glargine do not affect viability and proliferation of human coronary artery endothelial and smooth muscle cells
-
DOI 10.1007/s00125-005-1874-4
-
Staiger K, Staiger H, Schweitzer MA, et al. Insulin and its analogue glargine do not affect viability and proliferation of human coronary artery endothelial and smooth muscle cells. Diabetologia. 2005;48:1898-1905. (Pubitemid 41317846)
-
(2005)
Diabetologia
, vol.48
, Issue.9
, pp. 1898-1905
-
-
Staiger, K.1
Staiger, H.2
Schweitzer, M.A.3
Metzinger, E.4
Balletshofer, B.5
Haring, H.-U.6
Kellerer, M.7
-
75
-
-
47049123594
-
Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-I
-
DOI 10.1055/s-2008-1062739
-
Liefvendahl E, Arnqvist HJ. Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-1. Horm Metab Res. 2008;40:369-374. (Pubitemid 351967126)
-
(2008)
Hormone and Metabolic Research
, vol.40
, Issue.6
, pp. 369-374
-
-
Liefvendahl, E.1
Arnqvist, H.J.2
-
76
-
-
77949760139
-
In vitro metabolic and mitogenic signaling of insulin glargine and its metabolites
-
Sommerfeld MR, Müller G, Tschank G, et al. In vitro metabolic and mitogenic signaling of insulin glargine and its metabolites. PLoS One. 2010;5:e9540.
-
(2010)
PLoS One
, vol.5
-
-
Sommerfeld, M.R.1
Müller, G.2
Tschank, G.3
-
77
-
-
78649633536
-
Insulin glargine is more potent in activating the human IGF-1 receptor than human insulin and insulin detemir
-
Varewijck AJ, Goudzwaard JA, Brugts MP, Lamberts SW, Hofland LJ, Janssen JA. Insulin glargine is more potent in activating the human IGF-1 receptor than human insulin and insulin detemir. Growth Horm IGF Res. 2010;20:427-431.
-
(2010)
Growth Horm IGF Res.
, vol.20
, pp. 427-431
-
-
Varewijck, A.J.1
Goudzwaard, J.A.2
Brugts, M.P.3
Lamberts, S.W.4
Hofland, L.J.5
Janssen, J.A.6
-
78
-
-
84860421277
-
Safety analysis of basal insulins: Mitogenic potency and receptor binding
-
Poster 95
-
Hansen BF, Stidsen CE, Glendorf T, Lundby A, Hegelund AC, Bonnesen C. Safety analysis of basal insulins: mitogenic potency and receptor binding. Diabet Med. 2010;27(Suppl. 1):Poster 95.
-
(2010)
Diabet Med.
, vol.27
, Issue.SUPPL. 1
-
-
Hansen, B.F.1
Stidsen, C.E.2
Glendorf, T.3
Lundby, A.4
Hegelund, A.C.5
Bonnesen, C.6
-
79
-
-
70849120946
-
Insulin receptor isoforms and insulin receptor/insulinlike growth factor receptor hybrids in physiology and disease
-
Belfiore A, Frasca F, Pandini G, Sciacca L, Vigneri R. Insulin receptor isoforms and insulin receptor/insulinlike growth factor receptor hybrids in physiology and disease. Endocr Rev. 2009;30:586-623.
-
(2009)
Endocr Rev.
, vol.30
, pp. 586-623
-
-
Belfiore, A.1
Frasca, F.2
Pandini, G.3
Sciacca, L.4
Vigneri, R.5
|