A critical role of the cAMP sensor Epac in switching protein kinase signalling in prostaglandin E2-induced potentiation of P2X3 receptor currents in inflamed rats

Journal of Physiology

Volumn 584, Issue 1, 2007, Pages 191-203

  Wang, Congying ^a   Gu, Yanping ^a   Li, Guang Wen ^a   Huang, Li Yen Mae ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; ADENOSINE TRIPHOSPHATE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FREUND ADJUVANT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROSTAGLANDIN E2; PROTEIN EPAC; PROTEIN KINASE; PROTEIN KINASE C EPSILON; PURINE P2X3 RECEPTOR; UNCLASSIFIED DRUG; EPAC1 PROTEIN; PURINERGIC P2X3 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SENSITIZATION; SIGNAL TRANSDUCTION; SPINAL GANGLION; UPREGULATION; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; GANGLIA, SPINAL; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INFLAMMATION; NOCICEPTORS; PROTEIN KINASE C-EPSILON; RATS; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION;

EID: 34848912884     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.135616     Document Type: Article

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