-
1
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
PID: 15164071, COI: 1:CAS:528:DC%2BD2cXkt1Onsb0%3D
-
Egger G, Liang G, Aparicio A, Jones PA (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429:457–463
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
2
-
-
39649122136
-
Cancer epigenetics: modifications, screening, and therapy
-
PID: 17937590, COI: 1:CAS:528:DC%2BD1cXis12nurw%3D
-
Gal-Yam EN, Saito Y, Egger G, Jones PA (2008) Cancer epigenetics: modifications, screening, and therapy. Annu Rev Med 59:267–280
-
(2008)
Annu Rev Med
, vol.59
, pp. 267-280
-
-
Gal-Yam, E.N.1
Saito, Y.2
Egger, G.3
Jones, P.A.4
-
3
-
-
0031860739
-
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
-
PID: 9662389, COI: 1:CAS:528:DyaK1cXls1Sns7w%3D
-
Okano M, Xie S, Li E (1998) Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat Genet 19:219–220
-
(1998)
Nat Genet
, vol.19
, pp. 219-220
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
4
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
PID: 12702868, COI: 1:CAS:528:DC%2BD3sXktlektb8%3D
-
Eden A, Gaudet F, Waghmare A, Jaenisch R (2003) Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300:455
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
5
-
-
2442454683
-
Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome
-
PID: 15123803, COI: 1:CAS:528:DC%2BD2cXksFaksLk%3D
-
Liang G, Lin JC, Wei V et al (2004) Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome. Proc Natl Acad Sci U S A 101:7357–7362
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7357-7362
-
-
Liang, G.1
Lin, J.C.2
Wei, V.3
-
6
-
-
33847076849
-
Chromatin modifications and their function
-
PID: 17320507, COI: 1:CAS:528:DC%2BD2sXis12ju7Y%3D
-
Kouzarides T (2007) Chromatin modifications and their function. Cell 128:693–705
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
7
-
-
0035839136
-
Translating the histone code
-
PID: 11498575, COI: 1:CAS:528:DC%2BD3MXmtVWltro%3D
-
Jenuwein T, Allis CD (2001) Translating the histone code. Science 293:1074–1080
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
8
-
-
44349131472
-
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
-
PID: 18488029, COI: 1:CAS:528:DC%2BD1cXmsVejtro%3D
-
Kondo Y, Shen L, Cheng AS et al (2008) Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet 40:741–750
-
(2008)
Nat Genet
, vol.40
, pp. 741-750
-
-
Kondo, Y.1
Shen, L.2
Cheng, A.S.3
-
9
-
-
33750370444
-
MicroRNA signatures in human cancers
-
PID: 17060945, COI: 1:CAS:528:DC%2BD28XhtFWhs7fM
-
Calin GA, Croce CM (2006) MicroRNA signatures in human cancers. Nat Rev Cancer 6:857–866
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
10
-
-
58849131081
-
The role of microRNAs in gastrointestinal cancers
-
PID: 19148788, COI: 1:CAS:528:DC%2BD1MXosVGqtw%3D%3D
-
Saito Y, Suzuki H, Hibi T (2009) The role of microRNAs in gastrointestinal cancers. J Gastroenterol 44(Suppl 19):18–22
-
(2009)
J Gastroenterol
, vol.44
, pp. 18-22
-
-
Saito, Y.1
Suzuki, H.2
Hibi, T.3
-
11
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
PID: 15211354, COI: 1:CAS:528:DC%2BD2cXltVSmsbw%3D
-
He L, Hannon GJ (2004) MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5:522–531
-
(2004)
Nat Rev Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
12
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
PID: 16766263, COI: 1:CAS:528:DC%2BD28Xmt1eksLY%3D
-
Saito Y, Liang G, Egger G et al (2006) Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9:435–443
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
-
13
-
-
68149126345
-
Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells
-
PID: 19503096, COI: 1:CAS:528:DC%2BD1MXntVWisL8%3D
-
Saito Y, Suzuki H, Tsugawa H et al (2009) Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells. Oncogene 28:2738–2744
-
(2009)
Oncogene
, vol.28
, pp. 2738-2744
-
-
Saito, Y.1
Suzuki, H.2
Tsugawa, H.3
-
14
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
-
PID: 17308079, COI: 1:CAS:528:DC%2BD2sXhvVWrurk%3D
-
Lujambio A, Ropero S, Ballestar E et al (2007) Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res 67:1424–1429
-
(2007)
Cancer Res
, vol.67
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
-
15
-
-
33847748913
-
The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function
-
PID: 17308078, COI: 1:CAS:528:DC%2BD2sXhvVWruro%3D
-
Brueckner B, Stresemann C, Kuner R et al (2007) The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function. Cancer Res 67:1419–1423
-
(2007)
Cancer Res
, vol.67
, pp. 1419-1423
-
-
Brueckner, B.1
Stresemann, C.2
Kuner, R.3
-
16
-
-
51649083501
-
A microRNA DNA methylation signature for human cancer metastasis
-
PID: 18768788, COI: 1:CAS:528:DC%2BD1cXhtFeqs7bF
-
Lujambio A, Calin GA, Villanueva A et al (2008) A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci U S A 105:13556–13561
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13556-13561
-
-
Lujambio, A.1
Calin, G.A.2
Villanueva, A.3
-
17
-
-
38049044753
-
Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer
-
PID: 17948228, COI: 1:CAS:528:DC%2BD1cXhtlynu7g%3D
-
Lehmann U, Hasemeier B, Christgen M et al (2008) Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer. J Pathol 214:17–24
-
(2008)
J Pathol
, vol.214
, pp. 17-24
-
-
Lehmann, U.1
Hasemeier, B.2
Christgen, M.3
-
18
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
PID: 17554337, COI: 1:CAS:528:DC%2BD2sXmvFKmu7c%3D
-
He L, He X, Lim LP et al (2007) A microRNA component of the p53 tumour suppressor network. Nature 447:1130–1134
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
-
19
-
-
34848868157
-
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
-
PID: 17875987, COI: 1:CAS:528:DC%2BD2sXhtFWqu7vL
-
Tazawa H, Tsuchiya N, Izumiya M, Nakagama H (2007) Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci U S A 104:15472–15477
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15472-15477
-
-
Tazawa, H.1
Tsuchiya, N.2
Izumiya, M.3
Nakagama, H.4
-
20
-
-
49749126791
-
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
-
PID: 18719384, COI: 1:CAS:528:DC%2BD1cXht1elsbnO
-
Lodygin D, Tarasov V, Epanchintsev A et al (2008) Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle 7:2591–2600
-
(2008)
Cell Cycle
, vol.7
, pp. 2591-2600
-
-
Lodygin, D.1
Tarasov, V.2
Epanchintsev, A.3
-
21
-
-
49249121155
-
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
-
PID: 18519671, COI: 1:CAS:528:DC%2BD1cXmsFKmtLo%3D
-
Toyota M, Suzuki H, Sasaki Y et al (2008) Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res 68:4123–4132
-
(2008)
Cancer Res
, vol.68
, pp. 4123-4132
-
-
Toyota, M.1
Suzuki, H.2
Sasaki, Y.3
-
22
-
-
48549091046
-
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis
-
PID: 18593903, COI: 1:CAS:528:DC%2BD1cXnvFOqtLg%3D
-
Datta J, Kutay H, Nasser MW et al (2008) Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res 68:5049–5058
-
(2008)
Cancer Res
, vol.68
, pp. 5049-5058
-
-
Datta, J.1
Kutay, H.2
Nasser, M.W.3
-
23
-
-
6344281172
-
Identification of mammalian microRNA host genes and transcription units
-
PID: 15364901, COI: 1:CAS:528:DC%2BD2cXotl2hu7w%3D
-
Rodriguez A, Griffiths-Jones S, Ashurst JL, Bradley A (2004) Identification of mammalian microRNA host genes and transcription units. Genome Res 14:1902–1910
-
(2004)
Genome Res
, vol.14
, pp. 1902-1910
-
-
Rodriguez, A.1
Griffiths-Jones, S.2
Ashurst, J.L.3
Bradley, A.4
-
24
-
-
33846945735
-
Processing of intronic microRNAs
-
PID: 17255951, COI: 1:CAS:528:DC%2BD2sXhtlOktrs%3D
-
Kim YK, Kim VN (2007) Processing of intronic microRNAs. EMBO J 26:775–783
-
(2007)
EMBO J
, vol.26
, pp. 775-783
-
-
Kim, Y.K.1
Kim, V.N.2
-
25
-
-
58549108465
-
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells
-
PID: 19116145, COI: 1:CAS:528:DC%2BD1MXhtFemt7w%3D
-
Saito Y, Friedman JM, Chihara Y, Egger G, Chuang JC, Liang G (2009) Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells. Biochem Biophys Res Commun 379:726–731
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 726-731
-
-
Saito, Y.1
Friedman, J.M.2
Chihara, Y.3
Egger, G.4
Chuang, J.C.5
Liang, G.6
-
26
-
-
44449125989
-
Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer
-
PID: 18264139, COI: 1:CAS:528:DC%2BD1cXntlCqurc%3D
-
Grady WM, Parkin RK, Mitchell PS et al (2008) Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer. Oncogene 27:3880–3888
-
(2008)
Oncogene
, vol.27
, pp. 3880-3888
-
-
Grady, W.M.1
Parkin, R.K.2
Mitchell, P.S.3
-
27
-
-
77954234485
-
Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1
-
PID: 20578129, COI: 1:CAS:528:DC%2BC3cXpsFSht78%3D
-
Huang J, Wang Y, Guo Y, Sun S (2010) Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1. Hepatology 52:60–70
-
(2010)
Hepatology
, vol.52
, pp. 60-70
-
-
Huang, J.1
Wang, Y.2
Guo, Y.3
Sun, S.4
-
28
-
-
80054047147
-
miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer
-
PID: 21868754, COI: 1:CAS:528:DC%2BC3MXhtlSltLnK
-
Tsuruta T, Kozaki K, Uesugi A et al (2011) miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer. Cancer Res 71:6450–6462
-
(2011)
Cancer Res
, vol.71
, pp. 6450-6462
-
-
Tsuruta, T.1
Kozaki, K.2
Uesugi, A.3
-
29
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
PID: 17890317, COI: 1:CAS:528:DC%2BD2sXhtFGns7zL
-
Fabbri M, Garzon R, Cimmino A et al (2007) MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci U S A 104:15805–15810
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
-
30
-
-
84884532954
-
Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer
-
Kim W, Bird GH, Neff T, et al. (2013) Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer. Nat Chem Biol 9:643–650
-
(2013)
Nat Chem Biol
, vol.9
, pp. 643-650
-
-
Kim, W.1
Bird, G.H.2
Neff, T.3
-
31
-
-
65549083102
-
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2
-
PID: 19258506, COI: 1:CAS:528:DC%2BD1MXjtF2jsr4%3D
-
Friedman JM, Liang G, Liu CC et al (2009) The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Res 69:2623–2629
-
(2009)
Cancer Res
, vol.69
, pp. 2623-2629
-
-
Friedman, J.M.1
Liang, G.2
Liu, C.C.3
-
32
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
PID: 19008416, COI: 1:CAS:528:DC%2BD1cXhsVOgtbvO
-
Varambally S, Cao Q, Mani RS et al (2008) Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 322:1695–1699
-
(2008)
Science
, vol.322
, pp. 1695-1699
-
-
Varambally, S.1
Cao, Q.2
Mani, R.S.3
-
33
-
-
80051590718
-
Coordinated regulation of polycomb group complexes through microRNAs in cancer
-
PID: 21840484, COI: 1:CAS:528:DC%2BC3MXhtVWrt7nE
-
Cao Q, Mani RS, Ateeq B et al (2011) Coordinated regulation of polycomb group complexes through microRNAs in cancer. Cancer Cell 20:187–199
-
(2011)
Cancer Cell
, vol.20
, pp. 187-199
-
-
Cao, Q.1
Mani, R.S.2
Ateeq, B.3
-
34
-
-
77954087192
-
Epigenetics lessons from twins: prospects for autoimmune disease
-
PID: 19653134, COI: 1:CAS:528:DC%2BC3cXnvVeku7Y%3D
-
Ballestar E (2010) Epigenetics lessons from twins: prospects for autoimmune disease. Clin Rev Allergy Immunol 39:30–41
-
(2010)
Clin Rev Allergy Immunol
, vol.39
, pp. 30-41
-
-
Ballestar, E.1
-
35
-
-
0034541591
-
Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression
-
PID: 11145021, COI: 1:CAS:528:DC%2BD3MXhtlOlsA%3D%3D
-
Neidhart M, Rethage J, Kuchen S et al (2000) Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression. Arthritis Rheum 43:2634–2647
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2634-2647
-
-
Neidhart, M.1
Rethage, J.2
Kuchen, S.3
-
36
-
-
73249146755
-
DNA hypomethylation in rheumatoid arthritis synovial fibroblasts
-
PID: 19950268, COI: 1:CAS:528:DC%2BC3cXhtFKhtb7K
-
Karouzakis E, Gay RE, Michel BA, Gay S, Neidhart M (2009) DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 60:3613–3622
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3613-3622
-
-
Karouzakis, E.1
Gay, R.E.2
Michel, B.A.3
Gay, S.4
Neidhart, M.5
-
37
-
-
49449106856
-
Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis
-
PID: 18759290
-
Nile CJ, Read RC, Akil M, Duff GW, Wilson AG (2008) Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum 58:2686–2693
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2686-2693
-
-
Nile, C.J.1
Read, R.C.2
Akil, M.3
Duff, G.W.4
Wilson, A.G.5
-
38
-
-
33744936286
-
The epigenetic face of systemic lupus erythematosus
-
PID: 16751355, COI: 1:CAS:528:DC%2BD28Xlt1CltLs%3D
-
Ballestar E, Esteller M, Richardson BC (2006) The epigenetic face of systemic lupus erythematosus. J Immunol 176:7143–7147
-
(2006)
J Immunol
, vol.176
, pp. 7143-7147
-
-
Ballestar, E.1
Esteller, M.2
Richardson, B.C.3
-
39
-
-
0035096761
-
Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients
-
PID: 11229472, COI: 1:CAS:528:DC%2BD3MXitlCgurw%3D
-
Deng C, Kaplan MJ, Yang J et al (2001) Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. Arthritis Rheum 44:397–407
-
(2001)
Arthritis Rheum
, vol.44
, pp. 397-407
-
-
Deng, C.1
Kaplan, M.J.2
Yang, J.3
-
40
-
-
70350049103
-
Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis
-
PID: 19444718, COI: 1:CAS:528:DC%2BD1MXht1CrsbnM
-
Lei W, Luo Y, Lei W et al (2009) Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis. Scand J Rheum 38:369–374
-
(2009)
Scand J Rheum
, vol.38
, pp. 369-374
-
-
Lei, W.1
Luo, Y.2
Lei, W.3
-
41
-
-
0026741293
-
Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus
-
PID: 1376122, COI: 1:CAS:528:DyaK38Xlt12ksbg%3D
-
Richardson BC, Strahler JR, Pivirotto TS et al (1992) Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus. Arthritis Rheum 35:647–662
-
(1992)
Arthritis Rheum
, vol.35
, pp. 647-662
-
-
Richardson, B.C.1
Strahler, J.R.2
Pivirotto, T.S.3
-
42
-
-
75649151209
-
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
-
PID: 20028698, COI: 1:CAS:528:DC%2BC3cXhs1GhtLg%3D
-
Javierre BM, Fernandez AF, Richter J et al (2010) Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res 20:170–179
-
(2010)
Genome Res
, vol.20
, pp. 170-179
-
-
Javierre, B.M.1
Fernandez, A.F.2
Richter, J.3
-
43
-
-
1542724431
-
Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells
-
PID: 15004168, COI: 1:CAS:528:DC%2BD2cXhvVKisrw%3D
-
Kaplan MJ, Lu Q, Wu A, Attwood J, Richardson B (2004) Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells. J Immunol 172:3652–3661
-
(2004)
J Immunol
, vol.172
, pp. 3652-3661
-
-
Kaplan, M.J.1
Lu, Q.2
Wu, A.3
Attwood, J.4
Richardson, B.5
-
44
-
-
0036095885
-
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus
-
PID: 12115234, COI: 1:CAS:528:DC%2BD38XksVynsrs%3D
-
Lu Q, Kaplan M, Ray D et al (2002) Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus. Arthritis Rheum 46:1282–1291
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1282-1291
-
-
Lu, Q.1
Kaplan, M.2
Ray, D.3
-
45
-
-
38449116161
-
Demethylation of CD40LG on the inactive X in T cells from women with lupus
-
PID: 17947713, COI: 1:CAS:528:DC%2BD2sXhtFyksr3E
-
Lu Q, Wu A, Tesmer L, Ray D, Yousif N, Richardson B (2007) Demethylation of CD40LG on the inactive X in T cells from women with lupus. J Immunol 179:6352–6358
-
(2007)
J Immunol
, vol.179
, pp. 6352-6358
-
-
Lu, Q.1
Wu, A.2
Tesmer, L.3
Ray, D.4
Yousif, N.5
Richardson, B.6
-
46
-
-
2642556447
-
Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors
-
PID: 15188362, COI: 1:CAS:528:DC%2BD2cXlsFaqtLc%3D
-
Oelke K, Lu Q, Richardson D et al (2004) Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors. Arthritis Rheum 50:1850–1860
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1850-1860
-
-
Oelke, K.1
Lu, Q.2
Richardson, D.3
-
47
-
-
66949176660
-
IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation
-
PID: 19380809, COI: 1:CAS:528:DC%2BD1MXkslKhsr4%3D
-
Garaud S, Le Dantec C, Jousse-Joulin S et al (2009) IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation. J Immunol 182:5623–5632
-
(2009)
J Immunol
, vol.182
, pp. 5623-5632
-
-
Garaud, S.1
Le Dantec, C.2
Jousse-Joulin, S.3
-
48
-
-
75649139134
-
Physiological and pathological roles for microRNAs in the immune system
-
PID: 20098459
-
O'Connell RM, Rao DS, Chaudhuri AA, Baltimore D (2010) Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol 10:111–122
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 111-122
-
-
O'Connell, R.M.1
Rao, D.S.2
Chaudhuri, A.A.3
Baltimore, D.4
-
49
-
-
77953624215
-
MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1
-
PID: 20483747, COI: 1:CAS:528:DC%2BC3cXmvFejsrw%3D
-
Pan W, Zhu S, Yuan M et al (2010) MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol 184:6773–6781
-
(2010)
J Immunol
, vol.184
, pp. 6773-6781
-
-
Pan, W.1
Zhu, S.2
Yuan, M.3
-
50
-
-
79955569628
-
MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1
-
PID: 21538319, COI: 1:CAS:528:DC%2BC3MXltlGht70%3D
-
Zhao S, Wang Y, Liang Y et al (2011) MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. Arthritis Rheum 63:1376–1386
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1376-1386
-
-
Zhao, S.1
Wang, Y.2
Liang, Y.3
-
51
-
-
37849031502
-
Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients
-
PID: 18042587, COI: 1:CAS:528:DC%2BD1cXhtlOqs7w%3D
-
Dai Y, Huang YS, Tang M et al (2007) Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients. Lupus 16:939–946
-
(2007)
Lupus
, vol.16
, pp. 939-946
-
-
Dai, Y.1
Huang, Y.S.2
Tang, M.3
-
52
-
-
65249138193
-
MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins
-
PID: 19333922, COI: 1:CAS:528:DC%2BD1MXltFemsr8%3D
-
Tang Y, Luo X, Cui H et al (2009) MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins. Arthritis Rheum 60:1065–1075
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1065-1075
-
-
Tang, Y.1
Luo, X.2
Cui, H.3
-
53
-
-
84857887315
-
Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance
-
PID: 22161761, COI: 1:CAS:528:DC%2BC38XnsFOltb4%3D
-
Niederer F, Trenkmann M, Ospelt C et al (2012) Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance. Arthritis Rheum 64:1771–1779
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1771-1779
-
-
Niederer, F.1
Trenkmann, M.2
Ospelt, C.3
-
54
-
-
42449156220
-
Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis
-
PID: 18383392
-
Stanczyk J, Pedrioli DM, Brentano F et al (2008) Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum 58:1001–1009
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1001-1009
-
-
Stanczyk, J.1
Pedrioli, D.M.2
Brentano, F.3
-
55
-
-
79551655444
-
Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation
-
PID: 21279994
-
Stanczyk J, Ospelt C, Karouzakis E et al (2011) Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum 63:373–381
-
(2011)
Arthritis Rheum
, vol.63
, pp. 373-381
-
-
Stanczyk, J.1
Ospelt, C.2
Karouzakis, E.3
-
56
-
-
43949136123
-
Expression of microRNA-146 in rheumatoid arthritis synovial tissue
-
PID: 18438844, COI: 1:CAS:528:DC%2BD1cXms1ehu7w%3D
-
Nakasa T, Miyaki S, Okubo A et al (2008) Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis Rheum 58:1284–1292
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1284-1292
-
-
Nakasa, T.1
Miyaki, S.2
Okubo, A.3
-
57
-
-
52249094653
-
Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients
-
Pauley KM, Satoh M, Chan AL, Bubb MR, Reeves WH, Chan EK (2008) Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther. 10(4):R101
-
(2008)
Arthritis Res Ther
, vol.10
, Issue.4
, pp. R101
-
-
Pauley, K.M.1
Satoh, M.2
Chan, A.L.3
Bubb, M.R.4
Reeves, W.H.5
Chan, E.K.6
-
58
-
-
67651113615
-
Differential micro RNA expression in PBMC from multiple sclerosis patients
-
PID: 19617918
-
Otaegui D, Baranzini SE, Armananzas R et al (2009) Differential micro RNA expression in PBMC from multiple sclerosis patients. PloS One 4:e6309
-
(2009)
PloS One
, vol.4
, pp. e6309
-
-
Otaegui, D.1
Baranzini, S.E.2
Armananzas, R.3
-
59
-
-
70449716915
-
MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis
-
PID: 19838199, COI: 1:CAS:528:DC%2BD1MXht1Ogsr3F
-
Du C, Liu C, Kang J et al (2009) MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol 10:1252–1259
-
(2009)
Nat Immunol
, vol.10
, pp. 1252-1259
-
-
Du, C.1
Liu, C.2
Kang, J.3
-
60
-
-
33847065486
-
The epigenomics of cancer
-
PID: 17320506, COI: 1:CAS:528:DC%2BD2sXis12ju7k%3D
-
Jones PA, Baylin SB (2007) The epigenomics of cancer. Cell 128:683–692
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
61
-
-
55749110754
-
Demethylating agents in myeloid malignancies
-
PID: 18841054, COI: 1:CAS:528:DC%2BD1cXht1SntLfL
-
Garcia-Manero G (2008) Demethylating agents in myeloid malignancies. Curr Opin Oncol 20:705–710
-
(2008)
Curr Opin Oncol
, vol.20
, pp. 705-710
-
-
Garcia-Manero, G.1
-
62
-
-
73949128107
-
Histone deacetylase inhibitors in cancer therapy
-
COI: 1:CAS:528:DC%2BD1MXhsFKkt7vE
-
Lane AA, Chabner BA (2009) Histone deacetylase inhibitors in cancer therapy. J Clin Oncol: Off J Am Soc Clin Oncol 27:5459–5468
-
(2009)
J Clin Oncol: Off J Am Soc Clin Oncol
, vol.27
, pp. 5459-5468
-
-
Lane, A.A.1
Chabner, B.A.2
-
63
-
-
79955552937
-
Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis
-
PID: 21538322, COI: 1:CAS:528:DC%2BC3MXltlGhtrw%3D
-
Vojinovic J, Damjanov N, D'Urzo C et al (2011) Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 63:1452–1458
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1452-1458
-
-
Vojinovic, J.1
Damjanov, N.2
D'Urzo, C.3
-
64
-
-
84884908851
-
MiR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer
-
Su SF, Chang YW, Andreu-Vieyra C, et al. (2012) 32(39):4694–701
-
Su SF, Chang YW, Andreu-Vieyra C, et al. (2012) miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer. Oncogene 32(39):4694–701
-
Oncogene
-
-
-
65
-
-
79960839564
-
Creating a flexible multiple microRNA expression vector by linking precursor microRNAs
-
PID: 21726537, COI: 1:CAS:528:DC%2BC3MXps1aku7c%3D
-
Qiu X, Friedman JM, Liang G (2011) Creating a flexible multiple microRNA expression vector by linking precursor microRNAs. Biochem Biophys Res Commun 411:276–280
-
(2011)
Biochem Biophys Res Commun
, vol.411
, pp. 276-280
-
-
Qiu, X.1
Friedman, J.M.2
Liang, G.3
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