Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity

Neuropharmacology

Volumn 76, Issue PART C, 2014, Pages 610-627

  Edelmann, Elke ^a   Leßmann, Volkmar ^a,b   Brigadski, Tanja ^a,b  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b Center for Behavioral Brain Sciences   (Germany)

Author keywords

BDNF secretion; BDNF dependent synaptic plasticity; Long term potentiation; LTP; Mossy fiber LTP; Neurotrophin; Spike timing; STDP; Synaptic plasticity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MESSENGER RNA;

BDNF GENE; BRAIN NERVE CELL; BRAIN REGION; CELLULAR DISTRIBUTION; HUMAN; LONG TERM MEMORY; LONG TERM POTENTIATION; MOSSY FIBER; NERVE CELL PLASTICITY; NEUROMODULATION; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; REGULATOR GENE; REVIEW; SIGNAL TRANSDUCTION;

BDNF SECRETION; BDNF-DEPENDENT SYNAPTIC PLASTICITY; LONG-TERM POTENTIATION; LTP; MOSSY FIBER LTP; NEUROTROPHIN; SPIKE TIMING; STDP; SYNAPTIC PLASTICITY;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; NEURONAL PLASTICITY; POST-SYNAPTIC DENSITY; PRESYNAPTIC TERMINALS;

EID: 84890427492     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.05.043     Document Type: Review

References (245)

1. W.C. Abraham Metaplasticity: tuning synapses and networks for plasticity Nat. Rev. Neurosci. 9 2008 387
2. N. Adachi, T. Numakawa, E. Kumamaru, C. Itami, S. Chiba, Y. Iijima, M. Richards, R. Katoh-Semba, and H. Kunugi Phencyclidine-induced decrease of synaptic connectivity via inhibition of BDNF secretion in cultured cortical neurons Cereb. Cortex 23 2013 847 858
3. G. Aicardi, E. Argilli, S. Cappello, S. Santi, M. Riccio, H. Thoenen, and M. Canossa Induction of long-term potentiation and depression is reflected by corresponding changes in secretion of endogenous brain-derived neurotrophic factor Proc. Natl. Acad. Sci. U. S. A. 101 2004 15788 15792
4. Y. Akaneya, T. Tsumoto, S. Kinoshita, and H. Hatanaka Brain-derived neurotrophic factor enhances long-term potentiation in rat visual cortex J. Neurosci. 17 1997 6707 6716
5. J. Alder, S. Thakker-Varia, R.A. Crozier, A. Shaheen, M.R. Plummer, and I.B. Black Early presynaptic and late postsynaptic components contribute independently to brain-derived neurotrophic factor-induced synaptic plasticity J. Neurosci. 25 2005 3080 3085
6. M.D. Amaral, and L. Pozzo-Miller TRPC3 channels are necessary for brain-derived neurotrophic factor to activate a nonselective cationic current and to induce dendritic spine formation J. Neurosci. 27 2007 5179 5189
7. J.J. An, K. Gharami, G.Y. Liao, N.H. Woo, A.G. Lau, F. Vanevski, E.R. Torre, K.R. Jones, Y. Feng, B. Lu, and B. Xu Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons Cell 134 2008 175 187
8. C. Aoki, K. Wu, A. Elste, G. Len, S. Lin, G. McAuliffe, and I.B. Black Localization of brain-derived neurotrophic factor and TrkB receptors to postsynaptic densities of adult rat cerebral cortex J. Neurosci. Res. 59 2000 454 463
9. S. Arancibia, A. Lecomte, M. Silhol, E. Aliaga, and L. Tapia-Arancibia In vivo brain-derived neurotrophic factor release and tyrosine kinase B receptor expression in the supraoptic nucleus after osmotic stress stimulus in rats Neuroscience 146 2007 864 873
10. A. Artola, and W. Singer The involvement of n-methyl-d-aspartate receptors in induction and maintenance of long-term potentiation in rat visual cortex Eur. J. Neurosci. 2 1990 254 269
11. O. Avwenagha, M.M. Bird, A.R. Lieberman, Q. Yan, and G. Campbell Patterns of expression of brain-derived neurotrophic factor and tyrosine kinase B mRNAs and distribution and ultrastructural localization of their proteins in the visual pathway of the adult rat Neuroscience 140 2006 913 928
12. F. Ba, J. Ren, and J.J. Greer Brain-derived neurotrophic factor release with neuronal activity in fetal rats Neuroreport 16 2005 141 143
13. H. Babu, G. Ramirez-Rodriguez, K. Fabel, J. Bischofberger, and G. Kempermann Synaptic network activity induces neuronal differentiation of adult hippocampal precursor cells through BDNF signaling Front Neurosci. 3 2009 49
14. A. Bachis, V. Avdoshina, L. Zecca, M. Parsadanian, and I. Mocchetti Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons J. Neurosci. 32 2012 9477 9484
15. A. Balkowiec, and D.M. Katz Activity-dependent release of endogenous brain-derived neurotrophic factor from primary sensory neurons detected by ELISA in situ J. Neurosci. 20 2000 7417 7423
16. A. Balkowiec, and D.M. Katz Cellular mechanisms regulating activity-dependent release of native brain-derived neurotrophic factor from hippocampal neurons J. Neurosci. 22 2002 10399 10407
17. A. Barco, S.L. Patterson, J.M. Alarcon, P. Gromova, M. Mata-Roig, A. Morozov, and E.R. Kandel Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture Neuron 48 2005 123 137
18. A. Barco, A.M. Lopez de, and J.M. Alarcon Synapse-specific stabilization of plasticity processes: the synaptic tagging and capture hypothesis revisited 10 years later Neurosci. Biobehav Rev. 32 2008 831 851
19. S. Barg, C.S. Olofsson, J. Schriever-Abeln, A. Wendt, S. Gebre-Medhin, E. Renstrom, and P. Rorsman Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells Neuron 33 2002 287 299
20. G. Barrionuevo, and T.H. Brown Associative long-term potentiation in hippocampal slices Proc. Natl. Acad. Sci. U. S. A. 80 1983 7347 7351
21. M. Bergami, S. Santi, E. Formaggio, C. Cagnoli, C. Verderio, R. Blum, B. Berninger, M. Matteoli, and M. Canossa Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes J. Cell Biol. 183 2008 213 221
22. J. Bischofberger, D. Engel, M. Frotscher, and P. Jonas Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network Pflugers Arch. 453 2006 361 372
23. T.V. Bliss, and G.L. Collingridge A synaptic model of memory: long-term potentiation in the hippocampus Nature 361 1993 31 39
24. C.R. Bramham, and E. Messaoudi BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis Prog. Neurobiol. 76 2005 99 125
25. T. Brigadski, M. Hartmann, and V. Lessmann Differential vesicular targeting and time course of synaptic secretion of the mammalian neurotrophins J. Neurosci. 25 2005 7601 7614
26. K.A. Buchanan, and J.R. Mellor The activity requirements for spike timing-dependent plasticity in the hippocampus Front Synaptic Neurosci. 2 2010 11
27. I. Buldyrev, N.M. Tanner, H.Y. Hsieh, E.G. Dodd, L.T. Nguyen, and A. Balkowiec Calcitonin gene-related peptide enhances release of native brain-derived neurotrophic factor from trigeminal ganglion neurons J. Neurochem. 99 2006 1338 1350
28. R. Butowt, and C.S. von Bartheld Sorting of internalized neurotrophins into an endocytic transcytosis pathway via the Golgi system: ultrastructural analysis in retinal ganglion cells7 J. Neurosci. 21 2001 8915 8930
29. R.J. Cabelli, D.L. Shelton, R.A. Segal, and C.J. Shatz Blockade of endogenous ligands of trkB inhibits formation of ocular dominance columns Neuron 19 1997 63 76
30. M.V. Caldeira, C.V. Melo, D.B. Pereira, R. Carvalho, S.S. Correia, D.S. Backos, A.L. Carvalho, J.A. Esteban, and C.B. Duarte Brain-derived neurotrophic factor regulates the expression and synaptic delivery of alpha-amino-3-hydroxy- 5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons J. Biol. Chem. 282 2007 12619 12628
31. M. Canossa, O. Griesbeck, B. Berninger, G. Campana, R. Kolbeck, and H. Thoenen Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity 5 Proc. Natl. Acad. Sci. U. S. A. 94 1997 13279 13286
32. M. Canossa, A. Gartner, G. Campana, N. Inagaki, and H. Thoenen Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways EMBO J. 20 2001 1640 1650
33. M. Canossa, E. Giordano, S. Cappello, C. Guarnieri, and S. Ferri Nitric oxide down-regulates brain-derived neurotrophic factor secretion in cultured hippocampal neurons Proc. Natl. Acad. Sci. U. S. A. 99 2002 3282 3287
34. A.M. Canudas, S. Pezzi, J.M. Canals, M. Pallas, and J. Alberch Endogenous brain-derived neurotrophic factor protects dopaminergic nigral neurons against transneuronal degeneration induced by striatal excitotoxic injury Brain Res. Mol. Brain Res. 134 2005 147 154
35. N. Caporale, and Y. Dan Spike timing-dependent plasticity: a Hebbian learning rule Annu. Rev. Neurosci. 31 2008 25 46
36. S. Capsoni, E. Tongiorgi, A. Cattaneo, and L. Domenici Differential regulation of brain-derived neurotrophic factor messenger RNA cellular expression in the adult rat visual cortex Neuroscience 93 1999 1033 1040
37. + channel activation induces both action potentials in utricular hair cells and brain-derived neurotrophic factor release in the rat utricle during a restricted period of development J. Physiol. 553 2003 113 123
38. G. Chen, R. Kolbeck, Y.A. Barde, T. Bonhoeffer, and A. Kossel Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation J. Neurosci. 19 1999 7983 7990
39. Z.Y. Chen, D. Jing, K.G. Bath, A. Ieraci, T. Khan, C.J. Siao, D.G. Herrera, M. Toth, C. Yang, B.S. McEwen, B.L. Hempstead, and F.S. Lee Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior Science 314 2006 140 143
40. S. Chourbaji, C. Brandwein, and P. Gass Altering BDNF expression by genetics and/or environment: impact for emotional and depression-like behaviour in laboratory mice Neurosci. Biobehav Rev. 35 2011 599 611
41. G. Chytrova, Z. Ying, and F. Gomez-Pinilla Exercise normalizes levels of MAG and Nogo-A growth inhibitors after brain trauma Eur. J. Neurosci. 27 2008 1 11
42. A.N. Clarkson, J.J. Overman, S. Zhong, R. Mueller, G. Lynch, and S.T. Carmichael AMPA receptor-induced local brain-derived neurotrophic factor signaling mediates motor recovery after stroke 1 J. Neurosci. 31 2011 3766 3775
43. J.M. Conner, J.C. Lauterborn, Q. Yan, C.M. Gall, and S. Varon Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport J. Neurosci. 17 1997 2295 2313
44. B. Connor, and M. Dragunow The role of neuronal growth factors in neurodegenerative disorders of the human brain Brain Res. Brain Res. Rev. 27 1998 1 39
45. J.A. Coull, S. Beggs, D. Boudreau, D. Boivin, M. Tsuda, K. Inoue, C. Gravel, M.W. Salter, and K.Y. De BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain Nature 438 2005 1017 1021
46. S.D. Croll, C.R. Chesnutt, J.S. Rudge, A. Acheson, T.E. Ryan, J.A. Siuciak, P.S. DiStefano, S.J. Wiegand, and R.M. Lindsay Co-infusion with a TrkB-Fc receptor body carrier enhances BDNF distribution in the adult rat brain 3 Exp. Neurol. 152 1998 20 33
47. W.J. de Wit, R.F. Toonen, and M. Verhage Matrix-dependent local retention of secretory vesicle cargo in cortical neurons J. Neurosci. 29 2009 23 37
48. C. Dean, H. Liu, F.M. Dunning, P.Y. Chang, M.B. Jackson, and E.R. Chapman Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release Nat. Neurosci. 12 2009 767 776
49. C. Dean, H. Liu, T. Staudt, M.A. Stahlberg, S. Vingill, J. Buckers, D. Kamin, J. Engelhardt, M.B. Jackson, S.W. Hell, and E.R. Chapman Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity J. Neurosci. 32 2012 5398 5413
50. S. Dieni, T. Matsumoto, M. Dekkers, S. Rauskolb, M.S. Ionescu, R. Deogracias, E.D. Gundelfinger, M. Kojima, S. Nestel, M. Frotscher, and Y.A. Barde BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons J. Cell Biol. 196 2012 775 788
51. J.L. Du, H.P. Wei, Z.R. Wang, S.T. Wong, and M.M. Poo Long-range retrograde spread of LTP and LTD from optic tectum to retina Proc. Natl. Acad. Sci. U. S. A. 106 2009 18890 18896
52. M.M. Dugich-Djordjevic, C. Peterson, F. Isono, F. Ohsawa, H.R. Widmer, T.L. Denton, G.L. Bennett, and F. Hefti Immunohistochemical visualization of brain-derived neurotrophic factor in the rat brain Eur. J. Neurosci. 7 1995 1831 1839
53. I. Duguid, and P.J. Sjostrom Novel presynaptic mechanisms for coincidence detection in synaptic plasticity Curr. Opin. Neurobiol. 16 2006 312 322
54. E. Edelmann, and V. Lessmann Dopamine modulates spike timing-dependent plasticity and action potential properties in CA1 pyramidal neurons of acute rat hippocampal slices Front Synaptic Neurosci. 3 2011 6
55. E. Edelmann, and V. Lessmann Dopamine regulates intrinsic excitability thereby gating successful induction of spike timing-dependent plasticity in CA1 of the hippocampus Front. Neurosci 7 25 2013
56. M.F. Egan, M. Kojima, J.H. Callicott, T.E. Goldberg, B.S. Kolachana, A. Bertolino, E. Zaitsev, B. Gold, D. Goldman, M. Dean, B. Lu, and D.R. Weinberger The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function Cell 112 2003 257 269
57. C.N. English, A.J. Vigers, and K.R. Jones Genetic evidence that brain-derived neurotrophic factor mediates competitive interactions between individual cortical neurons2 Proc. Natl. Acad. Sci. U. S. A. 109 2012 19456 19461
58. P. Ernfors, C. Wetmore, L. Olson, and H. Persson Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family Neuron 5 1990 511 526
59. T. Falkenberg, P. Ernfors, H. Persson, and N. Lindefors Cortical transynaptic activation of tyrosine kinase receptor trkB messenger RNA expression in rat hippocampus Neuroscience 51 1992 883 889
60. A. Faroni, F. Calabrese, M.A. Riva, G. Terenghi, and V. Magnaghi Baclofen modulates the expression and release of neurotrophins in schwann-like adipose stem cells J. Mol. Neurosci. 49 2013 233 243
61. J.P. Fawcett, R. Aloyz, J.H. McLean, S. Pareek, F.D. Miller, P.S. McPherson, and R.A. Murphy Detection of brain-derived neurotrophic factor in a vesicular fraction of brain synaptosomes9 J. Biol. Chem. 272 1997 8837 8840
62. D.E. Feldman The spike-timing dependence of plasticity Neuron 75 2012 556 571
63. (-) homeostasis Nat. Neurosci. 16 2013 183 192
64. A. Figurov, L.D. Pozzo-Miller, P. Olafsson, T. Wang, and B. Lu Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus Nature 381 1996 706 709
65. H. Fiorentino, N. Kuczewski, D. Diabira, N. Ferrand, M.N. Pangalos, C. Porcher, and J.L. Gaiarsa GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses J. Neurosci. 29 2009 11650 11661
66. D.A. Fortin, T. Srivastava, D. Dwarakanath, P. Pierre, S. Nygaard, V.A. Derkach, and T.R. Soderling Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors J. Neurosci. 32 2012 8127 8137
67. U. Frey, and R.G. Morris Synaptic tagging and long-term potentiation Nature 385 1997 533 536
68. H. Fujimura, C.A. Altar, R. Chen, T. Nakamura, T. Nakahashi, J. Kambayashi, B. Sun, and N.N. Tandon Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation Thromb. Haemost. 87 2002 728 734
69. S. Fujisawa, M.K. Yamada, N. Nishiyama, N. Matsuki, and Y. Ikegaya BDNF boosts spike fidelity in chaotic neural oscillations Biophys. J. 86 2004 1820 1828
70. A. Gartner, and V. Staiger Neurotrophin secretion from hippocampal neurons evoked by long-term-potentiation-inducing electrical stimulation patterns2 Proc. Natl. Acad. Sci. U. S. A. 99 2002 6386 6391
71. A. Gartner, D.G. Polnau, V. Staiger, C. Sciarretta, L. Minichiello, H. Thoenen, T. Bonhoeffer, and M. Korte Hippocampal long-term potentiation is supported by presynaptic and postsynaptic tyrosine receptor kinase B-mediated phospholipase C gamma signaling 1 J.Neurosci. 26 2006 3496 3504
72. C. Gomes, R. Ferreira, J. George, R. Sanches, D.I. Rodrigues, N. Goncalves, and R.A. Cunha Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia J. Neuroinflamm. 10 2013 16
73. L.J. Goodman, J. Valverde, F. Lim, M.D. Geschwind, H.J. Federoff, A.I. Geller, and F. Hefti Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons Mol. Cell Neurosci. 7 1996 222 238
74. K. Gottmann, T. Mittmann, and V. Lessmann BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses Exp. Brain Res. 199 2009 203 234
75. G.S. Griesbach, D.A. Hovda, and F. Gomez-Pinilla Exercise-induced improvement in cognitive performance after traumatic brain injury in rats is dependent on BDNF activation Brain Res. 1288 2009 105 115
76. O. Griesbeck, M. Canossa, G. Campana, A. Gartner, M.C. Hoener, H. Nawa, R. Kolbeck, and H. Thoenen Are there differences between the secretion characteristics of NGF and BDNF? Implications for the modulatory role of neurotrophins in activity-dependent neuronal plasticity Microsc. Res. Tech. 45 1999 262 275
77. H. Hagena, and D. Manahan-Vaughan Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats contributes to the induction of persistent LTD via an adenosine-A1 receptor-regulated mechanism Cereb. Cortex 20 2010 1121 1130
78. J.G. Hanley Endosomal sorting of AMPA receptors in hippocampal neurons Biochem. Soc. Trans. 38 2010 460 465
79. M. Hartmann, R. Heumann, and V. Lessmann Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses EMBO J. 20 2001 5887 5897
80. W. Haubensak, F. Narz, R. Heumann, and V. Lessmann BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons 1 J. Cell Sci. 111 Pt 11 1998 1483 1493
81. T. Hochstrasser, D. Ehrlich, B. Sperner-Unterweger, and C. Humpel Antidepressants and anti-inflammatory drugs differentially reduce the release of NGF and BDNF from rat platelets 1 Pharmacopsychiatry 46 2013 29 34
82. M. Hofer, S.R. Pagliusi, A. Hohn, J. Leibrock, and Y.A. Barde Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain EMBO J. 9 1990 2459 2464
83. L. Hou, Y. Liu, X. Wang, H. Ma, J. He, Y. Zhang, C. Yu, W. Guan, and Y. Ma The effects of amyloid-beta42 oligomer on the proliferation and activation of astrocytes in vitro In Vitro Cell Dev. Biol. Anim. 47 2011 573 580
84. H.Y. Hsieh, C.L. Robertson, A. Vermehren-Schmaedick, and A. Balkowiec Nitric oxide regulates BDNF release from nodose ganglion neurons in a pattern-dependent and cGMP-independent manner J. Neurosci. Res. 88 2010 1285 1297
85. E.P. Huang Synaptic plasticity: going through phases with LTP Curr. Biol. 8 1998 R350 R352
86. Y.Y. Huang, and E.R. Kandel Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization Learn Mem. 1 1994 74 82
87. Y.Z. Huang, E. Pan, Z.Q. Xiong, and J.O. McNamara Zinc-mediated transactivation of TrkB potentiates the hippocampal mossy fiber-CA3 pyramid synapse Neuron 57 2008 546 558
88. J.R. Huie, S.M. Garraway, K.M. Baumbauer, K.C. Hoy Jr., B.S. Beas, K.S. Montgomery, J.L. Bizon, and J.W. Grau Brain-derived neurotrophic factor promotes adaptive plasticity within the spinal cord and mediates the beneficial effects of controllable stimulation Neuroscience 200 2012 74 90
89. G.W. Huntley, D.L. Benson, E.G. Jones, and P.J. Isackson Developmental expression of brain derived neurotrophic factor mRNA by neurons of fetal and adult monkey prefrontal cortex Brain Res. Dev. Brain Res. 70 1992 53 63
90. A.J. Hutchinson, C.L. Chou, D.D. Israel, W. Xu, and J.W. Regan Activation of EP2 prostanoid receptors in human glial cell lines stimulates the secretion of BDNF Neurochem. Int. 54 2009 439 446
91. B.R. Ickes, T.M. Pham, L.A. Sanders, D.S. Albeck, A.H. Mohammed, and A.C. Granholm Long-term environmental enrichment leads to regional increases in neurotrophin levels in rat brain Exp. Neurol. 164 2000 45 52
92. T. Inagaki, T. Begum, F. Reza, S. Horibe, M. Inaba, Y. Yoshimura, and Y. Komatsu Brain-derived neurotrophic factor-mediated retrograde signaling required for the induction of long-term potentiation at inhibitory synapses of visual cortical pyramidal neurons Neurosci. Res. 61 2008 192 200
93. C. Itami, F. Kimura, T. Kohno, M. Matsuoka, M. Ichikawa, T. Tsumoto, and S. Nakamura Brain-derived neurotrophic factor-Dependent unmasking of silent synapses in the developing mouse barrel cortex Proc. Natl. Acad. Sci. U. S. A. 100 2003 13069 13074
94. S.K. Jakawich, H.B. Nasser, M.J. Strong, A.J. McCartney, A.S. Perez, N. Rakesh, C.J. Carruthers, and M.A. Sutton Local presynaptic activity gates homeostatic changes in presynaptic function driven by dendritic BDNF synthesis Neuron 68 2010 1143 1158
95. Y.Y. Jean, L.D. Lercher, and C.F. Dreyfus Glutamate elicits release of BDNF from basal forebrain astrocytes in a process dependent on metabotropic receptors and the PLC pathway Neuron Glia Biol. 4 2008 35 42
96. S.J. Jeon, S.Y. Rhee, J.H. Ryu, J.H. Cheong, K. Kwon, S.I. Yang, S.H. Park, J. Lee, H.Y. Kim, S.H. Han, K.H. Ko, and C.Y. Shin Activation of adenosine A2A receptor up-regulates BDNF expression in rat primary cortical neurons Neurochem. Res. 36 2011 2259 2269
97. Y. Jia, C.M. Gall, and G. Lynch Presynaptic BDNF promotes postsynaptic long-term potentiation in the dorsal striatum J. Neurosci. 30 2010 14440 14445
98. S.Y. Jung, J. Kim, O.B. Kwon, J.H. Jung, K. An, A.Y. Jeong, C.J. Lee, Y.B. Choi, C.H. Bailey, E.R. Kandel, and J.H. Kim Input-specific synaptic plasticity in the amygdala is regulated by neuroligin-1 via postsynaptic NMDA receptors Proc. Natl. Acad. Sci. U. S. A. 107 2010 4710 4715
99. H. Kang, A.A. Welcher, D. Shelton, and E.M. Schuman Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation Neuron 19 1997 653 664
100. R.J. Kelleher III, A. Govindarajan, and S. Tonegawa Translational regulatory mechanisms in persistent forms of synaptic plasticity Neuron 44 2004 59 73
101. B.J. Kerr, E.J. Bradbury, D.L. Bennett, P.M. Trivedi, P. Dassan, J. French, D.B. Shelton, S.B. McMahon, and S.W. Thompson Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord J. Neurosci. 19 1999 5138 5148
102. D.H. Kim, J.M. Kim, S.J. Park, M. Cai, X. Liu, S. Lee, C.Y. Shin, and J.H. Ryu GABA(A) receptor blockade enhances memory consolidation by increasing hippocampal BDNF levels Neuropsychopharmacology 37 2012 422 433
103. K. Klein, A. Aeschlimann, S. Jordan, R. Gay, S. Gay, and H. Sprott ATP induced brain-derived neurotrophic factor expression and release from osteoarthritis synovial fibroblasts is mediated by purinergic receptor P2X4 PLoS One 7 2012 e36693
104. K. Kohara, A. Kitamura, M. Morishima, and T. Tsumoto Activity-dependent transfer of brain-derived neurotrophic factor to postsynaptic neurons Science 291 2001 2419 2423
105. K. Kohara, H. Yasuda, Y. Huang, N. Adachi, K. Sohya, and T. Tsumoto A local reduction in cortical GABAergic synapses after a loss of endogenous brain-derived neurotrophic factor, as revealed by single-cell gene knock-out method J. Neurosci. 27 2007 7234 7244
106. M. Kojima, N. Takei, T. Numakawa, Y. Ishikawa, S. Suzuki, T. Matsumoto, R. Katoh-Semba, H. Nawa, and H. Hatanaka Biological characterization and optical imaging of brain-derived neurotrophic factor-green fluorescent protein suggest an activity-dependent local release of brain-derived neurotrophic factor in neurites of cultured hippocampal neurons J. Neurosci. Res. 64 2001 1 10
107. M. Kokaia, I. Ferencz, G. Leanza, E. Elmer, M. Metsis, Z. Kokaia, R.G. Wiley, and O. Lindvall Immunolesioning of basal forebrain cholinergic neurons facilitates hippocampal kindling and perturbs neurotrophin messenger RNA regulation Neuroscience 70 1996 313 327
108. R. Kolarow, T. Brigadski, and V. Lessmann Postsynaptic secretion of BDNF and NT-3 from hippocampal neurons depends on calcium calmodulin kinase II signaling and proceeds via delayed fusion pore opening J. Neurosci. 27 2007 10350 10364
109. M. Korte, P. Carroll, E. Wolf, G. Brem, H. Thoenen, and T. Bonhoeffer Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor 16 Proc. Natl. Acad. Sci. U. S. A. 92 1995 8856 8860
110. M. Korte, O. Griesbeck, C. Gravel, P. Carroll, V. Staiger, H. Thoenen, and T. Bonhoeffer Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice Proc. Natl. Acad. Sci. U. S. A. 93 1996 12547 12552
111. M. Korte, H. Kang, T. Bonhoeffer, and E. Schuman A role for BDNF in the late-phase of hippocampal long-term potentiation Neuropharmacology 37 1998 553 559
112. A.H. Kossel, S.B. Cambridge, U. Wagner, and T. Bonhoeffer A caged Ab reveals an immediate/instructive effect of BDNF during hippocampal synaptic potentiation Proc. Natl. Acad. Sci. U. S. A. 98 2001 14702 14707
113. N. Kuczewski, C. Porcher, N. Ferrand, H. Fiorentino, C. Pellegrino, R. Kolarow, V. Lessmann, I. Medina, and J.L. Gaiarsa Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity J. Neurosci. 28 2008 7013 7023
114. N. Kuczewski, C. Porcher, V. Lessmann, I. Medina, and J.L. Gaiarsa Back-propagating action potential: a key contributor in activity-dependent dendritic release of BDNF Commun. Integr. Biol. 1 2008 153 155
115. N. Kuczewski, C. Fuchs, N. Ferrand, J.N. Jovanovic, J.L. Gaiarsa, and C. Porcher Mechanism of GABAB receptor-induced BDNF secretion and promotion of GABAA receptor membrane expression J. Neurochem. 118 2011 533 545
116. K.O. Lai, A.S. Wong, M.C. Cheung, P. Xu, Z. Liang, K.C. Lok, H. Xie, M.E. Palko, W.H. Yung, L. Tessarollo, Z.H. Cheung, and N.Y. Ip TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory Nat. Neurosci. 15 2012 1506 1515
117. A.G. Lau, H.A. Irier, J. Gu, D. Tian, L. Ku, G. Liu, M. Xia, B. Fritsch, J.Q. Zheng, R. Dingledine, B. Xu, B. Lu, and Y. Feng Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF) Proc. Natl. Acad. Sci. U. S. A. 107 2010 15945 15950
118. A.M. Lee, B.R. Kanter, D. Wang, J.P. Lim, M.E. Zou, C. Qiu, T. McMahon, J. Dadgar, S.C. Fischbach-Weiss, and R.O. Messing Prkcz null mice show normal learning and memory Nature 493 2013 416 419
119. V. Lessmann, and T. Brigadski Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update Neurosci. Res. 65 2009 11 22
120. V. Lessmann, K. Gottmann, and M. Malcangio Neurotrophin secretion: current facts and future prospects Prog. Neurobiol. 69 2003 341 374
121. I.J. Lever, E.J. Bradbury, J.R. Cunningham, D.W. Adelson, M.G. Jones, S.B. McMahon, J.C. Marvizon, and M. Malcangio Brain-derived neurotrophic factor is released in the dorsal horn by distinctive patterns of afferent fiber stimulation J. Neurosci. 21 2001 4469 4477
122. E.S. Levine, C.F. Dreyfus, I.B. Black, and M.R. Plummer Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors Proc. Natl. Acad. Sci. U. S. A. 92 1995 8074 8077
123. 2+ elevations in CA3 pyramidal neurons J. Neurophysiol. 103 2010 2846 2856
124. C. Li, J. Dabrowska, R. Hazra, and D.G. Rainnie Synergistic activation of dopamine D1 and TrkB receptors mediate gain control of synaptic plasticity in the basolateral amygdala PLoS One 6 2011 e26065
125. J. Liang, X. Zheng, J. Chen, Y. Li, X. Xing, Y. Bai, and Y. Li Roles of BDNF, dopamine D(3) receptors, and their interactions in the expression of morphine-induced context-specific locomotor sensitization Eur. Neuropsychopharmacol. 21 2011 825 834
126. G.Y. Liao, J.J. An, K. Gharami, E.G. Waterhouse, F. Vanevski, K.R. Jones, and B. Xu Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin Nat. Med. 18 2012 564 571
127. Y.T. Lin, L.S. Ro, H.L. Wang, and J.C. Chen Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study J. Neuroinflammation 8 2011 126
128. J.E. Lochner, E. Spangler, M. Chavarha, C. Jacobs, K. McAllister, L.C. Schuttner, and B.A. Scalettar Efficient copackaging and cotransport yields postsynaptic colocalization of neuromodulators associated with synaptic plasticity Dev. Neurobiol. 68 2008 1243 1256
129. H. Lou, S.K. Kim, E. Zaitsev, C.R. Snell, B. Lu, and Y.P. Loh Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e Neuron 45 2005 245 255
130. Y. Lu, K. Christian, and B. Lu BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory? Neurobiol. Learn Mem. 89 2008 312 323
131. H. Lu, P.L. Cheng, B.K. Lim, N. Khoshnevisrad, and M.M. Poo Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition Neuron 67 2010 821 833
132. Y. Lu, Y. Ji, S. Ganesan, R. Schloesser, K. Martinowich, M. Sun, F. Mei, M.V. Chao, and B. Lu TrkB as a potential synaptic and behavioral tag J. Neurosci. 31 2011 11762 11771
133. X.G. Luo, R.A. Rush, and X.F. Zhou Ultrastructural localization of brain-derived neurotrophic factor in rat primary sensory neurons Neurosci. Res. 39 2001 377 384
134. L. Ma, D.D. Wang, T.Y. Zhang, H. Yu, Y. Wang, S.H. Huang, F.S. Lee, and Z.Y. Chen Region-specific involvement of BDNF secretion and synthesis in conditioned taste aversion memory formation J. Neurosci. 31 2011 2079 2090
135. B. Ma, J.N. Savas, M.V. Chao, and N. Tanese Quantitative analysis of BDNF/TrkB protein and mRNA in cortical and striatal neurons using alpha-tubulin as a normalization factor Cytometry A 81 2012 704 717
136. J.C. Madara, and E.S. Levine Presynaptic and postsynaptic NMDA receptors mediate distinct effects of brain-derived neurotrophic factor on synaptic transmission J. Neurophysiol. 100 2008 3175 3184
137. J.P. Magby, C. Bi, Z.Y. Chen, F.S. Lee, and M.R. Plummer Single-cell characterization of retrograde signaling by brain-derived neurotrophic factor J. Neurosci. 26 2006 13531 13536
138. R.C. Malenka, and M.F. Bear LTP and LTD: an embarrassment of riches Neuron 44 2004 5 21
139. H. Markram, W. Gerstner, and P.J. Sjostrom A history of spike-timing-dependent plasticity Front Synaptic Neurosci. 3 2011 4
140. H. Markram, W. Gerstner, and P.J. Sjostrom Spike-timing-dependent plasticity: a comprehensive overview Front Synaptic Neurosci. 4 2012 2
141. N. Matsuda, H. Lu, Y. Fukata, J. Noritake, H. Gao, S. Mukherjee, T. Nemoto, M. Fukata, and M.M. Poo Differential activity-dependent secretion of brain-derived neurotrophic factor from axon and dendrite J. Neurosci. 29 2009 14185 14198
142. T. Matsumoto, S. Rauskolb, M. Polack, J. Klose, R. Kolbeck, M. Korte, and Y.A. Barde Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF Nat. Neurosci. 11 2008 131 133
143. F. Mei, G. Nagappan, Y. Ke, T.C. Sacktor, and B. Lu BDNF facilitates L-LTP maintenance in the absence of protein synthesis through PKMzeta PLoS One 6 2011 e21568
144. S. Meis, T. Endres, and V. Lessmann Postsynaptic BDNF signalling regulates long-term potentiation at thalamo-amygdala afferents J. Physiol. 590 2012 193 208
145. G.J. Michael, S. Averill, A. Nitkunan, M. Rattray, D.L. Bennett, Q. Yan, and J.V. Priestley Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord J. Neurosci. 17 1997 8476 8490
146. H. Miladi-Gorji, A. Rashidy-Pour, Y. Fathollahi, M.M. Akhavan, S. Semnanian, and M. Safari Voluntary exercise ameliorates cognitive deficits in morphine dependent rats: the role of hippocampal brain-derived neurotrophic factor Neurobiol. Learn Mem. 96 2011 479 491
147. L. Minichiello, A.M. Calella, D.L. Medina, T. Bonhoeffer, R. Klein, and M. Korte Mechanism of TrkB-mediated hippocampal long-term potentiation Neuron 36 2002 121 137
148. M.H. Mohajerani, S. Sivakumaran, P. Zacchi, P. Aguilera, and E. Cherubini Correlated network activity enhances synaptic efficacy via BDNF and the ERK pathway at immature CA3 CA1 connections in the hippocampus Proc. Natl. Acad. Sci. U. S. A. 104 2007 13176 13181
149. Y. Mu, and M.M. Poo Spike timing-dependent LTP/LTD mediates visual experience-dependent plasticity in a developing retinotectal system Neuron 50 2006 115 125
150. J.B. Munson, D.L. Shelton, and S.B. McMahon Adult mammalian sensory and motor neurons: roles of endogenous neurotrophins and rescue by exogenous neurotrophins after axotomy J. Neurosci. 17 1997 470 476
151. G. Nagappan, E. Zaitsev, V.V. Senatorov Jr., J. Yang, B.L. Hempstead, and
152. K. Nakajima, Y. Tohyama, S. Kohsaka, and T. Kurihara Ceramide activates microglia to enhance the production/secretion of brain-derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro 28 J. Neurochem. 80 2002 697 705
153. T. Nakajima, M. Sato, N. Akaza, and Y. Umezawa Cell-based fluorescent indicator to visualize brain-derived neurotrophic factor secreted from living neurons ACS Chem. Biol. 3 2008 352 358
154. S. Navakkode, and M. Korte Cooperation between cholinergic and glutamatergic receptors are essential to induce BDNF-dependent long-lasting memory storage Hippocampus 22 2012 335 346
155. R.A. Nicoll, and D. Schmitz Synaptic plasticity at hippocampal mossy fibre synapses Nat. Rev. Neurosci. 6 2005 863 876
156. O. Noga, C. Englmann, G. Hanf, A. Grutzkau, J. Seybold, and G. Kunkel The production, storage and release of the neurotrophins nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 by human peripheral eosinophils in allergics and non-allergics Clin. Exp. Allergy 33 2003 649 654
157. L.C. Ou, and P.W. Gean Regulation of amygdala-dependent learning by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol-3-kinase Neuropsychopharmacology 31 2006 287 296
158. L.C. Ou, S.H. Yeh, and P.W. Gean Late expression of brain-derived neurotrophic factor in the amygdala is required for persistence of fear memory Neurobiol. Learn Mem. 93 2010 372 382
159. P.T. Pang, and B. Lu Regulation of late-phase LTP and long-term memory in normal and aging hippocampus: role of secreted proteins tPA and BDNF Ageing Res. Rev. 3 2004 407 430
160. P.T. Pang, H.K. Teng, E. Zaitsev, N.T. Woo, K. Sakata, S. Zhen, K.K. Teng, W.H. Yung, B.L. Hempstead, and B. Lu Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity Science 306 2004 487 491
161. H. Park, and M.M. Poo Neurotrophin regulation of neural circuit development and function Nat. Rev. Neurosci. 14 2013 7 23
162. S.L. Patterson, L.M. Grover, P.A. Schwartzkroin, and M. Bothwell Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs Neuron 9 1992 1081 1088
163. S.L. Patterson, T. Abel, T.A. Deuel, K.C. Martin, J.C. Rose, and E.R. Kandel Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice Neuron 16 1996 1137 1145
164. S.L. Patterson, C. Pittenger, A. Morozov, K.C. Martin, H. Scanlin, C. Drake, and E.R. Kandel Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase Neuron 32 2001 123 140
165. S.S. Pattwell, K.G. Bath, R. Perez-Castro, F.S. Lee, M.V. Chao, and I. Ninan The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex J. Neurosci. 32 2012 2410 2421
166. O. Paulsen, and T.J. Sejnowski Natural patterns of activity and long-term synaptic plasticity Curr. Opin. Neurobiol. 10 2000 172 179
167. V. Pawlak, and J.N. Kerr Dopamine receptor activation is required for corticostriatal spike-timing-dependent plasticity J. Neurosci. 28 2008 2435 2446
168. S. Pezet, M. Malcangio, I.J. Lever, M.S. Perkinton, S.W. Thompson, R.J. Williams, and S.B. McMahon Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn Mol. Cell Neurosci. 21 2002 684 695
169. H.S. Phillips, J.M. Hains, G.R. Laramee, A. Rosenthal, and J.W. Winslow Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons Science 250 1990 290 294
170. L.D. Pozzo-Miller, W. Gottschalk, L. Zhang, K. McDermott, J. Du, R. Gopalakrishnan, C. Oho, Z.H. Sheng, and B. Lu Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice J. Neurosci. 19 1999 4972 4983
171. S.J. Rabin, A. Bachis, and I. Mocchetti Gangliosides activate Trk receptors by inducing the release of neurotrophins J. Biol. Chem. 277 2002 49466 49472
172. B. Ramachandran, and J.U. Frey Interfering with the actin network and its effect on long-term potentiation and synaptic tagging in hippocampal CA1 neurons in slices in vitro J. Neurosci. 29 2009 12167 12173
173. N. Rebola, M. Carta, F. Lanore, C. Blanchet, and C. Mulle NMDA receptor-dependent metaplasticity at hippocampal mossy fiber synapses Nat. Neurosci. 14 2011 691 693
174. R.L. Redondo, and R.G. Morris Making memories last: the synaptic tagging and capture hypothesis Nat. Rev. Neurosci. 12 2011 17 30
175. R.L. Redondo, H. Okuno, P.A. Spooner, B.G. Frenguelli, H. Bito, and R.G. Morris Synaptic tagging and capture: differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation J. Neurosci. 30 2010 4981 4989
176. M. Righi, E. Tongiorgi, and A. Cattaneo Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway J. Neurosci. 20 2000 3165 3174
177. H.B. Rind, R. Butowt, and C.S. von Bartheld Synaptic targeting of retrogradely transported trophic factors in motoneurons: comparison of glial cell line-derived neurotrophic factor, brain-derived neurotrophic factor, and cardiotrophin-1 with tetanus toxin J. Neurosci. 25 2005 539 549
178. C. Rosenmund, and C.F. Stevens Definition of the readily releasable pool of vesicles at hippocampal synapses Neuron 16 1996 1197 1207
179. A. Rozov, A.R. Zivkovic, and M.K. Schwarz Homer1 gene products orchestrate Ca(2+)-permeable AMPA receptor distribution and LTP expression Front Synaptic Neurosci. 4 2012 4
180. T.C. Sacktor Memory maintenance by PKMzeta - an evolutionary perspective Mol. Brain 5 2012 31
181. T. Sadakata, Y. Shinoda, M. Oka, Y. Sekine, Y. Sato, C. Saruta, H. Miwa, M. Tanaka, S. Itohara, and T. Furuichi Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF and causes autistic-like behavior in mice Proc. Natl. Acad. Sci. U. S. A. 109 2012 21104 21109
182. S. Sajikumar, and M. Korte Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase Mzeta (PKMzeta) Proc. Natl. Acad. Sci. U. S. A. 108 2011 2551 2556
183. S. Sajikumar, S. Navakkode, T.C. Sacktor, and J.U. Frey Synaptic tagging and cross-tagging: the role of protein kinase Mzeta in maintaining long-term potentiation but not long-term depression J. Neurosci. 25 2005 5750 5756
184. S. Sajikumar, Q. Li, W.C. Abraham, and Z.C. Xiao Priming of short-term potentiation and synaptic tagging/capture mechanisms by ryanodine receptor activation in rat hippocampal CA1 Learn Mem. 16 2009 178 186
185. K. Sakata, N.H. Woo, K. Martinowich, J.S. Greene, R.J. Schloesser, L. Shen, and B. Lu Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex Proc. Natl. Acad. Sci. U. S. A. 106 2009 5942 5947
186. C. Salio, S. Averill, J.V. Priestley, and A. Merighi Costorage of BDNF and neuropeptides within individual dense-core vesicles in central and peripheral neurons 5 Dev. Neurobiol. 67 2007 326 338
187. M. Sallert, T. Rantamaki, A. Vesikansa, H. Anthoni, K. Harju, J. Yli-Kauhaluoma, T. Taira, E. Castren, and S.E. Lauri Brain-derived neurotrophic factor controls activity-dependent maturation of CA1 synapses by downregulating tonic activation of presynaptic kainate receptors J. Neurosci. 29 2009 11294 11303
188. S. Santi, S. Cappello, M. Riccio, M. Bergami, G. Aicardi, U. Schenk, M. Matteoli, and M. Canossa Hippocampal neurons recycle BDNF for activity-dependent secretion and LTP maintenance EMBO J. 25 2006 4372 4380
189. B.A. Scalettar, C. Jacobs, A. Fulwiler, L. Prahl, A. Simon, L. Hilken, and J.E. Lochner Hindered submicron mobility and long-term storage of presynaptic dense-core granules revealed by single-particle tracking Dev. Neurobiol. 72 2012 1181 1195
190. S. Schildt, T. Endres, V. Lessmann, and E. Edelmann Acute and chronic interference with BDNF/TrkB signaling impair LTP selectively at mossy fiber synapses in the CA3 region of mouse hippocampus Neuropharmacology 71 2013 247 254
191. A.G. Schjetnan, and M.L. Escobar In vivo BDNF modulation of hippocampal mossy fiber plasticity induced by high frequency stimulation Hippocampus 22 2012 1 8
192. R. Schmidt-Kastner, C. Wetmore, and L. Olson Comparative study of brain-derived neurotrophic factor messenger RNA and protein at the cellular level suggests multiple roles in hippocampus, striatum and cortex Neuroscience 74 1996 161 183
193. B.S. Seebach, V. Arvanov, and L.M. Mendell Effects of BDNF and NT-3 on development of Ia/motoneuron functional connectivity in neonatal rats J. Neurophysiol. 81 1999 2398 2405
194. G.H. Seol, J. Ziburkus, S. Huang, L. Song, I.T. Kim, K. Takamiya, R.L. Huganir, H.K. Lee, and A. Kirkwood Neuromodulators control the polarity of spike-timing-dependent synaptic plasticity Neuron 55 2007 919 929
195. E. Sermasi, E. Margotti, A. Cattaneo, and L. Domenici Trk B signalling controls LTP but not LTD expression in the developing rat visual cortex Eur. J. Neurosci. 12 2000 1411 1419
196. D.L. Shelton, J. Sutherland, J. Gripp, T. Camerato, M.P. Armanini, H.S. Phillips, K. Carroll, S.D. Spencer, and A.D. Levinson Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins16 J. Neurosci. 15 1995 477 491
197. Y. Shinoda, T. Sadakata, K. Nakao, R. Katoh-Semba, E. Kinameri, A. Furuya, Y. Yanagawa, H. Hirase, and T. Furuichi Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network Proc. Natl. Acad. Sci. U. S. A. 108 2011 373 378
198. T. Sigurdsson, V. Doyere, C.K. Cain, and J.E. LeDoux Long-term potentiation in the amygdala: a cellular mechanism of fear learning and memory Neuropharmacology 52 2007 215 227
199. S. Sivakumaran, M.H. Mohajerani, and E. Cherubini At immature mossy-fiber-CA3 synapses, correlated presynaptic and postsynaptic activity persistently enhances GABA release and network excitability via BDNF and cAMP-dependent PKA J. Neurosci. 29 2009 2637 2647
200. V.A. Skucas, A.M. Duffy, L.C. Harte-Hargrove, A. Magagna-Poveda, T. Radman, G. Chakraborty, C.E. Schroeder, N.J. Maclusky, and H.E. Scharfman Testosterone depletion in adult male rats increases mossy fiber transmission, LTP, and sprouting in area CA3 of hippocampus J. Neurosci. 33 2013 2338 2355
201. S.E. Slack, and S.W. Thompson Brain-derived neurotrophic factor induces NMDA receptor 1 phosphorylation in rat spinal cord Neuroreport 13 2002 1967 1970
202. S.E. Slack, S. Pezet, S.B. McMahon, S.W. Thompson, and M. Malcangio Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord 2 Eur. J. Neurosci. 20 2004 1769 1778
203. M.A. Smith, S. Makino, R. Kvetnansky, and R.M. Post Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus J. Neurosci. 15 1995 1768 1777
204. M.A. Smith, L.X. Zhang, W.E. Lyons, and L.A. Mamounas Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers Neuroreport 8 1997 1829 1834
205. J.H. Son, and U.H. Winzer-Serhan Chronic neonatal nicotine exposure increases mRNA expression of neurotrophic factors in the postnatal rat hippocampus Brain Res. 1278 2009 1 14
206. J. Soule, E. Messaoudi, and C.R. Bramham Brain-derived neurotrophic factor and control of synaptic consolidation in the adult brain Biochem. Soc. Trans. 34 2006 600 604
207. P. Stoll, A. Plessow, K. Bratke, J.C. Virchow, and M. Lommatzsch Differential effect of clopidogrel and aspirin on the release of BDNF from platelets2 J. Neuroimmunol 238 2011 104 106
208. C. Su, R.L. Cunningham, N. Rybalchenko, and M. Singh Progesterone increases the release of brain-derived neurotrophic factor from glia via progesterone receptor membrane component 1 (Pgrmc1)-dependent ERK5 signaling Endocrinology 153 2012 4389 4400
209. C.C. Swanwick, M.B. Harrison, and J. Kapur Synaptic and extrasynaptic localization of brain-derived neurotrophic factor and the tyrosine kinase B receptor in cultured hippocampal neurons J. Comp. Neurol. 478 2004 405 417
210. S. Tamura, H. Suzuki, Y. Hirowatari, M. Hatase, A. Nagasawa, K. Matsuno, S. Kobayashi, and T. Moriyama Release reaction of brain-derived neurotrophic factor (BDNF) through PAR1 activation and its two distinct pools in human platelets 3 Thromb. Res. 128 2011 e55 e61
211. J. Tanaka, Y. Horiike, M. Matsuzaki, T. Miyazaki, G.C. Ellis-Davies, and H. Kasai Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines Science 319 2008 1683 1687
212. T. Timmusk, K. Palm, M. Metsis, T. Reintam, V. Paalme, M. Saarma, and H. Persson Multiple promoters direct tissue-specific expression of the rat BDNF gene Neuron 10 1993 475 489
213. E. Tongiorgi Activity-dependent expression of brain-derived neurotrophic factor in dendrites: facts and open questions Neurosci. Res. 61 2008 335 346
214. E. Tongiorgi, M. Righi, and A. Cattaneo Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons J. Neurosci. 17 1997 9492 9505
215. E. Tongiorgi, M. Armellin, P.G. Giulianini, G. Bregola, S. Zucchini, B. Paradiso, O. Steward, A. Cattaneo, and M. Simonato Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis J. Neurosci. 24 2004 6842 6852
216. E. Tongiorgi, L. Domenici, and M. Simonato What is the biological significance of BDNF mRNA targeting in the dendrites? Clues from epilepsy and cortical development Mol. Neurobiol. 33 2006 17 32
217. T. Trang, S. Beggs, X. Wan, and M.W. Salter P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation5 J. Neurosci. 29 2009 3518 3528
218. W.J. Tyler, X.L. Zhang, K. Hartman, J. Winterer, W. Muller, P.K. Stanton, and L. Pozzo-Miller BDNF increases release probability and the size of a rapidly recycling vesicle pool within rat hippocampal excitatory synapses J. Physiol. 574 2006 787 803
219. S. Vaynman, Z. Ying, and F. Gomez-Pinilla Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition Eur. J. Neurosci. 20 2004 2580 2590
220. D. Vazquez-Sanroman, C. Sanchis-Segura, R. Toledo, M.E. Hernandez, J. Manzo, and M. Miquel The effects of enriched environment on BDNF expression in the mouse cerebellum depending on the length of exposure Behav. Brain Res. 243C 2013 118 128
221. C. Verderio, F. Bianco, M.P. Blanchard, M. Bergami, M. Canossa, E. Scarfone, and M. Matteoli Cross talk between vestibular neurons and Schwann cells mediates BDNF release and neuronal regeneration Brain Cell Biol. 35 2006 187 201
222. A. Villers, E. Godaux, and L. Ris Long-lasting LTP requires neither repeated trains for its induction nor protein synthesis for its development PLoS One 7 2012 e40823
223. L.J. Volk, J.L. Bachman, R. Johnson, Y. Yu, and R.L. Huganir PKM-zeta is not required for hippocampal synaptic plasticity, learning and memory Nature 493 2013 420 423
224. C.S. von Bartheld, X. Wang, and R. Butowt Anterograde axonal transport, transcytosis, and recycling of neurotrophic factors: the concept of trophic currencies in neural networks Mol. Neurobiol. 24 2001 1 28
225. C. Walz, K. Jungling, V. Lessmann, and K. Gottmann Presynaptic plasticity in an immature neocortical network requires NMDA receptor activation and BDNF release J. Neurophysiol. 96 2006 3512 3516
226. H. Wang, N. Ward, M. Boswell, and D.M. Katz Secretion of brain-derived neurotrophic factor from brain microvascular endothelial cells Eur.J.Neurosci. 23 2006 1665 1670
227. A. Warnecke, S. Sasse, G.I. Wenzel, A. Hoffmann, G. Gross, G. Paasche, V. Scheper, U. Reich, K.H. Esser, T. Lenarz, T. Stover, and K. Wissel Stable release of BDNF from the fibroblast cell line NIH3T3 grown on silicone elastomers enhances survival of spiral ganglion cells in vitro and in vivo Hear Res. 289 2012 86 97
228. K. Watanabe, E. Hashimoto, W. Ukai, T. Ishii, T. Yoshinaga, T. Ono, M. Tateno, I. Watanabe, T. Shirasaka, S. Saito, and T. Saito Effect of antidepressants on brain-derived neurotrophic factor (BDNF) release from platelets in the rats 10 Prog. Neuropsychopharmacol. Biol. Psychiatry 34 2010 1450 1454
229. E.G. Waterhouse, J.J. An, L.L. Orefice, M. Baydyuk, G.Y. Liao, K. Zheng, B. Lu, and B. Xu BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission J. Neurosci. 32 2012 14318 14330
230. C. Wetmore, P. Ernfors, H. Persson, and L. Olson Localization of brain-derived neurotrophic factor mRNA to neurons in the brain by in situ hybridization Exp. Neurol. 109 1990 141 152
231. C. Wetmore, Y.H. Cao, R.F. Pettersson, and L. Olson Brain-derived neurotrophic factor: subcellular compartmentalization and interneuronal transfer as visualized with anti-peptide antibodies Proc. Natl. Acad. Sci. U. S. A. 88 1991 9843 9847
232. C. Wetmore, L. Olson, and A.J. Bean Regulation of brain-derived neurotrophic factor (BDNF) expression and release from hippocampal neurons is mediated by non-NMDA type glutamate receptors J. Neurosci. 14 1994 1688 1700
233. Y.J. Wu, A. Kruttgen, J.C. Moller, D. Shine, J.R. Chan, E.M. Shooter, and J.M. Cosgaya Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 are sorted to dense-core vesicles and released via the regulated pathway in primary rat cortical neurons J. Neurosci. Res. 75 2004 825 834
234. L.L. Wu, Y. Fan, S. Li, X.J. Li, and X.F. Zhou Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release J. Biol. Chem. 285 2010 5614 5623
235. X. Xia, V. Lessmann, and T.F. Martin Imaging of evoked dense-core-vesicle exocytosis in hippocampal neurons reveals long latencies and kiss-and-run fusion events J. Cell Sci. 122 2009 75 82
236. B. Xu, W. Gottschalk, A. Chow, R.I. Wilson, E. Schnell, K. Zang, D. Wang, R.A. Nicoll, B. Lu, and L.F. Reichardt The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB J. Neurosci. 20 2000 6888 6897
237. Z.Q. Xu, Y. Sun, H.Y. Li, Y. Lim, J.H. Zhong, and X.F. Zhou Endogenous proBDNF is a negative regulator of migration of cerebellar granule cells in neonatal mice Eur. J. Neurosci. 33 2011 1376 1384
238. Q. Yan, R.D. Rosenfeld, C.R. Matheson, N. Hawkins, O.T. Lopez, L. Bennett, and A.A. Welcher Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system Neuroscience 78 1997 431 448
239. F. Yang, H.S. Je, Y. Ji, G. Nagappan, B. Hempstead, and B. Lu Pro-BDNF-induced synaptic depression and retraction at developing neuromuscular synapses J. Cell Biol. 185 2009 727 741
240. J. Yang, C.J. Siao, G. Nagappan, T. Marinic, D. Jing, K. McGrath, Z.Y. Chen, W. Mark, L. Tessarollo, F.S. Lee, B. Lu, and B.L. Hempstead Neuronal release of proBDNF Nat. Neurosci. 12 2009 113 115
241. Z. Ying, R.R. Roy, H. Zhong, S. Zdunowski, V.R. Edgerton, and F. Gomez-Pinilla BDNF-exercise interactions in the recovery of symmetrical stepping after a cervical hemisection in rats Neuroscience 155 2008 1070 1078
242. A. Yoshii, and M. Constantine-Paton Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease Dev. Neurobiol. 70 2010 304 322
243. S.S. Zakharenko, S.L. Patterson, I. Dragatsis, S.O. Zeitlin, S.A. Siegelbaum, E.R. Kandel, and A. Morozov Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses Neuron 39 2003 975 990
244. J.C. Zhang, P.M. Lau, and G.Q. Bi Gain in sensitivity and loss in temporal contrast of STDP by dopaminergic modulation at hippocampal synapses Proc. Natl. Acad. Sci. U. S. A. 106 2009 13028 13033
245. F. Zhang, Y.F. Lu, Q. Wu, J. Liu, and J.S. Shi Resveratrol promotes neurotrophic factor release from astroglia Exp. Biol. Med. (Maywood) 237 2012 943 948