-
1
-
-
34548577764
-
Demenz mit Lewy-korperchen. Besserung unter therapie mit einem acetylcholinesteraseinhibitor
-
DOI 10.1007/s00115-007-2277-1
-
Omerovic M, Teipel SJ, Hampel T. Dementia with Lewy bodies. Clinical improvement under treatment with an acetylcholinesterase inhibitor]. Nervenarzt 2007; 78: 1052-1057. (Pubitemid 47396477)
-
(2007)
Nervenarzt
, vol.78
, Issue.9
, pp. 1052-1057
-
-
Omerovic, M.1
Teipel, S.J.2
Hampel, T.3
-
2
-
-
33645471999
-
Contemporary issues in the treatment of Alzheimer's disease: Tangible benefits of current therapies
-
quiz 23
-
Tariot PN. Contemporary issues in the treatment of Alzheimer's disease: tangible benefits of current therapies. J Clin Psychiatry 2006; 67(Suppl 3): 15-22; quiz 23.
-
(2006)
J Clin Psychiatry
, vol.67
, Issue.SUPPL. 3
, pp. 15-22
-
-
Tariot, P.N.1
-
3
-
-
33645558594
-
Clinical trials in mild cognitive impairment: Lessons for the future
-
Jelic V, Kivipelto M, Winblad B. Clinical trials in mild cognitive impairment: lessons for the future. J Neurol Neurosurg Psychiatry 2006; 77: 429-438.
-
(2006)
J Neurol Neurosurg Psychiatry
, vol.77
, pp. 429-438
-
-
Jelic, V.1
Kivipelto, M.2
Winblad, B.3
-
4
-
-
36849078870
-
Cholinesterase inhibitors in mild cognitive impairment: A systematic review of randomised trials
-
Raschetti R, Albanese E, Vanacore N, Maggini M. Cholinesterase inhibitors in mild cognitive impairment: a systematic review of randomised trials. PLoS Med 2007; 4: e338.
-
(2007)
PLoS Med
, vol.4
-
-
Raschetti, R.1
Albanese, E.2
Vanacore, N.3
Maggini, M.4
-
5
-
-
0034944798
-
Antihistamine agent dimebon as a novel neuroprotector and a cognition enhancer
-
Bachurin S, Bukatina E, Lermontova N, Tkachenko S, Afanasiev A, Grigoriev V et al. Antihistamine agent Dimebon as a novel neuroprotector and a cognition enhancer. Ann N Y Acad Sci 2001; 939: 425-435. (Pubitemid 32620096)
-
(2001)
Annals of the New York Academy of Sciences
, vol.939
, pp. 425-435
-
-
Bachurin, S.1
Bukatina, E.2
Lermontova, N.3
Tkachenko, S.4
Afanasiev, A.5
Grigoriev, V.6
Grigorieva, I.7
Ivanov, Yu.8
Sablin, S.9
Zefirov, N.10
-
6
-
-
0020643057
-
Action of dimebon on histamine receptors
-
Matveeva IA. Action of dimebon on histamine receptors. Farmakol Toksikol 1983; 46: 27-29. (Pubitemid 13038960)
-
(1983)
Farmakologiya i Toksikologiya
, vol.46
, Issue.4
, pp. 27-29
-
-
Matveeva, I.A.1
-
8
-
-
47149108940
-
Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-To-Moderate Alzheimer's disease: A randomised, double-Blind, placebo-Controlled study
-
DOI 10.1016/S0140-6736(08)61074-0, PII S0140673608610740
-
Doody RS, Gavrilova SI, Sano M, Thomas RG, Aisen PS, Bachurin SO et al. Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study. Lancet 2008; 372: 207-215. (Pubitemid 351978110)
-
(2008)
The Lancet
, vol.372
, Issue.9634
, pp. 207-215
-
-
Doody, R.S.1
Gavrilova, S.I.2
Sano, M.3
Thomas, R.G.4
Aisen, P.S.5
Bachurin, S.O.6
Seely, L.7
Hung, D.8
-
9
-
-
76149084493
-
A randomized, placebo-controlled trial of latrepirdine in Huntington disease
-
Kieburtz K, McDermott MP, Voss TS, Corey-Bloom J, Deuel LM, Dorsey ER et al. A randomized, placebo-controlled trial of latrepirdine in Huntington disease. Arch Neurol 2010; 67: 154-160.
-
(2010)
Arch Neurol
, vol.67
, pp. 154-160
-
-
Kieburtz, K.1
McDermott, M.P.2
Voss, T.S.3
Corey-Bloom, J.4
Deuel, L.M.5
Dorsey, E.R.6
-
10
-
-
84890225049
-
-
Contact: An Alzheimer's Disease Investigational Trial. Available at (accessed on 2010)
-
Contact: An Alzheimer's Disease Investigational Trial. Available at: http://www. contactstudy.com/ (accessed on 2010).
-
-
-
-
12
-
-
77950541917
-
Mechanism matters
-
Editorial
-
Editorial. Mechanism matters. Nat Med 2010; 16: 347.
-
(2010)
Nat Med
, vol.16
, pp. 347
-
-
-
13
-
-
79958026811
-
Learning from failure
-
Editorial
-
Editorial. Learning from failure. Nat Rev Drug Discov 2010; 9: 499.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 499
-
-
-
14
-
-
67650128713
-
Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds
-
Bachurin SO, Ustyugov AA, Peters O, Shelkovnikova TA, Buchman VL, Ninkina NN. Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds. Dokl Biochem Biophys 2009; 428: 235-238.
-
(2009)
Dokl Biochem Biophys
, vol.428
, pp. 235-238
-
-
Bachurin, S.O.1
Ustyugov, A.A.2
Peters, O.3
Shelkovnikova, T.A.4
Buchman, V.L.5
Ninkina, N.N.6
-
15
-
-
0033635668
-
Dimebon improves learning in animals with experimental Alzheimer's disease
-
Lermontova NN, Lukoyanov NV, Serkova TP, Lukoyanova EA, Bachurin SO. Dimebon improves learning in animals with experimental Alzheimer's disease. Bull Exp Biol Med 2000; 129: 544-546.
-
(2000)
Bull Exp Biol Med
, vol.129
, pp. 544-546
-
-
Lermontova, N.N.1
Lukoyanov, N.V.2
Serkova, T.P.3
Lukoyanova, E.A.4
Bachurin, S.O.5
-
16
-
-
55349083365
-
Evaluation of Dimebon in cellular model of Huntington's disease
-
Wu J, Li Q, Bezprozvanny I. Evaluation of Dimebon in cellular model of Huntington's disease. Mol Neurodegener 2008; 3: 15.
-
(2008)
Mol Neurodegener
, vol.3
, pp. 15
-
-
Wu, J.1
Li, Q.2
Bezprozvanny, I.3
-
17
-
-
77949769167
-
From antiallergic to anti-Alzheimer's: Molecular pharmacology of Dimebon
-
Okun I, Tkachenko SE, Khvat A, Mitkin O, Kazey V, Ivachtchenko AV. From antiallergic to anti-Alzheimer's: molecular pharmacology of Dimebon. Curr Alzheimer Res 2010; 7: 97-112.
-
(2010)
Curr Alzheimer Res
, vol.7
, pp. 97-112
-
-
Okun, I.1
Tkachenko, S.E.2
Khvat, A.3
Mitkin, O.4
Kazey, V.5
Ivachtchenko, A.V.6
-
18
-
-
77956214193
-
Dimebon (latrepirdine) enhances mitochondrial function and protects neuronal cells from death
-
Zhang S, Hedskog L, Petersen CA, Winblad B, Ankarcrona M. Dimebon (latrepirdine) enhances mitochondrial function and protects neuronal cells from death. J Alzheimers Dis 2010; 21: 389-402.
-
(2010)
J Alzheimers Dis
, vol.21
, pp. 389-402
-
-
Zhang, S.1
Hedskog, L.2
Petersen, C.A.3
Winblad, B.4
Ankarcrona, M.5
-
19
-
-
77954266958
-
Discovery of a proneurogenic, neuroprotective chemical
-
Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM et al. Discovery of a proneurogenic, neuroprotective chemical. Cell 2010; 142: 39-51.
-
(2010)
Cell
, vol.142
, pp. 39-51
-
-
Pieper, A.A.1
Xie, S.2
Capota, E.3
Estill, S.J.4
Zhong, J.5
Long, J.M.6
-
20
-
-
84867058325
-
Dimebon alters hippocampal amyloid pathology in 3-Tg-AD mice
-
Perez SE, Nadeem M, Sadleir KR, Matras J, Kelley CM, Counts SE et al. Dimebon alters hippocampal amyloid pathology in 3-Tg-AD mice. Int J Physiol Pathophysiol Pharmacol 2012; 4: 115-127.
-
(2012)
Int J Physiol Pathophysiol Pharmacol
, vol.4
, pp. 115-127
-
-
Perez, S.E.1
Nadeem, M.2
Sadleir, K.R.3
Matras, J.4
Kelley, C.M.5
Counts, S.E.6
-
21
-
-
84881158430
-
Latrepirdine stimulates autophagy and reduces accumulation of alpha-synuclein in cells and in mouse brain
-
Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH et al. Latrepirdine stimulates autophagy and reduces accumulation of alpha-synuclein in cells and in mouse brain. Mol Psychiatry 2012; 18: 882-888.
-
(2012)
Mol Psychiatry
, vol.18
, pp. 882-888
-
-
Steele, J.W.1
Ju, S.2
Lachenmayer, M.L.3
Liken, J.4
Stock, A.5
Kim, S.H.6
-
22
-
-
84881178228
-
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model
-
Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH et al. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Mol Psychiatry 2012; 18: 889-897.
-
(2012)
Mol Psychiatry
, vol.18
, pp. 889-897
-
-
Steele, J.W.1
Lachenmayer, M.L.2
Ju, S.3
Stock, A.4
Liken, J.5
Kim, S.H.6
-
23
-
-
47149116336
-
Dimebon in Alzheimer's disease:Old drug for new indication
-
DOI 10.1016/S0140-6736(08)61046-6, PII S0140673608610466
-
Burns A, Jacoby R. Dimebon in Alzheimer's disease: old drug for new indication. Lancet 2008; 372: 179-180. (Pubitemid 351978088)
-
(2008)
The Lancet
, vol.372
, Issue.9634
, pp. 179-180
-
-
Burns, A.1
Jacoby, R.2
-
24
-
-
0029284227
-
Antiarrhythmic properties of dimebone
-
Galenko-Iaroshevskii PA, Chekanova OA, Skibitskii VV, Bartashevich VV, Khankoeva AI, Poliashova TI. Antiarrhythmic properties of dimebone. Biull Eksp Biol Med 1995; 119: 375-377.
-
(1995)
Biull Eksp Biol Med
, vol.119
, pp. 375-377
-
-
Galenko-Iaroshevskii, P.A.1
Chekanova, O.A.2
Skibitskii, V.V.3
Bartashevich, V.V.4
Khankoeva, A.I.5
Poliashova, T.I.6
-
25
-
-
0030133907
-
Effect of dimebone on coronary blood flow and myocardial contractibility
-
Galenko-Iaroshevskii PA, Sheikh-Zade Iu R, Chekanova OA, Melkumova ER, Bartashevich VV, Khankoeva AI. Effect of dimebone on coronary blood flow and myocardial contractibility. Biull Eksp Biol Med 1996; 121: 506-508.
-
(1996)
Biull Eksp Biol Med
, vol.121
, pp. 506-508
-
-
Galenko-Iaroshevskii, P.A.1
Sheikh-Zade Iu, R.2
Chekanova, O.A.3
Melkumova, E.R.4
Bartashevich, V.V.5
Khankoeva, A.I.6
-
26
-
-
0035210592
-
6 receptors in memory formation
-
Meneses A. Role of 5-HT6 receptors in memory formation. Drug News Perspect 2001; 14: 396-400. (Pubitemid 33140705)
-
(2001)
Drug News and Perspectives
, vol.14
, Issue.7
, pp. 396-400
-
-
Meneses, A.1
-
27
-
-
0028261434
-
Binding of typical and atypical antipsychotic agents to 5- hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors
-
Roth BL, Craigo SC, Choudhary MS, Uluer A, Monsma Jr. FJ, Shen Y et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther 1994; 268: 1403-1410. (Pubitemid 24100360)
-
(1994)
Journal of Pharmacology and Experimental Therapeutics
, vol.268
, Issue.3
, pp. 1403-1410
-
-
Roth, B.L.1
Craigo, S.C.2
Choudhary, M.S.3
Uluer, A.4
Monsma Jr., F.J.5
Shen, Y.6
Meltzer, H.Y.7
Sibley, D.R.8
-
28
-
-
0025273543
-
2+ influx in cultured hippocampal neurons
-
DOI 10.1016/0896-6273(90)90447-N
-
Mattson MP. Antigenic changes similar to those seen in neurofibrillary tangles are elicited by glutamate and Ca2 influx in cultured hippocampal neurons. Neuron 1990; 4: 105-117. (Pubitemid 20149759)
-
(1990)
Neuron
, vol.4
, Issue.1
, pp. 105-117
-
-
Mattson, M.P.1
-
29
-
-
0025318155
-
Neuron-specific and state-specific differences in calcium homeostasis regulate the generation and degeneration of neuronal architecture
-
DOI 10.1016/0896-6273(90)90451-K
-
Mills LR, Kater SB. Neuron-specific and state-specific differences in calcium homeostasis regulate the generation and degeneration of neuronal architecture. Neuron 1990; 4: 149-163. (Pubitemid 20149763)
-
(1990)
Neuron
, vol.4
, Issue.1
, pp. 149-163
-
-
Mills, L.R.1
Kater, S.B.2
-
30
-
-
0033180601
-
Neuroprotective approaches in experimental models of β-amyloid neurotoxicity: Relevance to Alzheimer's disease
-
DOI 10.1016/S0278-5846(99)00058-5, PII S0278584699000585
-
Harkany T, Hortobagyi T, Sasvari M, Konya C, Penke B, Luiten PG et al. Neuroprotective approaches in experimental models of beta-amyloid neurotoxicity: relevance to Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry 1999; 23: 963-1008. (Pubitemid 29468909)
-
(1999)
Progress in Neuro-Psychopharmacology and Biological Psychiatry
, vol.23
, Issue.6
, pp. 963-1008
-
-
Harkany, T.1
Hortobagyi, T.2
Sasvari, M.3
Konya, C.4
Penke, B.5
Luiten, P.G.M.6
Nyakas, C.7
-
31
-
-
0031048111
-
Psychotogenicity and N-methyl-D-aspartate receptor antagonism: Implications for neuroprotective pharmacotherapy
-
DOI 10.1016/S0006-3223(96)00047-9, PII S0006322396000479
-
Kornhuber J, Weller M. Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy. Biol Psychiatry 1997; 41: 135-144. (Pubitemid 27062653)
-
(1997)
Biological Psychiatry
, vol.41
, Issue.2
, pp. 135-144
-
-
Kornhuber, J.1
Weller, M.2
-
32
-
-
0033796256
-
Low affinity use-dependent NMDA receptor antagonists show promise for clinical development
-
Palmer GC, Widzowski D. Low affinity use-dependent NMDA receptor antagonists show promise for clinical development. Amino Acids 2000; 19: 151-155.
-
(2000)
Amino Acids
, vol.19
, pp. 151-155
-
-
Palmer, G.C.1
Widzowski, D.2
-
33
-
-
3242887701
-
Comparative study of action mechanisms of dimebon and memantine on AMPA- and NMDA-subtypes glutamate receptors in rat cerebral neurons
-
DOI 10.1023/B:BEBM.0000017097.75818.14
-
Grigorev VV, Dranyi OA, Bachurin SO. Comparative study of action mechanisms of dimebon and memantine on AMPA- and NMDA-subtypes glutamate receptors in rat cerebral neurons. Bull Exp Biol Med 2003; 136: 474-477. (Pubitemid 39137308)
-
(2003)
Bulletin of Experimental Biology and Medicine
, vol.136
, Issue.5
, pp. 474-477
-
-
Grigor'ev, V.V.1
Dranyi, O.A.2
Bachurin, S.O.3
-
34
-
-
0035146803
-
The physiology of brain histamine
-
DOI 10.1016/S0301-0082(00)00039-3, PII S0301008200000393
-
Brown RE, Stevens DR, Haas HL. The physiology of brain histamine. Prog Neurobiol 2001; 63: 637-672. (Pubitemid 32119421)
-
(2001)
Progress in Neurobiology
, vol.63
, Issue.6
, pp. 637-672
-
-
Brown, R.E.1
Stevens, D.R.2
Haas, H.L.3
-
35
-
-
0037713338
-
Mitochondria as a target for neurotoxins and neuroprotective agents
-
Bachurin SO, Shevtsova EP, Kireeva EG, Oxenkrug GF, Sablin SO. Mitochondria as a target for neurotoxins and neuroprotective agents. Ann N Y Acad Sci 2003; 993: 334-344, discussion 345-339. (Pubitemid 36808462)
-
(2003)
Annals of the New York Academy of Sciences
, vol.993
, pp. 334-344
-
-
Bachurin, S.O.1
Shevtsova, E.P.2
Kireeva, E.G.3
Oxenkrug, G.F.4
Sablin, S.O.5
-
36
-
-
0036218369
-
2+ channels
-
Lermontova NN, Redkozubov AE, Shevtsova EF, Serkova TP, Kireeva EG, Bachurin SO. Dimebon and tacrine inhibit neurotoxic action of beta-amyloid in culture and block L-type Ca(2) channels. Bull Exp Biol Med 2001; 132: 1079-1083. (Pubitemid 34295938)
-
(2001)
Bulletin of Experimental Biology and Medicine
, vol.132
, Issue.5
, pp. 1079-1083
-
-
Lermontova, N.N.1
Redkozubov, A.E.2
Shevtsova, E.F.3
Serkova, T.P.4
Kireeva, E.G.5
Bachurin, S.O.6
-
37
-
-
24944450690
-
Neuron specific α-adrenergic receptor expression in human cerebellum: Implications for emerging cerebellar roles in neurologic disease
-
DOI 10.1016/j.neuroscience.2005.06.021, PII S0306452205006846
-
Schambra UB, Mackensen GB, Stafford-Smith M, Haines DE, Schwinn DA. Neuron specific alpha-adrenergic receptor expression in human cerebellum: implications for emerging cerebellar roles in neurologic disease. Neuroscience 2005; 135: 507-523. (Pubitemid 41317388)
-
(2005)
Neuroscience
, vol.135
, Issue.2
, pp. 507-523
-
-
Schambra, U.B.1
Mackensen, G.B.2
Stafford-Smith, M.3
Haines, D.E.4
Schwinn, D.A.5
-
38
-
-
33646754515
-
Therapeutic targets: Progress of their exploration and investigation of their characteristics
-
Zheng CJ, Han LY, Yap CW, Ji ZL, Cao ZW, Chen YZ. Therapeutic targets: progress of their exploration and investigation of their characteristics. Pharmacol Rev 2006; 58: 259-279.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 259-279
-
-
Zheng, C.J.1
Han, L.Y.2
Yap, C.W.3
Ji, Z.L.4
Cao, Z.W.5
Chen, Y.Z.6
-
39
-
-
0031596301
-
5-HT(2A) and 5-HT(2C) receptor polymorphisms and psychopathology in late onset Alzheimer's disease
-
DOI 10.1093/hmg/7.9.1507
-
Holmes C, Arranz MJ, Powell JF, Collier DA, Lovestone S. 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease. Hum Mol Genet 1998; 7: 1507-1509. (Pubitemid 28429933)
-
(1998)
Human Molecular Genetics
, vol.7
, Issue.9
, pp. 1507-1509
-
-
Holmes, C.1
Arranz, M.J.2
Powell, J.F.3
Collier, D.A.4
Lovestone, S.5
-
40
-
-
0034749093
-
Association analysis of HTR6 and HTR2A polymorphisms in sporadic Alzheimer's disease
-
DOI 10.1007/s007020170007
-
Thome J, Retz W, Baader M, Pesold B, Hu M, Cowen M et al. Association analysis of HTR6 and HTR2A polymorphisms in sporadic Alzheimer's disease. J Neural Transm 2001; 108: 1175-1180. (Pubitemid 33022767)
-
(2001)
Journal of Neural Transmission
, vol.108
, Issue.10
, pp. 1175-1180
-
-
Thome, J.1
Retz, W.2
Baader, M.3
Pesold, B.4
Hu, M.5
Cowen, M.6
Durany, N.7
Adler, G.8
Henn, F.A.9
Rosler, M.10
-
41
-
-
69349100072
-
Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities
-
Schaffhauser H, Mathiasen JR, Dicamillo A, Huffman MJ, Lu LD, McKenna BA et al. Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities. Biochem Pharmacol 2009; 78: 1035-1042.
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 1035-1042
-
-
Schaffhauser, H.1
Mathiasen, J.R.2
Dicamillo, A.3
Huffman, M.J.4
Lu, L.D.5
McKenna, B.A.6
-
42
-
-
0022726686
-
Neurotransmitter mechanisms of an antihistamine agent dimebone action on the brain
-
Shadurskaia SK, Khomenko AI, Pereverzev VA, Balaklevskii AI. Neuromediator mechanisms of the effect of the antihistamine agent dimebone on the brain. Biull Eksp Biol Med 1986; 101: 700-702. (Pubitemid 16086204)
-
(1986)
Byulleten Eksperimentalnoi Biologii i Meditsiny
, vol.101
, Issue.6
, pp. 700-702
-
-
Shadurskaya, S.K.1
Khomenko, A.I.2
Pereverzev, V.A.3
Balakleevsky, A.I.4
-
43
-
-
0027504493
-
The effect of antihistaminic preparations on the binding of labelled mepyramine, ketanserin and quinuclidinyl benzilate in the rat brain
-
Gankina EM, Porodenko NV, Kondratenko TI, Severin ES, Kaminka ME, Mashkovskii MD. The effect of antihistaminic preparations on the binding of labelled mepyramine, ketanserin and quinuclidinyl benzilate in the rat brain. Eksp Klin Farmakol 1993; 56: 22-24.
-
(1993)
Eksp Klin Farmakol
, vol.56
, pp. 22-24
-
-
Gankina, E.M.1
Porodenko, N.V.2
Kondratenko, T.I.3
Severin, E.S.4
Kaminka, M.E.5
Mashkovskii, M.D.6
-
44
-
-
0029893858
-
The AF64A model of cholinergic hypofunction: An update
-
DOI 10.1016/0024-3205(96)00185-3
-
Hanin I. The AF64A model of cholinergic hypofunction: an update. Life Sci 1996; 58: 1955-1964. (Pubitemid 26160433)
-
(1996)
Life Sciences
, vol.58
, Issue.22
, pp. 1955-1964
-
-
Hanin, I.1
-
45
-
-
84861141817
-
Dimebon attenuates methamphetamine, but not MPTP, striatal dopamine depletion
-
Geldenhuys WJ, Darvesh AS, Dluzen DE. Dimebon attenuates methamphetamine, but not MPTP, striatal dopamine depletion. Neurochem Int 2012; 60: 806-808.
-
(2012)
Neurochem Int
, vol.60
, pp. 806-808
-
-
Geldenhuys, W.J.1
Darvesh, A.S.2
Dluzen, D.E.3
-
46
-
-
79952901355
-
Dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory memory tasks in mice
-
Vignisse J, Steinbusch HW, Bolkunov A, Nunes J, Santos AI, Grandfils C et al. Dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory memory tasks in mice. Prog Neuropsychopharmacol Biol Psychiatry 2011; 35: 510-522.
-
(2011)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.35
, pp. 510-522
-
-
Vignisse, J.1
Steinbusch, H.W.2
Bolkunov, A.3
Nunes, J.4
Santos, A.I.5
Grandfils, C.6
-
47
-
-
84878018261
-
The age-related gliosis and accompanying deficit in spatial learning are unaffected by Dimebon
-
Cowley TR, Gonzalez-Reyes RE, Richardson JC, Virley D, Upton N, Lynch MA. The age-related gliosis and accompanying deficit in spatial learning are unaffected by Dimebon. Neurochem Res 2012; 38: 1190-1195.
-
(2012)
Neurochem Res
, vol.38
, pp. 1190-1195
-
-
Cowley, T.R.1
Gonzalez-Reyes, R.E.2
Richardson, J.C.3
Virley, D.4
Upton, N.5
Lynch, M.A.6
-
48
-
-
80052559894
-
The acute effects of dimebolin, a potential Alzheimer's disease treatment, on working memory in rhesus monkeys
-
Webster SJ, Wilson CA, Lee CH, Mohler EG, Terry Jr AV, Buccafusco JJ. The acute effects of dimebolin, a potential Alzheimer's disease treatment, on working memory in rhesus monkeys. Br J Pharmacol 2011; 164: 970-978.
-
(2011)
Br J Pharmacol
, vol.164
, pp. 970-978
-
-
Webster, S.J.1
Wilson, C.A.2
Lee, C.H.3
Mohler, E.G.4
Terry Jr., A.V.5
Buccafusco, J.J.6
-
49
-
-
77952387355
-
Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate receptor antagonism
-
Giorgetti M, Gibbons JA, Bernales S, Alfaro IE, Drieu La Rochelle C, Cremers T et al. Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate receptor antagonism. J Pharmacol Exp Ther 2010; 333: 748-757.
-
(2010)
J Pharmacol Exp Ther
, vol.333
, pp. 748-757
-
-
Giorgetti, M.1
Gibbons, J.A.2
Bernales, S.3
Alfaro, I.E.4
Drieu La Rochelle, C.5
Cremers, T.6
-
50
-
-
33751162382
-
6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models
-
DOI 10.1016/j.ejphar.2006.09.049, PII S0014299906010454
-
Hirst WD, Stean TO, Rogers DC, Sunter D, Pugh P, Moss SF et al. SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models. Eur J Pharmacol 2006; 553: 109-119. (Pubitemid 44779592)
-
(2006)
European Journal of Pharmacology
, vol.553
, Issue.1-3
, pp. 109-119
-
-
Hirst, W.D.1
Stean, T.O.2
Rogers, D.C.3
Sunter, D.4
Pugh, P.5
Moss, S.F.6
Bromidge, S.M.7
Riley, G.8
Smith, D.R.9
Bartlett, S.10
Heidbreder, C.A.11
Atkins, A.R.12
Lacroix, L.P.13
Dawson, L.A.14
Foley, A.G.15
Regan, C.M.16
Upton, N.17
-
51
-
-
84872301584
-
Latrepirdine (Dimebon) enhances autophagy and reduces intracellular GFPAbeta42 levels in yeast
-
Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML et al. Latrepirdine (Dimebon) enhances autophagy and reduces intracellular GFPAbeta42 levels in yeast. J Alzheimers Dis 2012; 32: 949-967.
-
(2012)
J Alzheimers Dis
, vol.32
, pp. 949-967
-
-
Bharadwaj, P.R.1
Verdile, G.2
Barr, R.K.3
Gupta, V.4
Steele, J.W.5
Lachenmayer, M.L.6
-
52
-
-
0035877756
-
Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695
-
DOI 10.1074/jbc.M100710200
-
Chishti MA, Yang DS, Janus C, Phinney AL, Horne P, Pearson J et al. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem 2001; 276: 21562-21570. (Pubitemid 37413154)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.24
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.-S.2
Janus, C.3
Phinney, A.L.4
Horne, P.5
Pearson, J.6
Strome, R.7
Zuker, N.8
Loukides, J.9
French, J.10
Turner, S.11
Lozza, G.12
Grilli, M.13
Kunicki, S.14
Morissette, C.15
Paquette, J.16
Gervais, F.17
Bergeron, C.18
Fraser, P.E.19
Carlson, G.A.20
St. George-Hyslop, P.21
Westawaya, D.22
more..
-
53
-
-
78651481652
-
Preclinical study of dimebon on beta-amyloid-mediated neuropathology in Alzheimer's disease
-
Wang J, Ferruzzi MG, Varghese M, Qian X, Cheng A, Xie M et al. Preclinical study of dimebon on beta-amyloid-mediated neuropathology in Alzheimer's disease. Mol Neurodegener 2011; 6: 7.
-
(2011)
Mol Neurodegener
, vol.6
, pp. 7
-
-
Wang, J.1
Ferruzzi, M.G.2
Varghese, M.3
Qian, X.4
Cheng, A.5
Xie, M.6
-
54
-
-
79960558362
-
Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice
-
Shelkovnikova TA, Ustyugov AA, Millership S, Peters O, Anichtchik O, Spillantini MG et al. Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice. Neurodegener Dis 2011; 8: 430-437.
-
(2011)
Neurodegener Dis
, vol.8
, pp. 430-437
-
-
Shelkovnikova, T.A.1
Ustyugov, A.A.2
Millership, S.3
Peters, O.4
Anichtchik, O.5
Spillantini, M.G.6
-
55
-
-
84867628671
-
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease
-
De Jesus-Cortes H, Xu P, Drawbridge J, Estill SJ, Huntington P, Tran S et al. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease. Proc Natl Acad Sci USA 2012; 109: 17010-17015.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 17010-17015
-
-
De Jesus-Cortes, H.1
Xu, P.2
Drawbridge, J.3
Estill, S.J.4
Huntington, P.5
Tran, S.6
-
56
-
-
84861456266
-
Dimebon slows progression of proteinopathy in gamma-synuclein transgenic mice
-
Bachurin SO, Shelkovnikova TA, Ustyugov AA, Peters O, Khritankova I, Afanasieva MA et al. dimebon slows progression of proteinopathy in gamma-synuclein transgenic mice. Neurotoxicol Res 2012; 22: 33-42.
-
(2012)
Neurotoxicol Res
, vol.22
, pp. 33-42
-
-
Bachurin, S.O.1
Shelkovnikova, T.A.2
Ustyugov, A.A.3
Peters, O.4
Khritankova, I.5
Afanasieva, M.A.6
-
57
-
-
84867639321
-
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis
-
Tesla R, Wolf HP, Xu P, Drawbridge J, Estill SJ, Huntington P et al. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis. Proc Natl Acad Sci USA 2012; 109: 17016-17021.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 17016-17021
-
-
Tesla, R.1
Wolf, H.P.2
Xu, P.3
Drawbridge, J.4
Estill, S.J.5
Huntington, P.6
-
58
-
-
79952902540
-
APOE dependent-association of PPAR-gamma genetic variants with Alzheimer's disease risk
-
e541-546
-
Combarros O, Rodriguez-Rodriguez E, Mateo I, Vazquez-Higuera JL, Infante J, Berciano J et al. APOE dependent-association of PPAR-gamma genetic variants with Alzheimer's disease risk. Neurobiol Aging 2011; 32: 547 e541-546.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 547
-
-
Combarros, O.1
Rodriguez-Rodriguez, E.2
Mateo, I.3
Vazquez-Higuera, J.L.4
Infante, J.5
Berciano, J.6
-
59
-
-
39149091398
-
Multi-target-directed ligands to combat neurodegenerative diseases
-
DOI 10.1021/jm7009364
-
Cavalli A, Bolognesi ML, Minarini A, Rosini M, Tumiatti V, Recanatini M et al. Multitarget- directed ligands to combat neurodegenerative diseases. J Med Chem 2008; 51: 347-372. (Pubitemid 351252260)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.3
, pp. 347-372
-
-
Cavalli, A.1
Bolognesi, M.L.2
Minarini, A.3
Rosini, M.4
Tumiatti, V.5
Recanatini, M.6
Melchiorre, C.7
-
60
-
-
17844364259
-
Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease: FDG-PET studies in MCI and AD
-
DOI 10.1007/s00259-005-1762-7
-
Mosconi L. Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD. Eur J Nucl Med Mol Imaging 2005; 32: 486-510. (Pubitemid 40591181)
-
(2005)
European Journal of Nuclear Medicine and Molecular Imaging
, vol.32
, Issue.4
, pp. 486-510
-
-
Mosconi, L.1
-
61
-
-
18244390483
-
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
-
DOI 10.1002/ana.20474
-
Bubber P, Haroutunian V, Fisch G, Blass JP, Gibson GE. Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Ann Neurol 2005; 57: 695-703. (Pubitemid 40628858)
-
(2005)
Annals of Neurology
, vol.57
, Issue.5
, pp. 695-703
-
-
Bubber, P.1
Haroutunian, V.2
Fisch, G.3
Blass, J.P.4
Gibson, G.E.5
-
62
-
-
3042513691
-
Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aβ toxicity
-
DOI 10.1111/j.1471-4159.2004.02438.x
-
Cardoso SM, Santana I, Swerdlow RH, Oliveira CR. Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity. J Neurochem 2004; 89: 1417-1426. (Pubitemid 38802663)
-
(2004)
Journal of Neurochemistry
, vol.89
, Issue.6
, pp. 1417-1426
-
-
Cardoso, S.M.1
Santana, I.2
Swerdlow, R.H.3
Oliveira, C.R.4
-
63
-
-
78649981260
-
Functional genomics of brain aging and Alzheimer's disease: Focus on selective neuronal vulnerability
-
Wang X, Michaelis ML, Michaelis EK. Functional genomics of brain aging and Alzheimer's disease: focus on selective neuronal vulnerability. Curr Genomics 2010; 11: 618-633.
-
(2010)
Curr Genomics
, vol.11
, pp. 618-633
-
-
Wang, X.1
Michaelis, M.L.2
Michaelis, E.K.3
-
64
-
-
79952707903
-
Dimebon inhibits calcium-induced swelling of rat brain mitochondria but does not alter calcium retention or cytochrome C release
-
Naga KK, Geddes JW. Dimebon inhibits calcium-induced swelling of rat brain mitochondria but does not alter calcium retention or cytochrome C release. Neuromolecular Med 2011; 13: 31-36.
-
(2011)
Neuromolecular Med
, vol.13
, pp. 31-36
-
-
Naga, K.K.1
Geddes, J.W.2
-
65
-
-
84863944817
-
Dimebon ameliorates amyloid-beta induced impairments of mitochondrial form and function
-
Eckert SH, Eckmann J, Renner K, Eckert GP, Leuner K, Muller WE. Dimebon ameliorates amyloid-beta induced impairments of mitochondrial form and function. J Alzheimers Dis 2012; 31: 21-32.
-
(2012)
J Alzheimers Dis
, vol.31
, pp. 21-32
-
-
Eckert, S.H.1
Eckmann, J.2
Renner, K.3
Eckert, G.P.4
Leuner, K.5
Muller, W.E.6
-
66
-
-
79960910783
-
Latrepirdine increases cerebral glucose utilization in aged mice as measured by [18F]-fluorodeoxyglucose positron emission tomography
-
Day M, Chandran P, Luo F, Rustay NR, Markosyan S, LeBlond D et al. Latrepirdine increases cerebral glucose utilization in aged mice as measured by [18F]-fluorodeoxyglucose positron emission tomography. Neuroscience 2011; 189: 299-304.
-
(2011)
Neuroscience
, vol.189
, pp. 299-304
-
-
Day, M.1
Chandran, P.2
Luo, F.3
Rustay, N.R.4
Markosyan, S.5
Leblond, D.6
-
67
-
-
45549095784
-
Polyphenols as potential inhibitors of amyloid aggregation and toxicity: Possible significance to Alzheimer's disease
-
Bastianetto S, Krantic S, Quirion R. Polyphenols as potential inhibitors of amyloid aggregation and toxicity: possible significance to Alzheimer's disease. Mini Rev Med Chem 2008; 8: 429-435.
-
(2008)
Mini Rev Med Chem
, vol.8
, pp. 429-435
-
-
Bastianetto, S.1
Krantic, S.2
Quirion, R.3
-
68
-
-
63049119837
-
Ab aggregation and possible implications in Alzheimer's disease pathogenesis
-
Bharadwaj PR, Dubey AK, Masters CL, Martins RN, Macreadie IG. Ab aggregation and possible implications in Alzheimer's disease pathogenesis. J Cell Mol Med 2009; 13: 412-421.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 412-421
-
-
Bharadwaj, P.R.1
Dubey, A.K.2
Masters, C.L.3
Martins, R.N.4
Macreadie, I.G.5
-
69
-
-
33745922350
-
Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model
-
DOI 10.1038/nm1423, PII NM1423
-
McLaurin J, Kierstead ME, Brown ME, Hawkes CA, Lambermon MH, Phinney AL et al. Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model. Nat Med 2006; 12: 801-808. (Pubitemid 44050070)
-
(2006)
Nature Medicine
, vol.12
, Issue.7
, pp. 801-808
-
-
McLaurin, J.1
Kierstead, M.E.2
Brown, M.E.3
Hawkes, C.A.4
Lambermon, M.H.L.5
Phinney, A.L.6
Darabie, A.A.7
Cousins, J.E.8
French, J.E.9
Lan, M.F.10
Chen, F.11
Wong, S.S.N.12
Mount, H.T.J.13
Fraser, P.E.14
Westaway, D.15
George-Hyslop, P.St.16
-
70
-
-
67650140610
-
Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models
-
Yamashita M, Nonaka T, Arai T, Kametani F, Buchman VL, Ninkina N et al. Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models. FEBS Lett 2009; 583: 2419-2424.
-
(2009)
FEBS Lett
, vol.583
, pp. 2419-2424
-
-
Yamashita, M.1
Nonaka, T.2
Arai, T.3
Kametani, F.4
Buchman, V.L.5
Ninkina, N.6
-
71
-
-
85027944048
-
Dimebon reduces the levels of aggregated amyloidogenic protein forms in detergent-insoluble fractions in vivo
-
Ustyugov AA, Shelkovnikova TA, Kokhan VS, Khritankova IV, Peters O, Buchman VL et al. Dimebon reduces the levels of aggregated amyloidogenic protein forms in detergent-insoluble fractions in vivo. Bull Exp Biol Med 2012; 152: 731-733.
-
(2012)
Bull Exp Biol Med
, vol.152
, pp. 731-733
-
-
Ustyugov, A.A.1
Shelkovnikova, T.A.2
Kokhan, V.S.3
Khritankova, I.V.4
Peters, O.5
Buchman, V.L.6
-
72
-
-
76249083708
-
Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivo
-
Steele JW, Kim SH, Cirrito JR, Verges DK, Restivo JL, Westaway D et al. Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivo. Mol Neurodegener 2009; 4: 51.
-
(2009)
Mol Neurodegener
, vol.4
, pp. 51
-
-
Steele, J.W.1
Kim, S.H.2
Cirrito, J.R.3
Verges, D.K.4
Restivo, J.L.5
Westaway, D.6
-
73
-
-
41549155927
-
Endocytosis is required for synaptic activity-Dependent release of Amyloid-β In vivo
-
DOI 10.1016/j.neuron.2008.02.003, PII S0896627308001244
-
Cirrito JR, Kang JE, Lee J, Stewart FR, Verges DK, Silverio LM et al. Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo. Neuron 2008; 58: 42-51. (Pubitemid 351467029)
-
(2008)
Neuron
, vol.58
, Issue.1
, pp. 42-51
-
-
Cirrito, J.R.1
Kang, J.-E.2
Lee, J.3
Stewart, F.R.4
Verges, D.K.5
Silverio, L.M.6
Bu, G.7
Mennerick, S.8
Holtzman, D.M.9
-
74
-
-
68549127183
-
Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations
-
Tampellini D, Rahman N, Gallo EF, Huang Z, Dumont M, Capetillo-Zarate E et al. Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations. J Neurosci 2009; 29: 9704-9713.
-
(2009)
J Neurosci
, vol.29
, pp. 9704-9713
-
-
Tampellini, D.1
Rahman, N.2
Gallo, E.F.3
Huang, Z.4
Dumont, M.5
Capetillo-Zarate, E.6
-
75
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
DOI 10.1126/science.290.5497.1717
-
Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000; 290: 1717-1721. (Pubitemid 32004796)
-
(2000)
Science
, vol.290
, Issue.5497
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
76
-
-
72149122407
-
Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles
-
Ivachtchenko AV, Frolov EB, Mitkin OD, Tkachenko SE, Okun IM, Khvat AV. Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles. Bioorg Med Chem Lett 2010; 20: 78-82.
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 78-82
-
-
Ivachtchenko, A.V.1
Frolov, E.B.2
Mitkin, O.D.3
Tkachenko, S.E.4
Okun, I.M.5
Khvat, A.V.6
-
77
-
-
0034254956
-
2) and benzodiazepine receptors
-
DOI 10.1016/S0376-8716(99)00148-9, PII S0376871699001489
-
Glennon RA, Dukat M, Grella B, Hong S, Costantino L, Teitler M et al. Binding of beta-carbolines and related agents at serotonin (5-HT(2) and 5-HT(1A)), dopamine (D(2)) and benzodiazepine receptors. Drug Alcohol Depend 2000; 60: 121-132. (Pubitemid 30625015)
-
(2000)
Drug and Alcohol Dependence
, vol.60
, Issue.2
, pp. 121-132
-
-
Glennon, R.A.1
Dukat, M.2
Grella, B.3
Hong, S.-S.4
Costantino, L.5
Teitler, M.6
Smith, C.7
Egan, C.8
Davis, K.9
Mattson, M.V.10
-
78
-
-
0030779156
-
3H]MK-801 binding to the NMDA receptor in rabbit brain
-
DOI 10.1016/S0006-8993(97)00606-9, PII S0006899397006069
-
Du W, Aloyo VJ, Harvey JA. Harmaline competitively inhibits [3H]MK-801 binding to the NMDA receptor in rabbit brain. Brain Res 1997; 770: 26-29. (Pubitemid 27468046)
-
(1997)
Brain Research
, vol.770
, Issue.1-2
, pp. 26-29
-
-
Du, W.1
Aloyo, V.J.2
Harvey, J.A.3
-
79
-
-
76749127951
-
Beta-carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO)
-
Herraiz T, Gonzalez D, Ancin-Azpilicueta C, Aran VJ, Guillen H. Beta-carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO). Food Chem Toxicol 2010; 48: 839-845.
-
(2010)
Food Chem Toxicol
, vol.48
, pp. 839-845
-
-
Herraiz, T.1
Gonzalez, D.2
Ancin-Azpilicueta, C.3
Aran, V.J.4
Guillen, H.5
-
80
-
-
44149086353
-
Effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells
-
Yang YJ, Lee JJ, Jin CM, Lim SC, Lee MK. Effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells. Eur J Pharmacol 2008; 587: 57-64.
-
(2008)
Eur J Pharmacol
, vol.587
, pp. 57-64
-
-
Yang, Y.J.1
Lee, J.J.2
Jin, C.M.3
Lim, S.C.4
Lee, M.K.5
-
81
-
-
0028988115
-
Interaction of beta-carbolines with central dopaminergic transmission in mice: Structure-activity relationships
-
Pimpinella G, Palmery M. Interaction of beta-carbolines with central dopaminergic transmission in mice: structure-activity relationships. Neurosci Lett 1995; 189: 121-124.
-
(1995)
Neurosci Lett
, vol.189
, pp. 121-124
-
-
Pimpinella, G.1
Palmery, M.2
-
82
-
-
70349947061
-
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation
-
Gockler N, Jofre G, Papadopoulos C, Soppa U, Tejedor FJ, Becker W. Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation. FEBS J 2009; 276: 6324-6337.
-
(2009)
FEBS J
, vol.276
, pp. 6324-6337
-
-
Gockler, N.1
Jofre, G.2
Papadopoulos, C.3
Soppa, U.4
Tejedor, F.J.5
Becker, W.6
-
83
-
-
84890136786
-
-
Pfizer and Medivation Announce Results from Two Phase 3 Studies In Dimebon (latrepirdine) Alzheimer's Disease Development Program. Available at (accessed on 2010).
-
Pfizer and Medivation Announce Results from Two Phase 3 Studies In Dimebon (latrepirdine) Alzheimer's Disease Development Program. Available at: http://investors. medivation.com/releasedetail.cfm?ReleaseID=448818 (accessed on 2010).
-
-
-
-
84
-
-
84890174251
-
-
Concert: An Alzheimer's Disease Investigational Trial. Available at accessed on
-
Concert: An Alzheimer's Disease Investigational Trial. Available at: http:// concertstudy.com/index.html (accessed on 2010).
-
(2010)
-
-
-
85
-
-
84890148126
-
-
Constellation: An Alzheimer's disease Research Study. Available at accessed on
-
Constellation: An Alzheimer's disease Research Study. Available at: http:// www.constellationstudy.com/index.php (accessed on 2010).
-
(2010)
-
-
-
86
-
-
84864881933
-
Double-blind placebocontrolled randomized efficacy and safety trial of add-on treatment of dimebon plus risperidone in schizophrenic patients during transition from acute psychotic episode to remission
-
Morozova MA, Beniashvili AG, Lepilkina TA, Rupchev GE. Double-blind placebocontrolled randomized efficacy and safety trial of add-on treatment of dimebon plus risperidone in schizophrenic patients during transition from acute psychotic episode to remission. Psychiatr Danub 2012; 24: 159-166.
-
(2012)
Psychiatr Danub
, vol.24
, pp. 159-166
-
-
Morozova, M.A.1
Beniashvili, A.G.2
Lepilkina, T.A.3
Rupchev, G.E.4
|