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Volumn 12, Issue 8, 2013, Pages 393-398

The correlation and relationship of obesity and cancer: A possible research perspective

Author keywords

cancer; correlation; obesity; relationship

Indexed keywords

ADIPOCYTOKINE; ANDROGEN; EPIDERMAL GROWTH FACTOR; ESTROGEN; FATTY ACID SYNTHASE; GLUTAMINE; HYPOXIA INDUCIBLE FACTOR 1; INSULIN; INTERLEUKIN 6; LEPTIN; MYC PROTEIN; PROGESTERONE; PROTEIN KINASE B; PYRUVATE KINASE; SOMATOMEDIN C; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84890415697     PISSN: 16101979     EISSN: 16139089     Source Type: Journal    
DOI: 10.1007/s10330-012-1076-8     Document Type: Article
Times cited : (4)

References (50)
  • 1
    • 77950020302 scopus 로고    scopus 로고
    • World Health Organisation
    • World Health Organisation. Fact Sheet No. 311. Obesity and Overweight. 2012. WHO Media centre.
    • (2012) Fact Sheet No. 311
  • 2
    • 84890403591 scopus 로고    scopus 로고
    • World Health Organization
    • World Health Organization. Global prevalence of obesity. 2012. Available at: https://apps.who.int/infobase/Comparisons.aspx.
    • (2012) Global Prevalence of Obesity
  • 3
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U S adults
    • 12711737 10.1056/NEJMoa021423
    • Calle EE, Rodriguez C, Walker-Thurmond K, et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. New Eng J Med, 2003, 348: 1625-1638.
    • (2003) New Eng J Med , vol.348 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3
  • 4
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
    • 15286738 10.1038/nrc1408 1:CAS:528:DC%2BD2cXmtVOhsLk%3D
    • Calle EC, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nature Reviews. Cancer, 2004, 4: 579-591.
    • (2004) Nature Reviews. Cancer , vol.4 , pp. 579-591
    • Calle, E.C.1    Kaaks, R.2
  • 6
    • 34247869042 scopus 로고    scopus 로고
    • The role of obe-sity and related metabolic disturbances in cancers of the colon, prostate, and pancreas
    • 17498513 10.1053/j.gastro.2007.03.050 1:CAS:528:DC%2BD2sXmsVyns7Y%3D
    • Giovannucci E, Michaud D. The role of obe-sity and related metabolic disturbances in cancers of the colon, prostate, and pancreas. Gastroenterology, 2007, 132: 2208-2225.
    • (2007) Gastroenterology , vol.132 , pp. 2208-2225
    • Giovannucci, E.1    Michaud, D.2
  • 7
    • 0038279359 scopus 로고    scopus 로고
    • Decreased mortality associated with the use of metformin compared with sulfonylurea monotherapy in type 2 diabetes
    • 12453968 10.2337/diacare.25.12.2244 1:CAS:528:DC%2BD38Xps1Kks7s%3D
    • Johnson JA, Majumdar SR, Simpson SH, et al. Decreased mortality associated with the use of metformin compared with sulfonylurea monotherapy in type 2 diabetes. Diabetes Care, 2002, 25: 2244-2248.
    • (2002) Diabetes Care , vol.25 , pp. 2244-2248
    • Johnson, J.A.1    Majumdar, S.R.2    Simpson, S.H.3
  • 8
    • 33845485257 scopus 로고    scopus 로고
    • Epidemiology and pathogenesis of esophageal cancer
    • 17185192 10.1016/j.semradonc.2006.09.003
    • Holmes RS, Vaughan TL. Epidemiology and pathogenesis of esophageal cancer. Semin Radiat Oncol, 2007, 17: 2-9.
    • (2007) Semin Radiat Oncol , vol.17 , pp. 2-9
    • Holmes, R.S.1    Vaughan, T.L.2
  • 9
    • 34047250459 scopus 로고    scopus 로고
    • Obesity, diet and risk of non-Hodgkin lymphoma
    • 10.1158/1055-9965.EPI-06-1081 1:CAS:528:DC%2BD2sXjt1SrtrY%3D
    • Skibola CF. Obesity, diet and risk of non-Hodgkin lymphoma. Cancer Epidemiol, Biomarkers & Prev, 2007, 16: 392-395.
    • (2007) Cancer Epidemiol, Biomarkers & Prev , vol.16 , pp. 392-395
    • Skibola, C.F.1
  • 10
    • 0035313592 scopus 로고    scopus 로고
    • High-grade prostate cancer is associated with low serum testosterone levels
    • 11304729 10.1002/pros.1046 1:CAS:528:DC%2BD3MXjtVCju74%3D
    • Schatzl G, Madersbacher S, Thurridl T. High-grade prostate cancer is associated with low serum testosterone levels. Prostate, 2001, 47: 52-58.
    • (2001) Prostate , vol.47 , pp. 52-58
    • Schatzl, G.1    Madersbacher, S.2    Thurridl, T.3
  • 11
    • 33748755434 scopus 로고    scopus 로고
    • Obesity as a risk factor for development and poor prognosis of breast cancer
    • 10.1111/j.1471-0528.2006.01021.x 1:STN:280:DC%2BD28rkslOiug%3D%3D
    • Carmichael AR. Obesity as a risk factor for development and poor prognosis of breast cancer. Bri J Obst Gyn, 2006, 113: 1160-1166.
    • (2006) Bri J Obst Gyn , vol.113 , pp. 1160-1166
    • Carmichael, A.R.1
  • 12
    • 25444485782 scopus 로고    scopus 로고
    • The impact of obesity on the incidence and treatment of gyneco-logic cancers: A review
    • 10.1097/01.ogx.0000180866.62409.01
    • Modesitt SC, Nagell JR, Jr. The impact of obesity on the incidence and treatment of gyneco-logic cancers: a review. Obst & Gyn Surv, 2005, 60: 683-692.
    • (2005) Obst & Gyn Surv , vol.60 , pp. 683-692
    • Modesitt, S.C.1    Nagell, Jr.J.R.2
  • 13
    • 33947537241 scopus 로고    scopus 로고
    • Mechanisms of disease: Adipokines and breast cancer - Endocrine and paracrine mechanisms that connect adiposity and breast cancer
    • 17377617 10.1038/ncpendmet0456
    • Schäffler A, Schölmerich J, Buechler C. Mechanisms of disease: adipokines and breast cancer - endocrine and paracrine mechanisms that connect adiposity and breast cancer. Nat Clin Pract Endocrinol Metab, 2007, 3: 345-354.
    • (2007) Nat Clin Pract Endocrinol Metab , vol.3 , pp. 345-354
    • Schäffler, A.1    Schölmerich, J.2    Buechler, C.3
  • 14
    • 0036907571 scopus 로고    scopus 로고
    • Obesity, endogenous hormones, and endometrial cancer risk: A synthetic review
    • 1:CAS:528:DC%2BD3sXmsF2msQ%3D%3D
    • Kaaks R, Lukanova A, Kurzer MS. Obesity, endogenous hormones, and endometrial cancer risk: a synthetic review. Cancer Epidemiol, Biomarkers & Prev, 2002, 11: 1531-1543.
    • (2002) Cancer Epidemiol, Biomarkers & Prev , vol.11 , pp. 1531-1543
    • Kaaks, R.1    Lukanova, A.2    Kurzer, M.S.3
  • 15
    • 38949108241 scopus 로고    scopus 로고
    • Body-mass index and incidence of cancer: A systematic review and meta-analysis of prospective observational studies
    • 18280327 10.1016/S0140-6736(08)60269-X
    • Renehan AG, Tyson M, Egger M. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet, 2008, 371: 569-578.
    • (2008) Lancet , vol.371 , pp. 569-578
    • Renehan, A.G.1    Tyson, M.2    Egger, M.3
  • 16
    • 75949102926 scopus 로고    scopus 로고
    • Biological mechanisms linking obesity and cancer risk: New perspectives
    • 19824817 10.1146/annurev.med.080708.082713 1:CAS:528:DC%2BC3cXisFylsb0%3D
    • Roberts DL, Dive C, Renehan AG. 2010. Biological mechanisms linking obesity and cancer risk: new perspectives. Annu Rev Med, 2010, 61: 301-316.
    • (2010) Annu Rev Med , vol.61 , pp. 301-316
    • Roberts, D.L.1    Dive, C.2    Renehan, A.G.3
  • 17
    • 0028113617 scopus 로고
    • Epidemiology of colorectal cancer revisited: Are serum triglycerides and/or plasma glucose associated with risk?
    • 7881343 1:STN:280:DyaK2M7oslSktA%3D%3D
    • McKeown-Eyssen G. Epidemiology of colorectal cancer revisited: are serum triglycerides and/or plasma glucose associated with risk? Cancer Epidemiol Biomarkers Prev, 1994, 3: 687-695.
    • (1994) Cancer Epidemiol Biomarkers Prev , vol.3 , pp. 687-695
    • McKeown-Eyssen, G.1
  • 18
    • 0028987002 scopus 로고
    • Insulin and colon cancer
    • 7749056 10.1007/BF00052777 1:STN:280:DyaK2M3msl2kuw%3D%3D
    • Giovannucci E. Insulin and colon cancer. Cancer Causes Control, 1995, 6: 164-179.
    • (1995) Cancer Causes Control , vol.6 , pp. 164-179
    • Giovannucci, E.1
  • 19
    • 0038398622 scopus 로고    scopus 로고
    • The insulin-like growth factor system and cancer
    • 12767520 10.1016/S0304-3835(03)00159-9 1:CAS:528:DC%2BD3sXktFWmsrk%3D
    • LeRoith D, Roberts CT Jr. The insulin-like growth factor system and cancer. Cancer Lett, 2003, 195: 127-137.
    • (2003) Cancer Lett , vol.195 , pp. 127-137
    • Leroith, D.1    Roberts, Jr.C.T.2
  • 20
    • 0035843148 scopus 로고    scopus 로고
    • Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation
    • 11313952 10.1038/sj.onc.1204064 1:CAS:528:DC%2BD3MXhtFCjsrk%3D
    • Desbois-Mouthon C, Cadoret A. Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation. Oncogene, 2001, 20: 252-259.
    • (2001) Oncogene , vol.20 , pp. 252-259
    • Desbois-Mouthon, C.1    Cadoret, A.2
  • 21
    • 34249935055 scopus 로고    scopus 로고
    • Endocrinology of adipose tissue - An update
    • 17533572 10.1055/s-2007-976539 1:CAS:528:DC%2BD2sXntlKltL4%3D
    • Fischer-Posovszky P, Wabitsch M, Hochberg Z. Endocrinology of adipose tissue - an update. Horm Metab Res, 2007, 39: 314-321.
    • (2007) Horm Metab Res , vol.39 , pp. 314-321
    • Fischer-Posovszky, P.1    Wabitsch, M.2    Hochberg, Z.3
  • 22
    • 34547741589 scopus 로고    scopus 로고
    • Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression
    • 17639037 10.1677/ERC-06-0068 1:CAS:528:DC%2BD2sXhtV2lsr%2FE
    • Vona-Davis L, Rose DP. Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression. Endocr Relat Cancer, 2007, 14: 189-206.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 189-206
    • Vona-Davis, L.1    Rose, D.P.2
  • 23
    • 0345060444 scopus 로고    scopus 로고
    • Association of serum adiponectin levels with breast cancer risk
    • 14654554 1:CAS:528:DC%2BD3sXpsVeju74%3D
    • Miyoshi Y, Funahashi T, Kihara S. Association of serum adiponectin levels with breast cancer risk. Clin Cancer Res, 2003, 9: 5699-5704.
    • (2003) Clin Cancer Res , vol.9 , pp. 5699-5704
    • Miyoshi, Y.1    Funahashi, T.2    Kihara, S.3
  • 24
    • 20444468895 scopus 로고    scopus 로고
    • Prostate cancer and adiponectin
    • 15922427 10.1016/j.urology.2004.12.053
    • Goktas S, Yilmaz MI, Caglar K. Prostate cancer and adiponectin. Urology, 2005, 65: 1168-1172.
    • (2005) Urology , vol.65 , pp. 1168-1172
    • Goktas, S.1    Yilmaz, M.I.2    Caglar, K.3
  • 26
    • 25844457693 scopus 로고    scopus 로고
    • Obesity
    • 16198769 10.1016/S0140-6736(05)67483-1
    • Haslam DW, James WP. Obesity. Lancet, 2005, 366: 1197-1209.
    • (2005) Lancet , vol.366 , pp. 1197-1209
    • Haslam, D.W.1    James, W.P.2
  • 27
    • 44849116310 scopus 로고    scopus 로고
    • The perfect storm: Obesity, adipocyte dysfunction, and metabolic consequences
    • 18436717 10.1373/clinchem.2007.100156
    • De Ferranti S, Mozaffarian D. The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences. Clin Chem, 2008, 54: 945-955.
    • (2008) Clin Chem , vol.54 , pp. 945-955
    • De Ferranti, S.1    Mozaffarian, D.2
  • 28
    • 34748912615 scopus 로고    scopus 로고
    • Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
    • 17882277 10.1038/nrc2222 1:CAS:528:DC%2BD2sXhtVOnsr3P
    • Menendez JA, Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer, 2007, 7: 763-777.
    • (2007) Nat Rev Cancer , vol.7 , pp. 763-777
    • Menendez, J.A.1    Lupu, R.2
  • 29
    • 33745728461 scopus 로고    scopus 로고
    • Fatty acid synthase and cancer: New application of an old pathway
    • 16778164 10.1158/0008-5472.CAN-05-4673 1:CAS:528:DC%2BD28XlvVSltbs%3D
    • Kuhajda FK. Fatty acid synthase and cancer: new application of an old pathway. Cancer Res, 2006, 66: 5977-5980.
    • (2006) Cancer Res , vol.66 , pp. 5977-5980
    • Kuhajda, F.K.1
  • 30
    • 0034650757 scopus 로고    scopus 로고
    • Malonyl coenzyme A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts
    • 10667561 1:CAS:528:DC%2BD3cXhtVaiu7k%3D
    • Pizer ES, Thupari J, Han WF. Malonyl coenzyme A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. Cancer Res, 2000, 60: 213-218.
    • (2000) Cancer Res , vol.60 , pp. 213-218
    • Pizer, E.S.1    Thupari, J.2    Han, W.F.3
  • 31
    • 0242694902 scopus 로고    scopus 로고
    • Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells
    • 14612531 1:CAS:528:DC%2BD3sXovVGlt7Y%3D
    • Zhou W, Simpson PJ, McFadden JM. Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells. Cancer Res, 2003, 63: 7330-7337.
    • (2003) Cancer Res , vol.63 , pp. 7330-7337
    • Zhou, W.1    Simpson, P.J.2    McFadden, J.M.3
  • 32
    • 3242685815 scopus 로고    scopus 로고
    • Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells
    • 15235125 10.1073/pnas.0403390101 1:CAS:528:DC%2BD2cXmtFWmt74%3D
    • Menendez JA, Vellon L, Mehmi I. Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells. Proc Natl Acad Sci, 2004, 101: 10715-10720.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 10715-10720
    • Menendez, J.A.1    Vellon, L.2    Mehmi, I.3
  • 33
    • 19944374798 scopus 로고    scopus 로고
    • Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells
    • 15806173 10.1038/sj.onc.1208463 1:CAS:528:DC%2BD2MXktlWisbw%3D
    • Wang HQ, Altomare DA, Skele KL. Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells. Oncogene, 2005, 24: 3574-3582.
    • (2005) Oncogene , vol.24 , pp. 3574-3582
    • Wang, H.Q.1    Altomare, D.A.2    Skele, K.L.3
  • 34
    • 0036385719 scopus 로고    scopus 로고
    • Activation of fatty acid synthesis during neoplastic transformation: Role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
    • 12213216 10.1006/excr.2002.5600 1:CAS:528:DC%2BD38XmsV2ktrY%3D
    • Yang YA, Han WF, Morin PJ. Activation of fatty acid synthesis during neoplastic transformation: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Exp Cell Res, 2002, 279: 80-90.
    • (2002) Exp Cell Res , vol.279 , pp. 80-90
    • Yang, Y.A.1    Han, W.F.2    Morin, P.J.3
  • 35
    • 84863964058 scopus 로고    scopus 로고
    • Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma
    • 10.1073/pnas.1205995109
    • Aadra PB, Sarah RJ, Alex J. Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma. Proc Natl Acad Sci, 2012, 109: 11818-11823.
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 11818-11823
    • Aadra, P.B.1    Sarah, R.J.2    Alex, J.3
  • 36
    • 19944374798 scopus 로고    scopus 로고
    • Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells
    • 15806173 10.1038/sj.onc.1208463 1:CAS:528:DC%2BD2MXktlWisbw%3D
    • Wang HQ, Altomare DA, Skele KL. Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells. Oncogene, 2005, 24: 3574-3582.
    • (2005) Oncogene , vol.24 , pp. 3574-3582
    • Wang, H.Q.1    Altomare, D.A.2    Skele, K.L.3
  • 37
    • 2542561169 scopus 로고    scopus 로고
    • Akt stimulates aerobic glycolysis in cancer cells
    • 15172999 10.1158/0008-5472.CAN-03-2904 1:CAS:528:DC%2BD2cXksVKnsrs%3D
    • Elstrom RL, Bauer DE, Buzzai M. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res, 2004, 64: 3892-3899.
    • (2004) Cancer Res , vol.64 , pp. 3892-3899
    • Elstrom, R.L.1    Bauer, D.E.2    Buzzai, M.3
  • 38
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • 13298683 10.1126/science.123.3191.309 1:STN:280:DyaG28%2FltV2ktQ%3D%3D
    • Warburg O. On the origin of cancer cells. Science, 1956, 123: 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 39
    • 23044500915 scopus 로고    scopus 로고
    • Pyruvatekinase type M2 and its role in tumor growth and spreading
    • 15908230 10.1016/j.semcancer.2005.04.009 1:CAS:528:DC%2BD2MXmvVKntbw%3D
    • Mazurek S, Boschek CB, Hugo F, et al. Pyruvatekinase type M2 and its role in tumor growth and spreading. Semin Cancer Biol, 2005, 15: 300-308.
    • (2005) Semin Cancer Biol , vol.15 , pp. 300-308
    • Mazurek, S.1    Boschek, C.B.2    Hugo, F.3
  • 40
    • 37449034854 scopus 로고    scopus 로고
    • Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
    • 18032601 10.1073/pnas.0709747104 1:CAS:528:DC%2BD1cXisVOjtQ%3D%3D
    • DeBerardinis RJ, Mancuso A, Daikhin E, et al. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci U S A, 2007, 104: 19345-19350.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19345-19350
    • Deberardinis, R.J.1    Mancuso, A.2    Daikhin, E.3
  • 41
    • 0018386209 scopus 로고
    • Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells
    • 429309 1:CAS:528:DyaE1MXktVehtLY%3D
    • Reitzer LJ, Wice BM, Kennell D. Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells. J Biol Chem, 1979, 254: 2669-2676.
    • (1979) J Biol Chem , vol.254 , pp. 2669-2676
    • Reitzer, L.J.1    Wice, B.M.2    Kennell, D.3
  • 42
    • 0033620972 scopus 로고    scopus 로고
    • Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing
    • 11015561
    • Elgadi KM, Meguid RA, Qian M, et al. Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing. Physiol Genomics, 1999, 1: 51-62.
    • (1999) Physiol Genomics , vol.1 , pp. 51-62
    • Elgadi, K.M.1    Meguid, R.A.2    Qian, M.3
  • 43
    • 0026009359 scopus 로고
    • Inhibition and stimulation of c-myc gene transcription by insulin in rat hepatoma cells. Insulin alters the intragenic pausing of c-myc transcription
    • 1917937 1:CAS:528:DyaK3MXlt1Ortrw%3D
    • Messina JL. Inhibition and stimulation of c-myc gene transcription by insulin in rat hepatoma cells. Insulin alters the intragenic pausing of c-myc transcription. J Biol Chem, 1991, 266: 17995-8001.
    • (1991) J Biol Chem , vol.266 , pp. 17995-18001
    • Messina, J.L.1
  • 44
    • 33745886839 scopus 로고    scopus 로고
    • Leptin-induced growth of human ZR-75-1 breast cancer cells is associated with up-regulation of cyclin D1 and c-Myc and down-regulation of tumor suppressor p53 and p21WAF1/CIP1
    • 16752079 10.1007/s10549-005-9139-y 1:CAS:528:DC%2BD28XmvVarsrg%3D
    • Chen C, Chang YC, Liu CL, et al. Leptin-induced growth of human ZR-75-1 breast cancer cells is associated with up-regulation of cyclin D1 and c-Myc and down-regulation of tumor suppressor p53 and p21WAF1/CIP1. Breast Cancer Res Treat, 2006, 98: 121-132.
    • (2006) Breast Cancer Res Treat , vol.98 , pp. 121-132
    • Chen, C.1    Chang, Y.C.2    Liu, C.L.3
  • 45
    • 75149150660 scopus 로고    scopus 로고
    • HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
    • 20010808 10.1038/nature08697 1:CAS:528:DC%2BD1MXhsFGjsLfO
    • David CJ, Chen M, Assanah M, et al. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature, 2010, 463: 364-368.
    • (2010) Nature , vol.463 , pp. 364-368
    • David, C.J.1    Chen, M.2    Assanah, M.3
  • 46
    • 79960006190 scopus 로고    scopus 로고
    • 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression
    • 21723511 10.1016/j.cmet.2011.04.012 1:CAS:528:DC%2BC3MXosFeitLk%3D
    • Hu S, Balakrishnan A, Bok RA, et al. 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression. Cell Metab, 2011, 14: 131-142.
    • (2011) Cell Metab , vol.14 , pp. 131-142
    • Hu, S.1    Balakrishnan, A.2    Bok, R.A.3
  • 47
    • 64749116346 scopus 로고    scopus 로고
    • C-Myc suppression of miR-23 enhances mitochondrial glutaminase and glutamine metabolism
    • 19219026 10.1038/nature07823 1:CAS:528:DC%2BD1MXhvFKjtrY%3D
    • Gao P, Tchernyshyov I, Chang TC, et al. c-Myc suppression of miR-23 enhances mitochondrial glutaminase and glutamine metabolism. Nature, 2009, 458: 762-765.
    • (2009) Nature , vol.458 , pp. 762-765
    • Gao, P.1    Tchernyshyov, I.2    Chang, T.C.3
  • 48
    • 43749083041 scopus 로고    scopus 로고
    • Brick by brick: Metabolism and tumor cell growth
    • 18387799 10.1016/j.gde.2008.02.003 1:CAS:528:DC%2BD1cXmsVartbg%3D
    • Deberardinis RJ, Sayed N, Ditsworth D, et al. Brick by brick: metabolism and tumor cell growth. Curr Opin Genet Dev, 2008, 18: 54-61.
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 54-61
    • Deberardinis, R.J.1    Sayed, N.2    Ditsworth, D.3
  • 49
    • 84859215796 scopus 로고    scopus 로고
    • Systemic elevation of PTEN induces a tumor-suppressive metabolic state
    • 10.1016/j.cell.2012.02.030
    • Cao IG, Song MS, Hobbs RM, et al. Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Cell, 2012, 149: 49-62.
    • (2012) Cell , vol.149 , pp. 49-62
    • Cao, I.G.1    Song, M.S.2    Hobbs, R.M.3
  • 50
    • 33846002728 scopus 로고    scopus 로고
    • A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
    • 17222789 10.1016/j.ccr.2006.10.020 1:CAS:528:DC%2BD2sXhtFClsLg%3D
    • Bonnet S, Archer SL, Allalunis-Turner J, et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell, 2007, 11: 37-51.
    • (2007) Cancer Cell , vol.11 , pp. 37-51
    • Bonnet, S.1    Archer, S.L.2    Allalunis-Turner, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.