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Volumn 72, Issue 3, 2011, Pages 309-315

Frequent ALK rearrangement and TTF-1/p63 co-expression in lung adenocarcinoma with signet-ring cell component

Author keywords

Adenocarcinoma; ALK translocation; Fluorescence in situ hybridization; Immunohistochemistry; Polymerase chain reaction; Signet ring cell

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN P63; THYROID TRANSCRIPTION FACTOR 1;

EID: 79955467025     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2010.09.013     Document Type: Article
Times cited : (107)

References (37)
  • 2
    • 70349342712 scopus 로고    scopus 로고
    • EML4-ALK: honing in on a new target in non-small-cell lung cancer
    • Horn L., Pao W. EML4-ALK: honing in on a new target in non-small-cell lung cancer. J Clin Oncol 2009, 27:4232-4235.
    • (2009) J Clin Oncol , vol.27 , pp. 4232-4235
    • Horn, L.1    Pao, W.2
  • 3
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004, 350:2129-2139.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5    Brannigan, B.W.6
  • 4
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
    • Paez J.G., Janne P.A., Lee J.C., Tracy S., Greulich H., Gabriel S., et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004, 304:1497-1500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3    Tracy, S.4    Greulich, H.5    Gabriel, S.6
  • 5
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • Soda M., Choi Y.L., Enomoto M., Takada S., Yamashita Y., Ishikawa S., et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007, 448:561-566.
    • (2007) Nature , vol.448 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3    Takada, S.4    Yamashita, Y.5    Ishikawa, S.6
  • 6
    • 67650441507 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas
    • Boland J.M., Erdogan S., Vasmatzis G., Yang P., Tillmans L.S., Erickson Johnson M.R., et al. Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas. Hum Pathol 2009, 40:1152-1158.
    • (2009) Hum Pathol , vol.40 , pp. 1152-1158
    • Boland, J.M.1    Erdogan, S.2    Vasmatzis, G.3    Yang, P.4    Tillmans, L.S.5    Erickson Johnson, M.R.6
  • 7
    • 48549098388 scopus 로고    scopus 로고
    • Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
    • Choi Y.L., Takeuchi K., Soda M., Inamura K., Togashi Y., Hatano S., et al. Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer. Cancer Res 2008, 68:4971-4976.
    • (2008) Cancer Res , vol.68 , pp. 4971-4976
    • Choi, Y.L.1    Takeuchi, K.2    Soda, M.3    Inamura, K.4    Togashi, Y.5    Hatano, S.6
  • 8
    • 63949087355 scopus 로고    scopus 로고
    • EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset
    • Inamura K., Takeuchi K., Togashi Y., Hatano S., Ninomiya H., Motoi N., et al. EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol 2009, 22:508-515.
    • (2009) Mod Pathol , vol.22 , pp. 508-515
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3    Hatano, S.4    Ninomiya, H.5    Motoi, N.6
  • 9
    • 37549060017 scopus 로고    scopus 로고
    • EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
    • Inamura K., Takeuchi K., Togashi Y., Nomura K., Ninomiya H., Okui M., et al. EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 2008, 3:13-17.
    • (2008) J Thorac Oncol , vol.3 , pp. 13-17
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3    Nomura, K.4    Ninomiya, H.5    Okui, M.6
  • 11
    • 69349083935 scopus 로고    scopus 로고
    • Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
    • Rodig S.J., Mino-Kenudson M., Dacic S., Yeap B.Y., Shaw A., Barletta J.A., et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res 2009, 15:5216-5223.
    • (2009) Clin Cancer Res , vol.15 , pp. 5216-5223
    • Rodig, S.J.1    Mino-Kenudson, M.2    Dacic, S.3    Yeap, B.Y.4    Shaw, A.5    Barletta, J.A.6
  • 12
    • 70349336416 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
    • Shaw A.T., Yeap B.Y., Mino-Kenudson M., Digumarthy S.R., Costa D.B., Heist R.S., et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol 2009, 27:4247-4253.
    • (2009) J Clin Oncol , vol.27 , pp. 4247-4253
    • Shaw, A.T.1    Yeap, B.Y.2    Mino-Kenudson, M.3    Digumarthy, S.R.4    Costa, D.B.5    Heist, R.S.6
  • 13
    • 47649105190 scopus 로고    scopus 로고
    • EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas
    • Shinmura K., Kageyama S., Tao H., Bunai T., Suzuki M., Kamo T., et al. EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas. Lung Cancer 2008, 61:163-169.
    • (2008) Lung Cancer , vol.61 , pp. 163-169
    • Shinmura, K.1    Kageyama, S.2    Tao, H.3    Bunai, T.4    Suzuki, M.5    Kamo, T.6
  • 15
    • 63949086127 scopus 로고    scopus 로고
    • KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
    • Takeuchi K., Choi Y.L., Togashi Y., Soda M., Hatano S., Inamura K., et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res 2009, 15:3143-3149.
    • (2009) Clin Cancer Res , vol.15 , pp. 3143-3149
    • Takeuchi, K.1    Choi, Y.L.2    Togashi, Y.3    Soda, M.4    Hatano, S.5    Inamura, K.6
  • 16
    • 65249095599 scopus 로고    scopus 로고
    • The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
    • Wong D.W., Leung E.L., So K.K., Tam I.Y., Sihoe A.D., Cheng L., et al. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 2009, 115:1723-1733.
    • (2009) Cancer , vol.115 , pp. 1723-1733
    • Wong, D.W.1    Leung, E.L.2    So, K.K.3    Tam, I.Y.4    Sihoe, A.D.5    Cheng, L.6
  • 17
    • 74249123333 scopus 로고    scopus 로고
    • ALK gene rearrangements: a new therapeutic target in a molecularly defined subset of non-small cell lung cancer
    • Solomon B., Varella-Garcia M., Camidge D.R. ALK gene rearrangements: a new therapeutic target in a molecularly defined subset of non-small cell lung cancer. J Thorac Oncol 2009, 4:1450-1454.
    • (2009) J Thorac Oncol , vol.4 , pp. 1450-1454
    • Solomon, B.1    Varella-Garcia, M.2    Camidge, D.R.3
  • 19
    • 70350140489 scopus 로고    scopus 로고
    • Clinical activity observed in a phase I dose escalation trial of an oral c-met and ALK inhibitor, PF-02341966
    • Kwak E.L., Camidge D.R. Clinical activity observed in a phase I dose escalation trial of an oral c-met and ALK inhibitor, PF-02341966. J Clin Oncol 2009, 27.
    • (2009) J Clin Oncol , pp. 27
    • Kwak, E.L.1    Camidge, D.R.2
  • 20
    • 0024325299 scopus 로고
    • Primary mucinous adenocarcinoma of the lung with signet-ring cells: a histochemical comparison with signet-ring cell carcinomas of other sites
    • Kish J.K., Ro J.Y., Ayala A.G., McMurtrey M.J. Primary mucinous adenocarcinoma of the lung with signet-ring cells: a histochemical comparison with signet-ring cell carcinomas of other sites. Hum Pathol 1989, 20:1097-1102.
    • (1989) Hum Pathol , vol.20 , pp. 1097-1102
    • Kish, J.K.1    Ro, J.Y.2    Ayala, A.G.3    McMurtrey, M.J.4
  • 21
    • 3042760492 scopus 로고    scopus 로고
    • Primary lung carcinoma with signet-ring cell carcinoma components: clinicopathological analysis of 39 cases
    • Tsuta K., Ishii G., Yoh K., Nitadori J., Hasebe T., Nishiwaki Y., et al. Primary lung carcinoma with signet-ring cell carcinoma components: clinicopathological analysis of 39 cases. Am J Surg Pathol 2004, 28:868-874.
    • (2004) Am J Surg Pathol , vol.28 , pp. 868-874
    • Tsuta, K.1    Ishii, G.2    Yoh, K.3    Nitadori, J.4    Hasebe, T.5    Nishiwaki, Y.6
  • 22
    • 77950984567 scopus 로고    scopus 로고
    • Primary signet-ring carcinoma (SRC) of the lung: a population-based epidemiologic study of 262 cases with comparison to adenocarcinoma of the lung
    • Ou S.H., Ziogas A., Zell J.A. Primary signet-ring carcinoma (SRC) of the lung: a population-based epidemiologic study of 262 cases with comparison to adenocarcinoma of the lung. J Thorac Oncol 2010, 5:420-427.
    • (2010) J Thorac Oncol , vol.5 , pp. 420-427
    • Ou, S.H.1    Ziogas, A.2    Zell, J.A.3
  • 23
    • 0034756666 scopus 로고    scopus 로고
    • Primary signet ring cell adenocarcinomas of the lung: a clinicopathological study of 15 cases
    • Castro C.Y., Moran C.A., Flieder D.G., Suster S. Primary signet ring cell adenocarcinomas of the lung: a clinicopathological study of 15 cases. Histopathology 2001, 39:397-401.
    • (2001) Histopathology , vol.39 , pp. 397-401
    • Castro, C.Y.1    Moran, C.A.2    Flieder, D.G.3    Suster, S.4
  • 24
    • 0032919636 scopus 로고    scopus 로고
    • Primary signet-ring cell carcinoma of the lung: histochemical and immunohistochemical characterization
    • Hayashi H., Kitamura H., Nakatani Y., Inayama Y., Ito T., Kitamura H. Primary signet-ring cell carcinoma of the lung: histochemical and immunohistochemical characterization. Hum Pathol 1999, 30:378-383.
    • (1999) Hum Pathol , vol.30 , pp. 378-383
    • Hayashi, H.1    Kitamura, H.2    Nakatani, Y.3    Inayama, Y.4    Ito, T.5    Kitamura, H.6
  • 25
    • 0035185550 scopus 로고    scopus 로고
    • Primary signet-ring cell carcinoma of lung: immunohistochemical study and comparison with non-pulmonary signet-ring cell carcinomas
    • Merchant S.H., Amin M.B., Tamboli P., Ro J., Ordonez N.G., Ayala A.G., et al. Primary signet-ring cell carcinoma of lung: immunohistochemical study and comparison with non-pulmonary signet-ring cell carcinomas. Am J Surg Pathol 2001, 25:1515-1519.
    • (2001) Am J Surg Pathol , vol.25 , pp. 1515-1519
    • Merchant, S.H.1    Amin, M.B.2    Tamboli, P.3    Ro, J.4    Ordonez, N.G.5    Ayala, A.G.6
  • 26
    • 0030981538 scopus 로고    scopus 로고
    • Mucin-producing adenocarcinoma of the lung, with special reference to goblet cell type adenocarcinoma: immunohistochemical observation and Ki-ras gene mutation
    • Maeshima A., Miyagi A., Hirai T., Nakajima T. Mucin-producing adenocarcinoma of the lung, with special reference to goblet cell type adenocarcinoma: immunohistochemical observation and Ki-ras gene mutation. Pathol Int 1997, 47:454-460.
    • (1997) Pathol Int , vol.47 , pp. 454-460
    • Maeshima, A.1    Miyagi, A.2    Hirai, T.3    Nakajima, T.4
  • 27
    • 41149178982 scopus 로고    scopus 로고
    • Signet-ring cell carcinoma component in primary lung adenocarcinoma: potential prognostic factor
    • Iwasaki T., Ohta M., Lefor A.T., Kawahara K. Signet-ring cell carcinoma component in primary lung adenocarcinoma: potential prognostic factor. Histopathology 2008, 52:639-640.
    • (2008) Histopathology , vol.52 , pp. 639-640
    • Iwasaki, T.1    Ohta, M.2    Lefor, A.T.3    Kawahara, K.4
  • 28
    • 33645991850 scopus 로고    scopus 로고
    • Comparison of the immunophenotypes of signet-ring cell carcinoma, solid adenocarcinoma with mucin production, and mucinous bronchioloalveolar carcinoma of the lung characterized by the presence of cytoplasmic mucin
    • Tsuta K., Ishii G., Nitadori J., Murata Y., Kodama T., Nagai K., et al. Comparison of the immunophenotypes of signet-ring cell carcinoma, solid adenocarcinoma with mucin production, and mucinous bronchioloalveolar carcinoma of the lung characterized by the presence of cytoplasmic mucin. J Pathol 2006, 209:78-87.
    • (2006) J Pathol , vol.209 , pp. 78-87
    • Tsuta, K.1    Ishii, G.2    Nitadori, J.3    Murata, Y.4    Kodama, T.5    Nagai, K.6
  • 30
    • 79955473693 scopus 로고    scopus 로고
    • Protein expression and gene rearrangement of ALK in non-small cell lung carcinomas
    • Paik J., Choe J., Chung J. Protein expression and gene rearrangement of ALK in non-small cell lung carcinomas. Mod Pathol 2010, 23:411A.
    • (2010) Mod Pathol , vol.23
    • Paik, J.1    Choe, J.2    Chung, J.3
  • 31
    • 51049110952 scopus 로고    scopus 로고
    • Prospective study of the accuracy of EGFR mutational analysis by high-resolution melting analysis in small samples obtained from patients with non-small cell lung cancer
    • Fukui T., Ohe Y., Tsuta K., Furuta K., Sakamoto H., Takano T., et al. Prospective study of the accuracy of EGFR mutational analysis by high-resolution melting analysis in small samples obtained from patients with non-small cell lung cancer. Clin Cancer Res 2008, 14:4751-4757.
    • (2008) Clin Cancer Res , vol.14 , pp. 4751-4757
    • Fukui, T.1    Ohe, Y.2    Tsuta, K.3    Furuta, K.4    Sakamoto, H.5    Takano, T.6
  • 32
    • 34547111048 scopus 로고    scopus 로고
    • Distinctive evaluation of nonmucinous and mucinous subtypes of bronchioloalveolar carcinomas in EGFR and K-ras gene-mutation analyses for Japanese lung adenocarcinomas: confirmation of the correlations with histologic subtypes and gene mutations
    • Sakuma Y., Matsukuma S., Yoshihara M., Nakamura Y., Noda K., Nakayama H., et al. Distinctive evaluation of nonmucinous and mucinous subtypes of bronchioloalveolar carcinomas in EGFR and K-ras gene-mutation analyses for Japanese lung adenocarcinomas: confirmation of the correlations with histologic subtypes and gene mutations. Am J Clin Pathol 2007, 128:100-108.
    • (2007) Am J Clin Pathol , vol.128 , pp. 100-108
    • Sakuma, Y.1    Matsukuma, S.2    Yoshihara, M.3    Nakamura, Y.4    Noda, K.5    Nakayama, H.6
  • 33
    • 0025411206 scopus 로고
    • Primary signet-ring cell carcinoma of the lung
    • Sarma D.P., Hoffmann E.O. Primary signet-ring cell carcinoma of the lung. Hum Pathol 1990, 21:459-460.
    • (1990) Hum Pathol , vol.21 , pp. 459-460
    • Sarma, D.P.1    Hoffmann, E.O.2
  • 34
    • 4344634453 scopus 로고    scopus 로고
    • P63 expression in assessment of bronchioloalveolar proliferation of the lung
    • Sheikh H.A., Fuhrer K., Cieply K., Yousem S. p63 expression in assessment of bronchioloalveolar proliferation of the lung. Mod Pathol 2004, 17:1134-1140.
    • (2004) Mod Pathol , vol.17 , pp. 1134-1140
    • Sheikh, H.A.1    Fuhrer, K.2    Cieply, K.3    Yousem, S.4
  • 35
    • 42549103131 scopus 로고    scopus 로고
    • Immunohistochemical detection of XIAP and p63 in adenomatous hyperplasia, atypical adenomatous hyperplasia, bronchioloalveolar carcinoma and well-differentiated adenocarcinoma
    • Wu M., Orta L., Gil J., Li G., Hu A., Burstein D.E. Immunohistochemical detection of XIAP and p63 in adenomatous hyperplasia, atypical adenomatous hyperplasia, bronchioloalveolar carcinoma and well-differentiated adenocarcinoma. Mod Pathol 2008, 21:553-558.
    • (2008) Mod Pathol , vol.21 , pp. 553-558
    • Wu, M.1    Orta, L.2    Gil, J.3    Li, G.4    Hu, A.5    Burstein, D.E.6
  • 36
    • 79551510117 scopus 로고    scopus 로고
    • Expression of squamous markers in lung adenocarcinoma: clinicopathologic and molecular correlates, and implications for differentiation from squamous cell carcinoma
    • Ang D., Ghaffar H., Zakowski M., Teruya-Feldstein J., Moreira A., Rekhtman N. Expression of squamous markers in lung adenocarcinoma: clinicopathologic and molecular correlates, and implications for differentiation from squamous cell carcinoma. Mod Pathol 2010, 23:397A.
    • (2010) Mod Pathol , vol.23
    • Ang, D.1    Ghaffar, H.2    Zakowski, M.3    Teruya-Feldstein, J.4    Moreira, A.5    Rekhtman, N.6
  • 37
    • 71149109524 scopus 로고    scopus 로고
    • Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma
    • Nakayama T., Miyabe S., Okabe M., Sakuma H., Ijichi K., Hasegawa Y., et al. Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma. Mod Pathol 2009, 22:1575-1581.
    • (2009) Mod Pathol , vol.22 , pp. 1575-1581
    • Nakayama, T.1    Miyabe, S.2    Okabe, M.3    Sakuma, H.4    Ijichi, K.5    Hasegawa, Y.6


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