Balancing grk2 and epac1 levels prevents and relieves chronic pain

Journal of Clinical Investigation

Volumn 123, Issue 12, 2013, Pages 5023-5034

  Wang, Huijing ^a,b   Heijnen, Cobi J ^a   Van Velthoven, Cindy T J ^a   Willemen, Hanneke L D M ^a   Ishikawa, Yoshihiro ^c   Zhang, Xinna ^a   Sood, Anil K ^a   Vroon, Anne ^a   Eijkelkamp, Niels ^a   Kavelaars, Annemieke ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b FUDAN UNIVERSITY   (China)

^c YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CARRAGEENAN; G PROTEIN COUPLED RECEPTOR KINASE 2; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; FEMALE; GENE TRANSFER; HYPERALGESIA; INFLAMMATORY PAIN; MOUSE; NERVE CELL; NOCICEPTION; NONHUMAN; PAIN RECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NERVE CELL; SPINAL GANGLION;

ANIMALS; CARRAGEENAN; CATTLE; CHRONIC PAIN; CYCLIC AMP; DINOPROSTONE; FEMALE; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC THERAPY; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HINDLIMB; HYPERALGESIA; INJECTIONS, SPINAL; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; NOCICEPTORS; OLIGONUCLEOTIDES, ANTISENSE; OLIGOPEPTIDES; RECOMBINANT FUSION PROTEINS; SCIATIC NERVE; SECOND MESSENGER SYSTEMS; SENSORY RECEPTOR CELLS;

EID: 84890089485     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI66241     Document Type: Article

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