At immature mossy-fiber-CA3 synapses, correlated Presynaptic and postsynaptic activity persistently enhances GABA release and network excitability via BDNF and cAMP-dependent PKA

Journal of Neuroscience

Volumn 29, Issue 8, 2009, Pages 2637-2647

  Sivakumaran, Sudhir ^a   Mohajerani, Majid H ^a,b   Cherubini, Enrico ^a  

^a SISSA   (Italy)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

BDNF; CAMP dependent PKA; Excitatory action of GABA; Hippocampal mossy fibres; Increased synaptic efficacy; Spike timing dependent plasticity

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; PRESYNAPTIC RECEPTOR; VOLTAGE GATED CALCIUM CHANNEL;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL MATURATION; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; GRANULE CELL; LEARNING; LONG TERM POTENTIATION; MOSSY FIBER; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NEWBORN; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; SPIKE WAVE;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; BRAIN-DERIVED NEUROTROPHIC FACTOR; BUMETANIDE; CALCIUM; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTRIC STIMULATION; ENZYME INHIBITORS; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; MOSSY FIBERS, HIPPOCAMPAL; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; SODIUM POTASSIUM CHLORIDE SYMPORTER INHIBITORS; SYNAPSES; SYNAPTIC POTENTIALS; SYNAPTIC TRANSMISSION; TIME FACTORS;

EID: 61449148442     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5019-08.2009     Document Type: Article

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