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Volumn 557, Issue , 2013, Pages 37-42

The known knowns of microglia-neuronal signalling in neuropathic pain

Author keywords

BDNF; Microglia; P2X4; Spinal cord

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CASPASE RECRUITMENT DOMAIN PROTEIN 15; FIBRONECTIN; GAMMA INTERFERON; GLYCOPROTEIN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; POTASSIUM CHLORIDE COTRANSPORTER; PURINERGIC P2X4 RECEPTOR; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR;

EID: 84890186371     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.08.037     Document Type: Review
Times cited : (68)

References (63)
  • 1
    • 0038460075 scopus 로고    scopus 로고
    • A new view of pain as a homeostatic emotion
    • (Bud) Craig A.D. A new view of pain as a homeostatic emotion. Trends Neurosci. 2003, 26:303-307.
    • (2003) Trends Neurosci. , vol.26 , pp. 303-307
    • Craig A.D.B1
  • 3
    • 0345599886 scopus 로고    scopus 로고
    • Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn
    • Baba H., Ji R.R., Kohno T., Moore K.A., Ataka T., Wakai A., Okamoto M., Woolf C.J. Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn. Mol. Cell. Neurosci. 2003, 24:818-830.
    • (2003) Mol. Cell. Neurosci. , vol.24 , pp. 818-830
    • Baba, H.1    Ji, R.R.2    Kohno, T.3    Moore, K.A.4    Ataka, T.5    Wakai, A.6    Okamoto, M.7    Woolf, C.J.8
  • 4
    • 34249731465 scopus 로고    scopus 로고
    • Stereological and somatotopic analysis of the spinal microglial response to peripheral nerve injury
    • Beggs S., Salter M.W. Stereological and somatotopic analysis of the spinal microglial response to peripheral nerve injury. Brain Behav. Immun. 2007, 21:624-633.
    • (2007) Brain Behav. Immun. , vol.21 , pp. 624-633
    • Beggs, S.1    Salter, M.W.2
  • 5
    • 84864487226 scopus 로고    scopus 로고
    • P2X4R+ microglia drive neuropathic pain
    • Beggs S., Trang T., Salter M.W. P2X4R+ microglia drive neuropathic pain. Nat. Neurosci. 2012, 15(8):1068-1073.
    • (2012) Nat. Neurosci. , vol.15 , Issue.8 , pp. 1068-1073
    • Beggs, S.1    Trang, T.2    Salter, M.W.3
  • 8
    • 67651048942 scopus 로고    scopus 로고
    • Neuropathic pain: a maladaptive response of the nervous system to damage
    • Costigan M., Scholz J., Woolf C.J. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu. Rev. Neurosci. 2009, 32:1-32.
    • (2009) Annu. Rev. Neurosci. , vol.32 , pp. 1-32
    • Costigan, M.1    Scholz, J.2    Woolf, C.J.3
  • 11
    • 0021891175 scopus 로고
    • Spinothalamic lumbosacral lamina I cells responsive to skin and muscle stimulation in the cat
    • Craig A.D., Kniffki K.D. Spinothalamic lumbosacral lamina I cells responsive to skin and muscle stimulation in the cat. J. Physiol. 1985, 365:197-221.
    • (1985) J. Physiol. , vol.365 , pp. 197-221
    • Craig, A.D.1    Kniffki, K.D.2
  • 15
    • 77949896163 scopus 로고    scopus 로고
    • Familial pain syndromes from mutations of the NaV1.7 sodium channel
    • Fischer T.Z., Waxman S.G. Familial pain syndromes from mutations of the NaV1.7 sodium channel. Ann. N. Y. Acad. Sci. 2010, 1184:196-207.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1184 , pp. 196-207
    • Fischer, T.Z.1    Waxman, S.G.2
  • 17
    • 84857287844 scopus 로고    scopus 로고
    • Deconstructing the neuropathic pain phenotype to reveal neural mechanisms
    • von Hehn C.A., Baron R., Woolf C.J. Deconstructing the neuropathic pain phenotype to reveal neural mechanisms. Neuron 2012, 73:638-652.
    • (2012) Neuron , vol.73 , pp. 638-652
    • von Hehn, C.A.1    Baron, R.2    Woolf, C.J.3
  • 18
    • 84878153286 scopus 로고    scopus 로고
    • The prevalence and phenotype of activated microglia/macrophages within the spinal cord of the hyperostotic mouse (twy/twy) changes in response to chronic progressive spinal cord compression: implications for human cervical compressive myelopathy
    • Hirai T., Uchida K., Nakajima H., Guerrero A.R., Takeura N., Watanabe S., Sugita D., Yoshida A., Johnson W.E., Baba H. The prevalence and phenotype of activated microglia/macrophages within the spinal cord of the hyperostotic mouse (twy/twy) changes in response to chronic progressive spinal cord compression: implications for human cervical compressive myelopathy. PLoS ONE 2013, 8:e64528.
    • (2013) PLoS ONE , vol.8
    • Hirai, T.1    Uchida, K.2    Nakajima, H.3    Guerrero, A.R.4    Takeura, N.5    Watanabe, S.6    Sugita, D.7    Yoshida, A.8    Johnson, W.E.9    Baba, H.10
  • 19
    • 38049119409 scopus 로고    scopus 로고
    • P38 MAPK, microglial signaling, and neuropathic pain
    • Ji R.-R., Suter M.R. p38 MAPK, microglial signaling, and neuropathic pain. Mol. Pain 2007, 3:33.
    • (2007) Mol. Pain , vol.3 , pp. 33
    • Ji, R.-R.1    Suter, M.R.2
  • 20
    • 0037705314 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain
    • Jin S.-X., Zhuang Z.-Y., Woolf C.J., Ji R.-R. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J. Neurosci. Off. J. Soc. Neurosci. 2003, 23:4017-4022.
    • (2003) J. Neurosci. Off. J. Soc. Neurosci. , vol.23 , pp. 4017-4022
    • Jin, S.-X.1    Zhuang, Z.-Y.2    Woolf, C.J.3    Ji, R.-R.4
  • 21
    • 84859366504 scopus 로고    scopus 로고
    • Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation
    • Kaneko M., Xie Y., An J.J., Stryker M.P., Xu B. Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation. J. Neurosci. Off. J. Soc. Neurosci. 2012, 32:4790-4802.
    • (2012) J. Neurosci. Off. J. Soc. Neurosci. , vol.32 , pp. 4790-4802
    • Kaneko, M.1    Xie, Y.2    An, J.J.3    Stryker, M.P.4    Xu, B.5
  • 22
    • 33646344701 scopus 로고    scopus 로고
    • Persistent postsurgical pain: risk factors and prevention
    • Kehlet H., Jensen T.S., Woolf C.J. Persistent postsurgical pain: risk factors and prevention. Lancet 2006, 367:1618-1625.
    • (2006) Lancet , vol.367 , pp. 1618-1625
    • Kehlet, H.1    Jensen, T.S.2    Woolf, C.J.3
  • 23
    • 36549088202 scopus 로고    scopus 로고
    • Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain
    • Keller A.F., Beggs S., Salter M.W., De Koninck Y. Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain. Mol. Pain 2007, 3:27.
    • (2007) Mol. Pain , vol.3 , pp. 27
    • Keller, A.F.1    Beggs, S.2    Salter, M.W.3    De Koninck, Y.4
  • 24
    • 0037386202 scopus 로고    scopus 로고
    • Peripheral nerve injury alters excitatory synaptic transmission in lamina II of the rat dorsal horn
    • Kohno T., Moore K.A., Baba H., Woolf C.J. Peripheral nerve injury alters excitatory synaptic transmission in lamina II of the rat dorsal horn. J. Physiol. 2003, 548:131-138.
    • (2003) J. Physiol. , vol.548 , pp. 131-138
    • Kohno, T.1    Moore, K.A.2    Baba, H.3    Woolf, C.J.4
  • 25
    • 84858157952 scopus 로고    scopus 로고
    • Propentofylline, a CNS glial modulator does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages
    • Landry R.P., Jacobs V.L., Romero-Sandoval E.A., Deleo J.A. Propentofylline, a CNS glial modulator does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages. Exp. Neurol. 2012, 234(2):340-350.
    • (2012) Exp. Neurol. , vol.234 , Issue.2 , pp. 340-350
    • Landry, R.P.1    Jacobs, V.L.2    Romero-Sandoval, E.A.3    Deleo, J.A.4
  • 27
  • 29
    • 84861123981 scopus 로고    scopus 로고
    • IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype
    • Masuda T., Tsuda M., Yoshinaga R., Tozaki-Saitoh H., Ozato K., Tamura T., Inoue K. IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype. Cell Rep. 2012, 1:334-340.
    • (2012) Cell Rep. , vol.1 , pp. 334-340
    • Masuda, T.1    Tsuda, M.2    Yoshinaga, R.3    Tozaki-Saitoh, H.4    Ozato, K.5    Tamura, T.6    Inoue, K.7
  • 30
    • 40149098353 scopus 로고    scopus 로고
    • Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters from primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord
    • Merighi A., Bardoni R., Salio C., Lossi L., Ferrini F., Prandini M., Zonta M., Gustincich S., Carmignoto G. Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters from primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord. Dev. Neurobiol. 2008, 68:457-475.
    • (2008) Dev. Neurobiol. , vol.68 , pp. 457-475
    • Merighi, A.1    Bardoni, R.2    Salio, C.3    Lossi, L.4    Ferrini, F.5    Prandini, M.6    Zonta, M.7    Gustincich, S.8    Carmignoto, G.9
  • 31
    • 0031049658 scopus 로고    scopus 로고
    • Glial cell reactions in the spinal cord after sensory nerve stimulation are associated with axonal injury
    • Molander C., Hongpaisan J., Svensson M., Aldskogius H. Glial cell reactions in the spinal cord after sensory nerve stimulation are associated with axonal injury. Brain Res. 1997, 747:122-129.
    • (1997) Brain Res. , vol.747 , pp. 122-129
    • Molander, C.1    Hongpaisan, J.2    Svensson, M.3    Aldskogius, H.4
  • 32
    • 33646259685 scopus 로고    scopus 로고
    • Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X4, a key molecule for mechanical allodynia
    • Nasu-Tada K., Koizumi S., Tsuda M., Kunifusa E., Inoue K. Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X4, a key molecule for mechanical allodynia. Glia 2006, 53:769-775.
    • (2006) Glia , vol.53 , pp. 769-775
    • Nasu-Tada, K.1    Koizumi, S.2    Tsuda, M.3    Kunifusa, E.4    Inoue, K.5
  • 33
    • 0037704450 scopus 로고    scopus 로고
    • Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury
    • Obata K., Yamanaka H., Dai Y., Tachibana T., Fukuoka T., Tokunaga A., Yoshikawa H., Noguchi K. Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury. J. Neurosci. Off. J. Soc. Neurosci. 2003, 23:4117-4126.
    • (2003) J. Neurosci. Off. J. Soc. Neurosci. , vol.23 , pp. 4117-4126
    • Obata, K.1    Yamanaka, H.2    Dai, Y.3    Tachibana, T.4    Fukuoka, T.5    Tokunaga, A.6    Yoshikawa, H.7    Noguchi, K.8
  • 34
    • 42449107733 scopus 로고    scopus 로고
    • Genetic mutations that prevent pain: implications for future pain medication
    • Oertel B., Lötsch J. Genetic mutations that prevent pain: implications for future pain medication. Pharmacogenomics 2008, 9:179-194.
    • (2008) Pharmacogenomics , vol.9 , pp. 179-194
    • Oertel, B.1    Lötsch, J.2
  • 35
    • 84877086904 scopus 로고    scopus 로고
    • Analgesic efficacy and safety of the novel p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain following peripheral nerve injury: a double-blind, placebo-controlled study
    • Ostenfeld T., Krishen A., Lai R.Y., Bullman J., Baines A.J., Green J., Anand P., Kelly M. Analgesic efficacy and safety of the novel p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain following peripheral nerve injury: a double-blind, placebo-controlled study. Eur. J. Pain Lond. Engl. 2013, 17:844-857.
    • (2013) Eur. J. Pain Lond. Engl. , vol.17 , pp. 844-857
    • Ostenfeld, T.1    Krishen, A.2    Lai, R.Y.3    Bullman, J.4    Baines, A.J.5    Green, J.6    Anand, P.7    Kelly, M.8
  • 36
    • 33748375335 scopus 로고    scopus 로고
    • Neurotrophins: mediators and modulators of pain
    • Pezet S., McMahon S.B. Neurotrophins: mediators and modulators of pain. Annu. Rev. Neurosci. 2006, 29:507-538.
    • (2006) Annu. Rev. Neurosci. , vol.29 , pp. 507-538
    • Pezet, S.1    McMahon, S.B.2
  • 37
    • 36549041874 scopus 로고    scopus 로고
    • Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis
    • Qureshi O.S., Paramasivam A., Yu J.C.H., Murrell-Lagnado R.D. Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis. J. Cell Sci. 2007, 120:3838-3849.
    • (2007) J. Cell Sci. , vol.120 , pp. 3838-3849
    • Qureshi, O.S.1    Paramasivam, A.2    Yu, J.C.H.3    Murrell-Lagnado, R.D.4
  • 40
    • 35548937457 scopus 로고    scopus 로고
    • The neuropathic pain triad: neurons, immune cells and glia
    • Scholz J., Woolf C.J. The neuropathic pain triad: neurons, immune cells and glia. Nat. Neurosci. 2007, 10:1361-1368.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1361-1368
    • Scholz, J.1    Woolf, C.J.2
  • 41
    • 0037013232 scopus 로고    scopus 로고
    • Macrophage-restricted and interferon gamma-inducible expression of the allograft inflammatory factor-1 gene requires Pu.1
    • Sibinga N.E.S., Feinberg M.W., Yang H., Werner F., Jain M.K. Macrophage-restricted and interferon gamma-inducible expression of the allograft inflammatory factor-1 gene requires Pu.1. J. Biol. Chem. 2002, 277:16202-16210.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16202-16210
    • Sibinga, N.E.S.1    Feinberg, M.W.2    Yang, H.3    Werner, F.4    Jain, M.K.5
  • 42
    • 15244340126 scopus 로고    scopus 로고
    • Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization
    • Svensson C.I., Fitzsimmons B., Azizi S., Powell H.C., Hua X.-Y., Yaksh T.L. Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization. J. Neurochem. 2005, 92:1508-1520.
    • (2005) J. Neurochem. , vol.92 , pp. 1508-1520
    • Svensson, C.I.1    Fitzsimmons, B.2    Azizi, S.3    Powell, H.C.4    Hua, X.-Y.5    Yaksh, T.L.6
  • 44
    • 32544460671 scopus 로고    scopus 로고
    • Disinhibition opens the gate to pathological pain signaling in superficial neurokinin 1 receptor-expressing neurons in rat spinal cord
    • Torsney C., MacDermott A.B. Disinhibition opens the gate to pathological pain signaling in superficial neurokinin 1 receptor-expressing neurons in rat spinal cord. J. Neurosci. Off. J. Soc. Neurosci. 2006, 26:1833-1843.
    • (2006) J. Neurosci. Off. J. Soc. Neurosci. , vol.26 , pp. 1833-1843
    • Torsney, C.1    MacDermott, A.B.2
  • 45
    • 31044446583 scopus 로고    scopus 로고
    • Functional properties of internalization-deficient P2X4 receptors reveal a novel mechanism of ligand-gated channel facilitation by ivermectin
    • Toulmé E., Soto F., Garret M., Boué-Grabot E. Functional properties of internalization-deficient P2X4 receptors reveal a novel mechanism of ligand-gated channel facilitation by ivermectin. Mol. Pharmacol. 2006, 69:576-587.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 576-587
    • Toulmé, E.1    Soto, F.2    Garret, M.3    Boué-Grabot, E.4
  • 48
    • 63849192564 scopus 로고    scopus 로고
    • P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation
    • Trang T., Beggs S., Wan X., Salter M.W. P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation. J. Neurosci. Off. J. Soc. Neurosci. 2009, 29:3518-3528.
    • (2009) J. Neurosci. Off. J. Soc. Neurosci. , vol.29 , pp. 3518-3528
    • Trang, T.1    Beggs, S.2    Wan, X.3    Salter, M.W.4
  • 49
    • 67650222417 scopus 로고    scopus 로고
    • Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays
    • Tsuda M., Kuboyama K., Inoue T., Nagata K., Tozaki-Saitoh H., Inoue K. Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays. Mol. Pain 2009, 5:28.
    • (2009) Mol. Pain , vol.5 , pp. 28
    • Tsuda, M.1    Kuboyama, K.2    Inoue, T.3    Nagata, K.4    Tozaki-Saitoh, H.5    Inoue, K.6
  • 51
    • 0346655315 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury
    • Tsuda M., Mizokoshi A., Shigemoto-Mogami Y., Koizumi S., Inoue K. Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury. Glia 2004, 45:89-95.
    • (2004) Glia , vol.45 , pp. 89-95
    • Tsuda, M.1    Mizokoshi, A.2    Shigemoto-Mogami, Y.3    Koizumi, S.4    Inoue, K.5
  • 52
    • 44949248511 scopus 로고    scopus 로고
    • Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury
    • Tsuda M., Toyomitsu E., Komatsu T., Masuda T., Kunifusa E., Nasu-Tada K., Koizumi S., Yamamoto K., Ando J., Inoue K. Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury. Glia 2008, 56:579-585.
    • (2008) Glia , vol.56 , pp. 579-585
    • Tsuda, M.1    Toyomitsu, E.2    Komatsu, T.3    Masuda, T.4    Kunifusa, E.5    Nasu-Tada, K.6    Koizumi, S.7    Yamamoto, K.8    Ando, J.9    Inoue, K.10
  • 53
    • 77449099299 scopus 로고    scopus 로고
    • Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways
    • Tsuda M., Toyomitsu E., Kometani M., Tozaki-Saitoh H., Inoue K. Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways. J. Cell. Mol. Med. 2009, 13:3251-3259.
    • (2009) J. Cell. Mol. Med. , vol.13 , pp. 3251-3259
    • Tsuda, M.1    Toyomitsu, E.2    Kometani, M.3    Tozaki-Saitoh, H.4    Inoue, K.5
  • 54
    • 36448966388 scopus 로고    scopus 로고
    • Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury
    • Tsuda M., Tozaki-Saitoh H., Masuda T., Toyomitsu E., Tezuka T., Yamamoto T., Inoue K. Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury. Glia 2008, 56:50-58.
    • (2008) Glia , vol.56 , pp. 50-58
    • Tsuda, M.1    Tozaki-Saitoh, H.2    Masuda, T.3    Toyomitsu, E.4    Tezuka, T.5    Yamamoto, T.6    Inoue, K.7
  • 56
    • 84880699376 scopus 로고    scopus 로고
    • Involvement of P2X4 receptors in hippocampal microglial activation after status epilepticus
    • Ulmann L., Levavasseur F., Avignone E., Peyroutou R., Hirbec H., Audinat E., Rassendren F. Involvement of P2X4 receptors in hippocampal microglial activation after status epilepticus. Glia 2013, 61(8):1306-1319.
    • (2013) Glia , vol.61 , Issue.8 , pp. 1306-1319
    • Ulmann, L.1    Levavasseur, F.2    Avignone, E.3    Peyroutou, R.4    Hirbec, H.5    Audinat, E.6    Rassendren, F.7
  • 57
    • 36248981540 scopus 로고    scopus 로고
    • Interferon-gamma induced disruption of GABAergic inhibition in the spinal dorsal horn in vivo
    • Vikman K.S., Duggan A.W., Siddall P.J. Interferon-gamma induced disruption of GABAergic inhibition in the spinal dorsal horn in vivo. Pain 2007, 133:18-28.
    • (2007) Pain , vol.133 , pp. 18-28
    • Vikman, K.S.1    Duggan, A.W.2    Siddall, P.J.3
  • 58
    • 84862786212 scopus 로고    scopus 로고
    • Blockade of PDGFR-β activation eliminates morphine analgesic tolerance
    • Wang Y., Barker K., Shi S., Diaz M., Mo B., Gutstein H.B. Blockade of PDGFR-β activation eliminates morphine analgesic tolerance. Nat. Med. 2012, 18:385-387.
    • (2012) Nat. Med. , vol.18 , pp. 385-387
    • Wang, Y.1    Barker, K.2    Shi, S.3    Diaz, M.4    Mo, B.5    Gutstein, H.B.6
  • 59
    • 84858156759 scopus 로고    scopus 로고
    • Commentary on Landry et al.: "Propentofylline, a CNS glial modulator, does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages,"
    • Watkins L.R., Hutchinson M.R., Johnson K.W. Commentary on Landry et al.: "Propentofylline, a CNS glial modulator, does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages,". Exp. Neurol. 2012, 234(2):351-353.
    • (2012) Exp. Neurol. , vol.234 , Issue.2 , pp. 351-353
    • Watkins, L.R.1    Hutchinson, M.R.2    Johnson, K.W.3
  • 60
    • 0034625770 scopus 로고    scopus 로고
    • Neuronal plasticity: increasing the gain in pain
    • Woolf C.J., Salter M.W. Neuronal plasticity: increasing the gain in pain. Science 2000, 288:1765-1769.
    • (2000) Science , vol.288 , pp. 1765-1769
    • Woolf, C.J.1    Salter, M.W.2
  • 61
    • 0034666105 scopus 로고    scopus 로고
    • The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB
    • Xu B., Gottschalk W., Chow A., Wilson R.I., Schnell E., Zang K., Wang D., Nicoll R.A., Lu B., Reichardt L.F. The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB. J. Neurosci. Off. J. Soc. Neurosci. 2000, 20:6888-6897.
    • (2000) J. Neurosci. Off. J. Soc. Neurosci. , vol.20 , pp. 6888-6897
    • Xu, B.1    Gottschalk, W.2    Chow, A.3    Wilson, R.I.4    Schnell, E.5    Zang, K.6    Wang, D.7    Nicoll, R.A.8    Lu, B.9    Reichardt, L.F.10
  • 62
    • 84890155226 scopus 로고    scopus 로고
    • BDNF-mediated downregulation of brainstem KCC2 and cell-type specific GABA impairment for activation of descending pain facilitation
    • [Epub ahead of print]
    • Zhang Z., Wang X., Wang W., Lu Y.-G., Pan Z.Z. BDNF-mediated downregulation of brainstem KCC2 and cell-type specific GABA impairment for activation of descending pain facilitation. Mol. Pharmacol. 2013, [Epub ahead of print].
    • (2013) Mol. Pharmacol.
    • Zhang, Z.1    Wang, X.2    Wang, W.3    Lu, Y.-G.4    Pan, Z.Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.