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Volumn 6, Issue 10, 2011, Pages

Altered expression of Insulin receptor isoforms in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN RECEPTOR; INSULIN RECEPTOR A; INSULIN RECEPTOR B; MESSENGER RNA; UNCLASSIFIED DRUG; INSR PROTEIN, HUMAN; ISOPROTEIN; LEUKOCYTE ANTIGEN; SOMATOMEDIN C; TUMOR MARKER;

EID: 80055026624     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026177     Document Type: Article
Times cited : (53)

References (33)
  • 1
    • 0024548162 scopus 로고
    • Structure of the human insulin receptor gene and characterization of its promoter
    • Seino S, Seino M, Nishi S, Bell GI, (1989) Structure of the human insulin receptor gene and characterization of its promoter. Proc Natl Acad Sci U S A 86 (1): 114-8.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , Issue.1 , pp. 114-118
    • Seino, S.1    Seino, M.2    Nishi, S.3    Bell, G.I.4
  • 2
    • 0024403208 scopus 로고
    • Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man
    • Moller DE, Yokota A, Caro JF, Flier JS, (1989) Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man. Mol Endocrinol 3 (8): 1263-9.
    • (1989) Mol Endocrinol , vol.3 , Issue.8 , pp. 1263-1269
    • Moller, D.E.1    Yokota, A.2    Caro, J.F.3    Flier, J.S.4
  • 3
    • 0032932822 scopus 로고    scopus 로고
    • Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells
    • Frasca F, Pandini G, Scalia P, Sciacca L, Mineo R, et al. (1999) Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells. Mol Cell Biol 19 (5): 3278-88.
    • (1999) Mol Cell Biol , vol.19 , Issue.5 , pp. 3278-3288
    • Frasca, F.1    Pandini, G.2    Scalia, P.3    Sciacca, L.4    Mineo, R.5
  • 4
    • 0025801714 scopus 로고
    • Altered expression of insulin receptor types A and B in the skeletal muscle of non-insulin-dependent diabetes mellitus patients
    • Mosthaf L, Vogt B, Haring HU, Ullrich A, (1991) Altered expression of insulin receptor types A and B in the skeletal muscle of non-insulin-dependent diabetes mellitus patients. Proc Natl Acad Sci U S A 88 (11): 4728-30.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.11 , pp. 4728-4730
    • Mosthaf, L.1    Vogt, B.2    Haring, H.U.3    Ullrich, A.4
  • 5
    • 0026348452 scopus 로고
    • Altered expression of the two naturally occurring human insulin receptor variants in isolated adipocytes of non-insulin-dependent diabetes mellitus patients
    • Sesti G, Marini MA, Tullio AN, Montemurro A, Borboni P, et al. (1991) Altered expression of the two naturally occurring human insulin receptor variants in isolated adipocytes of non-insulin-dependent diabetes mellitus patients. Biochem Biophys Res Commun 181 (3): 1419-24.
    • (1991) Biochem Biophys Res Commun , vol.181 , Issue.3 , pp. 1419-1424
    • Sesti, G.1    Marini, M.A.2    Tullio, A.N.3    Montemurro, A.4    Borboni, P.5
  • 6
    • 0027322636 scopus 로고
    • Altered pattern of insulin receptor isotypes in skeletal muscle membranes of type 2 (non-insulin-dependent) diabetic subjects
    • Kellerer M, Sesti G, Seffer E, Obermaier-Kusser B, Pongratz DE, et al. (1993) Altered pattern of insulin receptor isotypes in skeletal muscle membranes of type 2 (non-insulin-dependent) diabetic subjects. Diabetologia 36 (7): 628-32.
    • (1993) Diabetologia , vol.36 , Issue.7 , pp. 628-632
    • Kellerer, M.1    Sesti, G.2    Seffer, E.3    Obermaier-Kusser, B.4    Pongratz, D.E.5
  • 7
    • 0032800850 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: Evidence for a second mechanism of IGF-I signaling
    • Pandini G, Vigneri R, Costantino A, Frasca F, Ippolito A, et al. (1999) Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: Evidence for a second mechanism of IGF-I signaling. Clin Cancer Res 5 (7): 1935-44.
    • (1999) Clin Cancer Res , vol.5 , Issue.7 , pp. 1935-1944
    • Pandini, G.1    Vigneri, R.2    Costantino, A.3    Frasca, F.4    Ippolito, A.5
  • 9
    • 0142180099 scopus 로고    scopus 로고
    • Differential gene expression induced by insulin and insulin-like growth factor-II through the insulin receptor isoform A
    • Pandini G, Medico E, Conte E, Sciacca L, Vigneri R, et al. (2003) Differential gene expression induced by insulin and insulin-like growth factor-II through the insulin receptor isoform A. J Biol Chem 278 (43): 42178-89.
    • (2003) J Biol Chem , vol.278 , Issue.43 , pp. 42178-42189
    • Pandini, G.1    Medico, E.2    Conte, E.3    Sciacca, L.4    Vigneri, R.5
  • 10
    • 0028102133 scopus 로고
    • Modulation of insulin receptor signalling: Significance of altered receptor isoform patterns and mechanism of hyperglycaemia-induced receptor modulation
    • Haring HU, Kellerer M, Mosthaf L, (1994) Modulation of insulin receptor signalling: Significance of altered receptor isoform patterns and mechanism of hyperglycaemia-induced receptor modulation. Diabetologia 37 (Suppl 2): S149-54.
    • (1994) Diabetologia , vol.37 , Issue.SUPPL. 2 , pp. 149-154
    • Haring, H.U.1    Kellerer, M.2    Mosthaf, L.3
  • 11
    • 0024465470 scopus 로고
    • Immunological relationships between receptors for insulin and insulin-like growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors involving hybrids with insulin receptors
    • Soos MA, Siddle K, (1989) Immunological relationships between receptors for insulin and insulin-like growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors involving hybrids with insulin receptors. Biochem J 263 (2): 553-63.
    • (1989) Biochem J , vol.263 , Issue.2 , pp. 553-563
    • Soos, M.A.1    Siddle, K.2
  • 12
    • 56749184290 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor signalling in neoplasia
    • Pollak M, (2008) Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 8 (12): 915-28.
    • (2008) Nat Rev Cancer , vol.8 , Issue.12 , pp. 915-928
    • Pollak, M.1
  • 13
    • 0027732788 scopus 로고
    • Immunological studies of type I IGF receptors and insulin receptors: Characterization of hybrid and atypical receptor subtypes
    • Soos MA, Nave BT, Siddle K, (1993) Immunological studies of type I IGF receptors and insulin receptors: Characterization of hybrid and atypical receptor subtypes. Adv Exp Med Biol 343: 145-57.
    • (1993) Adv Exp Med Biol , vol.343 , pp. 145-157
    • Soos, M.A.1    Nave, B.T.2    Siddle, K.3
  • 14
    • 0025131648 scopus 로고
    • Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. characterization of hybrid receptors in transfected cells
    • Soos MA, Whittaker J, Lammers R, Ullrich A, Siddle K, (1990) Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. characterization of hybrid receptors in transfected cells. Biochem J 270 (2): 383-90.
    • (1990) Biochem J , vol.270 , Issue.2 , pp. 383-390
    • Soos, M.A.1    Whittaker, J.2    Lammers, R.3    Ullrich, A.4    Siddle, K.5
  • 15
    • 77953973648 scopus 로고    scopus 로고
    • Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy
    • Ulanet DB, Ludwig DL, Kahn CR, Hanahan D, (2010) Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy. Proc Natl Acad Sci U S A 107 (24): 10791-8.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.24 , pp. 10791-10798
    • Ulanet, D.B.1    Ludwig, D.L.2    Kahn, C.R.3    Hanahan, D.4
  • 16
    • 79551547098 scopus 로고    scopus 로고
    • Dual IGF-I/II-neutralizing antibody MEDI-573 potently inhibits IGF signaling and tumor growth
    • Gao J, Chesebrough JW, Cartlidge SA, Ricketts SA, Incognito L, et al. (2011) Dual IGF-I/II-neutralizing antibody MEDI-573 potently inhibits IGF signaling and tumor growth. Cancer Res 71 (3): 1029-40.
    • (2011) Cancer Res , vol.71 , Issue.3 , pp. 1029-1040
    • Gao, J.1    Chesebrough, J.W.2    Cartlidge, S.A.3    Ricketts, S.A.4    Incognito, L.5
  • 17
    • 77950308839 scopus 로고    scopus 로고
    • Breast cancer molecular profiling with single sample predictors: A retrospective analysis
    • Weigelt B, Mackay A, A'hern R, Natrajan R, Tan DS, et al. (2010) Breast cancer molecular profiling with single sample predictors: A retrospective analysis. Lancet Oncol 11 (4): 339-49.
    • (2010) Lancet Oncol , vol.11 , Issue.4 , pp. 339-349
    • Weigelt, B.1    Mackay, A.2    A'hern, R.3    Natrajan, R.4    Tan, D.S.5
  • 18
    • 19944422061 scopus 로고    scopus 로고
    • A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
    • Paik S, Shak S, Tang G, Kim C, Baker J, et al. (2004) A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 351 (27): 2817-26.
    • (2004) N Engl J Med , vol.351 , Issue.27 , pp. 2817-2826
    • Paik, S.1    Shak, S.2    Tang, G.3    Kim, C.4    Baker, J.5
  • 20
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L, (2009) Gene-expression signatures in breast cancer. N Engl J Med 360 (8): 790-800.
    • (2009) N Engl J Med , vol.360 , Issue.8 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 21
    • 33847147996 scopus 로고    scopus 로고
    • The combination of letrozole and trastuzumab as first or second-line biological therapy produces durable responses in a subset of HER2 positive and ER positive advanced breast cancers
    • Marcom PK, Isaacs C, Harris L, Wong ZW, Kommarreddy A, et al. (2007) The combination of letrozole and trastuzumab as first or second-line biological therapy produces durable responses in a subset of HER2 positive and ER positive advanced breast cancers. Breast Cancer Res Treat 102 (1): 43-9.
    • (2007) Breast Cancer Res Treat , vol.102 , Issue.1 , pp. 43-49
    • Marcom, P.K.1    Isaacs, C.2    Harris, L.3    Wong, Z.W.4    Kommarreddy, A.5
  • 22
    • 51649091930 scopus 로고    scopus 로고
    • Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis
    • Creighton CJ, Casa A, Lazard Z, Huang S, Tsimelzon A, et al. (2008) Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis. J Clin Oncol 26 (25): 4078-85.
    • (2008) J Clin Oncol , vol.26 , Issue.25 , pp. 4078-4085
    • Creighton, C.J.1    Casa, A.2    Lazard, Z.3    Huang, S.4    Tsimelzon, A.5
  • 23
    • 0032709249 scopus 로고    scopus 로고
    • Insulin/IGF-I hybrid receptors play a major role in IGF-I signaling in thyroid cancer
    • Belfiore A, Pandini G, Vella V, Squatrito S, Vigneri R, (1999) Insulin/IGF-I hybrid receptors play a major role in IGF-I signaling in thyroid cancer. Biochimie 81 (4): 403-7.
    • (1999) Biochimie , vol.81 , Issue.4 , pp. 403-407
    • Belfiore, A.1    Pandini, G.2    Vella, V.3    Squatrito, S.4    Vigneri, R.5
  • 24
    • 33745924420 scopus 로고    scopus 로고
    • Inhibition of insulin receptor isoform-A signalling restores sensitivity to gefitinib in previously de novo resistant colon cancer cells
    • Jones HE, Gee JM, Barrow D, Tonge D, Holloway B, et al. (2006) Inhibition of insulin receptor isoform-A signalling restores sensitivity to gefitinib in previously de novo resistant colon cancer cells. Br J Cancer 95 (2): 172-80.
    • (2006) Br J Cancer , vol.95 , Issue.2 , pp. 172-180
    • Jones, H.E.1    Gee, J.M.2    Barrow, D.3    Tonge, D.4    Holloway, B.5
  • 25
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, et al. (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature 415 (6871): 530-6.
    • (2002) Nature , vol.415 , Issue.6871 , pp. 530-536
    • van 't Veer, L.J.1    Dai, H.2    van de Vijver, M.J.3    He, Y.D.4    Hart, A.A.5
  • 26
    • 62449131093 scopus 로고    scopus 로고
    • Supervised risk predictor of breast cancer based on intrinsic subtypes
    • Parker JS, Mullins M, Cheang MC, Leung S, Voduc D, et al. (2009) Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol 27 (8): 1160-7.
    • (2009) J Clin Oncol , vol.27 , Issue.8 , pp. 1160-1167
    • Parker, J.S.1    Mullins, M.2    Cheang, M.C.3    Leung, S.4    Voduc, D.5
  • 27
    • 33746910265 scopus 로고    scopus 로고
    • Concordance among gene-expression-based predictors for breast cancer
    • Fan C, Oh DS, Wessels L, Weigelt B, Nuyten DS, et al. (2006) Concordance among gene-expression-based predictors for breast cancer. N Engl J Med 355 (6): 560-9.
    • (2006) N Engl J Med , vol.355 , Issue.6 , pp. 560-569
    • Fan, C.1    Oh, D.S.2    Wessels, L.3    Weigelt, B.4    Nuyten, D.S.5
  • 28
    • 33645820586 scopus 로고    scopus 로고
    • Estrogen-regulated genes predict survival in hormone receptor-positive breast cancers
    • Oh DS, Troester MA, Usary J, Hu Z, He X, et al. (2006) Estrogen-regulated genes predict survival in hormone receptor-positive breast cancers. J Clin Oncol 24 (11): 1656-64.
    • (2006) J Clin Oncol , vol.24 , Issue.11 , pp. 1656-1664
    • Oh, D.S.1    Troester, M.A.2    Usary, J.3    Hu, Z.4    He, X.5
  • 29
    • 66849140730 scopus 로고    scopus 로고
    • Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer
    • Cheang MC, Chia SK, Voduc D, Gao D, Leung S, et al. (2009) Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst 101 (10): 736-50.
    • (2009) J Natl Cancer Inst , vol.101 , Issue.10 , pp. 736-750
    • Cheang, M.C.1    Chia, S.K.2    Voduc, D.3    Gao, D.4    Leung, S.5
  • 31
    • 0026710682 scopus 로고
    • Insulin receptor expression and function in human breast cancer cell lines
    • Milazzo G, Giorgino F, Damante G, Sung C, Stampfer MR, et al. (1992) Insulin receptor expression and function in human breast cancer cell lines. Cancer Res 52: 3924-3930.
    • (1992) Cancer Res , vol.52 , pp. 3924-3930
    • Milazzo, G.1    Giorgino, F.2    Damante, G.3    Sung, C.4    Stampfer, M.R.5
  • 32
    • 0036148531 scopus 로고    scopus 로고
    • A novel autocrine loop involving IGF-II and the insulin receptor isoform-A stimulates growth of thyroid cancer
    • Vella V, Pandini G, Sciacca L, Mineo R, Vigneri R, et al. (2002) A novel autocrine loop involving IGF-II and the insulin receptor isoform-A stimulates growth of thyroid cancer. J Clin Endocrin Metab 87: 245-254.
    • (2002) J Clin Endocrin Metab , vol.87 , pp. 245-254
    • Vella, V.1    Pandini, G.2    Sciacca, L.3    Mineo, R.4    Vigneri, R.5
  • 33
    • 79952294885 scopus 로고    scopus 로고
    • Insulin receptor isoforms and insulin-like growth factor receptor in human follicular cell precursors from papillary thyroid cancer and normal thyroid
    • Malaguarnera R, Frasca F, Garozzo A, Giani F, Pandini G, et al. (2001) Insulin receptor isoforms and insulin-like growth factor receptor in human follicular cell precursors from papillary thyroid cancer and normal thyroid. J Clin Endocrin Metab 96: 766-774.
    • (2001) J Clin Endocrin Metab , vol.96 , pp. 766-774
    • Malaguarnera, R.1    Frasca, F.2    Garozzo, A.3    Giani, F.4    Pandini, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.