Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1843, Issue 2, 2014, Pages 253-264

  Misheva, Mariya ^a   Kaur, Gurpreet ^b,c   Ngoei, Kevin R W ^a   Yeap, Yvonne Y ^a   Ng, Ivan H W ^a,b   Wagstaff, Kylie M ^b   Ng, Dominic C H ^a   Jans, David A ^b   Bogoyevitch, Marie A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Fluorescence recovery after photobleaching; Live imaging; Nuclear import; Sorbitol

Indexed keywords

KARYOPHERIN ALPHA; KARYOPHERIN ALPHA2; KARYOPHERIN BETA; KARYOPHERIN BETA1; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR NF E2 P45 SUBUNIT; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GLOBAL CHANGE; HUMAN; HUMAN CELL; HYPEROSMOTIC STRESS; IMAGE ANALYSIS; IN VITRO STUDY; NUCLEAR IMPORT; NUCLEAR PORE; NUCLEAR PORE COMPLEX; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS;

5-IODOACETAMIDOFLUORESCEIN; C-JUN N-TERMINAL KINASE; CLSM; CONFOCAL LASER SCANNING MICROSCOPY; CYTOPLASMIC FLUORESCENCE; ERK; EXTRACELLULAR SIGNAL-REGULATED KINASE; FC; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FN; FN/C; FRAP; GFP; GLUTATHIONE S-TRANSFERASE; GREEN FLUORESCENT PROTEIN; GST; HTC CELLS; IAF; IMP; IMPORTIN; JNK; LIVE-IMAGING; MAPK; MAPK KINASE; MEFS; MITOGEN-ACTIVATED PROTEIN KINASE; MKK; MURINE EMBRYONIC FIBROBLASTS; NLS; NTS; NUCLEAR FACTOR ERYTHROID 2 (NF-E2); NUCLEAR FLUORESCENCE; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SEQUENCE; NUCLEAR TRANSLOCATION SIGNAL; P45; RAT HEPATOMA TISSUE CULTURE CELLS; SEM; SIMIAN VIRUS SV40 LARGE TUMOR ANTIGEN; SORBITOL; STANDARD ERROR OF THE MEAN; T(1/2); TAG; TEXAS RED-LABELED DEXTRAN; THE NUCLEAR TO CYTOPLASMIC RATIO; TIME TO REACH HALF-MAXIMAL RECOVERY; TR70;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; ARSENITES; CELL NUCLEUS; ENZYME ACTIVATION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; INTRACELLULAR SPACE; KARYOPHERINS; KINETICS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 8; OSMOTIC PRESSURE; PHOSPHORYLATION; PROTEIN TRANSPORT; RATS; SORBITOL; STRESS, PHYSIOLOGICAL; SUBCELLULAR FRACTIONS;

EID: 84890289987     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.10.017     Document Type: Article

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