Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X4, a key molecule for mechanical allodynia

GLIA

Volumn 53, Issue 7, 2006, Pages 769-775

  Nasu Tada, Kaoru ^a   Koizumi, Schuichi ^a   Tsuda, Makoto ^b   Kunifusa, Emiko ^b   Inoue, Kazuhide ^b  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

ATP; Extracellular matrix; Glia; Pain; Purinergic

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; FIBRONECTIN; MESSENGER RNA; PURINE P2X4 RECEPTOR;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; LUMBAR SPINAL CORD; MALE; MICROGLIA; NEWBORN; NONHUMAN; PAIN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL NERVE; UPREGULATION; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; BRAIN TISSUE TRANSPLANTATION; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; FIBRONECTINS; HYPERALGESIA; MICROGLIA; NEURALGIA; NOCICEPTORS; PERIPHERAL NERVES; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; RNA, MESSENGER; SPINAL CORD; UP-REGULATION;

EID: 33646259685     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20339     Document Type: Article

References (34)

1. Adams JC, Watt FM. 1993. Regulation of development and differentiation by the extracellular matrix. Development 117:1183-1198.
2. Cavaliere F, Florenzano F, Amadio S, Fusco FR, Viscomi MT, D'Ambrosi N, Vacca F, Sancesario G, Bernardi G, Molinari M, et al. 2003. Upregulation of P2X2, P2X4 receptor and ischemic cell death: prevention by P2 antagonists. Neuroscience 120:85-98.
3. Farooque M, Zhang Y, Holtz A, Olsson Y. 1992. Exudation of fibronectin and albumin after spinal cord injury in rats. Acta Neuropathol (Berl) 84:613-620.
4. Hoke A, Silver J. 1996. Proteoglycans and other repulsive molecules in glial boundaries during development and regeneration of the nervous system. Prog Brain Res 108:149-163.
5. Hynes RO. 1992. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69:11-25.
6. Inoue K. 2002. Microglial activation by purines and pyrimidines. Glia 40:156-163.
7. Jiang B, Liou GI, Behzadian MA, Caldwell RB. 1994. Astrocytes modulate retinal vasculogenesis: effects on fibronectin expression. J Cell Sci 107:2499-2508.
8. Jones LS. 1996. Integrins: possible functions in the adult CNS. Trends Neurosci 19:68-72.
9. Krolo M, Vilovic K, Sapunar D, Vrdoljak E, Saraga-Babic M. 1998. Fibronectin expression in the developing human spinal cord, nerves, and ganglia. Croat Med J 39:386-391.
10. Le KT, Babinski K, Seguela P. 1998. Central P2X4 and P2X6 channel subunits coassemble into a novel heteromeric ATP receptor. J Neurosci 18:7152-7159.
11. Lefcort F, Venstrom K, McDonald JA, Reichardt LF. 1992. Regulation of expression of fibronectin and its receptor, alpha 5 beta 1, during development and regeneration of peripheral nerve. Development 116:767-782.
12. Martini R. 1994. Expression and functional roles of neural cell surface molecules and extracellular matrix components during development and regeneration of peripheral nerves. J Neurocytol 23:1-28.
13. Matthiessen HP, Schmalenbach C, Muller HW. 1989. Astroglia-released neurite growth-inducing activity for embryonic hippocampal neurons is associated with laminin bound in a sulfated complex and free fibronectin. Glia 2:177-188.
14. Milner R, Campbell IL. 2002. Cytokines regulate microglial adhesion to laminin and astrocyte extracellular matrix via protein kinase C-dependent activation of the alpha6beta1 integrin. J Neurosci 22:1562-1572.
15. Milner R, Campbell IL. 2003. The extracellular matrix and cytokines regulate microglial integrin expression and activation. J Immunol 170:3850-3858.
16. Nag S, Picard P, Stewart DJ. 2001. Expression of nitric oxide synthases and nitrotyrosine during blood-brain barrier breakdown and repair after cold injury. Lab Invest 81:41-49.
17. Nakajima K, Shimojo M, Hamanoue M, Ishiura S, Sugita H, Kohsaka S. 1992. Identification of elastase as a secretory protease from cultured rat microglia. J Neurochem 58:1401-1408.
18. Nasu-Tada K, Koizumi S, Inoue K. 2005. Involvement of beta1 integrin in microglial chemotaxis and proliferation on fibronectin: different regulations by ADP through PKA. Glia 52:98-107.
19. Nourhaghighi N, Teichert-Kuliszewska K, Davis J, Stewart DJ, Nag S. 2003. Altered expression of angiopoietins during blood-brain barrier breakdown and angiogenesis. Lab Invest 83:1211-1222.
20. Pasinetti GM, Nichols NR, Tocco G, Morgan T, Laping N, Finch CE. 1993. Transforming growth factor beta 1 and fibronectin messenger RNA in rat brain: responses to injury and cell-type localization. Neuroscience 54:893-907.
21. Price J, Hynes RO. 1985. Astrocytes in culture synthesize and secrete a variant form of fibronectin. J Neurosci 5:2205-2211.
22. Raghow R. 1994. The role of extracellular matrix in postinflammatory wound healing and fibrosis. Faseb J 8:823-831.
23. Ralevic V, Burnstock G. 1998. Receptors for purines and pyrimidines. Pharmacol Rev 50:413-492.
24. Sakai T, Johnson KJ, Murozono M, Sakai K, Magnuson MA, Wieloch T, Cronberg T, Isshiki A, Erickson HP, Fassler R. 2001. Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. Nat Med 7:324-330.
25. Sasaki Y, Hoshi M, Akazawa C, Nakamura Y, Tsuzuki H, Inoue K, Kohsaka S. 2003. Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain. Glia 44:242-250.
26. Soto F, Garcia-Guzman M, Gomez-Hernandez JM, Hollmann M, Karschin C, Stuhmer W. 1996. P2X4: an ATP-activated ionotropic receptor cloned from rat brain. Proc Natl Acad Sci USA 93:3684-3688.
27. Thompson PN, Cho E, Blumenstock FA, Shah DM, Saba TM. 1992. Rebound elevation of fibronectin after tissue injury and ischemia: role of fibronectin synthesis. Am J Physiol 263:G437-G445.
28. Tom VJ, Doller CM, Malouf AT, Silver J. 2004. Astrocyte-associated fibronectin is critical for axonal regeneration in adult white matter. J Neurosci 24:9282-9290.
29. Tsuda M, Inoue K, Salter MW. 2005. Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia. Trends Neurosci 28:101-107.
30. Tsuda M, Shigemoto-Mogami Y, Koizumi S, Mizokoshi A, Kohsaka S, Salter MW, Inoue K. 2003. P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature 424:778-783.
31. Venstrom KA, Reichardt LF. 1993. Extracellular matrix. 2: Role of extracellular matrix molecules and their receptors in the nervous system. Faseb J 7:996-1003.
32. Vogelezang MG, Scherer SS, Fawcett JW, ffrench-Constant C. 1999. Regulation of fibronectin alternative splicing during peripheral nerve repair. J Neurosci Res 56:323-333.
33. Yeung D, Kharidia R, Brown SC, Gorecki DC. 2004. Enhanced expression of the P2X4 receptor in Duchenne muscular dystrophy correlates with macrophage invasion. Neurobiol Dis 15:212-220.
34. Zhang FL, Luo L, Gustafson E, Palmer K, Qiao X, Fan X, Yang S, Laz TM, Bayne M, Monsma F, Jr. 2002. P2Y(13): identification and characterization of a novel Galphai-coupled ADP receptor from human and mouse. J Pharmacol Exp Ther 301:705-713.