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Volumn 30, Issue 4, 2013, Pages 298-312

The role of molecular analyses in the diagnosis and treatment of non-small-cell lung carcinomas

Author keywords

ALK; EGFR; Immunohistochemistry; Lung; NSCLC

Indexed keywords

ANAPLASTIC LYMPHOMA RECEPTOR TYROSINE KINASE INHIBITOR; B RAF KINASE; CISPLATIN; CRIZOTINIB; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; GEMCITABINE; PEMETREXED; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 84890148104     PISSN: 07402570     EISSN: 19301111     Source Type: Journal    
DOI: 10.1053/j.semdp.2013.11.007     Document Type: Article
Times cited : (15)

References (143)
  • 2
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
    • Scagliotti G.V., Parikh P., von Pawel J., et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 2008, 26(21):3543-3551.
    • (2008) J Clin Oncol , vol.26 , Issue.21 , pp. 3543-3551
    • Scagliotti, G.V.1    Parikh, P.2    von Pawel, J.3
  • 3
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small cell lung cancer to gefitinib
    • Lynch T.J., Bell D.W., Sordella R., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small cell lung cancer to gefitinib. N Engl J Med 2004, 350(21):2129-2139.
    • (2004) N Engl J Med , vol.350 , Issue.21 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 4
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
    • Paez J.G., Jänne P.A., Lee J.C., et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004, 304(5676):1497-1500.
    • (2004) Science , vol.304 , Issue.5676 , pp. 1497-1500
    • Paez, J.G.1    Jänne, P.A.2    Lee, J.C.3
  • 5
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W., Miller V., Zakowski M., et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004, 101(36):13306-13311.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.36 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 6
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok T.S., Wu Y.L., Thongprasert S., et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009, 361(10):947-957.
    • (2009) N Engl J Med , vol.361 , Issue.10 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 7
    • 75249087060 scopus 로고    scopus 로고
    • Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
    • Mitsudomi T., Morita S., Yatabe Y., et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010, 11(2):121-128.
    • (2010) Lancet Oncol , vol.11 , Issue.2 , pp. 121-128
    • Mitsudomi, T.1    Morita, S.2    Yatabe, Y.3
  • 8
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
    • Maemondo M., Inoue A., Kobayashi K., et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010, 362(25):2380-2388.
    • (2010) N Engl J Med , vol.362 , Issue.25 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3
  • 9
    • 76749154617 scopus 로고    scopus 로고
    • Randomized phase III trial of gefitinib versus docetaxel in non-small cell lung cancer patients who have previously received platinum-based chemotherapy
    • Lee D.H., Park K., Kim J.H., et al. Randomized phase III trial of gefitinib versus docetaxel in non-small cell lung cancer patients who have previously received platinum-based chemotherapy. Clin Cancer Res 2010, 16(4):1307-1314.
    • (2010) Clin Cancer Res , vol.16 , Issue.4 , pp. 1307-1314
    • Lee, D.H.1    Park, K.2    Kim, J.H.3
  • 10
    • 79960889662 scopus 로고    scopus 로고
    • Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study
    • Zhou C., Wu Y.L., Chen G., et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011, 12(8):735-742.
    • (2011) Lancet Oncol , vol.12 , Issue.8 , pp. 735-742
    • Zhou, C.1    Wu, Y.L.2    Chen, G.3
  • 11
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
    • Rosell R., Carcereny E., Gervais R., et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012, 13(3):239-246.
    • (2012) Lancet Oncol , vol.13 , Issue.3 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3
  • 12
    • 79957492069 scopus 로고    scopus 로고
    • American Society of Clinical Oncology provisional clinical opinion: epidermal growth factor receptor (EGFR) mutation testing for patients with advanced non-small-cell lung cancer considering first-line EGFR tyrosine kinase inhibitor therapy
    • Keedy V.L., Temin S., Somerfield M.R., et al. American Society of Clinical Oncology provisional clinical opinion: epidermal growth factor receptor (EGFR) mutation testing for patients with advanced non-small-cell lung cancer considering first-line EGFR tyrosine kinase inhibitor therapy. J Clin Oncol 2011, 29(15):2121-2127.
    • (2011) J Clin Oncol , vol.29 , Issue.15 , pp. 2121-2127
    • Keedy, V.L.1    Temin, S.2    Somerfield, M.R.3
  • 13
    • 77954321859 scopus 로고    scopus 로고
    • Metastatic non-small-cell lung cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
    • D'Addario G., Früh M., Reck M., et al. Metastatic non-small-cell lung cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010, 21(suppl 5):v116-v1199.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 5
    • D'Addario, G.1    Früh, M.2    Reck, M.3
  • 14
    • 84866655838 scopus 로고    scopus 로고
    • LUX-Lung 3: a randomized, open-label, phase III study of afatinib versus pemetrexed and cisplatin as first-line treatment for patients with advanced adenocarcinoma of the lung harboring EGFR-activating mutations
    • [suppl; abstr LBA7500]
    • Yang J.C., Schuler M.H., Yamamoto N., et al. LUX-Lung 3: a randomized, open-label, phase III study of afatinib versus pemetrexed and cisplatin as first-line treatment for patients with advanced adenocarcinoma of the lung harboring EGFR-activating mutations. J Clin Oncol 2012, 30. [suppl; abstr LBA7500].
    • (2012) J Clin Oncol , vol.30
    • Yang, J.C.1    Schuler, M.H.2    Yamamoto, N.3
  • 15
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • Soda M., Choi Y.L., Enomoto M., et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007, 448(7153):561-566.
    • (2007) Nature , vol.448 , Issue.7153 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3
  • 16
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak E.L., Bang Y.J., Camidge D.R., et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 2010, 363(18):1693-1703.
    • (2010) N Engl J Med , vol.363 , Issue.18 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 18
    • 65349107082 scopus 로고    scopus 로고
    • KRAS mutations in non-small cell lung cancer
    • Riely G.J., Marks J., Pao W. KRAS mutations in non-small cell lung cancer. Proc Am Thorac Soc 2009, 6(2):201-205.
    • (2009) Proc Am Thorac Soc , vol.6 , Issue.2 , pp. 201-205
    • Riely, G.J.1    Marks, J.2    Pao, W.3
  • 19
    • 33750700477 scopus 로고    scopus 로고
    • Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study
    • Giaccone G., Gallegos Ruiz M., Le Chevalier T., et al. Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study. Clin Cancer Res 2006, 12(20):6049-6055.
    • (2006) Clin Cancer Res , vol.12 , Issue.20 , pp. 6049-6055
    • Giaccone, G.1    Gallegos Ruiz, M.2    Le Chevalier, T.3
  • 20
    • 33947504732 scopus 로고    scopus 로고
    • Phase II clinical trial of chemotherapy-naive patients ≥70 years of age treated with erlotinib for advanced non-small-cell lung cancer
    • Jackman D.M., Yeap B.Y., Lindeman N.I., et al. Phase II clinical trial of chemotherapy-naive patients ≥70 years of age treated with erlotinib for advanced non-small-cell lung cancer. J Clin Oncol 2007, 25(7):760-766.
    • (2007) J Clin Oncol , vol.25 , Issue.7 , pp. 760-766
    • Jackman, D.M.1    Yeap, B.Y.2    Lindeman, N.I.3
  • 21
    • 18244371651 scopus 로고    scopus 로고
    • Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
    • Pao W., Miller V.A., Politi K.A., et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005, 2(3):e73.
    • (2005) PLoS Med , vol.2 , Issue.3
    • Pao, W.1    Miller, V.A.2    Politi, K.A.3
  • 22
    • 15744372810 scopus 로고    scopus 로고
    • KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
    • Pao W., Wang T.Y., Riely G.J., et al. KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2005, 2(1):e17.
    • (2005) PLoS Med , vol.2 , Issue.1
    • Pao, W.1    Wang, T.Y.2    Riely, G.J.3
  • 23
    • 34249810645 scopus 로고    scopus 로고
    • KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
    • Massarelli E., Varella-Garcia M., Tang X., et al. KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin Cancer Res 2007, 13(10):2890-2896.
    • (2007) Clin Cancer Res , vol.13 , Issue.10 , pp. 2890-2896
    • Massarelli, E.1    Varella-Garcia, M.2    Tang, X.3
  • 24
    • 52749099497 scopus 로고    scopus 로고
    • Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
    • Linardou H., Dahabreh I.J., Kanaloupiti D., et al. Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol 2008, 9(10):962-972.
    • (2008) Lancet Oncol , vol.9 , Issue.10 , pp. 962-972
    • Linardou, H.1    Dahabreh, I.J.2    Kanaloupiti, D.3
  • 25
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small cell lung cancer
    • Shepherd F.A., Rodrigues Pereira J., Ciuleanu T., et al. Erlotinib in previously treated non-small cell lung cancer. N Engl J Med 2006, 353(2):123-132.
    • (2006) N Engl J Med , vol.353 , Issue.2 , pp. 123-132
    • Shepherd, F.A.1    Rodrigues Pereira, J.2    Ciuleanu, T.3
  • 26
    • 77949886293 scopus 로고    scopus 로고
    • Analysis of potential predictive markers of cetuximab benefit in BMS099, a phase III study of cetuximab and first-line taxane/carboplatin in advanced non-small-cell lung cancer
    • Khambata-Ford S., Harbison C.T., Hart L.L., et al. Analysis of potential predictive markers of cetuximab benefit in BMS099, a phase III study of cetuximab and first-line taxane/carboplatin in advanced non-small-cell lung cancer. J Clin Oncol 2010, 28(6):918-927.
    • (2010) J Clin Oncol , vol.28 , Issue.6 , pp. 918-927
    • Khambata-Ford, S.1    Harbison, C.T.2    Hart, L.L.3
  • 27
    • 79960894047 scopus 로고    scopus 로고
    • Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study
    • O'Byrne K.J., Gatzemeier U., Bondarenko I., et al. Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study. Lancet Oncol 2011, 12(8):795-805.
    • (2011) Lancet Oncol , vol.12 , Issue.8 , pp. 795-805
    • O'Byrne, K.J.1    Gatzemeier, U.2    Bondarenko, I.3
  • 28
    • 0038362742 scopus 로고    scopus 로고
    • Phase II study of the farnesyl transferase inhibitor R115777 in patients with advanced non-small-cell lung cancer
    • Adjei A.A., Mauer A., Bruzek L., et al. Phase II study of the farnesyl transferase inhibitor R115777 in patients with advanced non-small-cell lung cancer. J Clin Oncol 2003, 21(9):1760-1766.
    • (2003) J Clin Oncol , vol.21 , Issue.9 , pp. 1760-1766
    • Adjei, A.A.1    Mauer, A.2    Bruzek, L.3
  • 29
    • 84890195479 scopus 로고    scopus 로고
    • A phase II study of efficacy and tolerability of the farnesyl-protein transferase inhibitor L-778123 as first-line therapy in patients with advanced non-small cell lung cancer (NSCLC). ASCO Meeting Abstracts
    • Evans TL, Fidias P, Skarin A. A phase II study of efficacy and tolerability of the farnesyl-protein transferase inhibitor L-778123 as first-line therapy in patients with advanced non-small cell lung cancer (NSCLC). ASCO Meeting Abstracts. 2 (13); 2002.
    • (2002) , vol.2 , Issue.13
    • Evans, T.L.1    Fidias, P.2    Skarin, A.3
  • 30
    • 22544467757 scopus 로고    scopus 로고
    • Phase II study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in patients with taxane-refractory/resistant nonsmall cell lung carcinoma
    • Kim E.S., Kies M.S., Fossella F.V., et al. Phase II study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in patients with taxane-refractory/resistant nonsmall cell lung carcinoma. Cancer 2005, 104(3):561-569.
    • (2005) Cancer , vol.104 , Issue.3 , pp. 561-569
    • Kim, E.S.1    Kies, M.S.2    Fossella, F.V.3
  • 31
    • 80051974548 scopus 로고    scopus 로고
    • Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer
    • Sequist L.V., von Pawel J., Garmey E.G., et al. Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer. J Clin Oncol 2011, 29(24):3307-3315.
    • (2011) J Clin Oncol , vol.29 , Issue.24 , pp. 3307-3315
    • Sequist, L.V.1    von Pawel, J.2    Garmey, E.G.3
  • 32
    • 78650034175 scopus 로고    scopus 로고
    • Genetically informed lung cancer medicine
    • Pao W., Iafrate J.A., Su Z. Genetically informed lung cancer medicine. J Pathol 2011, 223(2):230-240.
    • (2011) J Pathol , vol.223 , Issue.2 , pp. 230-240
    • Pao, W.1    Iafrate, J.A.2    Su, Z.3
  • 33
    • 79953118839 scopus 로고    scopus 로고
    • Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
    • Sequist L.V., Waltman B.A., Dias-Santagata D., et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med 2011, 3(75):75ra26.
    • (2011) Sci Transl Med , vol.3 , Issue.75
    • Sequist, L.V.1    Waltman, B.A.2    Dias-Santagata, D.3
  • 34
    • 79251490374 scopus 로고    scopus 로고
    • New driver mutations in non-small-cell lung cancer
    • Pao W., Girard N. New driver mutations in non-small-cell lung cancer. Lancet Oncol 2011, 12(2):175-180.
    • (2011) Lancet Oncol , vol.12 , Issue.2 , pp. 175-180
    • Pao, W.1    Girard, N.2
  • 35
    • 79551563284 scopus 로고    scopus 로고
    • International association for the study of lung cancer/American Thoracic Society/European Respiratory Society International multidisciplinary classification of lung adenocarcinoma
    • Travis W.D., Brambilla E., Noguchi M., et al. International association for the study of lung cancer/American Thoracic Society/European Respiratory Society International multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 2011, 6(2):244-285.
    • (2011) J Thorac Oncol , vol.6 , Issue.2 , pp. 244-285
    • Travis, W.D.1    Brambilla, E.2    Noguchi, M.3
  • 36
    • 77951159184 scopus 로고    scopus 로고
    • Lung cancer: multidisciplinary approach for management
    • Brambilla E. Lung cancer: multidisciplinary approach for management. Eur Respir J 2010, 35(4):717-720.
    • (2010) Eur Respir J , vol.35 , Issue.4 , pp. 717-720
    • Brambilla, E.1
  • 37
    • 84857087591 scopus 로고    scopus 로고
    • Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations
    • Rekhtman N., Paik P.K., Arcila M.E., et al. Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations. Clin Cancer Res 2012, 18(4):1167-1176.
    • (2012) Clin Cancer Res , vol.18 , Issue.4 , pp. 1167-1176
    • Rekhtman, N.1    Paik, P.K.2    Arcila, M.E.3
  • 38
    • 20044364933 scopus 로고    scopus 로고
    • EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
    • Marchetti A., Martella C., Felicioni L., et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol 2005, 23(4):57-65.
    • (2005) J Clin Oncol , vol.23 , Issue.4 , pp. 57-65
    • Marchetti, A.1    Martella, C.2    Felicioni, L.3
  • 39
    • 80053014471 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with nonsmall-cell lung cancer harboring BRAF mutations
    • Marchetti A., Felicioni L., Malatesta S., et al. Clinical features and outcome of patients with nonsmall-cell lung cancer harboring BRAF mutations. J Clin Oncol 2011, 29(26):3574-3579.
    • (2011) J Clin Oncol , vol.29 , Issue.26 , pp. 3574-3579
    • Marchetti, A.1    Felicioni, L.2    Malatesta, S.3
  • 40
    • 84863338079 scopus 로고    scopus 로고
    • ROS1 rearrangements define a unique molecular class of lung cancers
    • Bergethon K., Shaw A.T., Ou S.H.I., et al. ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol 2012, 30(8):863-870.
    • (2012) J Clin Oncol , vol.30 , Issue.8 , pp. 863-870
    • Bergethon, K.1    Shaw, A.T.2    Ou, S.H.I.3
  • 41
    • 84860532031 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the lung: molecular subtypes and therapeutic opportunities
    • Perez-Moreno P., Brambilla E., Roman Thomas, Soria J.C. Squamous cell carcinoma of the lung: molecular subtypes and therapeutic opportunities. Clin Cancer Res 2012, 18(9):1-9.
    • (2012) Clin Cancer Res , vol.18 , Issue.9 , pp. 1-9
    • Perez-Moreno, P.1    Brambilla, E.2    Roman, T.3    Soria, J.C.4
  • 42
    • 84856823963 scopus 로고    scopus 로고
    • Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling
    • Chaft J.E., Arcila M.E., Paik P.K., et al. Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling. Mol Cancer Ther 2012, 11(2):485-491.
    • (2012) Mol Cancer Ther , vol.11 , Issue.2 , pp. 485-491
    • Chaft, J.E.1    Arcila, M.E.2    Paik, P.K.3
  • 43
    • 80055074897 scopus 로고    scopus 로고
    • Histopathologic characteristics of lung adenocarcinomas with epidermal growth factor receptor mutations in the International Association for the study of Lung Cancer/American Thoracic Society/European Respiratory Society lung adenocarcinoma classification
    • Shim H.S., Lee D.H., Park E.J., Kim S.H. Histopathologic characteristics of lung adenocarcinomas with epidermal growth factor receptor mutations in the International Association for the study of Lung Cancer/American Thoracic Society/European Respiratory Society lung adenocarcinoma classification. Arch Pathol Lab Med 2011, 135(10):1329-1334.
    • (2011) Arch Pathol Lab Med , vol.135 , Issue.10 , pp. 1329-1334
    • Shim, H.S.1    Lee, D.H.2    Park, E.J.3    Kim, S.H.4
  • 44
    • 54549094903 scopus 로고    scopus 로고
    • Somatic mutations affect key pathways in lung adenocarcinoma
    • Ding L., Getz G., Wheeler D.A., et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature 2008, 455(7216):1069-1075.
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1069-1075
    • Ding, L.1    Getz, G.2    Wheeler, D.A.3
  • 45
    • 46249096082 scopus 로고    scopus 로고
    • Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes, EGFR mutations and gene expression analysis
    • Motoi N., Szoke J., Riely G.J., et al. Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes, EGFR mutations and gene expression analysis. Am J Surg Pathol 2008, 32(6):810-827.
    • (2008) Am J Surg Pathol , vol.32 , Issue.6 , pp. 810-827
    • Motoi, N.1    Szoke, J.2    Riely, G.J.3
  • 46
    • 41149097557 scopus 로고    scopus 로고
    • Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib
    • Miller V.A., Riely G.J., Zakowski M.F., et al. Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib. J Clin Oncol 2008, 26(9):1472-1478.
    • (2008) J Clin Oncol , vol.26 , Issue.9 , pp. 1472-1478
    • Miller, V.A.1    Riely, G.J.2    Zakowski, M.F.3
  • 47
    • 65349167234 scopus 로고    scopus 로고
    • EGFR and K-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to EGFR inhibitors
    • Sartori G., Cavazza A., Sgambato A., et al. EGFR and K-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to EGFR inhibitors. Am J Clin Pathol 2009, 131(4):478-489.
    • (2009) Am J Clin Pathol , vol.131 , Issue.4 , pp. 478-489
    • Sartori, G.1    Cavazza, A.2    Sgambato, A.3
  • 48
    • 80052481361 scopus 로고    scopus 로고
    • Clinicopathological features of lung adenocarcinoma with KRAS mutations
    • Kakegawa S., Shimizu K., Sugano M., et al. Clinicopathological features of lung adenocarcinoma with KRAS mutations. Cancer 2011, 117(18):4257-4266.
    • (2011) Cancer , vol.117 , Issue.18 , pp. 4257-4266
    • Kakegawa, S.1    Shimizu, K.2    Sugano, M.3
  • 49
    • 77349091545 scopus 로고    scopus 로고
    • Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation
    • Suda K., Tomizawa K., Mitsudomi T. Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation. Cancer Metastasis Rev 2010, 29(1):49-60.
    • (2010) Cancer Metastasis Rev , vol.29 , Issue.1 , pp. 49-60
    • Suda, K.1    Tomizawa, K.2    Mitsudomi, T.3
  • 51
    • 9444260917 scopus 로고    scopus 로고
    • Bronchioloalveolar lung carcinomas: K-ras mutations are constant events in the mucinous subtype
    • Marchetti A., Buttitta F., Pellegrini S., et al. Bronchioloalveolar lung carcinomas: K-ras mutations are constant events in the mucinous subtype. J Pathol 1996, 179(3):254-259.
    • (1996) J Pathol , vol.179 , Issue.3 , pp. 254-259
    • Marchetti, A.1    Buttitta, F.2    Pellegrini, S.3
  • 52
    • 0036895599 scopus 로고    scopus 로고
    • Missense mutations of the BRAF gene in human lung adenocarcinoma
    • Naoki K., Chen T.H., Richards W.G., et al. Missense mutations of the BRAF gene in human lung adenocarcinoma. Cancer Res 2002, 62(23):7001-7003.
    • (2002) Cancer Res , vol.62 , Issue.23 , pp. 7001-7003
    • Naoki, K.1    Chen, T.H.2    Richards, W.G.3
  • 53
    • 33750627353 scopus 로고    scopus 로고
    • Mutational analysis of the HER2 gene in lung tumors from Caucasian patients: mutations are mainly present in adenocarcinomas with bronchioloalveolar features
    • Buttitta F., Barassi F., Fresu G., et al. Mutational analysis of the HER2 gene in lung tumors from Caucasian patients: mutations are mainly present in adenocarcinomas with bronchioloalveolar features. Int J Cancer 2006, 119(11):2586-2591.
    • (2006) Int J Cancer , vol.119 , Issue.11 , pp. 2586-2591
    • Buttitta, F.1    Barassi, F.2    Fresu, G.3
  • 54
    • 37549060017 scopus 로고    scopus 로고
    • EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
    • Inamura K., Takeuchi K., Togashi Y., et al. EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 2008, 3(1):13-17.
    • (2008) J Thorac Oncol , vol.3 , Issue.1 , pp. 13-17
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3
  • 55
    • 69349083935 scopus 로고    scopus 로고
    • Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
    • Rodig S.J., Mino-Kenudson M., Dacic S., et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res 2009, 15(16):5216-5223.
    • (2009) Clin Cancer Res , vol.15 , Issue.16 , pp. 5216-5223
    • Rodig, S.J.1    Mino-Kenudson, M.2    Dacic, S.3
  • 56
    • 79961099514 scopus 로고    scopus 로고
    • Comprehensive histologic analysis of ALK-rearranged lung carcinomas
    • Yoshida A., Tsuta K., Nakamura H., et al. Comprehensive histologic analysis of ALK-rearranged lung carcinomas. Am J Surg Pathol 2011, 35(8):1226-1234.
    • (2011) Am J Surg Pathol , vol.35 , Issue.8 , pp. 1226-1234
    • Yoshida, A.1    Tsuta, K.2    Nakamura, H.3
  • 57
    • 79955467025 scopus 로고    scopus 로고
    • Frequent ALK rearrangement and TTF-1/p63 co-expression in lung adenocarcinoma with signet-ring cell component
    • Yoshida A., Tsuta K., Watanabe S., et al. Frequent ALK rearrangement and TTF-1/p63 co-expression in lung adenocarcinoma with signet-ring cell component. Lung Cancer 2011, 72(3):309-315.
    • (2011) Lung Cancer , vol.72 , Issue.3 , pp. 309-315
    • Yoshida, A.1    Tsuta, K.2    Watanabe, S.3
  • 58
    • 52149114884 scopus 로고    scopus 로고
    • The histopathology of BRAF-V600E-mutated lung adenocarcinoma
    • Yousem S.A., Nikiforova M., Nikiforov Y. The histopathology of BRAF-V600E-mutated lung adenocarcinoma. Am J Surg Pathol 2008, 32(9):1317-1321.
    • (2008) Am J Surg Pathol , vol.32 , Issue.9 , pp. 1317-1321
    • Yousem, S.A.1    Nikiforova, M.2    Nikiforov, Y.3
  • 59
    • 79956316170 scopus 로고    scopus 로고
    • Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations
    • Paik P.K., Arcila M.E., Fara M., et al. Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. J Clin Oncol 2011, 29(15):2046-2051.
    • (2011) J Clin Oncol , vol.29 , Issue.15 , pp. 2046-2051
    • Paik, P.K.1    Arcila, M.E.2    Fara, M.3
  • 60
    • 65349111219 scopus 로고    scopus 로고
    • Micropapillary lung adenocarcinoma: EGFR, KRAS, and BRAF mutational profile
    • De Oliveira Duarte Achcar R., Nikiforova M.N., Yousem S.A. Micropapillary lung adenocarcinoma: EGFR, KRAS, and BRAF mutational profile. Am J Clin Pathol 2009, 131(5):694-700.
    • (2009) Am J Clin Pathol , vol.131 , Issue.5 , pp. 694-700
    • De Oliveira Duarte Achcar, R.1    Nikiforova, M.N.2    Yousem, S.A.3
  • 61
    • 80052558779 scopus 로고    scopus 로고
    • Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancer
    • Tomizawa K., Suda K., Onozato R., et al. Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancer. Lung Cancer 2011, 74(1):139-144.
    • (2011) Lung Cancer , vol.74 , Issue.1 , pp. 139-144
    • Tomizawa, K.1    Suda, K.2    Onozato, R.3
  • 62
    • 8444240380 scopus 로고    scopus 로고
    • Dominant papillary subtype is a significant predictor of the response to gefitinib in adenocarcinoma of the lung
    • Kim Y.H., Ishii G., Goto K., et al. Dominant papillary subtype is a significant predictor of the response to gefitinib in adenocarcinoma of the lung. Clin Cancer Res 2004, 10(21):7311-7317.
    • (2004) Clin Cancer Res , vol.10 , Issue.21 , pp. 7311-7317
    • Kim, Y.H.1    Ishii, G.2    Goto, K.3
  • 63
    • 84860555192 scopus 로고    scopus 로고
    • Role of molecular studies in the diagnosis of lung adenocarcinoma
    • Yousem S.A. Role of molecular studies in the diagnosis of lung adenocarcinoma. Mod Pathol 2012, 25(Suppl 1):S11-S17.
    • (2012) Mod Pathol , vol.25 , Issue.SUPPL 1
    • Yousem, S.A.1
  • 64
    • 2642567642 scopus 로고    scopus 로고
    • CK20 expression, CDX2 expression, K-ras mutations, and goblet cell morphology in a subset of lung adenocarcinoma
    • Yatabe Y., Koga T., Mitsudomi T., et al. CK20 expression, CDX2 expression, K-ras mutations, and goblet cell morphology in a subset of lung adenocarcinoma. J Pathol 2004, 203(2):645-652.
    • (2004) J Pathol , vol.203 , Issue.2 , pp. 645-652
    • Yatabe, Y.1    Koga, T.2    Mitsudomi, T.3
  • 65
    • 34548182258 scopus 로고    scopus 로고
    • Mucinous differentiation correlates with absence of EGFR mutations and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features
    • Finberg K.E., Sequist L.V., Joshi V.A., et al. Mucinous differentiation correlates with absence of EGFR mutations and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features. J Mol Diagn 2007, 9(3):320-326.
    • (2007) J Mol Diagn , vol.9 , Issue.3 , pp. 320-326
    • Finberg, K.E.1    Sequist, L.V.2    Joshi, V.A.3
  • 66
    • 17744371335 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutation is specific for terminal respiratory type adenocarcinoma
    • Yatabe Y., Kosaka T., Takahashi T., et al. Epidermal growth factor receptor mutation is specific for terminal respiratory type adenocarcinoma. Am J Surg Pathol 2005, 29(15):633-639.
    • (2005) Am J Surg Pathol , vol.29 , Issue.15 , pp. 633-639
    • Yatabe, Y.1    Kosaka, T.2    Takahashi, T.3
  • 67
    • 80053570615 scopus 로고    scopus 로고
    • Immunohistochemical algorithm for differentiation of lung adenocarcinoma and squamous cell carcinoma based on large series of whole-tissue sections with validation in small specimens
    • Rekhtman N., Ang D.C., Sima C.S., Travis W.D., Moreira A.L. Immunohistochemical algorithm for differentiation of lung adenocarcinoma and squamous cell carcinoma based on large series of whole-tissue sections with validation in small specimens. Mod Pathol 2011, 24(10):1348-1359.
    • (2011) Mod Pathol , vol.24 , Issue.10 , pp. 1348-1359
    • Rekhtman, N.1    Ang, D.C.2    Sima, C.S.3    Travis, W.D.4    Moreira, A.L.5
  • 68
    • 78650862148 scopus 로고    scopus 로고
    • Subclassification of non-small cell lung carcinomas lacking morphologic differentiation on biopsy specimens: utility of an immunohistochemical panel containing TTF-1, napsin A, p63, and CK5/6
    • Mukhopadhyay S., Katzenstein A.L. Subclassification of non-small cell lung carcinomas lacking morphologic differentiation on biopsy specimens: utility of an immunohistochemical panel containing TTF-1, napsin A, p63, and CK5/6. Am J Surg Pathol 2011, 35(1):15-25.
    • (2011) Am J Surg Pathol , vol.35 , Issue.1 , pp. 15-25
    • Mukhopadhyay, S.1    Katzenstein, A.L.2
  • 69
    • 79960674310 scopus 로고    scopus 로고
    • Immunohistochemical subtyping of nonsmall cell lung cancer not otherwise specified in fine-needle aspiration cytology: a retrospective study of 103 cases with surgical correlation
    • Righi L., Graziano P., Fornari A., et al. Immunohistochemical subtyping of nonsmall cell lung cancer not otherwise specified in fine-needle aspiration cytology: a retrospective study of 103 cases with surgical correlation. Cancer 2011, 117(15):3416-3423.
    • (2011) Cancer , vol.117 , Issue.15 , pp. 3416-3423
    • Righi, L.1    Graziano, P.2    Fornari, A.3
  • 70
    • 84858342603 scopus 로고    scopus 로고
    • D (delta)Np63 (p40) and thyroid transcription factor-1 (TTF1) immunoreactivity upon small biopsies or cell blocks for typing non-small cell lung cancer: a novel two-hit, sparing-material approach
    • Pelosi G., Fabbri A., Bianchi F., et al. D (delta)Np63 (p40) and thyroid transcription factor-1 (TTF1) immunoreactivity upon small biopsies or cell blocks for typing non-small cell lung cancer: a novel two-hit, sparing-material approach. J Thorac Oncol 2012, 7(2):281-290.
    • (2012) J Thorac Oncol , vol.7 , Issue.2 , pp. 281-290
    • Pelosi, G.1    Fabbri, A.2    Bianchi, F.3
  • 72
    • 84860589522 scopus 로고    scopus 로고
    • Update on small cell carcinoma and its differentiation from squamous cell carcinoma and other non-small cell carcinomas
    • Travis W.D. Update on small cell carcinoma and its differentiation from squamous cell carcinoma and other non-small cell carcinomas. Mod Pathol 2012, 25(Suppl 1):S18-S30.
    • (2012) Mod Pathol , vol.25 , Issue.SUPPL 1
    • Travis, W.D.1
  • 73
    • 40149100486 scopus 로고    scopus 로고
    • Application of immunohistochemistry to the diagnosis of primary and metastatic carcinoma of the lung
    • Jagirdar J. Application of immunohistochemistry to the diagnosis of primary and metastatic carcinoma of the lung. Arch Pathol Lab Med 2008, 132:384-396.
    • (2008) Arch Pathol Lab Med , vol.132 , pp. 384-396
    • Jagirdar, J.1
  • 74
    • 79954626149 scopus 로고    scopus 로고
    • Pathologic diagnosis and classification of lung cancer in small biopsies and cytology: strategic management of tissue for molecular testing
    • Travis W.D., Rekhtman N. Pathologic diagnosis and classification of lung cancer in small biopsies and cytology: strategic management of tissue for molecular testing. Semin Respir Crit Care Med 2011, 32(1):22-31.
    • (2011) Semin Respir Crit Care Med , vol.32 , Issue.1 , pp. 22-31
    • Travis, W.D.1    Rekhtman, N.2
  • 75
    • 80455123686 scopus 로고    scopus 로고
    • Pathology of lung cancer
    • Travis W.D. Pathology of lung cancer. Clin Chest Med 2011, 32(4):669-692.
    • (2011) Clin Chest Med , vol.32 , Issue.4 , pp. 669-692
    • Travis, W.D.1
  • 76
    • 75649098689 scopus 로고    scopus 로고
    • Histology matters: individualizing treatment in non-small cell lung cancer
    • Neal J.W. Histology matters: individualizing treatment in non-small cell lung cancer. Oncologist 2010, 15(1):3-5.
    • (2010) Oncologist , vol.15 , Issue.1 , pp. 3-5
    • Neal, J.W.1
  • 77
    • 77649174473 scopus 로고    scopus 로고
    • Comparison of thyroid transcription factor-1 expression by 2 monoclonal antibodies in pulmonary and nonpulmonary primary tumors
    • Matoso A., Singh K., Jacob R., et al. Comparison of thyroid transcription factor-1 expression by 2 monoclonal antibodies in pulmonary and nonpulmonary primary tumors. Appl Immunohistochem Mol Morphol 2010, 18(2):142-149.
    • (2010) Appl Immunohistochem Mol Morphol , vol.18 , Issue.2 , pp. 142-149
    • Matoso, A.1    Singh, K.2    Jacob, R.3
  • 78
    • 80051785282 scopus 로고    scopus 로고
    • Significance of thymidylate synthase and thyroid transcription factor 1 expression in patients with nonsquamous non-small cell lung cancer treated with pemetrexed-based chemotherapy
    • Sun J.M., Han J., Ahn S., Park K., Ahn M.J. Significance of thymidylate synthase and thyroid transcription factor 1 expression in patients with nonsquamous non-small cell lung cancer treated with pemetrexed-based chemotherapy. J Thorac Oncol 2011, 6(8):1392-1399.
    • (2011) J Thorac Oncol , vol.6 , Issue.8 , pp. 1392-1399
    • Sun, J.M.1    Han, J.2    Ahn, S.3    Park, K.4    Ahn, M.J.5
  • 79
    • 58149149814 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in small cell lung cancer
    • Tatematsu A., Shimizu J., Murakami Y., et al. Epidermal growth factor receptor mutations in small cell lung cancer. Clin Cancer Res 2008, 14(19):6092-6096.
    • (2008) Clin Cancer Res , vol.14 , Issue.19 , pp. 6092-6096
    • Tatematsu, A.1    Shimizu, J.2    Murakami, Y.3
  • 80
    • 34748863599 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung
    • Fukui T., Tsuta K., Furuta K., et al. Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung. Cancer Sci 2007, 98(11):1714-1719.
    • (2007) Cancer Sci , vol.98 , Issue.11 , pp. 1714-1719
    • Fukui, T.1    Tsuta, K.2    Furuta, K.3
  • 81
    • 33745913034 scopus 로고    scopus 로고
    • EGFR mutations in small-cell lung cancers in patients who have never smoked
    • Zakowski M.F., Ladanyi M., Kris M.G. EGFR mutations in small-cell lung cancers in patients who have never smoked. N Engl J Med 2006, 355(2):213-215.
    • (2006) N Engl J Med , vol.355 , Issue.2 , pp. 213-215
    • Zakowski, M.F.1    Ladanyi, M.2    Kris, M.G.3
  • 82
    • 78649855894 scopus 로고    scopus 로고
    • Identification of EGFR mutations in lung sarcomatoid carcinoma
    • Leone A., Graziano P., Gasbarra R., et al. Identification of EGFR mutations in lung sarcomatoid carcinoma. Int J Cancer 2011, 128(3):732-735.
    • (2011) Int J Cancer , vol.128 , Issue.3 , pp. 732-735
    • Leone, A.1    Graziano, P.2    Gasbarra, R.3
  • 83
    • 79954741752 scopus 로고    scopus 로고
    • Efficacy of gefitinib for non-adenocarcinoma non-small-cell lung cancer patients harbouring epidermal growth factor receptor mutations: a pooled analysis of published reports
    • Shukuya T., Takahashi T., Kaira R., et al. Efficacy of gefitinib for non-adenocarcinoma non-small-cell lung cancer patients harbouring epidermal growth factor receptor mutations: a pooled analysis of published reports. Cancer Sci 2011, 102(5):1032-1037.
    • (2011) Cancer Sci , vol.102 , Issue.5 , pp. 1032-1037
    • Shukuya, T.1    Takahashi, T.2    Kaira, R.3
  • 85
    • 22044453790 scopus 로고    scopus 로고
    • Erlotinib in lung cancer: molecular and clinical predictors of outcome
    • Tsao M.S., Sakurada A., Cutz J.C., et al. Erlotinib in lung cancer: molecular and clinical predictors of outcome. N Engl J Med 2005, 353(2):133-144.
    • (2005) N Engl J Med , vol.353 , Issue.2 , pp. 133-144
    • Tsao, M.S.1    Sakurada, A.2    Cutz, J.C.3
  • 86
    • 65349166324 scopus 로고    scopus 로고
    • Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma
    • Lebanony D., Benjamin H., Gilad S., et al. Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma. J Clin Oncol 2009, 27(12):2030-2037.
    • (2009) J Clin Oncol , vol.27 , Issue.12 , pp. 2030-2037
    • Lebanony, D.1    Benjamin, H.2    Gilad, S.3
  • 87
    • 74549118209 scopus 로고    scopus 로고
    • Accurate classification of non-small cell lung carcinoma using a novel microRNA-based approach
    • Bishop J.A., Benjamin H., Cholakh H., et al. Accurate classification of non-small cell lung carcinoma using a novel microRNA-based approach. Clin Cancer Res 2010, 16(2):610-619.
    • (2010) Clin Cancer Res , vol.16 , Issue.2 , pp. 610-619
    • Bishop, J.A.1    Benjamin, H.2    Cholakh, H.3
  • 88
    • 79251579006 scopus 로고    scopus 로고
    • MiR-205 expression levels in nonsmall cell lung cancer do not always distinguish adenocarcinomas from squamous cell carcinomas
    • Del Vescovo V., Cantaloni C., Cucino A., et al. miR-205 expression levels in nonsmall cell lung cancer do not always distinguish adenocarcinomas from squamous cell carcinomas. Am J Surg Pathol 2011, 35(2):268-275.
    • (2011) Am J Surg Pathol , vol.35 , Issue.2 , pp. 268-275
    • Del Vescovo, V.1    Cantaloni, C.2    Cucino, A.3
  • 89
    • 80355129921 scopus 로고    scopus 로고
    • Heterogeneity of large cell carcinoma of the lung. An immunophenotypic and miRNA-based analysis
    • Barbareschi M., Cantaloni C., Del Vescovo V., et al. Heterogeneity of large cell carcinoma of the lung. An immunophenotypic and miRNA-based analysis. Am J Clin Pathol 2011, 136(5):773-782.
    • (2011) Am J Clin Pathol , vol.136 , Issue.5 , pp. 773-782
    • Barbareschi, M.1    Cantaloni, C.2    Del Vescovo, V.3
  • 90
    • 84863781238 scopus 로고    scopus 로고
    • Use of mutation specific antibodies to detect EGFR status in small biopsy and cytology specimens of lung adenocarcinoma
    • Hasanovic A., Ang D., Moreira A.L., Zakowski M.F. Use of mutation specific antibodies to detect EGFR status in small biopsy and cytology specimens of lung adenocarcinoma. Lung Cancer 2012, 77(2):299-305.
    • (2012) Lung Cancer , vol.77 , Issue.2 , pp. 299-305
    • Hasanovic, A.1    Ang, D.2    Moreira, A.L.3    Zakowski, M.F.4
  • 91
    • 84861338508 scopus 로고    scopus 로고
    • Effusion immunohistochemistry as an alternative approach for the selection of first-line targeted therapy in advanced lung adenocarcinoma
    • Tsai T.H., Wu S.G., Chang Y.L., et al. Effusion immunohistochemistry as an alternative approach for the selection of first-line targeted therapy in advanced lung adenocarcinoma. J Thorac Oncol 2012, 7(6):993-1000.
    • (2012) J Thorac Oncol , vol.7 , Issue.6 , pp. 993-1000
    • Tsai, T.H.1    Wu, S.G.2    Chang, Y.L.3
  • 92
    • 84862854126 scopus 로고    scopus 로고
    • EGFR mutation-specific antibodies in pulmonary adenocarcinoma: a comparison with DNA direct sequencing
    • Ambrosini-Spaltro A., Campanini N., Bortesi B., et al. EGFR mutation-specific antibodies in pulmonary adenocarcinoma: a comparison with DNA direct sequencing. Appl Immunohistochem Mol Morphol 2012, 20(4):356-362.
    • (2012) Appl Immunohistochem Mol Morphol , vol.20 , Issue.4 , pp. 356-362
    • Ambrosini-Spaltro, A.1    Campanini, N.2    Bortesi, B.3
  • 93
    • 65649128973 scopus 로고    scopus 로고
    • Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer
    • Yu J., Kane S., Wu J., et al. Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer. Clin Cancer Res 2009, 15(9):3023-3028.
    • (2009) Clin Cancer Res , vol.15 , Issue.9 , pp. 3023-3028
    • Yu, J.1    Kane, S.2    Wu, J.3
  • 94
    • 77649140830 scopus 로고    scopus 로고
    • Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR
    • Brevet M., Arcila M., Ladanyi M. Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR. J Mol Diagn 2010, 12(2):169-176.
    • (2010) J Mol Diagn , vol.12 , Issue.2 , pp. 169-176
    • Brevet, M.1    Arcila, M.2    Ladanyi, M.3
  • 95
    • 77957956767 scopus 로고    scopus 로고
    • Usefulness of tissue microarrays for assessment of protein expression, gene copy number and mutational status of EGFR in lung adenocarcinoma
    • Ilie M.I., Hofman V., Bonnetaud C., et al. Usefulness of tissue microarrays for assessment of protein expression, gene copy number and mutational status of EGFR in lung adenocarcinoma. Virchows Arch 2010, 457(4):483-495.
    • (2010) Virchows Arch , vol.457 , Issue.4 , pp. 483-495
    • Ilie, M.I.1    Hofman, V.2    Bonnetaud, C.3
  • 96
    • 77958198161 scopus 로고    scopus 로고
    • Novel epidermal growth factor receptor mutation-specific antibodies for non-small cell lung cancer: immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations
    • Kato Y., Peled N., Wynes M.W., et al. Novel epidermal growth factor receptor mutation-specific antibodies for non-small cell lung cancer: immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations. J Thorac Oncol 2010, 5(10):1551-1558.
    • (2010) J Thorac Oncol , vol.5 , Issue.10 , pp. 1551-1558
    • Kato, Y.1    Peled, N.2    Wynes, M.W.3
  • 97
    • 80052588962 scopus 로고    scopus 로고
    • Identification of non-small-cell lung cancer with activating EGFR mutations in malignant effusion and cerebrospinal fluid: rapid and sensitive detection of exon 19 deletion E746-A750 and exon 21 L858R mutation by immunocytochemistry
    • Kawahara A., Azuma K., Sumi A., et al. Identification of non-small-cell lung cancer with activating EGFR mutations in malignant effusion and cerebrospinal fluid: rapid and sensitive detection of exon 19 deletion E746-A750 and exon 21 L858R mutation by immunocytochemistry. Lung Cancer 2011, 74(1):35-40.
    • (2011) Lung Cancer , vol.74 , Issue.1 , pp. 35-40
    • Kawahara, A.1    Azuma, K.2    Sumi, A.3
  • 98
    • 77953720122 scopus 로고    scopus 로고
    • Molecular diagnosis of activating EGFR mutations in non-small cell lung cancer using mutation-specific antibodies for immunohistochemical analysis
    • Kawahara A., Yamamoto C., Nakashima K., et al. Molecular diagnosis of activating EGFR mutations in non-small cell lung cancer using mutation-specific antibodies for immunohistochemical analysis. Clin Cancer Res 2010, 16(12):3163-3170.
    • (2010) Clin Cancer Res , vol.16 , Issue.12 , pp. 3163-3170
    • Kawahara, A.1    Yamamoto, C.2    Nakashima, K.3
  • 99
    • 77954224784 scopus 로고    scopus 로고
    • Immunohistochemical detection of EGFR mutation using mutation-specific antibodies in lung cancer
    • Kitamura A., Hosoda W., Sasaki E., Mitsudomi T., Yatabe Y. Immunohistochemical detection of EGFR mutation using mutation-specific antibodies in lung cancer. Clin Cancer Res 2010, 16(13):3349-3355.
    • (2010) Clin Cancer Res , vol.16 , Issue.13 , pp. 3349-3355
    • Kitamura, A.1    Hosoda, W.2    Sasaki, E.3    Mitsudomi, T.4    Yatabe, Y.5
  • 100
    • 79957676308 scopus 로고    scopus 로고
    • The usefulness of mutation-specific antibodies in detecting epidermal growth factor receptor mutations and in predicting response to tyrosine kinase inhibitor therapy in lung adenocarcinoma
    • Kozu Y., Tsuta K., Kohno T., et al. The usefulness of mutation-specific antibodies in detecting epidermal growth factor receptor mutations and in predicting response to tyrosine kinase inhibitor therapy in lung adenocarcinoma. Lung Cancer 2011, 73(1):45-50.
    • (2011) Lung Cancer , vol.73 , Issue.1 , pp. 45-50
    • Kozu, Y.1    Tsuta, K.2    Kohno, T.3
  • 101
    • 78751560428 scopus 로고    scopus 로고
    • Immunohistochemical detection of mutated epidermal growth factor receptors in pulmonary adenocarcinoma
    • Nakamura H., Mochizuki A., Shinmyo T., et al. Immunohistochemical detection of mutated epidermal growth factor receptors in pulmonary adenocarcinoma. Anticancer Res 2010, 30(12):5233-5237.
    • (2010) Anticancer Res , vol.30 , Issue.12 , pp. 5233-5237
    • Nakamura, H.1    Mochizuki, A.2    Shinmyo, T.3
  • 102
    • 78650928556 scopus 로고    scopus 로고
    • Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer
    • Dec
    • Simonetti S., Molina M.A., Queralt C., et al. Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer. J Transl Med 2010, 8(Dec 18):135.
    • (2010) J Transl Med , vol.8 , Issue.18 , pp. 135
    • Simonetti, S.1    Molina, M.A.2    Queralt, C.3
  • 103
    • 79961212400 scopus 로고    scopus 로고
    • Including total EGFR staining in scoring improves EGFR mutations detected by mutation-specific antibodies and EGFR TKIs response prediction
    • Wu S.G., Chang Y.L., Lin J.W., et al. Including total EGFR staining in scoring improves EGFR mutations detected by mutation-specific antibodies and EGFR TKIs response prediction. PLoS One 2011, 6(8):e23303.
    • (2011) PLoS One , vol.6 , Issue.8
    • Wu, S.G.1    Chang, Y.L.2    Lin, J.W.3
  • 104
    • 84858005348 scopus 로고    scopus 로고
    • The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group
    • Thunnissen E., Kerr K.M., Herth F.J.F., et al. The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group. Lung Cancer 2012, 76(1):1-18.
    • (2012) Lung Cancer , vol.76 , Issue.1 , pp. 1-18
    • Thunnissen, E.1    Kerr, K.M.2    Herth, F.J.F.3
  • 105
    • 84655163448 scopus 로고    scopus 로고
    • Association of the expression of mutant epidermal growth factor receptor protein as determined with mutation-specific antibodies in non-small cell lung cancer with progression-free survival after gefitinib treatment
    • Azuma K., Okamoto I., Kawahara A., et al. Association of the expression of mutant epidermal growth factor receptor protein as determined with mutation-specific antibodies in non-small cell lung cancer with progression-free survival after gefitinib treatment. J Thorac Oncol 2012, 7(1):122-127.
    • (2012) J Thorac Oncol , vol.7 , Issue.1 , pp. 122-127
    • Azuma, K.1    Okamoto, I.2    Kawahara, A.3
  • 106
    • 84860709024 scopus 로고    scopus 로고
    • Guidelines for biomarker testing in advanced non-small-cell lung cancer. A National Consensus of the Spanish Society of Medical Oncology (SEOM) and the Spanish Society of Pathology (SEAP)
    • Garrido P., de Castro J., Concha A., et al. Guidelines for biomarker testing in advanced non-small-cell lung cancer. A National Consensus of the Spanish Society of Medical Oncology (SEOM) and the Spanish Society of Pathology (SEAP). Clin Transl Oncol 2012, 14(5):338-349.
    • (2012) Clin Transl Oncol , vol.14 , Issue.5 , pp. 338-349
    • Garrido, P.1    de Castro, J.2    Concha, A.3
  • 107
    • 79951774364 scopus 로고    scopus 로고
    • Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH
    • Yi E.S., Boland J.M., Maleszewski J.J., et al. Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH. J Thorac Oncol 2011, 6(3):459-465.
    • (2011) J Thorac Oncol , vol.6 , Issue.3 , pp. 459-465
    • Yi, E.S.1    Boland, J.M.2    Maleszewski, J.J.3
  • 108
    • 84655170204 scopus 로고    scopus 로고
    • Worse disease-free survival in never-smokers with ALK+ lung adenocarcinoma
    • Yang P., Kulig K., Boland J.M., et al. Worse disease-free survival in never-smokers with ALK+ lung adenocarcinoma. J Thorac Oncol 2012, 7(1):90-97.
    • (2012) J Thorac Oncol , vol.7 , Issue.1 , pp. 90-97
    • Yang, P.1    Kulig, K.2    Boland, J.M.3
  • 109
    • 79951769488 scopus 로고    scopus 로고
    • Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: correlation with fluorescence in situ hybridization
    • Paik J.H., Choe G., Kim H., Choe J.Y., et al. Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: correlation with fluorescence in situ hybridization. J Thorac Oncol 2011, 6(8):466-472.
    • (2011) J Thorac Oncol , vol.6 , Issue.8 , pp. 466-472
    • Paik, J.H.1    Choe, G.2    Kim, H.3    Choe, J.Y.4
  • 110
    • 84857781304 scopus 로고    scopus 로고
    • Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: a French study
    • McLeer-Florin A., Moro-Sibilot D., Melis A., et al. Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: a French study. J Thorac Oncol 2012, 7(2):348-354.
    • (2012) J Thorac Oncol , vol.7 , Issue.2 , pp. 348-354
    • McLeer-Florin, A.1    Moro-Sibilot, D.2    Melis, A.3
  • 111
    • 79956318148 scopus 로고    scopus 로고
    • Reflex testing for epidermal growth factor receptor mutation and anaplastic lymphoma kinase fluorescence in situ hybridization in non-small cell lung cancer
    • Mino-Kenudson M., Mark E.J. Reflex testing for epidermal growth factor receptor mutation and anaplastic lymphoma kinase fluorescence in situ hybridization in non-small cell lung cancer. Arch Pathol Lab Med 2011, 135(5):655-664.
    • (2011) Arch Pathol Lab Med , vol.135 , Issue.5 , pp. 655-664
    • Mino-Kenudson, M.1    Mark, E.J.2
  • 112
    • 84870891665 scopus 로고    scopus 로고
    • A screening method for the ALK fusion gene in NSCLC
    • Mar
    • Murakami Y., Mitsudomi T., Yatabe Y. A screening method for the ALK fusion gene in NSCLC. Front Oncol 2012, 2(Mar 16):1-9.
    • (2012) Front Oncol , vol.2 , Issue.16 , pp. 1-9
    • Murakami, Y.1    Mitsudomi, T.2    Yatabe, Y.3
  • 113
    • 84862109270 scopus 로고    scopus 로고
    • Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma
    • Koperek O., Kornauth C., Capper D., et al. Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma. Am J Surg Pathol 2012, 36(6):844-850.
    • (2012) Am J Surg Pathol , vol.36 , Issue.6 , pp. 844-850
    • Koperek, O.1    Kornauth, C.2    Capper, D.3
  • 114
    • 84865089246 scopus 로고    scopus 로고
    • Analysis of receptor tyrosine kinase ROS1 positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion
    • Rimkunas V.M., Crosby K.E., Kelly M.E., et al. Analysis of receptor tyrosine kinase ROS1 positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion. Clin Cancer Res 2012, 18(16):444-457.
    • (2012) Clin Cancer Res , vol.18 , Issue.16 , pp. 444-457
    • Rimkunas, V.M.1    Crosby, K.E.2    Kelly, M.E.3
  • 115
    • 74949118636 scopus 로고    scopus 로고
    • Use of epidermal growth factor receptor/Kirsten rat sarcoma 2 viral oncogene homolog mutation testing to define clonal lung relationship among multiple lung adenocarcinomas. Comparison with clinical guidelines
    • Girard N., Deshpande C., Azzoli C.G., et al. Use of epidermal growth factor receptor/Kirsten rat sarcoma 2 viral oncogene homolog mutation testing to define clonal lung relationship among multiple lung adenocarcinomas. Comparison with clinical guidelines. Chest 2010, 137(1):46-52.
    • (2010) Chest , vol.137 , Issue.1 , pp. 46-52
    • Girard, N.1    Deshpande, C.2    Azzoli, C.G.3
  • 116
    • 84871920961 scopus 로고    scopus 로고
    • Consistent mutation status within histologically heterogeneous lung cancer lesions
    • Mattsson J.S., Imgenberg-Kreuz J., Edlund K., Botling J., Micke P. Consistent mutation status within histologically heterogeneous lung cancer lesions. Histopathology 2012, 61(4):744-748.
    • (2012) Histopathology , vol.61 , Issue.4 , pp. 744-748
    • Mattsson, J.S.1    Imgenberg-Kreuz, J.2    Edlund, K.3    Botling, J.4    Micke, P.5
  • 117
    • 61449259809 scopus 로고    scopus 로고
    • Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas
    • Varella-Garcia M., Xavier A.C., et al. Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas. Cancer Prev Res 2008, 13(3):192-200.
    • (2008) Cancer Prev Res , vol.13 , Issue.3 , pp. 192-200
    • Varella-Garcia, M.1    Xavier, A.C.2
  • 118
    • 43649099401 scopus 로고    scopus 로고
    • Intratumour heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib
    • Taniguchi K., Okami J., Kodama K., Higashiyama M., Kato K. Intratumour heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib. Cancer Sci 2008, 95(5):929-935.
    • (2008) Cancer Sci , vol.95 , Issue.5 , pp. 929-935
    • Taniguchi, K.1    Okami, J.2    Kodama, K.3    Higashiyama, M.4    Kato, K.5
  • 119
    • 80051612067 scopus 로고    scopus 로고
    • Heterogeneous distribution of EGFR mutations is extremely rare in lung adenocarcinoma
    • Yatabe Y., Matsuo K., Mitsudomi T. Heterogeneous distribution of EGFR mutations is extremely rare in lung adenocarcinoma. J Clin Oncol 2011, 29(22):2972-2977.
    • (2011) J Clin Oncol , vol.29 , Issue.22 , pp. 2972-2977
    • Yatabe, Y.1    Matsuo, K.2    Mitsudomi, T.3
  • 120
    • 70149110218 scopus 로고    scopus 로고
    • Clinical implications of KRAS mutations in lung cancer patients treated with tyrosine kinase inhibitors: an important role for mutations in minor clones
    • Marchetti A., Milella A., Felicioni L., et al. Clinical implications of KRAS mutations in lung cancer patients treated with tyrosine kinase inhibitors: an important role for mutations in minor clones. Neoplasia 2009, 11(10):1084-1092.
    • (2009) Neoplasia , vol.11 , Issue.10 , pp. 1084-1092
    • Marchetti, A.1    Milella, A.2    Felicioni, L.3
  • 121
    • 78650499456 scopus 로고    scopus 로고
    • Good response to gefitinib in lung adenocarcinoma harboring coexisting EML4-ALK fusion gene and EGFR mutation
    • Kuo Y.W., Wu S.G., Ho C.C., Shih J.Y. Good response to gefitinib in lung adenocarcinoma harboring coexisting EML4-ALK fusion gene and EGFR mutation. J Thorac Oncol 2010, 5(12):2039.
    • (2010) J Thorac Oncol , vol.5 , Issue.12 , pp. 2039
    • Kuo, Y.W.1    Wu, S.G.2    Ho, C.C.3    Shih, J.Y.4
  • 122
    • 78650950138 scopus 로고    scopus 로고
    • EGFR and EML4-ALK gene mutations in NSCLC: a case report of erlotinib-resistant patient with both concomitant mutations
    • Tiseo M., Gelsomino F., Boggiani D., et al. EGFR and EML4-ALK gene mutations in NSCLC: a case report of erlotinib-resistant patient with both concomitant mutations. Lung Cancer 2011, 71(2):241-243.
    • (2011) Lung Cancer , vol.71 , Issue.2 , pp. 241-243
    • Tiseo, M.1    Gelsomino, F.2    Boggiani, D.3
  • 123
    • 80054911665 scopus 로고    scopus 로고
    • Lung adenocarcinoma with concurrent exon 19 EGFR mutation and ALK rearrangement responding to erlotinib
    • Popat S., Vieira de Araújo A., Min T., et al. Lung adenocarcinoma with concurrent exon 19 EGFR mutation and ALK rearrangement responding to erlotinib. J Thorac Oncol 2011, 6(11):1962.
    • (2011) J Thorac Oncol , vol.6 , Issue.11 , pp. 1962
    • Popat, S.1    Vieira de Araújo, A.2    Min, T.3
  • 124
    • 84863776935 scopus 로고    scopus 로고
    • Differential sensitivities to tyrosine kinase inhibitors in NSCLC harbouring EGFR mutation and ALK translocation
    • Lee J.K., Kim T.M., Koh Y., et al. Differential sensitivities to tyrosine kinase inhibitors in NSCLC harbouring EGFR mutation and ALK translocation. Lung Cancer 2012, 77(2):460-463.
    • (2012) Lung Cancer , vol.77 , Issue.2 , pp. 460-463
    • Lee, J.K.1    Kim, T.M.2    Koh, Y.3
  • 125
    • 77954566882 scopus 로고    scopus 로고
    • Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine
    • Dias-Santagata Akhavanfard S., David S.D., et al. Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine. EMBO Mol Med 2010, 2(5):146-158.
    • (2010) EMBO Mol Med , vol.2 , Issue.5 , pp. 146-158
    • Dias-Santagata, A.S.1    David, S.D.2
  • 126
    • 82355191818 scopus 로고    scopus 로고
    • Implementing multiplex genotyping of non-small-cell lung cancers into routine clinical practice
    • Sequist L.V., Heist R.S., Shaw A.T., et al. Implementing multiplex genotyping of non-small-cell lung cancers into routine clinical practice. Ann Oncol 2011, 22(12):2616-2624.
    • (2011) Ann Oncol , vol.22 , Issue.12 , pp. 2616-2624
    • Sequist, L.V.1    Heist, R.S.2    Shaw, A.T.3
  • 127
    • 44249086425 scopus 로고    scopus 로고
    • Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship
    • Molina J.R., Yang P., Cassivi S.D., Schild S.E., Adjei A.A. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 2008, 83(5):584-594.
    • (2008) Mayo Clin Proc , vol.83 , Issue.5 , pp. 584-594
    • Molina, J.R.1    Yang, P.2    Cassivi, S.D.3    Schild, S.E.4    Adjei, A.A.5
  • 128
    • 0033934570 scopus 로고    scopus 로고
    • Preoperative histological classification of primary lung cancer: accuracy of diagnosis and use of the non-small cell category
    • Edwards S.L., Roberts C., McKean M.E., Cockburn J.S., Jeffrey R.R., Kerr K.M. Preoperative histological classification of primary lung cancer: accuracy of diagnosis and use of the non-small cell category. J Clin Pathol 2000, 53(7):537-540.
    • (2000) J Clin Pathol , vol.53 , Issue.7 , pp. 537-540
    • Edwards, S.L.1    Roberts, C.2    McKean, M.E.3    Cockburn, J.S.4    Jeffrey, R.R.5    Kerr, K.M.6
  • 130
    • 70350120598 scopus 로고    scopus 로고
    • Histologic considerations for individualized systemic therapy approaches for the management of non-small cell lung cancer
    • West H., Harpole D., Travis W. Histologic considerations for individualized systemic therapy approaches for the management of non-small cell lung cancer. Chest 2009, 136(4):1112-1118.
    • (2009) Chest , vol.136 , Issue.4 , pp. 1112-1118
    • West, H.1    Harpole, D.2    Travis, W.3
  • 131
    • 70350446998 scopus 로고    scopus 로고
    • Morphology and a limited number of immunohistochemical markers may efficiently subtype non-small-cell lung cancer
    • Rossi G., Papotti M., Barbareschi M., Graziano P., Pelosi G. Morphology and a limited number of immunohistochemical markers may efficiently subtype non-small-cell lung cancer. J Clin Oncol 2009, 27(28):e141-e142.
    • (2009) J Clin Oncol , vol.27 , Issue.28
    • Rossi, G.1    Papotti, M.2    Barbareschi, M.3    Graziano, P.4    Pelosi, G.5
  • 132
    • 79951767771 scopus 로고    scopus 로고
    • Accuracy of fine needle aspiration cytology in the pathological typing of non-small cell lung cancer
    • Nizzoli R., Tiseo M., Gelsomino F., et al. Accuracy of fine needle aspiration cytology in the pathological typing of non-small cell lung cancer. J Thorac Oncol 2011, 6(3):489-493.
    • (2011) J Thorac Oncol , vol.6 , Issue.3 , pp. 489-493
    • Nizzoli, R.1    Tiseo, M.2    Gelsomino, F.3
  • 133
    • 0034425251 scopus 로고    scopus 로고
    • Cell block cytology. Improved preparation and its efficacy in diagnostic cytology
    • Nathan N.A., Narayan E., Smith M.M., Horn M.J. Cell block cytology. Improved preparation and its efficacy in diagnostic cytology. Am J Clin Pathol 2000, 114(4):599-606.
    • (2000) Am J Clin Pathol , vol.114 , Issue.4 , pp. 599-606
    • Nathan, N.A.1    Narayan, E.2    Smith, M.M.3    Horn, M.J.4
  • 134
    • 79951769998 scopus 로고    scopus 로고
    • Suitability of thoracic cytology for new therapeutic paradigms in non-small cell lung carcinoma: high accuracy of tumor subtyping and feasibility of EGFR and KRAS molecular testing
    • Rekhtman N., Brandt S.M., Sigel C.S., et al. Suitability of thoracic cytology for new therapeutic paradigms in non-small cell lung carcinoma: high accuracy of tumor subtyping and feasibility of EGFR and KRAS molecular testing. J Thorac Oncol 2011, 6(4):451-458.
    • (2011) J Thorac Oncol , vol.6 , Issue.4 , pp. 451-458
    • Rekhtman, N.1    Brandt, S.M.2    Sigel, C.S.3
  • 135
    • 84859429097 scopus 로고    scopus 로고
    • EGFR and KRAS mutation analysis in cytologic samples of lung adenocarcinoma enabled by laser capture microdissection
    • Chowdhuri S.R., Xi L., Pham T.H., et al. EGFR and KRAS mutation analysis in cytologic samples of lung adenocarcinoma enabled by laser capture microdissection. Mod Pathol 2012, 25(4):548-555.
    • (2012) Mod Pathol , vol.25 , Issue.4 , pp. 548-555
    • Chowdhuri, S.R.1    Xi, L.2    Pham, T.H.3
  • 136
    • 80053386829 scopus 로고    scopus 로고
    • Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis
    • Shaw A.T., Yeap B.Y., Solomon B.J., et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol 2011, 12(11):1004-1012.
    • (2011) Lancet Oncol , vol.12 , Issue.11 , pp. 1004-1012
    • Shaw, A.T.1    Yeap, B.Y.2    Solomon, B.J.3
  • 137
    • 84861594994 scopus 로고    scopus 로고
    • Oncogenic pathways, molecularly targeted therapies, and highlighted clinical trials in non-small-cell lung cancer (NSCLC)
    • Reungwetwattana T., Weroha S.J., Molina J.R. Oncogenic pathways, molecularly targeted therapies, and highlighted clinical trials in non-small-cell lung cancer (NSCLC). Clin Lung Cancer 2012, 13(4):252-266.
    • (2012) Clin Lung Cancer , vol.13 , Issue.4 , pp. 252-266
    • Reungwetwattana, T.1    Weroha, S.J.2    Molina, J.R.3
  • 138
    • 79955692762 scopus 로고    scopus 로고
    • Mechanisms of resistance to epidermal growth factor receptor tyrosine kinase inhibitors in patients with advanced non-small-cell lung cancer: clinical and molecular considerations
    • Pallis A., Briasoulis E., Linardou H., et al. Mechanisms of resistance to epidermal growth factor receptor tyrosine kinase inhibitors in patients with advanced non-small-cell lung cancer: clinical and molecular considerations. Curr Med Chem 2011, 18(11):1613-1628.
    • (2011) Curr Med Chem , vol.18 , Issue.11 , pp. 1613-1628
    • Pallis, A.1    Briasoulis, E.2    Linardou, H.3
  • 139
    • 38049150665 scopus 로고    scopus 로고
    • MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
    • Bean J., Brennan C., Shih J.Y., et al. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci 2007, 104(52):20932-20937.
    • (2007) Proc Natl Acad Sci , vol.104 , Issue.52 , pp. 20932-20937
    • Bean, J.1    Brennan, C.2    Shih, J.Y.3
  • 140
    • 80052793410 scopus 로고    scopus 로고
    • A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors
    • Sasaki T., Koivunen J., Ogino A., et al. A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors. Cancer Res 2011, 71(18):6051-6060.
    • (2011) Cancer Res , vol.71 , Issue.18 , pp. 6051-6060
    • Sasaki, T.1    Koivunen, J.2    Ogino, A.3
  • 141
    • 77957316871 scopus 로고    scopus 로고
    • A comparison of ARMS and DNA sequencing for mutation analysis in clinical biopsy samples
    • Ellison G., Donald E., McWalter G., et al. A comparison of ARMS and DNA sequencing for mutation analysis in clinical biopsy samples. J Exp Clin Cancer Res 2010, 6(29):132.
    • (2010) J Exp Clin Cancer Res , vol.6 , Issue.29 , pp. 132
    • Ellison, G.1    Donald, E.2    McWalter, G.3
  • 142
    • 14644418434 scopus 로고    scopus 로고
    • Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner
    • Akbari M., Hansen M.D., Halgunset J., Skorpen F., Krokan H.E. Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner. J Mol Diagn 2005, 7(1):36-39.
    • (2005) J Mol Diagn , vol.7 , Issue.1 , pp. 36-39
    • Akbari, M.1    Hansen, M.D.2    Halgunset, J.3    Skorpen, F.4    Krokan, H.E.5
  • 143
    • 0032755991 scopus 로고    scopus 로고
    • A high frequency of sequence alterations is due to formalin fixation of archival specimens
    • Williams C., Pontén F., Moberg C., et al. A high frequency of sequence alterations is due to formalin fixation of archival specimens. Am J Pathol 1999, 155(2):1467-1471.
    • (1999) Am J Pathol , vol.155 , Issue.2 , pp. 1467-1471
    • Williams, C.1    Pontén, F.2    Moberg, C.3


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