Release reaction of brain-derived neurotrophic factor (BDNF) through PAR1 activation and its two distinct pools in human platelets

Thrombosis Research

Volumn 128, Issue 5, 2011, Pages

  Tamura, Shogo ^a,b   Suzuki, Hidenori ^c   Hirowatari, Yuji ^d   Hatase, Masanao ^e   Nagasawa, Ayumi ^a   Matsuno, Kazuhiko ^e   Kobayashi, Seiichi ^a   Moriyama, Takanori ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d TOSOH CORPORATION   (Japan)

^e HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

Author keywords

BDNF; immunoelectron microscopy; PAR1; platelet; thrombin

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; ENDOSTATIN; PROSTAGLANDIN E1; PROTEINASE ACTIVATED RECEPTOR 1; SEROTONIN; THROMBIN; VASCULOTROPIN;

ARTICLE; CELLULAR DISTRIBUTION; CYTOPLASM; DENSITY GRADIENT CENTRIFUGATION; HUMAN; HUMAN CELL; IMMUNOELECTRON MICROSCOPY; IN VITRO STUDY; LYSOSOME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; SEROTONIN RELEASE; THROMBOCYTE; THROMBOCYTE ACTIVATION;

BLOOD PLATELETS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CYTOPLASM; CYTOPLASMIC GRANULES; HUMANS; PLATELET ACTIVATION; RECEPTOR, PAR-1;

EID: 80055096002     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.06.002     Document Type: Article

References (44)

1. Y.A. Barde, D. Edgar, and H. Thoenen Purification of a new neurotrophic factor from mammalian brain EMBO J 1 1982 549 553
2. J. Leibrock, F. Lottspeich, A. Hohn, M. Hofer, B. Hengerer, and P. Masiakowski Molecular cloning and expression of brain-derived neurotrophic factor Nature 341 1989 149 152 (Pubitemid 19222776)
3. M. Bibel, and Y.A. Barde Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system Genes Dev 14 2000 2919 2937
4. D. Dawbarn, and S.J. Allen Neurotrophins and neurodegeneration Neuropathol Appl Neurobiol 29 2003 211 230 (Pubitemid 36718170)
5. J. Soule, E. Messaoudi, and C.R. Bramham Brain-derived neurotrophic factor and control of synaptic consolidation in the adult brain Biochem Soc Trans 34 2006 600 604 (Pubitemid 44230773)
6. P. Casaccia-Bonnefil, C. Gu, G. Khursigara, and M.V. Chao p75 neurotrophin receptor as a modulator of survival and death decisions Microsc Res Tech 45 1999 217 224 (Pubitemid 29264985)
7. N. Durany, T. Michel, J. Kurt, F.F. Cruz-Sanchez, J. Cervas-Navarro, and P. Riederer Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains Int J Dev Neurosci 18 2000 807 813 (Pubitemid 32037055)
8. M.E. Kozisek, D. Middlemas, and D.B. Bylund Brain-derived neurotrophic factor and its receptor tropomyosin-related kinase B in the mechanism of action of antidepressant therapies Pharmacol Ther 117 2008 30 51 (Pubitemid 350192670)
9. L. Tapia-Arancibia, E. Aliaga, M. Silhol, and S. Arancibia New insights into brain BDNF function in normal aging and Alzheimer disease Brain Res Rev 59 2008 201 220
10. D.K. Binder, and H.E. Scharfman Brain-derived neurotrophic factor Growth Factors 22 2004 123 131 (Pubitemid 39377904)
11. B. Connor, and M. Dragunow The role of neuronal growth factors in neurodegenerative disorders of the human brain Brain Res Rev 27 1998 1 39 (Pubitemid 28300281)
12. P. Ernfors, C. Wetmore, L. Olson, and H. Persson Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family Neuron 5 1990 511 526 (Pubitemid 20369587)
13. R. Katoh-Semba, I.K. Takeuchi, R. Semba, and K. Kato Distribution of brain-derived neurotrophic factor in rats and its changes with development in the brain J Neurochem 69 1997 34 42 (Pubitemid 27274153)
14. P.C. Maisonpierre, L. Belluscio, B. Friedman, R.F. Alderson, S.J. Wiegand, and M.E. Furth NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression Neuron 5 1990 501 509 (Pubitemid 20369586)
15. P.C. Maisonpierre, M.M. Le Beau, R. Espinosa III, N.Y. Ip, L. Belluscio, and S.M. de la Monte Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations Genomics 10 1991 558 568
16. A.E. Edling, T. Nanavati, J.M. Johnson, and V.K. Tuohy Human and murine lymphocyte neurotrophin expression is confined to B cells J Neurosci Res 77 2004 709 717 (Pubitemid 39194612)
17. M. Kerschensteiner, E. Gallmeier, L. Behrens, V.V. Leal, T. Misgeld, and W.E. Klinkert Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med 189 1999 865 870 (Pubitemid 29189691)
18. O. Schulte-Herbruggen, C. Nassenstein, M. Lommatzsch, D. Quarcoo, H. Renz, and A. Braun Tumor necrosis factor-alpha and interleukin-6 regulate secretion of brain-derived neurotrophic factor in human monocytes J Neuroimmunol 160 2005 204 209 (Pubitemid 40248610)
19. W.A. Nockher, and H. Renz Neurotrophins in clinical diagnostics: pathophysiology and laboratory investigation Clin Chim Acta 352 2005 49 74 (Pubitemid 40093857)
20. U. Raap, C. Goltz, N. Deneka, M. Bruder, H. Renz, and A. Kapp Brain-derived neurotrophic factor is increased in atopic dermatitis and modulates eosinophil functions compared with that seen in nonatopic subjects J Allergy Clin Immunol 115 2005 1268 1275 (Pubitemid 40824601)
21. R.N. Pearse, S.L. Swendeman, Y. Li, D. Rafii, and B.L. Hempstead A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival Blood 105 2005 4429 4436 (Pubitemid 40720791)
22. Z.F. Yang, D.W. Ho, C.K. Lau, K.H. Tam, C.T. Lam, and R.T.P. Poon Platelet activation during tumor development, the potential role of BDNF-TrkB autocrine loop Biochem Biophys Res Commun 346 2006 981 985
23. H. Fujimura, C.A. Altar, R. Chen, T. Nakamura, T. Nakahashi, and J. Kambayashi Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation Thromb Haemost 87 2002 728 734 (Pubitemid 34302963)
24. H. Yamamoto, and M.E. Gurney Human platelets contain brain-derived neurotrophic factor J Neurosci 10 1990 3469 3478
25. M. Lommatzsch, D. Zingler, K. Schuhbaeck, K. Schloetcke, C. Zingler, and P. Schuff-Werner The impact of age, weight and gender on BDNF levels in human platelets and plasma Neurobiol Aging 26 2005 115 123 (Pubitemid 39600596)
26. T.R. Faruqi, E.J. Weiss, M.J. Shapiro, W. Huang, and S.R. Coughlin Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. Determinants of specificity and utility in assays of receptor function J Biol Chem 275 2000 19728 19734 (Pubitemid 30441571)
27. J.E. Italiano Jr., J.L. Richardson, S. Patel-Hett, E. Battinelli, A. Zaslavsky, and S. Short Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released Blood 111 2008 1227 1233 (Pubitemid 351213404)
28. K. Hara, Y. Hirowatari, M. Yoshika, Y. Komiyama, Y. Tsuka, and H. Takahashi The ratio of plasma to whole-blood serotonin may be a novel marker of atherosclerotic cardiovascular disease J Lab Clin Med 144 2004 31 37 (Pubitemid 38900806)
29. Y. Hirowatari, K. Hara, H. Kamihata, T. Iwasaka, and H. Takahashi High-performance liquid chromatographic method with column-switching and post-column reaction for determination of serotonin levels in platelet-poor plasma Clin Biochem 37 2004 191 197 (Pubitemid 38221566)
30. H. Suzuki, M.A. Packham, and R.L. Kinlough-Rathbone Effects of thrombin and the thrombin receptor activating peptide, SFLLRN, on redistribution of platelet alpha-granule contents are similar and independent of the extent of thromboxane formation Exp Mol Pathol 62 1995 63 72
31. H. Suzuki, H. Yamazaki, and K. Tanoue Immunocytochemical aspects of platelet membrane glycoproteins and adhesive proteins during activation Prog Histochem Cytochem 30 1996 1 106 (Pubitemid 3016197)
32. H. Suzuki, S. Nakamura, Y. Itoh, T. Tanaka, H. Yamazaki, and K. Tanoue Immunocytochemical evidence for the translocation of alpha-granule membrane glycoprotein IIb/IIIa (integrin alpha IIb beta 3) of human platelets to the surface membrane during the release reaction Histochemistry 97 1992 381 388
33. K.T. Tokuyasu Use of poly(vinylpyrrolidone) and poly(vinyl alcohol) for cryoultramicrotomy Histochem J 21 1989 163 171 (Pubitemid 19138135)
34. D.M. Maynard, H.F. Heijnen, W.A. Gahl, M. Gunay-Aygun, and W.A. Gahl The alpha-granule proteome: novel proteins in normal and ghost granules in gray platelet syndrome J Thromb Haemost 8 2010 1786 1796
35. D.M. Maynard, H.F. Heijnen, M.K. Horne, J.G. White, and W.A. Gahl Proteomic analysis of platelet alpha-granules using mass spectrometry J Thromb Haemost 5 2007 1945 1955 (Pubitemid 47288954)
36. M.L. Bilodeau, and H.E. Hamm Regulation of protease-activated receptor (PAR) 1 and PAR4 signaling in human platelets by compartmentalized cyclic nucleotide actions J Pharmacol Exp Ther 322 2007 778 788 (Pubitemid 47105777)
37. M. Holinstat, B. Voss, M.L. Bilodeau, J.N. McLaughlin, J. Cleator, and H.E. Hamm PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation J Biol Chem 281 2006 26665 26674 (Pubitemid 44401875)
38. F. Karege, G. Bondolfi, N. Gervasoni, M. Schwald, J.M. Aubry, and G. Bertschy Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity Biol Psychiatry 57 2005 1068 1072 (Pubitemid 40613035)
39. J.E. Italiano Jr., and E.M. Battinelli Selective sorting of alpha-granule proteins J Thromb Haemost 7 Suppl 1 2009 173 176
40. M.J. Donovan, M.I. Lin, P. Wiegn, T. Ringstedt, R. Kraemer, and R. Hahn Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization Development 127 2000 4531 4540
41. P. Kermani, D. Rafii, D.K. Jin, P. Whitlock, W. Schaffer, and A. Chiang Neurotrophins promote revascularization by local recruitment of TrkB + endothelial cells and systemic mobilization of hematopoietic progenitors J Clin Invest 115 2005 653 663 (Pubitemid 40322239)
42. H. Kim, Q. Li, B.L. Hempstead, and J.A. Madri Paracrine and autocrine functions of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in brain-derived endothelial cells J Biol Chem 279 2004 33538 33546 (Pubitemid 39063002)
43. S.R. Macfarlane, M.J. Seatter, T. Kanke, G.D. Hunter, and R. Plevin Proteinase-activated receptors Pharmacol Rev 53 2001 245 282 (Pubitemid 32476117)
44. R.J. Boado, Y. Zhang, and W.M. Pardridge Genetic engineering, expression, and activity of a fusion protein of a human neurotrophin and a molecular Trojan horse for delivery across the human blood-brain barrier Biotechnol Bioeng 97 2007 1376 1386 (Pubitemid 47204016)