-
2
-
-
77957768017
-
Translational control mechanisms in long-lasting synaptic plasticity and memory
-
C. Gkogkas, N. Sonenberg, and M. Costa-Mattioli Translational control mechanisms in long-lasting synaptic plasticity and memory J Biol Chem 285 2010 31913 31917
-
(2010)
J Biol Chem
, vol.285
, pp. 31913-31917
-
-
Gkogkas, C.1
Sonenberg, N.2
Costa-Mattioli, M.3
-
3
-
-
77950864433
-
Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration
-
S. Yoo, E.A. van Niekerk, T.T. Merianda, and J.L. Twiss Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration Exp Neurol 223 2010 19 27
-
(2010)
Exp Neurol
, vol.223
, pp. 19-27
-
-
Yoo, S.1
Van Niekerk, E.A.2
Merianda, T.T.3
Twiss, J.L.4
-
4
-
-
58149469090
-
Translational control of long-lasting synaptic plasticity and memory
-
M. Costa-Mattioli, W.S. Sossin, E. Klann, and N. Sonenberg Translational control of long-lasting synaptic plasticity and memory Neuron 61 2009 10 26
-
(2009)
Neuron
, vol.61
, pp. 10-26
-
-
Costa-Mattioli, M.1
Sossin, W.S.2
Klann, E.3
Sonenberg, N.4
-
5
-
-
12144254738
-
Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration
-
P. Verma, S. Chierzi, A.M. Codd, D.S. Campbell, R.L. Meyer, C.E. Holt, and J.W. Fawcett Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration J Neurosci 25 2005 331 342
-
(2005)
J Neurosci
, vol.25
, pp. 331-342
-
-
Verma, P.1
Chierzi, S.2
Codd, A.M.3
Campbell, D.S.4
Meyer, R.L.5
Holt, C.E.6
Fawcett, J.W.7
-
6
-
-
1342322145
-
Translational control by MAPK signaling in long-term synaptic plasticity and memory
-
R.J. Kelleher III, A. Govindarajan, H.Y. Jung, H. Kang, and S. Tonegawa Translational control by MAPK signaling in long-term synaptic plasticity and memory Cell 116 2004 467 479
-
(2004)
Cell
, vol.116
, pp. 467-479
-
-
Kelleher Iii, R.J.1
Govindarajan, A.2
Jung, H.Y.3
Kang, H.4
Tonegawa, S.5
-
7
-
-
72449169993
-
A rapamycin-sensitive signaling pathway is essential for the full expression of persistent pain states
-
S.M. Geranton, L. Jimenez-Diaz, C. Torsney, K.K. Tochiki, S.A. Stuart, J.L. Leith, B.M. Lumb, and S.P. Hunt A rapamycin-sensitive signaling pathway is essential for the full expression of persistent pain states J Neurosci 29 2009 15017 15027
-
(2009)
J Neurosci
, vol.29
, pp. 15017-15027
-
-
Geranton, S.M.1
Jimenez-Diaz, L.2
Torsney, C.3
Tochiki, K.K.4
Stuart, S.A.5
Leith, J.L.6
Lumb, B.M.7
Hunt, S.P.8
-
8
-
-
44849127752
-
Local translation in primary afferent fibers regulates nociception
-
L. Jimenez-Diaz, S.M. Geranton, G.M. Passmore, J.L. Leith, A.S. Fisher, L. Berliocchi, A.K. Sivasubramaniam, A. Sheasby, B.M. Lumb, and S.P. Hunt Local translation in primary afferent fibers regulates nociception PLoS ONE 3 2008 e1961
-
(2008)
PLoS ONE
, vol.3
, pp. 1961
-
-
Jimenez-Diaz, L.1
Geranton, S.M.2
Passmore, G.M.3
Leith, J.L.4
Fisher, A.S.5
Berliocchi, L.6
Sivasubramaniam, A.K.7
Sheasby, A.8
Lumb, B.M.9
Hunt, S.P.10
-
9
-
-
77956871995
-
Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat
-
C.O. Asante, V.C. Wallace, and A.H. Dickenson Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat J Pain 11 2010 1356 1367
-
(2010)
J Pain
, vol.11
, pp. 1356-1367
-
-
Asante, C.O.1
Wallace, V.C.2
Dickenson, A.H.3
-
10
-
-
77955277478
-
Mammalian target of rapamycin in spinal cord neurons mediates hypersensitivity induced by peripheral inflammation
-
G.E. Norsted, S. Codeluppi, J.A. Gregory, J. Steinauer, and C.I. Svensson Mammalian target of rapamycin in spinal cord neurons mediates hypersensitivity induced by peripheral inflammation Neuroscience 169 2010 1392 1402
-
(2010)
Neuroscience
, vol.169
, pp. 1392-1402
-
-
Norsted, G.E.1
Codeluppi, S.2
Gregory, J.A.3
Steinauer, J.4
Svensson, C.I.5
-
11
-
-
38449091182
-
Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: Role of mGluR1/5 and mTOR
-
T.J. Price, M.H. Rashid, M. Millecamps, R. Sanoja, J.M. Entrena, and F. Cervero Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR J Neurosci 27 2007 13958 13967
-
(2007)
J Neurosci
, vol.27
, pp. 13958-13967
-
-
Price, T.J.1
Rashid, M.H.2
Millecamps, M.3
Sanoja, R.4
Entrena, J.M.5
Cervero, F.6
-
12
-
-
79951538149
-
Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia
-
Q. Xu, B. Fitzsimmons, J. Steinauer, A.O. Neill, A.C. Newton, X.Y. Hua, and T.L. Yaksh Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia J Neurosci 31 2011 2113 2124
-
(2011)
J Neurosci
, vol.31
, pp. 2113-2124
-
-
Xu, Q.1
Fitzsimmons, B.2
Steinauer, J.3
Neill, A.O.4
Newton, A.C.5
Hua, X.Y.6
Yaksh, T.L.7
-
13
-
-
80054991423
-
Systemic inhibition of the mammalian target of rapamycin (mTOR) pathway reduces neuropathic pain in mice
-
I. Obara, K.K. Tochiki, S.M. Geranton, F.B. Carr, B.M. Lumb, Q. Liu, and S.P. Hunt Systemic inhibition of the mammalian target of rapamycin (mTOR) pathway reduces neuropathic pain in mice Pain 2011
-
(2011)
Pain
-
-
Obara, I.1
Tochiki, K.K.2
Geranton, S.M.3
Carr, F.B.4
Lumb, B.M.5
Liu, Q.6
Hunt, S.P.7
-
14
-
-
78149479471
-
IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex
-
O.K. Melemedjian, M.N. Asiedu, D.V. Tillu, K.A. Peebles, J. Yan, N. Ertz, G.O. Dussor, and T.J. Price IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex J Neurosci 30 2010 15113 15123
-
(2010)
J Neurosci
, vol.30
, pp. 15113-15123
-
-
Melemedjian, O.K.1
Asiedu, M.N.2
Tillu, D.V.3
Peebles, K.A.4
Yan, J.5
Ertz, N.6
Dussor, G.O.7
Price, T.J.8
-
15
-
-
67449115950
-
Translating nociceptor sensitivity: The role of axonal protein synthesis in nociceptor physiology
-
T.J. Price, and S.M. Geranton Translating nociceptor sensitivity: the role of axonal protein synthesis in nociceptor physiology Eur J Neurosci 29 2009 2253 2263
-
(2009)
Eur J Neurosci
, vol.29
, pp. 2253-2263
-
-
Price, T.J.1
Geranton, S.M.2
-
16
-
-
80053174960
-
Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain
-
O.K. Melemedjian, M.N. Asiedu, D.V. Tillu, R. Sanoja, J. Yan, A. Lark, A. Khoutorsky, J. Johnson, K.A. Peebles, and T. Lepow Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain Mol Pain 7 2011 70
-
(2011)
Mol Pain
, vol.7
, pp. 70
-
-
Melemedjian, O.K.1
Asiedu, M.N.2
Tillu, D.V.3
Sanoja, R.4
Yan, J.5
Lark, A.6
Khoutorsky, A.7
Johnson, J.8
Peebles, K.A.9
Lepow, T.10
-
17
-
-
0035256911
-
The molecular dynamics of pain control
-
S.P. Hunt, and P.W. Mantyh The molecular dynamics of pain control Nat Rev Neurosci 2 2001 83 91
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 83-91
-
-
Hunt, S.P.1
Mantyh, P.W.2
-
18
-
-
78149359626
-
Nociceptor sensitization in pain pathogenesis
-
M.S. Gold, and G.F. Gebhart Nociceptor sensitization in pain pathogenesis Nat Med 16 2010 1248 1257
-
(2010)
Nat Med
, vol.16
, pp. 1248-1257
-
-
Gold, M.S.1
Gebhart, G.F.2
-
19
-
-
33847217610
-
Mechanisms of sensory transduction in the skin
-
E.A. Lumpkin, and M.J. Caterina Mechanisms of sensory transduction in the skin Nature 445 2007 858 865
-
(2007)
Nature
, vol.445
, pp. 858-865
-
-
Lumpkin, E.A.1
Caterina, M.J.2
-
20
-
-
0034853835
-
Roles of capsaicin-insensitive nociceptors in cutaneous pain and secondary hyperalgesia
-
W. Magerl, P.N. Fuchs, R.A. Meyer, and R.D. Treede Roles of capsaicin-insensitive nociceptors in cutaneous pain and secondary hyperalgesia Brain 124 2001 1754 1764
-
(2001)
Brain
, vol.124
, pp. 1754-1764
-
-
Magerl, W.1
Fuchs, P.N.2
Meyer, R.A.3
Treede, R.D.4
-
21
-
-
80051621139
-
Allodynia mediated by C-tactile afferents in human hairy skin
-
S.S. Nagi, T.K. Rubin, D.K. Chelvanayagam, V.G. Macefield, and D.A. Mahns Allodynia mediated by C-tactile afferents in human hairy skin J Physiol 589 2011 4065 4075
-
(2011)
J Physiol
, vol.589
, pp. 4065-4075
-
-
Nagi, S.S.1
Rubin, T.K.2
Chelvanayagam, D.K.3
MacEfield, V.G.4
Mahns, D.A.5
-
23
-
-
77952007543
-
Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony
-
K.G. Foster, and D.C. Fingar Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony J Biol Chem 285 2010 14071 14077
-
(2010)
J Biol Chem
, vol.285
, pp. 14071-14077
-
-
Foster, K.G.1
Fingar, D.C.2
-
24
-
-
17444431201
-
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis
-
L. Ma, Z. Chen, H. Erdjument-Bromage, P. Tempst, and P.P. Pandolfi Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis Cell 121 2005 179 193
-
(2005)
Cell
, vol.121
, pp. 179-193
-
-
Ma, L.1
Chen, Z.2
Erdjument-Bromage, H.3
Tempst, P.4
Pandolfi, P.P.5
-
26
-
-
58149147512
-
Schwann cell to axon transfer of ribosomes: Toward a novel understanding of the role of glia in the nervous system
-
F. Court, W.T. Hendriks, H.D. Macgillavry, J. Alvarez, and M.J. van Schwann cell to axon transfer of ribosomes: toward a novel understanding of the role of glia in the nervous system J Neurosci 28 2008 11024 11029
-
(2008)
J Neurosci
, vol.28
, pp. 11024-11029
-
-
Court, F.1
Hendriks, W.T.2
MacGillavry, H.D.3
Alvarez, J.4
Van, M.J.5
-
27
-
-
33745841571
-
RNA trafficking in axons
-
J.R. Sotelo-Silveira, A. Calliari, A. Kun, E. Koenig, and J.R. Sotelo RNA trafficking in axons Traffic 7 2006 508 515
-
(2006)
Traffic
, vol.7
, pp. 508-515
-
-
Sotelo-Silveira, J.R.1
Calliari, A.2
Kun, A.3
Koenig, E.4
Sotelo, J.R.5
-
28
-
-
33747250338
-
The RNA binding and transport proteins staufen and fragile X mental retardation protein are expressed by rat primary afferent neurons and localize to peripheral and central axons
-
T.J. Price, C.M. Flores, F. Cervero, and K.M. Hargreaves The RNA binding and transport proteins staufen and fragile X mental retardation protein are expressed by rat primary afferent neurons and localize to peripheral and central axons Neuroscience 141 2006 2107 2116
-
(2006)
Neuroscience
, vol.141
, pp. 2107-2116
-
-
Price, T.J.1
Flores, C.M.2
Cervero, F.3
Hargreaves, K.M.4
-
29
-
-
34648840173
-
Dendritic mRNA: Transport, translation and function
-
C.R. Bramham, and D.G. Wells Dendritic mRNA: transport, translation and function Nat Rev Neurosci 8 2007 776 789
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 776-789
-
-
Bramham, C.R.1
Wells, D.G.2
-
30
-
-
4644250844
-
Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization
-
Z.Y. Zhuang, H. Xu, D.E. Clapham, and R.R. Ji Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization J Neurosci 24 2004 8300 8309
-
(2004)
J Neurosci
, vol.24
, pp. 8300-8309
-
-
Zhuang, Z.Y.1
Xu, H.2
Clapham, D.E.3
Ji, R.R.4
-
31
-
-
79960349522
-
MTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression
-
B. Ekim, B. Magnuson, H.A. Acosta-Jaquez, J.A. Keller, E.P. Feener, and D.C. Fingar mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression Mol Cell Biol 31 2011 2787 2801
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2787-2801
-
-
Ekim, B.1
Magnuson, B.2
Acosta-Jaquez, H.A.3
Keller, J.A.4
Feener, E.P.5
Fingar, D.C.6
-
32
-
-
71449102022
-
Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors
-
R.P. Seal, X. Wang, Y. Guan, S.N. Raja, C.J. Woodbury, A.I. Basbaum, and R.H. Edwards Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors Nature 462 2009 651 655
-
(2009)
Nature
, vol.462
, pp. 651-655
-
-
Seal, R.P.1
Wang, X.2
Guan, Y.3
Raja, S.N.4
Woodbury, C.J.5
Basbaum, A.I.6
Edwards, R.H.7
-
33
-
-
66749156637
-
Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli
-
D.J. Cavanaugh, H. Lee, L. Lo, S.D. Shields, M.J. Zylka, A.I. Basbaum, and D.J. Anderson Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli Proc Natl Acad Sci U S A 106 2009 9075 9080
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9075-9080
-
-
Cavanaugh, D.J.1
Lee, H.2
Lo, L.3
Shields, S.D.4
Zylka, M.J.5
Basbaum, A.I.6
Anderson, D.J.7
-
34
-
-
67349268926
-
Translating nociceptive processing into human pain models
-
M. Schmelz Translating nociceptive processing into human pain models Exp Brain Res 196 2009 173 178
-
(2009)
Exp Brain Res
, vol.196
, pp. 173-178
-
-
Schmelz, M.1
-
35
-
-
36348950449
-
Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
-
R.J. Dowling, M. Zakikhani, I.G. Fantus, M. Pollak, and N. Sonenberg Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells Cancer Res 67 2007 10804 10812
-
(2007)
Cancer Res
, vol.67
, pp. 10804-10812
-
-
Dowling, R.J.1
Zakikhani, M.2
Fantus, I.G.3
Pollak, M.4
Sonenberg, N.5
-
36
-
-
68949212217
-
Efficacy, tolerance, and safety of mammalian target of rapamycin inhibitors as rescue immunosuppressants in liver transplantation
-
J.M. Alamo, L. Barrera, M.D. Casado, C. Bernal, L.M. Marin, G. Suarez, L. Sanchez-Moreno, R. Jimenez, J.M. Suarez-Grau, and J.M. Sousa Efficacy, tolerance, and safety of mammalian target of rapamycin inhibitors as rescue immunosuppressants in liver transplantation Transplant Proc 41 2009 2181 2183
-
(2009)
Transplant Proc
, vol.41
, pp. 2181-2183
-
-
Alamo, J.M.1
Barrera, L.2
Casado, M.D.3
Bernal, C.4
Marin, L.M.5
Suarez, G.6
Sanchez-Moreno, L.7
Jimenez, R.8
Suarez-Grau, J.M.9
Sousa, J.M.10
-
37
-
-
77957903550
-
Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)- 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer
-
Q. Liu, J.W. Chang, J. Wang, S.A. Kang, C.C. Thoreen, A. Markhard, W. Hur, J. Zhang, T. Sim, D.M. Sabatini, and N.S. Gray Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl) benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer J Med Chem 53 2010 7146 7155
-
(2010)
J Med Chem
, vol.53
, pp. 7146-7155
-
-
Liu, Q.1
Chang, J.W.2
Wang, J.3
Kang, S.A.4
Thoreen, C.C.5
Markhard, A.6
Hur, W.7
Zhang, J.8
Sim, T.9
Sabatini, D.M.10
Gray, N.S.11
-
38
-
-
64949083602
-
Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy
-
D.K. Thakor, A. Lin, Y. Matsuka, E.M. Meyer, S. Ruangsri, I. Nishimura, and I. Spigelman Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy Mol Pain 5 2009 14
-
(2009)
Mol Pain
, vol.5
, pp. 14
-
-
Thakor, D.K.1
Lin, A.2
Matsuka, Y.3
Meyer, E.M.4
Ruangsri, S.5
Nishimura, I.6
Spigelman, I.7
-
39
-
-
78650474986
-
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization
-
L.F. Gumy, G.S. Yeo, Y.C. Tung, K.H. Zivraj, D. Willis, G. Coppola, B.Y. Lam, J.L. Twiss, C.E. Holt, and J.W. Fawcett Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization RNA 17 2011 85 98
-
(2011)
RNA
, vol.17
, pp. 85-98
-
-
Gumy, L.F.1
Yeo, G.S.2
Tung, Y.C.3
Zivraj, K.H.4
Willis, D.5
Coppola, G.6
Lam, B.Y.7
Twiss, J.L.8
Holt, C.E.9
Fawcett, J.W.10
-
40
-
-
77649097483
-
An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons
-
C. Andreassi, C. Zimmermann, R. Mitter, S. Fusco, V.S. De, A. Saiardi, and A. Riccio An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons Nat Neurosci 13 2010 291 301
-
(2010)
Nat Neurosci
, vol.13
, pp. 291-301
-
-
Andreassi, C.1
Zimmermann, C.2
Mitter, R.3
Fusco, S.4
De, V.S.5
Saiardi, A.6
Riccio, A.7
-
41
-
-
79958068191
-
Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling
-
Y. Pan, E.A. Schroeder, A. Ocampo, A. Barrientos, and G.S. Shadel Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling Cell Metab 13 2011 668 678
-
(2011)
Cell Metab
, vol.13
, pp. 668-678
-
-
Pan, Y.1
Schroeder, E.A.2
Ocampo, A.3
Barrientos, A.4
Shadel, G.S.5
|