Topical hypochlorite ameliorates NF-κB-mediated skin diseases in mice

Journal of Clinical Investigation

Volumn 123, Issue 12, 2013, Pages 5361-5370

  Leung, Thomas H ^a,b   Zhang, Lillian F ^a   Wang, Jing ^a   Ning, Shoucheng ^b   Knox, Susan J ^b   Kim, Seung K ^a,c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b Department of Dermatology ^*  (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYSTEINE; HYPOCHLORITE SODIUM; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; MONOCYTE CHEMOTACTIC PROTEIN 1; RAD50 PROTEIN; TRANSCRIPTION FACTOR NRF2;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CUTANEOUS PARAMETERS; DISEASE SEVERITY; ENZYME INACTIVATION; GENE INDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; JUVENILE ANIMAL; KERATINOCYTE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RADIATION DERMATITIS; REPORTER GENE; SIGNAL TRANSDUCTION; SKIN DISEASE; SKIN ULCER; SKINFOLD THICKNESS; TOPICAL TREATMENT;

ADMINISTRATION, CUTANEOUS; AMINO ACID SUBSTITUTION; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; CHEMOKINE CCL2; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYSTEINE; DNA REPAIR; DRUG EVALUATION, PRECLINICAL; FEMALE; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; HYPOCHLOROUS ACID; I-KAPPA B KINASE; KERATINOCYTES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NF-KAPPA B; OXIDANTS; OXIDATION-REDUCTION; RADIODERMATITIS; SKIN AGING; SKIN DISEASES; SKIN ULCER; SUPEROXIDE DISMUTASE; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84890042917     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI70895     Document Type: Article

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