Gene transfer of NMDAR1 subunit sequences to the rat CNS using herpes simplex virus vectors interfered with habituation

Cellular and Molecular Neurobiology

Volumn 22, Issue 3, 2002, Pages 303-314

  Cheli, V T ^a   Adrover, M F ^a   Blanco, C ^a   Verde, E Rial ^a   Guyot Revol, V ^b   Vidal, R ^a   Martin, E ^a   Alche L ^a   Sanchez, G ^a   Acerbo, M ^a   Epstein, A L ^b   Jerusalinsky, D ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

Herpes simplex vectors; Hippocampus; Learning; Memory; NMDA receptors; NR1 subunit

Indexed keywords

GREEN FLUORESCENT PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBUNIT; VIRUS VECTOR;

AMINO ACID SEQUENCE; AMPLICON; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; CELL LINE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; GENE TRANSFER; HABITUATION; HERPES SIMPLEX VIRUS 1; HIPPOCAMPUS; IMMUNOFLUORESCENCE; MALE; NEUROTROPISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PYRAMIDAL NERVE CELL; RAT; RETROGRADE AMNESIA; WESTERN BLOTTING;

ANIMALS; BEHAVIOR, ANIMAL; CRICETINAE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HABITUATION, PSYCHOPHYSIOLOGIC; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING; LUMINESCENT PROTEINS; MALE; MEMORY; MEMORY DISORDERS; OLIGONUCLEOTIDES, ANTISENSE; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SIMPLEXVIRUS; SYNAPTIC TRANSMISSION;

ANIMALIA; HERPES; HUMAN HERPESVIRUS 1; RATTUS NORVEGICUS; SIMPLEXVIRUS;

EID: 18744387688     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020720001865     Document Type: Article

References (38)

1. Alonso, M., Quillfeldt, J., Kornisiuk, E., Ons, S., Rial, Verde, E., Castro, Vasques, V., Roca Vianna, M., Rocha Viegas, L., Blanco, C., and Jerusalinsky, D. (1999). NMDA and AMPA receptor modification after training depends on the learning tas. J. Neurochem. 73:S136C.
2. Bliss, T. V. P., and Collingridge, G. L. (1993). A synaptic model of memory: Long-term potentiation of de hippocampus. Nature 361:31-39.
3. Bliss, T. V. P., and Lomo, T. (1973). Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J. Physiol. Lond. 232:331-356.
4. Cain, D. P. (1998). Testing the NMDA, long-term potentiation, and cholinergic hypotheses of spatial learning. Neurosci. Biobehav. Rev. 22(2):181-193.
5. 3[H] AMPA receptor binding in the rat hippocampal formation. Neurobiol. Learn. Mem. 64:257-264.
6. Collingridge, G. L., and Singer, W. (1990). Excitatory amino acid receptors and synapsis plasticity. Trends Pharmacol. Sci. 1:290-296.
7. Davis, S., Butcher, S. P., and Morris, R. G. M. (1992). The NMDA receptors antagonist D-2-amino-5-phosphopentanoate (D-AP5) impairs spatial learning and LTP in vivo at intracerebral concentrations comparable to those that block LTP in vitro. J. Neurosci. 12:21-34.
8. DeLuca, N., McCarthy, A., and Schalfer, P. (1985). Isolation an characterization of deletion mutans of Herpes Simplex Virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J. Virol. 56(2):558-570.
9. DeRobertis, E., Alberici, M., Rodríguez de Lorez Arnaiz, G., and Azcurra, J. (1966). Isolation of different types of synaptic membranes from the brain cortex. Life Sci. 5:577-582.
10. Epstein, A. L. (1995). HSV-1 amplicons. Advantages and disadvantages of a versatile vector system. Restor. Neurol. Neurosci. 8:41-43.
11. Forrest, D., Yuzaki, M., Soares, H. D., Ng, L., Luk, D. C., Sheng, M., Stewart, C. L., Morgan, J. I., Connor, J. A., and Curran, T. (1994). Targeted disruption of NMDA receptor gene abolishes NMDA response and results in neonatal death. Neuron 13:325-338.
12. Hebb, D. O. (1949). The Organization of Behavior, Wiley, New York.
13. Hlinák, Z., and Krjcí, I. (1998). Concurrent administration of subeffective doses of scopolamine and MK-801 produces a short-term amnesia for the elevated plus-maze in mice. Behav. Brain Res.91:83-89.
14. Jarrard, L. E. (1993). On the role of the hippocampus in learning and memory in the rat. Behav. Neural. Biol. 60:9-26.
15. Kammesheidt, A., Kato, K., Ito, K., and Sumikawa, K. (1997). Adenivirus-mediated NMDA receptor knockuots in the rat hippocampal CA1 region. Neuro Report 8:3635-3638.
16. Leib, D. A., and Olivo, P. D. (1994). Gene delivery to neurons: Is herpes simplex virus the right tool for the job? Bioessays. 15:547-554.
17. Li, Y., Erzurumlu, R., Chen, C., Jhaveri, S., and Tonegawa, S. (1994). Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell 76:427-437.
18. Logvinoff, C., and Epstein, A. L. (2000). Genetic engineering of herpes simplex virus and vector genomes carrying loxP sites in cells expressing Cre recombinase. Virology 267:102-110.
19. Lomo, T. (1966). Frequency potentiation of excitatory synaptic activity in the dentate area of the hippocampal formation. Acta Physiol. Scand. 68(SDuppl. 277):128.
20. Lowenstein, P. R., Fournel, S., Bain, D., Tomasec, P., clissold, P., Castro, M. G., and Epstein, A. L. (1994). Herpes simplex virus 1 (HSV-1) helper co-infection affects the distribution of an amplicon encoded protein in glia. Neuro Report 5:1625-1630.
21. Machuca, I., Jacquemont, B., and Epstein, A. L. (1986). Multiple adjacent or overlapping loci affecting the level of gC and cell fusion mapped by intratypic recombinants of HSV-1. Virology 150:117-125.
22. McHugh, T. J., Blum, K. I., Tsien, J. L., Tonegawa, S., and Wilson, M. A. (1996). Impaired hippocampal representation on space in CA1-specific NMDAR1 knockout mice. Cell 87:1339-1349.
23. Moriyoshi, K., Masu, M., Ishii, T., Shigemoyo, R., Mizumo, N., and Nakanishi, S. (1991). Molecular cloning and characterization of the rat NMDA receptor. Nature 354:31-37.
24. Morris, R. G. M. (1990). The role of NMDA receptors in certain types of learning and memory. In Squire, I. R., and Lindenlaub, E. (eds.), The Biology of Memory (Symposta Medica Hoechst 23), F. K. Schatteur verlag, Stuttgart, New York, pp. 229-316.
25. Morris, R. G. M., Anderson, A., Lynch, G. S., and Baudry, M. (1986). Selective impaired of learning and blockade of long-term potentiation by and N-methyl-D-aspartate receptor antagonist, AP5. Nature 319:774-776.
26. Morris, R. G. M., Garrud, P., Rowlins, J. N. P., and O'Keefe, J. (1982). Place navigation impaired in rats with hippocampal lessions. Nature 297:681-683.
27. Nakanishi, S. (1992). Molecular diversity of glutamate receptors and implications for brain function. Science 258:597-603.
28. Nakanishi, S., Nakajima, Y., Masu, M., Ueda, Y., Nakahara, K., Watanabe, D., Yamaguchi, S., Kawabata, S., and Okada, M. (1998). Glutamate receptors: Brain and signal transduction. Brain Res. Rev. 26:230-235.
29. O'Keefe, J., and Nadel, L. (1978). The Hippocampus and Cognitive Map, Clarendon Press, Oxford.
30. Paterson, T., Everett, R. A. (1990). Prominent serine-rich region in Vmw 175, the major transcriptional regulator protein of herpes simplex virus type 1, is not essential for virus growth in tissue culture. J. Gen. Virol. 71:1775-1783.
31. Paxinos, G., and Watson, C. (1996) The Rat Brain in Stereotaxic Coordinates, Academic Press, Orlando, FL.
32. Scoville, W. B., Milner, B. (1957). Lost of recent memory after bilateral hippocampal lesions. J. Neurol. Neurosurg. Psychiatry 20:11-12.
33. Silva, A., Paylir, R., Wehner, J., and Tonegawa, S. (1992a). Impaired spatial learning in a-calcium calmodulin kinase II mutant mice. Science 257:206-211.
34. Silva, A., Stevens, C. F., Tonegawa, S., and Wang, Y. (1992b). Deficient hippocampal long-term potentiation α-calcium calmodulin kinase II mutant mice. Science 257:201-206.
35. Simonato, M., Manservigi, R., Marconi, P., and Glorioso, J. (2000). Gene transfer into neurones for the molecular analysis of behaviour: Focus on herpes simplex vactor. Trends Neurosci. 23(5):183-190.
36. Speate, R. R., and Frenkel, N. (1982). The herpes simplex virus amplicon: A new eukaryotic defective-virus cloning-amplifying vector. Cell 30:295-304.
37. Tsien, J. Z., Chen, D. F., Gerber, D., Tom, C., Mercer, E. H., Anderson, D. J., Mayford, M., Kandel, D. R., and Tonegawa, S. (1996). Subregion-and cell type-restricted gene knockout in mouse brain. Cell 87:1317-1326.
38. Zola-Morgan, S., Squire, L. R., and Amaral, D. (1986). Human amnesia and the medical temporal region: Enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus. J. Neurosci. 6:2950-2967.